IL155813A0 - Benzodiazepine derivatives as gaba a receptor modulators - Google Patents
Benzodiazepine derivatives as gaba a receptor modulatorsInfo
- Publication number
- IL155813A0 IL155813A0 IL15581301A IL15581301A IL155813A0 IL 155813 A0 IL155813 A0 IL 155813A0 IL 15581301 A IL15581301 A IL 15581301A IL 15581301 A IL15581301 A IL 15581301A IL 155813 A0 IL155813 A0 IL 155813A0
- Authority
- IL
- Israel
- Prior art keywords
- gaba
- receptor modulators
- benzodiazepine derivatives
- benzodiazepine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00124332 | 2000-11-16 | ||
| PCT/EP2001/012887 WO2002040487A2 (en) | 2000-11-16 | 2001-11-08 | Benzodiazepine derivatives as gaba a receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL155813A0 true IL155813A0 (en) | 2003-12-23 |
Family
ID=8170315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15581301A IL155813A0 (en) | 2000-11-16 | 2001-11-08 | Benzodiazepine derivatives as gaba a receptor modulators |
Country Status (41)
| Country | Link |
|---|---|
| US (1) | US6743789B2 (xx) |
| EP (1) | EP1337535B1 (xx) |
| JP (1) | JP4088151B2 (xx) |
| KR (1) | KR100504300B1 (xx) |
| CN (1) | CN1191255C (xx) |
| AR (1) | AR031345A1 (xx) |
| AT (1) | ATE268776T1 (xx) |
| AU (2) | AU1700702A (xx) |
| BG (1) | BG107817A (xx) |
| BR (1) | BR0115393A (xx) |
| CA (1) | CA2427576C (xx) |
| CZ (1) | CZ295256B6 (xx) |
| DE (1) | DE60103776T2 (xx) |
| DK (1) | DK1337535T3 (xx) |
| EC (1) | ECSP034607A (xx) |
| ES (1) | ES2220831T3 (xx) |
| GC (1) | GC0000375A (xx) |
| GT (1) | GT200100230A (xx) |
| HK (1) | HK1062442A1 (xx) |
| HR (1) | HRP20030360A2 (xx) |
| HU (1) | HUP0303281A3 (xx) |
| IL (1) | IL155813A0 (xx) |
| JO (1) | JO2359B1 (xx) |
| MA (1) | MA26962A1 (xx) |
| MX (1) | MXPA03004251A (xx) |
| MY (1) | MY141675A (xx) |
| NO (1) | NO324706B1 (xx) |
| NZ (1) | NZ525413A (xx) |
| PA (1) | PA8532401A1 (xx) |
| PE (1) | PE20020583A1 (xx) |
| PL (1) | PL362925A1 (xx) |
| PT (1) | PT1337535E (xx) |
| RU (1) | RU2278865C2 (xx) |
| SI (1) | SI1337535T1 (xx) |
| SK (1) | SK7232003A3 (xx) |
| TR (1) | TR200402073T4 (xx) |
| TW (1) | TWI239333B (xx) |
| UY (1) | UY27026A1 (xx) |
| WO (1) | WO2002040487A2 (xx) |
| YU (1) | YU35603A (xx) |
| ZA (1) | ZA200303435B (xx) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6686352B2 (en) * | 2001-05-18 | 2004-02-03 | Hoffmann-La Roche Inc. | Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives |
| JP4616770B2 (ja) * | 2003-06-19 | 2011-01-19 | 第一三共株式会社 | 選択的なアミノ置換基導入法 |
| ES2515092T3 (es) | 2003-12-11 | 2014-10-29 | Sunovion Pharmaceuticals Inc. | Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión |
| CA2577060A1 (en) | 2004-08-13 | 2006-02-23 | Amgen Inc. | Substituted benzofused heterocycles |
| EP1809297B1 (en) * | 2004-10-12 | 2008-07-30 | F. Hoffmann-Roche AG | Imidazo[1,5a]triazolo[1,5d]benzodiazepine derivatives for the treatment of cognitive disorders |
| WO2006045430A1 (en) | 2004-10-20 | 2006-05-04 | F. Hoffmann-La Roche Ag | Imidazo-benzodiazepine derivatives |
| WO2006045429A1 (en) * | 2004-10-20 | 2006-05-04 | F. Hoffmann-La Roche Ag | Halogen substituted benzodiazepine derivatives |
| BRPI0515800A (pt) | 2004-12-14 | 2008-08-05 | Hoffmann La Roche | imidazo-benzodiazepinas tetracìclicas como moduladores de receptores de gaba |
| US8510055B2 (en) | 2005-08-03 | 2013-08-13 | The Johns Hopkins University | Methods for characterizing and treating cognitive impairment in aging and disease |
| WO2007019312A2 (en) * | 2005-08-03 | 2007-02-15 | The Johns Hopkins University | Methods for characterizing and treating cognitive impairment in aging and disease |
| CN101287738B (zh) * | 2005-10-11 | 2011-08-10 | 弗·哈夫曼-拉罗切有限公司 | 咪唑并苯并二氮杂*衍生物 |
| CA2625210A1 (en) * | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| WO2009139916A1 (en) * | 2008-05-16 | 2009-11-19 | Synta Pharmaceuticals Corp. | Tricyclic triazole compounds that modulate hsp90 activity |
| MX2011005119A (es) * | 2008-11-18 | 2011-05-30 | Hoffmann La Roche | Alquilciclohexileteres de dihidrotetraazabenzoazulenos. |
| NZ592076A (en) * | 2008-11-28 | 2012-06-29 | Hoffmann La Roche | Arylcyclohexylethers of dihydrotetraazabenzoazulenes for use as vasopressin via receptor antagonists |
| CU20090172A6 (es) | 2009-10-09 | 2011-10-05 | Facultad De Quimica Universidad De La Habana | Sistemas tricíclicos y tetracíclicos con actividad sobre el sistema nervioso central y vascular |
| WO2012068161A1 (en) | 2010-11-15 | 2012-05-24 | Agenebio, Inc. | Pyridazine derivatives, compositions and methods for treating cognitive impairment |
| US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
| EP2897963A4 (en) * | 2012-09-21 | 2016-03-30 | Uwm Res Foundation Inc | NOVEL GABAA AGONISTS AND METHODS OF USING THEM TO CONTROL BRONCHIC HYPER-REACTION AND INFLAMMATION DURING ASTHMA |
| EP3083569B1 (en) | 2013-12-20 | 2022-01-26 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| CN108026107B (zh) | 2015-06-19 | 2021-07-30 | 艾吉因生物股份有限公司 | 用于治疗认知损害的苯并二氮杂环庚三烯衍生物、组合物和方法 |
| US10059718B2 (en) * | 2016-01-04 | 2018-08-28 | Tabomedex Biosciences, LLC | Fused quadracyclic compounds, compositions and uses thereof |
| US10973479B2 (en) | 2016-05-16 | 2021-04-13 | Canon Medical Systems Corporation | X-ray diagnosis apparatus, X-ray diagnosis apparatus controlling method, and X-ray diagnosis system |
| BR112019012821A2 (pt) | 2016-12-19 | 2019-11-26 | Agenebio Inc | derivados de benzodiazepina, composições e métodos para o tratamento do comprometimento cognitivo |
| US20180170941A1 (en) * | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| KR102512548B1 (ko) | 2017-12-22 | 2023-03-22 | 삼성디스플레이 주식회사 | 유기 전계 발광 소자 및 유기 전계 발광 소자용 함질소 화합물 |
| CA3104478A1 (en) | 2018-06-19 | 2019-12-26 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| KR102151969B1 (ko) * | 2019-12-11 | 2020-09-04 | 주식회사 지투비 | 투과도 가변창의 제조방법 및 그에 의해 제조된 투과도 가변창 |
| CN112979658B (zh) * | 2021-02-22 | 2022-05-31 | 南湖实验室 | 一种氟马西尼的制备方法 |
| WO2024039886A1 (en) | 2022-08-19 | 2024-02-22 | Agenebio, Inc. | Benzazepine derivatives, compositions, and methods for treating cognitive impairment |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK174086D0 (da) | 1986-04-16 | 1986-04-16 | Ferrosan As | Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme |
| TW201311B (xx) * | 1991-06-17 | 1993-03-01 | Hoffmann La Roche |
-
2001
- 2001-11-07 TW TW090127658A patent/TWI239333B/zh not_active IP Right Cessation
- 2001-11-08 SI SI200130125T patent/SI1337535T1/xx unknown
- 2001-11-08 KR KR10-2003-7006609A patent/KR100504300B1/ko not_active IP Right Cessation
- 2001-11-08 AT AT01996541T patent/ATE268776T1/de not_active IP Right Cessation
- 2001-11-08 PL PL01362925A patent/PL362925A1/xx not_active Application Discontinuation
- 2001-11-08 SK SK723-2003A patent/SK7232003A3/sk unknown
- 2001-11-08 NZ NZ525413A patent/NZ525413A/en unknown
- 2001-11-08 YU YU35603A patent/YU35603A/sh unknown
- 2001-11-08 EP EP01996541A patent/EP1337535B1/en not_active Expired - Lifetime
- 2001-11-08 US US10/007,883 patent/US6743789B2/en not_active Expired - Fee Related
- 2001-11-08 DK DK01996541T patent/DK1337535T3/da active
- 2001-11-08 PT PT01996541T patent/PT1337535E/pt unknown
- 2001-11-08 TR TR2004/02073T patent/TR200402073T4/xx unknown
- 2001-11-08 HU HU0303281A patent/HUP0303281A3/hu unknown
- 2001-11-08 BR BR0115393-5A patent/BR0115393A/pt not_active IP Right Cessation
- 2001-11-08 JP JP2002543495A patent/JP4088151B2/ja not_active Expired - Fee Related
- 2001-11-08 CZ CZ20031597A patent/CZ295256B6/cs not_active IP Right Cessation
- 2001-11-08 CN CNB018189415A patent/CN1191255C/zh not_active Expired - Fee Related
- 2001-11-08 AU AU1700702A patent/AU1700702A/xx active Pending
- 2001-11-08 MX MXPA03004251A patent/MXPA03004251A/es active IP Right Grant
- 2001-11-08 IL IL15581301A patent/IL155813A0/xx unknown
- 2001-11-08 CA CA002427576A patent/CA2427576C/en not_active Expired - Fee Related
- 2001-11-08 WO PCT/EP2001/012887 patent/WO2002040487A2/en active IP Right Grant
- 2001-11-08 DE DE60103776T patent/DE60103776T2/de not_active Expired - Lifetime
- 2001-11-08 ES ES01996541T patent/ES2220831T3/es not_active Expired - Lifetime
- 2001-11-08 AU AU2002217007A patent/AU2002217007B2/en not_active Ceased
- 2001-11-08 RU RU2003116895/04A patent/RU2278865C2/ru not_active IP Right Cessation
- 2001-11-12 JO JO2001183A patent/JO2359B1/en active
- 2001-11-13 GC GCP20011724 patent/GC0000375A/en active
- 2001-11-14 PE PE2001001135A patent/PE20020583A1/es not_active Application Discontinuation
- 2001-11-15 UY UY27026A patent/UY27026A1/es not_active Application Discontinuation
- 2001-11-15 AR ARP010105323A patent/AR031345A1/es not_active Application Discontinuation
- 2001-11-15 GT GT200100230A patent/GT200100230A/es unknown
- 2001-11-15 MY MYPI20015253A patent/MY141675A/en unknown
- 2001-11-15 PA PA20018532401A patent/PA8532401A1/es unknown
-
2003
- 2003-05-05 ZA ZA200303435A patent/ZA200303435B/en unknown
- 2003-05-07 HR HR20030360A patent/HRP20030360A2/hr not_active Application Discontinuation
- 2003-05-15 NO NO20032208A patent/NO324706B1/no unknown
- 2003-05-15 EC EC2003004607A patent/ECSP034607A/es unknown
- 2003-05-16 BG BG107817A patent/BG107817A/bg unknown
- 2003-05-16 MA MA27163A patent/MA26962A1/fr unknown
-
2004
- 2004-07-21 HK HK04105348A patent/HK1062442A1/xx not_active IP Right Cessation
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