IL309517A - Methods, compounds and kits for amplifying test signals - Google Patents
Methods, compounds and kits for amplifying test signalsInfo
- Publication number
- IL309517A IL309517A IL309517A IL30951723A IL309517A IL 309517 A IL309517 A IL 309517A IL 309517 A IL309517 A IL 309517A IL 30951723 A IL30951723 A IL 30951723A IL 309517 A IL309517 A IL 309517A
- Authority
- IL
- Israel
- Prior art keywords
- reagent
- detectable label
- detectable
- signal amplification
- binding
- Prior art date
Links
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
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Landscapes
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| US4442204A (en) | 1981-04-10 | 1984-04-10 | Miles Laboratories, Inc. | Homogeneous specific binding assay device and preformed complex method |
| US5310687A (en) | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5591581A (en) | 1986-04-30 | 1997-01-07 | Igen, Inc. | Electrochemiluminescent rhenium moieties and methods for their use |
| US6316607B1 (en) | 1986-04-30 | 2001-11-13 | Igen International, Inc. | Electrochemiluminescent assays |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5786141A (en) | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
| US5679519A (en) * | 1995-05-09 | 1997-10-21 | Oprandy; John J. | Multi-label complex for enhanced sensitivity in electrochemiluminescence assay |
| US6136268A (en) | 1999-08-17 | 2000-10-24 | Orion Diagnostica | Method for luminescence measurements |
| US6808939B2 (en) | 2001-06-29 | 2004-10-26 | Igen International, Inc. | ECL labels having improved non-specific binding properties, methods of using and kits containing the same |
| JP2004534226A (ja) | 2001-06-29 | 2004-11-11 | メソ スケイル テクノロジーズ，エルエルシー | 発光試験測定用のアッセイプレート、リーダシステム及び方法 |
| EP1451348B1 (en) * | 2001-09-10 | 2015-08-12 | Meso Scale Technologies, LLC | Methods, reagents, kits and apparatus for protein function analysis |
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| CN103392181B (zh) | 2010-07-27 | 2018-04-27 | 梅索磅秤技术有限公司 | 消耗品数据管理 |
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| CN104822696B (zh) | 2012-08-02 | 2017-09-22 | 霍夫曼-拉罗奇有限公司 | 用于ecl的新型铱基配合物 |
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| EP4219750A3 (en) | 2013-03-11 | 2023-12-13 | Meso Scale Technologies, LLC. | Improved methods for conducting multiplexed assays |
| KR102257912B1 (ko) * | 2013-03-13 | 2021-05-27 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
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| EP3280520B1 (en) | 2015-04-06 | 2021-11-03 | Meso Scale Technologies, LLC | High throughput system for performing assays using electrochemiluminescence including a consumable shaking apparatus |
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