IL153930A0 - Novel indole derivatives and their use as medicaments - Google Patents

Novel indole derivatives and their use as medicaments

Info

Publication number
IL153930A0
IL153930A0 IL15393001A IL15393001A IL153930A0 IL 153930 A0 IL153930 A0 IL 153930A0 IL 15393001 A IL15393001 A IL 15393001A IL 15393001 A IL15393001 A IL 15393001A IL 153930 A0 IL153930 A0 IL 153930A0
Authority
IL
Israel
Prior art keywords
medicaments
indole derivatives
novel indole
novel
derivatives
Prior art date
Application number
IL15393001A
Other languages
English (en)
Original Assignee
Zentaris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Ag filed Critical Zentaris Ag
Publication of IL153930A0 publication Critical patent/IL153930A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IL15393001A 2000-07-28 2001-07-26 Novel indole derivatives and their use as medicaments IL153930A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10037310A DE10037310A1 (de) 2000-07-28 2000-07-28 Neue Indolderivate und deren Verwendung als Arzneimittel
PCT/EP2001/008644 WO2002010152A2 (de) 2000-07-28 2001-07-26 Neue indolderivate und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
IL153930A0 true IL153930A0 (en) 2003-07-31

Family

ID=7650860

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15393001A IL153930A0 (en) 2000-07-28 2001-07-26 Novel indole derivatives and their use as medicaments
IL153930A IL153930A (en) 2000-07-28 2003-01-14 History of indole, method of preparation and their use in the preparation of drugs

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL153930A IL153930A (en) 2000-07-28 2003-01-14 History of indole, method of preparation and their use in the preparation of drugs

Country Status (30)

Country Link
US (3) US7365081B2 (cs)
EP (3) EP1939195A1 (cs)
JP (1) JP5113973B2 (cs)
KR (1) KR100810453B1 (cs)
CN (1) CN1215066C (cs)
AR (1) AR055209A1 (cs)
AT (1) ATE392420T1 (cs)
AU (2) AU8975801A (cs)
BG (1) BG66457B1 (cs)
BR (1) BR0112807A (cs)
CA (3) CA2704691A1 (cs)
CY (1) CY1108770T1 (cs)
CZ (1) CZ304197B6 (cs)
DE (2) DE10037310A1 (cs)
DK (1) DK1309585T3 (cs)
ES (1) ES2303532T3 (cs)
HU (1) HU229254B1 (cs)
IL (2) IL153930A0 (cs)
MX (1) MXPA03000644A (cs)
NO (1) NO324594B1 (cs)
NZ (1) NZ524404A (cs)
PL (1) PL208673B1 (cs)
PT (1) PT1309585E (cs)
RU (1) RU2270196C9 (cs)
SI (1) SI1309585T1 (cs)
SK (1) SK288085B6 (cs)
TW (1) TWI291955B (cs)
UA (1) UA80670C2 (cs)
WO (1) WO2002010152A2 (cs)
ZA (1) ZA200300584B (cs)

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EP1484329A1 (de) * 2003-06-06 2004-12-08 Zentaris GmbH Indolderivate mit Apoptose induzierender Wirkung
US7205299B2 (en) * 2003-06-05 2007-04-17 Zentaris Gmbh Indole derivatives having an apoptosis-inducing effect
RU2327696C2 (ru) * 2003-06-05 2008-06-27 Центарис Гмбх Производные индола, обладающие индуцирующим апоптоз эффектом (варианты), фармацевтическая композиция на их основе
US7211588B2 (en) * 2003-07-25 2007-05-01 Zentaris Gmbh N-substituted indolyl-3-glyoxylamides, their use as medicaments and process for their preparation
US20050124623A1 (en) 2003-11-26 2005-06-09 Bender John A. Diazaindole-dicarbonyl-piperazinyl antiviral agents
US20060100432A1 (en) 2004-11-09 2006-05-11 Matiskella John D Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US7851476B2 (en) 2005-12-14 2010-12-14 Bristol-Myers Squibb Company Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
MX2009001327A (es) 2006-08-07 2009-06-05 Ironwood Pharmaceuticals Inc Compuestos de indol.
CA2724726C (en) 2008-05-23 2018-02-27 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein inhibitor
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen

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US6204261B1 (en) 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US3573294A (en) 1968-03-14 1971-03-30 Glaxo Lab Ltd 7 - (arylglyoxamido)cephalosporanic acids and their salts and alpha-carbonyl derivatives
US5192770A (en) 1990-12-07 1993-03-09 Syntex (U.S.A.) Inc. Serotonergic alpha-oxoacetamides
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
EP0775131A2 (de) * 1994-08-03 1997-05-28 ASTA Medica Aktiengesellschaft Indol-, indazol-, pyridopyrrol- und pyridopyrazol-derivate mit antiasthmatischer, antiallergischer, entzündungshemmender und immunmodulierender wirkung
US5732113A (en) 1996-06-20 1998-03-24 Stanford University Timing and frequency synchronization of OFDM signals
DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
US6514977B1 (en) 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors
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DE19814838C2 (de) * 1998-04-02 2001-01-18 Asta Medica Ag Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung
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WO1999055896A1 (en) 1998-04-27 1999-11-04 Aventis Pharma Deutschland Gmbh A new glucose-6-phosphate translocase inhibitor l 970885 from an actinomycete sp., and chemical derivatives thereof, a process for the preparation and their use as pharmaceuticals
TR200003130T2 (tr) 1998-04-28 2001-01-22 Arzneimittelwerk Dresden Gmbh Yeni hidroksiindoller, bunların fosfodiesteraz 4 inhibitörleri olarak kullanımları ve hazırlanmaları için işlemler
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WO2000031603A1 (de) * 1998-11-19 2000-06-02 Infineon Technologies Ag Schaltungsanordnung zum erzeugen einer stabilisierten versorgungsspannung für mehrere verbraucher
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US7205299B2 (en) * 2003-06-05 2007-04-17 Zentaris Gmbh Indole derivatives having an apoptosis-inducing effect
GB0525623D0 (en) 2005-12-16 2006-01-25 Hill Nicholas P R RFID reader
JP5241235B2 (ja) * 2007-02-28 2013-07-17 イビデン株式会社 ハニカム構造体の製造方法
WO2008105081A1 (ja) * 2007-02-28 2008-09-04 Ibiden Co., Ltd. ハニカムフィルタ
JPWO2008105082A1 (ja) * 2007-02-28 2010-06-03 イビデン株式会社 ハニカム構造体
WO2008126333A1 (ja) * 2007-03-30 2008-10-23 Ibiden Co., Ltd. ハニカム構造体
JPWO2008126335A1 (ja) * 2007-03-30 2010-07-22 イビデン株式会社 ハニカム構造体及びハニカム構造体の製造方法
WO2008126334A1 (ja) * 2007-03-30 2008-10-23 Ibiden Co., Ltd. ハニカム構造体の製造方法
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Also Published As

Publication number Publication date
US20080108819A1 (en) 2008-05-08
NZ524404A (en) 2004-08-27
DE10037310A1 (de) 2002-02-07
SK2222003A3 (en) 2004-04-06
AU2001289758B2 (en) 2006-07-06
US20030100597A1 (en) 2003-05-29
RU2270196C2 (ru) 2006-02-20
WO2002010152A2 (de) 2002-02-07
BG107560A (bg) 2003-10-31
CA2354210C (en) 2010-09-14
DK1309585T3 (da) 2008-06-23
DE50113867D1 (de) 2008-05-29
EP1309585A2 (de) 2003-05-14
US20080153875A1 (en) 2008-06-26
CN1215066C (zh) 2005-08-17
BG66457B1 (bg) 2014-10-31
ZA200300584B (en) 2003-07-18
EP1939195A1 (de) 2008-07-02
CA2704693A1 (en) 2002-01-28
EP2163552A1 (de) 2010-03-17
KR20030017658A (ko) 2003-03-03
PT1309585E (pt) 2008-06-09
WO2002010152A3 (de) 2002-08-01
SK288085B6 (sk) 2013-06-03
CY1108770T1 (el) 2014-04-09
RU2270196C9 (ru) 2007-11-27
US8008324B2 (en) 2011-08-30
HUP0300677A2 (hu) 2003-11-28
ATE392420T1 (de) 2008-05-15
KR100810453B1 (ko) 2008-03-07
EP1309585B1 (de) 2008-04-16
US7989453B2 (en) 2011-08-02
JP5113973B2 (ja) 2013-01-09
MXPA03000644A (es) 2003-06-06
ES2303532T3 (es) 2008-08-16
BR0112807A (pt) 2003-07-01
AU8975801A (en) 2002-02-13
NO20030382D0 (no) 2003-01-24
HK1058201A1 (en) 2004-05-07
SI1309585T1 (sl) 2008-08-31
PL208673B1 (pl) 2011-05-31
PL361356A1 (en) 2004-10-04
UA80670C2 (en) 2007-10-25
CA2354210A1 (en) 2002-01-28
AR055209A1 (es) 2007-08-15
NO20030382L (no) 2003-02-20
NO324594B1 (no) 2007-11-26
CA2704691A1 (en) 2002-01-28
JP2004505075A (ja) 2004-02-19
CN1447805A (zh) 2003-10-08
HU229254B1 (en) 2013-10-28
CZ304197B6 (cs) 2013-12-27
IL153930A (en) 2008-11-03
CZ2003500A3 (cs) 2004-03-17
TWI291955B (en) 2008-01-01
US7365081B2 (en) 2008-04-29

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