IL152325A0 - Bis-(n,n'-bis-(2-haloethyl)amino) phosphoramidates as antitumor agents - Google Patents
Bis-(n,n'-bis-(2-haloethyl)amino) phosphoramidates as antitumor agentsInfo
- Publication number
- IL152325A0 IL152325A0 IL15232501A IL15232501A IL152325A0 IL 152325 A0 IL152325 A0 IL 152325A0 IL 15232501 A IL15232501 A IL 15232501A IL 15232501 A IL15232501 A IL 15232501A IL 152325 A0 IL152325 A0 IL 152325A0
- Authority
- IL
- Israel
- Prior art keywords
- bis
- haloethyl
- phosphoramidates
- amino
- antitumor agents
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 150000008298 phosphoramidates Chemical class 0.000 title 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56318100A | 2000-05-02 | 2000-05-02 | |
| PCT/US2001/014290 WO2001083496A1 (en) | 2000-05-02 | 2001-05-02 | Bis-(n,n'-bis-(2-haloethyl)amino) phosphoramidates as antitumor agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL152325A0 true IL152325A0 (en) | 2003-05-29 |
Family
ID=24249433
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15232501A IL152325A0 (en) | 2000-05-02 | 2001-05-02 | Bis-(n,n'-bis-(2-haloethyl)amino) phosphoramidates as antitumor agents |
| IL152325A IL152325A (en) | 2000-05-02 | 2002-10-16 | Bite– (N, N'– Bite– (2-haloethyl) amino) phosphoramidates as antifungal agents |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL152325A IL152325A (en) | 2000-05-02 | 2002-10-16 | Bite– (N, N'– Bite– (2-haloethyl) amino) phosphoramidates as antifungal agents |
Country Status (26)
| Country | Link |
|---|---|
| EP (2) | EP1278759B1 (hu) |
| JP (1) | JP4249928B2 (hu) |
| KR (1) | KR100729980B1 (hu) |
| CN (1) | CN1182143C (hu) |
| AR (1) | AR029072A1 (hu) |
| AT (2) | ATE313549T1 (hu) |
| AU (2) | AU6115301A (hu) |
| BR (1) | BR0110553A (hu) |
| CA (1) | CA2407606C (hu) |
| CZ (1) | CZ20023615A3 (hu) |
| DE (2) | DE60116081T2 (hu) |
| DK (2) | DK1607399T3 (hu) |
| EA (1) | EA006852B1 (hu) |
| ES (2) | ES2253380T3 (hu) |
| HK (2) | HK1050368A1 (hu) |
| HU (1) | HUP0300688A3 (hu) |
| IL (2) | IL152325A0 (hu) |
| MX (1) | MXPA02010813A (hu) |
| NO (2) | NO328854B1 (hu) |
| NZ (1) | NZ522189A (hu) |
| PL (1) | PL207005B1 (hu) |
| PT (1) | PT1607399E (hu) |
| TW (1) | TWI308569B (hu) |
| UA (1) | UA74574C2 (hu) |
| WO (1) | WO2001083496A1 (hu) |
| ZA (1) | ZA200208591B (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200600091A (en) * | 2004-05-21 | 2006-01-01 | Telik Inc | Sulfonylethyl phosphorodiamidates |
| US8198247B2 (en) | 2004-12-21 | 2012-06-12 | Telik, Inc. | Process for and intermediates in the preparation of canfosfamide and its salts |
| US7655799B2 (en) | 2006-11-29 | 2010-02-02 | Telik, Inc. | 2{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N,N',N'-tetrakis(2-chloroethyl)phosphorodiamidates |
| US7872134B2 (en) | 2007-12-12 | 2011-01-18 | Telik, Inc. | 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates |
| JP2011517555A (ja) * | 2008-03-14 | 2011-06-16 | ジェネンテック， インコーポレイテッド | 薬剤耐性に関連する遺伝的変異 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5556942A (en) * | 1991-04-29 | 1996-09-17 | Terrapin Technologies, Inc. | Glutathione S-transferase-activated compounds |
-
2001
- 2001-02-05 UA UA2002119554A patent/UA74574C2/uk unknown
- 2001-05-01 TW TW090110381A patent/TWI308569B/zh not_active IP Right Cessation
- 2001-05-02 PT PT05020467T patent/PT1607399E/pt unknown
- 2001-05-02 DK DK05020467.6T patent/DK1607399T3/da active
- 2001-05-02 EP EP01935025A patent/EP1278759B1/en not_active Expired - Lifetime
- 2001-05-02 JP JP2001580921A patent/JP4249928B2/ja not_active Expired - Fee Related
- 2001-05-02 DE DE60116081T patent/DE60116081T2/de not_active Expired - Lifetime
- 2001-05-02 AR ARP010102067A patent/AR029072A1/es active IP Right Grant
- 2001-05-02 AU AU6115301A patent/AU6115301A/xx active Pending
- 2001-05-02 EP EP05020467A patent/EP1607399B1/en not_active Expired - Lifetime
- 2001-05-02 DK DK01935025T patent/DK1278759T3/da active
- 2001-05-02 PL PL358155A patent/PL207005B1/pl not_active IP Right Cessation
- 2001-05-02 HU HU0300688A patent/HUP0300688A3/hu unknown
- 2001-05-02 EA EA200201154A patent/EA006852B1/ru not_active IP Right Cessation
- 2001-05-02 CA CA002407606A patent/CA2407606C/en not_active Expired - Fee Related
- 2001-05-02 MX MXPA02010813A patent/MXPA02010813A/es active IP Right Grant
- 2001-05-02 ES ES01935025T patent/ES2253380T3/es not_active Expired - Lifetime
- 2001-05-02 AU AU2001261153A patent/AU2001261153B2/en not_active Ceased
- 2001-05-02 CN CNB018089623A patent/CN1182143C/zh not_active Expired - Fee Related
- 2001-05-02 KR KR1020027014577A patent/KR100729980B1/ko not_active IP Right Cessation
- 2001-05-02 AT AT01935025T patent/ATE313549T1/de active
- 2001-05-02 IL IL15232501A patent/IL152325A0/xx unknown
- 2001-05-02 DE DE60141181T patent/DE60141181D1/de not_active Expired - Lifetime
- 2001-05-02 BR BR0110553-1A patent/BR0110553A/pt active Search and Examination
- 2001-05-02 ES ES05020467T patent/ES2337154T3/es not_active Expired - Lifetime
- 2001-05-02 AT AT05020467T patent/ATE455779T1/de active
- 2001-05-02 CZ CZ20023615A patent/CZ20023615A3/cs unknown
- 2001-05-02 WO PCT/US2001/014290 patent/WO2001083496A1/en active IP Right Grant
- 2001-05-02 NZ NZ522189A patent/NZ522189A/en not_active IP Right Cessation
-
2002
- 2002-10-16 IL IL152325A patent/IL152325A/en not_active IP Right Cessation
- 2002-10-23 ZA ZA200208591A patent/ZA200208591B/en unknown
- 2002-11-01 NO NO20025240A patent/NO328854B1/no not_active IP Right Cessation
-
2003
- 2003-03-31 HK HK03102283A patent/HK1050368A1/xx not_active IP Right Cessation
-
2006
- 2006-04-04 HK HK06104167.3A patent/HK1084119A1/xx not_active IP Right Cessation
-
2009
- 2009-11-18 NO NO20093371A patent/NO331833B1/no not_active IP Right Cessation
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