IL72123A - Substituted phenylalkyl piperazinyl-and homopiperazinylpropyl ureas and-thioureas,their preparation and pharmaceutical compositions containing them - Google Patents

Substituted phenylalkyl piperazinyl-and homopiperazinylpropyl ureas and-thioureas,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL72123A
IL72123A IL72123A IL7212384A IL72123A IL 72123 A IL72123 A IL 72123A IL 72123 A IL72123 A IL 72123A IL 7212384 A IL7212384 A IL 7212384A IL 72123 A IL72123 A IL 72123A
Authority
IL
Israel
Prior art keywords
homopiperazinylpropyl
thioureas
ureas
piperazinyl
preparation
Prior art date
Application number
IL72123A
Other languages
English (en)
Other versions
IL72123A0 (en
Original Assignee
Boehringer Ingelheim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd
Publication of IL72123A0 publication Critical patent/IL72123A0/xx
Publication of IL72123A publication Critical patent/IL72123A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL72123A 1983-06-16 1984-06-15 Substituted phenylalkyl piperazinyl-and homopiperazinylpropyl ureas and-thioureas,their preparation and pharmaceutical compositions containing them IL72123A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50483783A 1983-06-16 1983-06-16

Publications (2)

Publication Number Publication Date
IL72123A0 IL72123A0 (en) 1984-10-31
IL72123A true IL72123A (en) 1987-09-16

Family

ID=24007953

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72123A IL72123A (en) 1983-06-16 1984-06-15 Substituted phenylalkyl piperazinyl-and homopiperazinylpropyl ureas and-thioureas,their preparation and pharmaceutical compositions containing them

Country Status (25)

Country Link
EP (1) EP0129207B1 (es)
JP (1) JPS6075469A (es)
KR (1) KR890000175B1 (es)
AR (1) AR242377A1 (es)
AT (1) ATE33023T1 (es)
AU (1) AU565041B2 (es)
CA (1) CA1219260A (es)
CS (1) CS244821B2 (es)
DD (1) DD223710A5 (es)
DE (1) DE3469896D1 (es)
DK (1) DK160554C (es)
ES (3) ES533448A0 (es)
FI (1) FI76327C (es)
GR (1) GR82367B (es)
HU (1) HU192409B (es)
IE (1) IE59034B1 (es)
IL (1) IL72123A (es)
NO (1) NO161618C (es)
NZ (1) NZ208535A (es)
PH (1) PH24059A (es)
PL (2) PL146314B1 (es)
PT (1) PT78729B (es)
SU (2) SU1542415A3 (es)
YU (2) YU104584A (es)
ZA (1) ZA844527B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661481A (en) * 1983-06-16 1987-04-28 Boehringer Ingelheim Pharmaceuticals, Inc Substituted phenylalkylhomopiperazinylpropyl(ureas or thioureas) useful for treatment of immulogical, inflammatory and allergic disorders
FR2601366B1 (fr) * 1986-07-10 1988-11-25 Andre Buzas Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant.
JP2722250B2 (ja) * 1989-05-30 1998-03-04 興和株式会社 新規なジアミン化合物及びこれを含有する脳機能障害改善剤
JPH0525145A (ja) * 1991-07-15 1993-02-02 Mochida Pharmaceut Co Ltd アレルギー性疾患治療剤
JP3719612B2 (ja) * 1993-06-14 2005-11-24 塩野義製薬株式会社 ヘテロ環を含有する尿素誘導体
ITRM20060090A1 (it) * 2006-02-22 2007-08-23 Sigma Tau Ind Farmaceuti Nuovi composti inibitori cpt a livello del snc come farmaci antidiabetici e o antiobesita
TW201446748A (zh) 2007-08-22 2014-12-16 Astrazeneca Ab 環丙基醯胺衍生物
TW201039825A (en) * 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
EP2536702A4 (en) 2010-02-18 2013-07-10 Astrazeneca Ab NEW CRYSTALLINE FORM OF A CYCLOPROPYLBENZAMIDE DERIVATIVE
EP3484880B1 (en) 2016-07-13 2020-09-02 Leo Pharma A/S Heteroaromatic modulators of the retinoid-related orphan receptor gamma

Also Published As

Publication number Publication date
PH24059A (en) 1990-03-05
FI76327C (fi) 1988-10-10
ES537661A0 (es) 1985-11-01
PL252851A1 (en) 1986-07-01
NO161618C (no) 1989-09-06
PT78729B (en) 1986-10-21
ZA844527B (en) 1986-02-26
ES8506651A1 (es) 1985-08-01
DD223710A5 (de) 1985-06-19
FI842408A0 (fi) 1984-06-14
IL72123A0 (en) 1984-10-31
DK294084D0 (da) 1984-06-15
GR82367B (es) 1984-12-13
CA1219260A (en) 1987-03-17
JPS6075469A (ja) 1985-04-27
YU150186A (en) 1987-06-30
AU2940484A (en) 1984-12-20
EP0129207A3 (en) 1985-07-31
DK160554B (da) 1991-03-25
EP0129207B1 (en) 1988-03-16
NO842417L (no) 1984-12-17
PL248207A1 (en) 1985-08-13
SU1542415A3 (ru) 1990-02-07
PL146314B1 (en) 1989-01-31
NZ208535A (en) 1987-02-20
AU565041B2 (en) 1987-09-03
IE59034B1 (en) 1993-12-15
FI842408A (fi) 1984-12-17
IE841499L (en) 1984-12-16
ES537662A0 (es) 1985-09-16
ES8601928A1 (es) 1985-11-01
KR890000175B1 (ko) 1989-03-09
DK294084A (da) 1984-12-17
JPH0469147B2 (es) 1992-11-05
ES533448A0 (es) 1985-08-01
DK160554C (da) 1991-09-09
KR850000422A (ko) 1985-02-27
SU1387877A3 (ru) 1988-04-07
ES8600255A1 (es) 1985-09-16
YU104584A (en) 1986-12-31
DE3469896D1 (en) 1988-04-21
FI76327B (fi) 1988-06-30
EP0129207A2 (en) 1984-12-27
CS244821B2 (en) 1986-08-14
HUT34464A (en) 1985-03-28
NO161618B (no) 1989-05-29
PT78729A (en) 1984-07-01
PL147413B1 (en) 1989-05-31
HU192409B (en) 1987-06-29
ATE33023T1 (de) 1988-04-15
AR242377A1 (es) 1993-03-31

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Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees