IL55521A0 - 5-substituted-10,11-dihydtro-5h-dibenzo-(a,d)cyclohepten -5,10-imines - Google Patents

5-substituted-10,11-dihydtro-5h-dibenzo-(a,d)cyclohepten -5,10-imines

Info

Publication number
IL55521A0
IL55521A0 IL7855521A IL5552178A IL55521A0 IL 55521 A0 IL55521 A0 IL 55521A0 IL 7855521 A IL7855521 A IL 7855521A IL 5552178 A IL5552178 A IL 5552178A IL 55521 A0 IL55521 A0 IL 55521A0
Authority
IL
Israel
Prior art keywords
dihydtro
cyclohepten
dibenzo
imines
substituted
Prior art date
Application number
IL7855521A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IL55521A0 publication Critical patent/IL55521A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C07D295/116Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL7855521A 1977-09-19 1978-09-06 5-substituted-10,11-dihydtro-5h-dibenzo-(a,d)cyclohepten -5,10-imines IL55521A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83463977A 1977-09-19 1977-09-19

Publications (1)

Publication Number Publication Date
IL55521A0 true IL55521A0 (en) 1978-12-17

Family

ID=25267426

Family Applications (1)

Application Number Title Priority Date Filing Date
IL7855521A IL55521A0 (en) 1977-09-19 1978-09-06 5-substituted-10,11-dihydtro-5h-dibenzo-(a,d)cyclohepten -5,10-imines

Country Status (33)

Country Link
JP (1) JPS5463100A (ru)
AR (1) AR231544A1 (ru)
AT (1) AT370103B (ru)
AU (1) AU520178B2 (ru)
BE (1) BE870562A (ru)
CA (1) CA1129850A (ru)
CH (1) CH637954A5 (ru)
CY (1) CY1283A (ru)
DE (1) DE2840786A1 (ru)
DK (1) DK153843C (ru)
ES (7) ES473492A1 (ru)
FI (1) FI65618C (ru)
FR (1) FR2403334A1 (ru)
GB (2) GB2061947B (ru)
GR (1) GR65703B (ru)
HK (1) HK30885A (ru)
HU (1) HU180868B (ru)
IE (1) IE47355B1 (ru)
IL (1) IL55521A0 (ru)
IT (1) IT1113279B (ru)
KE (1) KE3501A (ru)
LU (1) LU80262A1 (ru)
NL (1) NL191488C (ru)
NO (1) NO151861C (ru)
NZ (1) NZ188361A (ru)
PH (1) PH15920A (ru)
PL (3) PL118478B1 (ru)
PT (1) PT68544A (ru)
SE (1) SE437520B (ru)
SG (1) SG9585G (ru)
SU (2) SU895288A3 (ru)
YU (1) YU41432B (ru)
ZA (1) ZA785291B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232158A (en) * 1979-06-04 1980-11-04 Merck & Co., Inc. 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines
US4477668A (en) * 1982-04-07 1984-10-16 Merck & Co., Inc. Process for 5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5,10-imine
GB8719199D0 (en) * 1987-08-13 1987-09-23 Merck Sharp & Dohme Chemical compounds
US5686614A (en) * 1995-04-11 1997-11-11 Neurogen Corporation Preparation of chiral 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imines by optical resolution
US5739337A (en) * 1996-03-08 1998-04-14 Neurogen Corporation Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo 3.2.1!octanes
US10583171B2 (en) 2015-11-30 2020-03-10 INSERM (Institut National de la Santé et de la Recherche Médicale) NMDAR antagonists for the treatment of diseases associated with angiogenesis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794904A (fr) * 1972-02-04 1973-08-02 Roussel Uclaf Nouveaux derives du dibenzocycloheptene et leur preparation
BE829075A (fr) * 1974-05-15 1975-11-14 9,10-dihydroanthracen-9,10-imines substituees et leurs analogues heterocycliques (aza)

Also Published As

Publication number Publication date
FI782680A (fi) 1979-03-20
GR65703B (en) 1980-10-22
AU3966878A (en) 1980-03-13
YU219678A (en) 1983-02-28
IE781866L (en) 1979-03-19
NZ188361A (en) 1982-06-29
ES483287A1 (es) 1980-04-16
YU41432B (en) 1987-06-30
HK30885A (en) 1985-04-26
PL121605B1 (en) 1982-05-31
NL7808847A (nl) 1979-03-21
SE7809187L (sv) 1979-03-20
NO151861C (no) 1985-06-19
PH15920A (en) 1983-04-22
ES483288A1 (es) 1980-04-16
GB2004872A (en) 1979-04-11
GB2061947B (en) 1982-08-04
SG9585G (en) 1985-08-08
FR2403334A1 (fr) 1979-04-13
DK389978A (da) 1979-03-20
IT1113279B (it) 1986-01-20
JPS5463100A (en) 1979-05-21
CA1129850A (en) 1982-08-17
ES473492A1 (es) 1980-07-16
PL118478B1 (en) 1981-10-31
SE437520B (sv) 1985-03-04
FI65618C (fi) 1984-06-11
SU915800A3 (en) 1982-03-23
FR2403334B1 (ru) 1982-11-19
CH637954A5 (de) 1983-08-31
ES483283A1 (es) 1980-04-16
SU895288A3 (ru) 1981-12-30
ES483286A1 (es) 1980-04-16
ZA785291B (en) 1980-04-30
IT7851126A0 (it) 1978-09-18
NO783017L (no) 1979-03-20
CY1283A (en) 1985-07-05
ATA669778A (de) 1982-07-15
ES483285A1 (es) 1980-09-01
DE2840786A1 (de) 1979-03-22
LU80262A1 (fr) 1979-06-01
AU520178B2 (en) 1982-01-21
NL191488B (nl) 1995-04-03
KE3501A (en) 1985-02-22
GB2004872B (en) 1982-04-15
FI65618B (fi) 1984-02-29
DE2840786C2 (ru) 1987-05-21
IE47355B1 (en) 1984-02-22
DK153843C (da) 1989-01-23
ES483284A1 (es) 1980-09-01
PL209632A1 (pl) 1979-06-04
BE870562A (fr) 1979-03-19
GB2061947A (en) 1981-05-20
NO151861B (no) 1985-03-11
AR231544A1 (es) 1984-12-28
PL112834B1 (en) 1980-11-29
JPS5639315B2 (ru) 1981-09-11
NL191488C (nl) 1995-08-04
PT68544A (en) 1978-10-01
DK153843B (da) 1988-09-12
AT370103B (de) 1983-03-10
HU180868B (en) 1983-04-29

Similar Documents

Publication Publication Date Title
ZA785001B (en) 1-phenyl-2-azolyl-4,4-dimethyl-1-penten-3-ols
CA43246S (en) A bottle
CS550778A2 (en) Usporadani pohonu pracovniho stolu obrabeciho stroje s podavacim a snimacim zarizenim upinacich desek
JPS5489508A (en) Special hand set
PH14778A (en) 4d,5d-epoxy 17b-hydroxy-4,17-dimethyl-3-oxo-androstane-2d-carbonitrile
CS526878A2 (en) Zpusob zpracovani pryzoveho odpadu,zejmena opotrebenych automobilovych pneumatik
AU4127478A (en) 6-oxygenated-3,2-dioxo-pregnane-derivatives
PH16029A (en) 2-deoxyfortimicin a,4-n-alkyl and 4-n-acyl-2-deoxyfortimicin b derivatives
IL55521A0 (en) 5-substituted-10,11-dihydtro-5h-dibenzo-(a,d)cyclohepten -5,10-imines
AU510159B2 (en) Lockable backon a sofabed
IE782180L (en) Structural member for vehicle¹body.
CS609378A2 (en) Plosny elektricky odpor s vysokou presnosti a nastavitelnosti ohmicke hodnoty, a zpusob nastavovani teto ohmicke hodnoty
CS909078A2 (en) Zpusob vyroby derivatu 9 aminopyrido (1,2 a)pyrimidinu
CS297778A1 (en) Zpusob fluidizacni upravy nesnadno tekoucich volne lozenych hmot a zarizeni k provadeni zpusobu
GB1542605A (en) 4-tertiary-amino-2,6-diaminopyridine-1-oxides
GB2001972B (en) Substituted 1-piperazinyl-triazolo-thieno-1,4-diazepines
IE45999L (en) 2-methoxybenzamides.
AU518288B2 (en) A. c. c. detector
CS375378A1 (en) Zpusob montaze nosnych dilcu uloznych skladovych konstrukci, zejmena skladovych regalu
IE780092L (en) Phenylazacycloalkanes.
IE782391L (en) Preparing a 4-carbalkoxyimidazoles
JPS5473109A (en) Acrotine a
BG25325A1 (en) A wc-tank
CS307677A2 (en) Zpusob vzorkovani s automatickou synchronizaci a zapojeni k provadeni tohoto zpusobu
BG25116A1 (en) A herbecide means

Legal Events

Date Code Title Description
RH Patent void