IL51998A - 7-chloro-3-alkoxycarbonyl-5-halophenyl-2-oxo-2,3-dihydro-1,4-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

7-chloro-3-alkoxycarbonyl-5-halophenyl-2-oxo-2,3-dihydro-1,4-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL51998A
IL51998A IL51998A IL5199877A IL51998A IL 51998 A IL51998 A IL 51998A IL 51998 A IL51998 A IL 51998A IL 5199877 A IL5199877 A IL 5199877A IL 51998 A IL51998 A IL 51998A
Authority
IL
Israel
Prior art keywords
halophenyl
alkoxycarbonyl
dihydro
oxo
chloro
Prior art date
Application number
IL51998A
Other languages
English (en)
Other versions
IL51998A0 (en
Original Assignee
Cm Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cm Ind filed Critical Cm Ind
Priority to IL58648A priority Critical patent/IL58648A/xx
Publication of IL51998A0 publication Critical patent/IL51998A0/xx
Publication of IL51998A publication Critical patent/IL51998A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL51998A 1976-05-05 1977-05-03 7-chloro-3-alkoxycarbonyl-5-halophenyl-2-oxo-2,3-dihydro-1,4-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them IL51998A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL58648A IL58648A (en) 1976-05-05 1977-05-03 Pharmaceutical compositions containing 7-chloro-3-ethoxy-carbonyl-5-halophenyl-2-oxo-2,3-dihydro-1,4-benzodiazepine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB18492/76A GB1538164A (en) 1976-05-05 1976-05-05 Benzodiazepine derivatives

Publications (2)

Publication Number Publication Date
IL51998A0 IL51998A0 (en) 1977-07-31
IL51998A true IL51998A (en) 1981-05-20

Family

ID=10113358

Family Applications (2)

Application Number Title Priority Date Filing Date
IL51998A IL51998A (en) 1976-05-05 1977-05-03 7-chloro-3-alkoxycarbonyl-5-halophenyl-2-oxo-2,3-dihydro-1,4-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL58648A IL58648A0 (en) 1976-05-05 1979-11-06 7-chloro-3-alkoxycarbonyl-5-haolophenyl-2-oxo-2,3-dihydro-1,4-benzo-diazepine derivatives their preparation and pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL58648A IL58648A0 (en) 1976-05-05 1979-11-06 7-chloro-3-alkoxycarbonyl-5-haolophenyl-2-oxo-2,3-dihydro-1,4-benzo-diazepine derivatives their preparation and pharmaceutical compositions containing them

Country Status (31)

Country Link
US (2) US4235897A (fr)
JP (3) JPS52156883A (fr)
AR (1) AR219924A1 (fr)
AT (1) AT356655B (fr)
AU (1) AU509147B2 (fr)
BE (1) BE854249A (fr)
CA (1) CA1083146A (fr)
CH (2) CH620912A5 (fr)
CS (3) CS207399B2 (fr)
DD (1) DD129446A5 (fr)
DE (2) DE2719608A1 (fr)
DK (2) DK195177A (fr)
EG (1) EG12724A (fr)
ES (1) ES458481A1 (fr)
FI (1) FI771413A (fr)
FR (2) FR2350346A1 (fr)
GB (1) GB1538164A (fr)
GR (1) GR63203B (fr)
HU (1) HU177573B (fr)
IE (1) IE44830B1 (fr)
IL (2) IL51998A (fr)
MX (1) MX4720E (fr)
NL (2) NL7704911A (fr)
NO (2) NO771560L (fr)
NZ (1) NZ184012A (fr)
PH (1) PH12641A (fr)
PT (1) PT66500B (fr)
SE (2) SE432099B (fr)
SU (1) SU888820A3 (fr)
YU (1) YU41818B (fr)
ZA (1) ZA772628B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2900017A1 (de) * 1978-01-10 1979-07-12 Clin Midy 3-alkoxycarbonyl-benzodiazepin- derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
FR2460938A1 (fr) * 1979-07-12 1981-01-30 Cm Ind Procede d'obtention de benzodiazepines-1,4
DE3021107A1 (de) * 1980-06-04 1981-12-17 Hoechst Ag, 6000 Frankfurt Carbamoyloxyamino-1,4-benzodiazepine, verfahren zu irer herstellung und diese enthaltende arzneimittel
JPS6038380A (ja) * 1983-08-11 1985-02-27 Shionogi & Co Ltd 1−ピペリジニル−1,4−ベンゾジアゼピン類の改良合成法
JPH04200396A (ja) * 1990-11-30 1992-07-21 Sanwa Kagaku Kenkyusho Co Ltd 過酸化水素の酵素学的高感度測定法及びそのための試薬
AU678503B2 (en) * 1993-09-24 1997-05-29 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds and their use as squalene synthetase inhibitors
KR100668045B1 (ko) * 2005-08-17 2007-01-16 한국과학기술연구원 ω-[2-(폴리알킬렌옥시)에틸티오]알킬알콕시실레인유도체와 이의 제조방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US28315A (en) * 1860-05-15 Improvement in method of decomposing fats into fatty acids and glycerine
US3136815A (en) * 1959-12-10 1964-06-09 Hoffmann La Roche Amino substituted benzophenone oximes and derivatives thereof
US3236838A (en) * 1964-06-09 1966-02-22 Hoffmann La Roche Certain 1-substituted-benzodiazepin-2-one compounds
FR1497456A (fr) * 1964-06-15 1967-10-13 Clin Byla Ets Ortho-amino aryl cétimines, composés hétérocycliques qui s'y rattachent et prépaation de ces divers corps
USRE28315E (en) 1964-06-15 1975-01-21 Cooc.hi
US3812103A (en) * 1967-04-11 1974-05-21 Hoffmann La Roche 2,3-dihydro-1,4-benzodiazepines
CH500997A (de) * 1967-08-09 1970-12-31 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH498846A (de) * 1967-08-09 1970-11-15 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
US3657223A (en) * 1969-01-17 1972-04-18 Hoffmann La Roche Process for the preparation of benzodiazepin-2-one derivatives
IL33961A (en) * 1969-03-13 1973-03-30 Sparamedica Ag Benzodiazepine aminoalkyl carboxylates,their preparation and pharmaceutical compositions containing them
US3718646A (en) * 1970-10-05 1973-02-27 Upjohn Co N-lower alkenyl-2,3-dihydro-2-oxo-5-phenyl-1h-1,4-benzodiazepine-1-carboxamides
IT1044223B (it) * 1972-08-09 1980-03-20 Zambeletti Spa L I propargil 1 4 benzodiazepine

Also Published As

Publication number Publication date
DE2719607C2 (fr) 1987-07-16
SE432099B (sv) 1984-03-19
FR2350345A1 (fr) 1977-12-02
AT356655B (de) 1980-05-12
CH620686A5 (fr) 1980-12-15
GB1538164A (en) 1979-01-10
US4587245A (en) 1986-05-06
FR2350346A1 (fr) 1977-12-02
FR2350346B1 (fr) 1980-11-21
DK195077A (da) 1977-11-06
AU2481377A (en) 1978-11-09
GR63203B (en) 1979-10-08
DE2719607A1 (de) 1977-11-17
AU509147B2 (en) 1980-04-24
CS207399B2 (en) 1981-07-31
JPS52156883A (en) 1977-12-27
AR219924A1 (es) 1980-09-30
JPS5711317B2 (fr) 1982-03-03
BE854249A (fr) 1977-11-04
US4235897A (en) 1980-11-25
JPS6137249B2 (fr) 1986-08-22
HU177573B (en) 1981-11-28
NO771560L (no) 1977-11-08
PT66500B (fr) 1978-10-13
CH620912A5 (fr) 1980-12-31
NL7704911A (nl) 1977-11-08
DK195177A (da) 1977-11-06
ATA320177A (de) 1979-10-15
JPS52156882A (en) 1977-12-27
NO813180L (no) 1977-11-08
DD129446A5 (de) 1978-01-18
PH12641A (en) 1979-07-11
DE2719608A1 (de) 1977-11-24
ZA772628B (en) 1978-03-29
PT66500A (fr) 1977-06-01
SE7705183L (sv) 1977-11-06
EG12724A (en) 1979-12-31
ES458481A1 (es) 1978-04-01
IL51998A0 (en) 1977-07-31
IE44830B1 (en) 1982-04-07
IE44830L (en) 1977-11-05
YU41818B (en) 1988-02-29
SE7705182L (sv) 1977-11-06
NZ184012A (en) 1981-11-19
CS207400B2 (en) 1981-07-31
NL7704912A (nl) 1977-11-08
YU113977A (en) 1982-08-31
MX4720E (es) 1982-08-13
SE431543B (sv) 1984-02-13
SU888820A3 (ru) 1981-12-07
NO149208C (no) 1984-03-07
FI771413A (fr) 1977-11-06
FR2350345B1 (fr) 1980-07-18
IL58648A0 (en) 1980-02-29
CS207398B2 (en) 1981-07-31
JPS5781472A (en) 1982-05-21
CA1083146A (fr) 1980-08-05
NO149208B (no) 1983-11-28

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