MXPA05013121A - Derivados de indol con efecto de induccion de apoptosis. - Google Patents
Derivados de indol con efecto de induccion de apoptosis.Info
- Publication number
- MXPA05013121A MXPA05013121A MXPA05013121A MXPA05013121A MXPA05013121A MX PA05013121 A MXPA05013121 A MX PA05013121A MX PA05013121 A MXPA05013121 A MX PA05013121A MX PA05013121 A MXPA05013121 A MX PA05013121A MX PA05013121 A MXPA05013121 A MX PA05013121A
- Authority
- MX
- Mexico
- Prior art keywords
- indole derivatives
- apoptosis
- inducing effect
- medicaments
- inducing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La invencion se refiere a derivados de indol usados como medicamentos para el tratamiento de enfermedades de tumor, de manera particular en el caso de resistencia de medicamentos contra otros ingredientes activos y carcinoma en metastasis.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47627703P | 2003-06-05 | 2003-06-05 | |
EP03012868A EP1484329A1 (de) | 2003-06-06 | 2003-06-06 | Indolderivate mit Apoptose induzierender Wirkung |
EP04011598A EP1595878A1 (de) | 2004-05-15 | 2004-05-15 | Indolderivate mit Apoptose induzierender Wirkung |
PCT/EP2004/005593 WO2004108702A1 (de) | 2003-06-05 | 2004-05-25 | Indolderivate mit apoptose induzierender wirkung |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05013121A true MXPA05013121A (es) | 2006-03-17 |
Family
ID=43661564
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05013121A MXPA05013121A (es) | 2003-06-05 | 2004-05-25 | Derivados de indol con efecto de induccion de apoptosis. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1641777A1 (es) |
JP (1) | JP4878285B2 (es) |
KR (1) | KR101132599B1 (es) |
CN (1) | CN1816543B (es) |
AU (1) | AU2004245198B2 (es) |
BR (1) | BRPI0410998A (es) |
CA (1) | CA2526663C (es) |
MX (1) | MXPA05013121A (es) |
NZ (1) | NZ543853A (es) |
RS (1) | RS20050901A (es) |
RU (1) | RU2327696C2 (es) |
WO (1) | WO2004108702A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8217042B2 (en) | 2005-11-11 | 2012-07-10 | Zentaris Gmbh | Pyridopyrazines and their use as modulators of kinases |
EP1790342A1 (de) | 2005-11-11 | 2007-05-30 | Zentaris GmbH | Pyridopyrazin-Derivate und deren Verwendung als Modulatoren der Signaltransduktionswege |
KR101400905B1 (ko) * | 2005-11-11 | 2014-05-29 | 아에테르나 젠타리스 게엠베하 | 신규한 피리도피라진 및 키나제의 조절제로서의 이의 용도 |
RU2448703C2 (ru) * | 2005-11-23 | 2012-04-27 | Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем | Онкогенное ras-специфичное цитотоксическое соединение и способы его применения |
NZ596024A (en) * | 2006-08-07 | 2013-07-26 | Ironwood Pharmaceuticals Inc | Indole compounds |
JP2010511041A (ja) * | 2006-11-28 | 2010-04-08 | ジオファーム オンコロジー, インコーポレイテッド | インジブリンを含むインドリル−3−グリオキシル酸誘導体の癌を処置するための単独またはさらなる薬剤との組み合わせでの使用 |
CN104958292B (zh) * | 2008-10-16 | 2018-10-16 | 阵列生物制药公司 | 用于在治疗中增加凋亡的有丝分裂抑制剂 |
WO2012017325A2 (en) * | 2010-07-19 | 2012-02-09 | Procaps Sa | Apparatus and process for encapsulating microparticles with liquid in soft gel capsules |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19814838C2 (de) * | 1998-04-02 | 2001-01-18 | Asta Medica Ag | Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung |
TWI269654B (en) * | 1999-09-28 | 2007-01-01 | Baxter Healthcare Sa | N-substituted indole-3-glyoxylamide compounds having anti-tumor action |
DE19962300A1 (de) * | 1999-12-23 | 2001-06-28 | Asta Medica Ag | Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung |
IT1318641B1 (it) * | 2000-07-25 | 2003-08-27 | Novuspharma Spa | Ammidi di acidi 2-(1h-indol-3-il)-2-oxo-acetici ad attivita'antitumorale. |
DE10037310A1 (de) * | 2000-07-28 | 2002-02-07 | Asta Medica Ag | Neue Indolderivate und deren Verwendung als Arzneimittel |
WO2003022280A2 (en) * | 2001-09-13 | 2003-03-20 | Synta Pharmaceuticals Corp. | 3-glyoxlylamideindoles for treating cancer |
-
2004
- 2004-05-25 CN CN2004800192716A patent/CN1816543B/zh not_active Expired - Fee Related
- 2004-05-25 NZ NZ543853A patent/NZ543853A/en not_active IP Right Cessation
- 2004-05-25 WO PCT/EP2004/005593 patent/WO2004108702A1/de active Application Filing
- 2004-05-25 RS YUP-2005/0901A patent/RS20050901A/sr unknown
- 2004-05-25 KR KR1020057023347A patent/KR101132599B1/ko not_active IP Right Cessation
- 2004-05-25 EP EP04734662A patent/EP1641777A1/de not_active Withdrawn
- 2004-05-25 MX MXPA05013121A patent/MXPA05013121A/es active IP Right Grant
- 2004-05-25 CA CA2526663A patent/CA2526663C/en not_active Expired - Fee Related
- 2004-05-25 RU RU2006100022/04A patent/RU2327696C2/ru not_active IP Right Cessation
- 2004-05-25 BR BRPI0410998-8A patent/BRPI0410998A/pt not_active IP Right Cessation
- 2004-05-25 JP JP2006508197A patent/JP4878285B2/ja not_active Expired - Fee Related
- 2004-05-25 AU AU2004245198A patent/AU2004245198B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
BRPI0410998A (pt) | 2006-07-04 |
KR101132599B1 (ko) | 2012-06-21 |
CN1816543A (zh) | 2006-08-09 |
RU2006100022A (ru) | 2006-05-27 |
JP2007523850A (ja) | 2007-08-23 |
AU2004245198B2 (en) | 2009-04-23 |
CA2526663C (en) | 2011-07-19 |
EP1641777A1 (de) | 2006-04-05 |
CA2526663A1 (en) | 2004-12-16 |
CN1816543B (zh) | 2011-01-19 |
NZ543853A (en) | 2009-09-25 |
AU2004245198A1 (en) | 2004-12-16 |
RS20050901A (en) | 2007-12-31 |
JP4878285B2 (ja) | 2012-02-15 |
KR20060034230A (ko) | 2006-04-21 |
WO2004108702A1 (de) | 2004-12-16 |
RU2327696C2 (ru) | 2008-06-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |