LT2086B - -difenil-4-aril-4-oksi-1-piperidinbutanamido-n-oksidu arba ju stereoizomeru gavimo budas - Google Patents

-difenil-4-aril-4-oksi-1-piperidinbutanamido-n-oksidu arba ju stereoizomeru gavimo budas

Info

Publication number
LT2086B
LT2086B LTRP373A LTRP373A LT2086B LT 2086 B LT2086 B LT 2086B LT RP373 A LTRP373 A LT RP373A LT RP373 A LTRP373 A LT RP373A LT 2086 B LT2086 B LT 2086B
Authority
LT
Lithuania
Prior art keywords
6alkyl
compounds
phenyl
hydrogen
independently
Prior art date
Application number
LTRP373A
Other languages
English (en)
Lithuanian (lt)
Inventor
Lourens Wals
Ludwig Paul Cooymans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LT2086B publication Critical patent/LT2086B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
LTRP373A 1985-10-11 1993-02-26 -difenil-4-aril-4-oksi-1-piperidinbutanamido-n-oksidu arba ju stereoizomeru gavimo budas LT2086B (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78656685A 1985-10-11 1985-10-11
SU864028251A SU1443798A3 (ru) 1985-10-11 1986-10-08 Способ получени @ , @ -дифенил-4-арил-4-окси-1-пиперидинбутанамид-N-оксидов или их стереоизомеров

Publications (1)

Publication Number Publication Date
LT2086B true LT2086B (lt) 1993-07-15

Family

ID=25138953

Family Applications (1)

Application Number Title Priority Date Filing Date
LTRP373A LT2086B (lt) 1985-10-11 1993-02-26 -difenil-4-aril-4-oksi-1-piperidinbutanamido-n-oksidu arba ju stereoizomeru gavimo budas

Country Status (33)

Country Link
EP (1) EP0219898B1 (nl)
JP (1) JPS6287569A (nl)
KR (1) KR940001772B1 (nl)
CN (1) CN1015453B (nl)
AT (1) ATE53022T1 (nl)
AU (1) AU583429B2 (nl)
BG (1) BG61320B2 (nl)
CA (1) CA1332236C (nl)
CY (1) CY1603A (nl)
DE (1) DE3671442D1 (nl)
DK (1) DK173954B1 (nl)
DZ (1) DZ997A1 (nl)
EG (1) EG18126A (nl)
ES (1) ES2002001A6 (nl)
FI (1) FI83642C (nl)
GR (1) GR862493B (nl)
HK (1) HK52491A (nl)
HU (1) HU196180B (nl)
IE (1) IE59519B1 (nl)
IL (1) IL80268A (nl)
LT (1) LT2086B (nl)
LV (2) LV5042A3 (nl)
NL (1) NL950025I2 (nl)
NO (2) NO168640C (nl)
NZ (1) NZ217818A (nl)
PH (1) PH22510A (nl)
PT (1) PT83506B (nl)
SG (1) SG46291G (nl)
SU (1) SU1443798A3 (nl)
TN (1) TNSN86138A1 (nl)
ZA (1) ZA867713B (nl)
ZM (1) ZM9486A1 (nl)
ZW (1) ZW20386A1 (nl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2088273C (en) * 1990-08-09 1996-05-14 Daniel Louis Barone Processes for formulating a solid oral dosage form of loperamide compounds
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
WO1997024325A1 (en) * 1995-12-28 1997-07-10 Takeda Chemical Industries, Ltd. DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS
AU3254499A (en) * 1998-03-06 1999-09-20 Janssen Pharmaceutica N.V. Glycine transport inhibitors
KR101315751B1 (ko) * 2011-05-30 2013-10-10 주식회사 엔지켐생명과학 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714159A (en) * 1971-03-30 1973-01-30 Janssen Pharmaceutica Nv 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
US4002618A (en) * 1976-02-23 1977-01-11 G. D. Searle & Co. 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles

Also Published As

Publication number Publication date
SG46291G (en) 1991-07-26
FI864099A (fi) 1987-04-12
EP0219898B1 (en) 1990-05-23
KR940001772B1 (ko) 1994-03-05
FI864099A0 (fi) 1986-10-10
IE862677L (en) 1987-04-11
HU196180B (en) 1988-10-28
IE59519B1 (en) 1994-03-09
ZA867713B (en) 1988-05-25
NO1996010I1 (no) 1996-08-06
ZM9486A1 (en) 1988-04-29
ZW20386A1 (en) 1988-05-11
KR870003986A (ko) 1987-05-06
PT83506A (en) 1986-11-01
FI83642C (fi) 1991-08-12
EG18126A (en) 1992-08-30
LV5042A3 (lv) 1993-06-10
JPS6287569A (ja) 1987-04-22
DK173954B1 (da) 2002-03-04
NZ217818A (en) 1989-03-29
DE3671442D1 (de) 1990-06-28
IL80268A0 (en) 1987-01-30
DZ997A1 (fr) 2004-09-13
CA1332236C (en) 1994-10-04
CY1603A (en) 1992-04-03
SU1443798A3 (ru) 1988-12-07
NO168640C (no) 1992-03-18
DK486886A (da) 1987-04-12
ATE53022T1 (de) 1990-06-15
PH22510A (en) 1988-09-12
HUT42444A (en) 1987-07-28
DK486886D0 (da) 1986-10-10
GR862493B (en) 1987-02-03
NL950025I2 (nl) 1997-03-03
ES2002001A6 (es) 1988-07-01
PT83506B (pt) 1989-02-28
AU6381586A (en) 1987-04-16
LV5767B4 (lv) 1997-06-20
HK52491A (en) 1991-07-19
AU583429B2 (en) 1989-04-27
FI83642B (fi) 1991-04-30
EP0219898A1 (en) 1987-04-29
TNSN86138A1 (fr) 1990-01-01
NO168640B (no) 1991-12-09
JPH0517909B2 (nl) 1993-03-10
NO864045D0 (no) 1986-10-10
BG61320B2 (bg) 1997-05-30
NL950025I1 (nl) 1996-01-02
CN86106848A (zh) 1987-04-08
IL80268A (en) 1991-03-10
CN1015453B (zh) 1992-02-12
LV5767A4 (lv) 1996-12-20
NO864045L (no) 1987-04-13

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LT2086B (lt) -difenil-4-aril-4-oksi-1-piperidinbutanamido-n-oksidu arba ju stereoizomeru gavimo budas
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Legal Events

Date Code Title Description
MM9A Lapsed patents

Effective date: 20011008