IL80268A - Alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide n-oxides,their preparation and pharmaceutical compositions containing them - Google Patents
Alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide n-oxides,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL80268A IL80268A IL80268A IL8026886A IL80268A IL 80268 A IL80268 A IL 80268A IL 80268 A IL80268 A IL 80268A IL 8026886 A IL8026886 A IL 8026886A IL 80268 A IL80268 A IL 80268A
- Authority
- IL
- Israel
- Prior art keywords
- alpha
- pharmaceutical compositions
- 6alkyl
- piperidinebutanamide
- diaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Electric Double-Layer Capacitors Or The Like (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78656685A | 1985-10-11 | 1985-10-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL80268A0 IL80268A0 (en) | 1987-01-30 |
| IL80268A true IL80268A (en) | 1991-03-10 |
Family
ID=25138953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL80268A IL80268A (en) | 1985-10-11 | 1986-10-09 | Alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide n-oxides,their preparation and pharmaceutical compositions containing them |
Country Status (33)
| Country | Link |
|---|---|
| EP (1) | EP0219898B1 (nl) |
| JP (1) | JPS6287569A (nl) |
| KR (1) | KR940001772B1 (nl) |
| CN (1) | CN1015453B (nl) |
| AT (1) | ATE53022T1 (nl) |
| AU (1) | AU583429B2 (nl) |
| BG (1) | BG61320B2 (nl) |
| CA (1) | CA1332236C (nl) |
| CY (1) | CY1603A (nl) |
| DE (1) | DE3671442D1 (nl) |
| DK (1) | DK173954B1 (nl) |
| DZ (1) | DZ997A1 (nl) |
| EG (1) | EG18126A (nl) |
| ES (1) | ES2002001A6 (nl) |
| FI (1) | FI83642C (nl) |
| GR (1) | GR862493B (nl) |
| HK (1) | HK52491A (nl) |
| HU (1) | HU196180B (nl) |
| IE (1) | IE59519B1 (nl) |
| IL (1) | IL80268A (nl) |
| LT (1) | LT2086B (nl) |
| LV (2) | LV5042A3 (nl) |
| NL (1) | NL950025I2 (nl) |
| NO (2) | NO168640C (nl) |
| NZ (1) | NZ217818A (nl) |
| PH (1) | PH22510A (nl) |
| PT (1) | PT83506B (nl) |
| SG (1) | SG46291G (nl) |
| SU (1) | SU1443798A3 (nl) |
| TN (1) | TNSN86138A1 (nl) |
| ZA (1) | ZA867713B (nl) |
| ZM (1) | ZM9486A1 (nl) |
| ZW (1) | ZW20386A1 (nl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2088273C (en) * | 1990-08-09 | 1996-05-14 | Daniel Louis Barone | Processes for formulating a solid oral dosage form of loperamide compounds |
| US5434158A (en) * | 1994-04-26 | 1995-07-18 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin-3 antagonists |
| WO1997024325A1 (en) * | 1995-12-28 | 1997-07-10 | Takeda Chemical Industries, Ltd. | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS |
| AU3254499A (en) * | 1998-03-06 | 1999-09-20 | Janssen Pharmaceutica N.V. | Glycine transport inhibitors |
| KR101315751B1 (ko) * | 2011-05-30 | 2013-10-10 | 주식회사 엔지켐생명과학 | 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3714159A (en) * | 1971-03-30 | 1973-01-30 | Janssen Pharmaceutica Nv | 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides |
| US4002618A (en) * | 1976-02-23 | 1977-01-11 | G. D. Searle & Co. | 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles |
-
1986
- 1986-09-22 CA CA000518722A patent/CA1332236C/en not_active Expired - Lifetime
- 1986-09-26 ES ES8602220A patent/ES2002001A6/es not_active Expired
- 1986-09-30 KR KR1019860008184A patent/KR940001772B1/ko not_active IP Right Cessation
- 1986-09-30 EP EP86201676A patent/EP0219898B1/en not_active Expired - Lifetime
- 1986-09-30 AT AT86201676T patent/ATE53022T1/de active
- 1986-09-30 DE DE8686201676T patent/DE3671442D1/de not_active Expired - Lifetime
- 1986-10-02 GR GR862493A patent/GR862493B/el unknown
- 1986-10-03 JP JP61234679A patent/JPS6287569A/ja active Granted
- 1986-10-06 NZ NZ217818A patent/NZ217818A/xx unknown
- 1986-10-08 SU SU864028251A patent/SU1443798A3/ru active
- 1986-10-08 CN CN86106848A patent/CN1015453B/zh not_active Expired
- 1986-10-09 IL IL80268A patent/IL80268A/xx not_active IP Right Cessation
- 1986-10-09 ZM ZM94/86A patent/ZM9486A1/xx unknown
- 1986-10-09 PT PT83506A patent/PT83506B/pt unknown
- 1986-10-09 PH PH34340A patent/PH22510A/en unknown
- 1986-10-09 EG EG231/86A patent/EG18126A/xx active
- 1986-10-09 ZA ZA867713A patent/ZA867713B/xx unknown
- 1986-10-10 IE IE267786A patent/IE59519B1/en not_active IP Right Cessation
- 1986-10-10 FI FI864099A patent/FI83642C/fi not_active IP Right Cessation
- 1986-10-10 TN TNTNSN86138A patent/TNSN86138A1/fr unknown
- 1986-10-10 NO NO864045A patent/NO168640C/no unknown
- 1986-10-10 AU AU63815/86A patent/AU583429B2/en not_active Expired
- 1986-10-10 ZW ZW203/86A patent/ZW20386A1/xx unknown
- 1986-10-10 DK DK198604868A patent/DK173954B1/da not_active IP Right Cessation
- 1986-10-10 HU HU864248A patent/HU196180B/hu unknown
- 1986-10-11 DZ DZ860211A patent/DZ997A1/fr active
-
1991
- 1991-06-18 SG SG46291A patent/SG46291G/en unknown
- 1991-07-11 HK HK524/91A patent/HK52491A/xx not_active IP Right Cessation
-
1992
- 1992-04-03 CY CY1603A patent/CY1603A/xx unknown
- 1992-11-27 LV LV920227A patent/LV5042A3/xx unknown
-
1993
- 1993-02-26 LT LTRP373A patent/LT2086B/xx not_active IP Right Cessation
- 1993-07-15 BG BG097952A patent/BG61320B2/bg unknown
-
1995
- 1995-10-30 NL NL950025C patent/NL950025I2/nl unknown
-
1996
- 1996-06-18 LV LV960189A patent/LV5767B4/xx unknown
- 1996-08-06 NO NO1996010C patent/NO1996010I1/no unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| EXP | Patent expired |