IL147069A0 - Novel benzene derivatives, a process for their preparation and pharmaceutical compositions containing them - Google Patents

Novel benzene derivatives, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL147069A0
IL147069A0 IL14706900A IL14706900A IL147069A0 IL 147069 A0 IL147069 A0 IL 147069A0 IL 14706900 A IL14706900 A IL 14706900A IL 14706900 A IL14706900 A IL 14706900A IL 147069 A0 IL147069 A0 IL 147069A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
benzene derivatives
novel benzene
Prior art date
Application number
IL14706900A
Other languages
English (en)
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of IL147069A0 publication Critical patent/IL147069A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
IL14706900A 1999-07-02 2000-06-27 Novel benzene derivatives, a process for their preparation and pharmaceutical compositions containing them IL147069A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9908532A FR2795724B1 (fr) 1999-07-02 1999-07-02 Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant
PCT/FR2000/001790 WO2001002380A1 (fr) 1999-07-02 2000-06-27 N-aralkyl amines cycliques antipsychotiques

Publications (1)

Publication Number Publication Date
IL147069A0 true IL147069A0 (en) 2002-08-14

Family

ID=9547628

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14706900A IL147069A0 (en) 1999-07-02 2000-06-27 Novel benzene derivatives, a process for their preparation and pharmaceutical compositions containing them
IL147069A IL147069A (en) 1999-07-02 2001-12-12 Benzene derivatives, a process for their preparation and pharmaceutical compounds containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL147069A IL147069A (en) 1999-07-02 2001-12-12 Benzene derivatives, a process for their preparation and pharmaceutical compounds containing them

Country Status (31)

Country Link
US (1) US6908914B1 (bs)
EP (1) EP1196403B1 (bs)
JP (1) JP4931309B2 (bs)
KR (1) KR100760446B1 (bs)
CN (1) CN1156462C (bs)
AR (1) AR029374A1 (bs)
AT (1) ATE309231T1 (bs)
AU (1) AU778299B2 (bs)
BG (1) BG65209B1 (bs)
BR (1) BR0012463B1 (bs)
CA (1) CA2376691C (bs)
CO (1) CO5021196A1 (bs)
CZ (1) CZ300936B6 (bs)
DE (1) DE60023898T2 (bs)
DK (1) DK1196403T3 (bs)
EA (1) EA004048B1 (bs)
ES (1) ES2250160T3 (bs)
FR (1) FR2795724B1 (bs)
HK (1) HK1043122A1 (bs)
HR (1) HRP20010949B1 (bs)
HU (1) HU228983B1 (bs)
IL (2) IL147069A0 (bs)
ME (1) MEP25508A (bs)
MX (1) MXPA01013207A (bs)
NO (1) NO322230B1 (bs)
NZ (1) NZ516342A (bs)
RS (1) RS50266B (bs)
TW (1) TWI285640B (bs)
UA (1) UA71009C2 (bs)
WO (1) WO2001002380A1 (bs)
ZA (1) ZA200200018B (bs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003017764A1 (de) * 2001-08-23 2003-03-06 Bayer Cropscience S.A. Substituierte propargylamine
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790971A (fr) * 1971-11-09 1973-05-07 Janssen Pharmaceutica Nv Metode ter voorkoming van patologische reakties die de funktie van het komplement vereisen
JPS504086A (bs) * 1973-01-18 1975-01-16
US4104383A (en) * 1973-11-02 1978-08-01 C M Industries Derivatives of phenylpropenylamine
GB1475314A (en) * 1973-11-02 1977-06-01 Cm Ind Phenyl-propylamine derivatives
US4855462A (en) * 1988-06-17 1989-08-08 Pennwalt Corporation Antihistamines
EP0347123A3 (en) * 1988-06-17 1991-07-03 Fisons Corporation Dibenzo-cycloheptenyl, -cycloheptyl and -oxepinyl amines having antihistaminic properties
US4912222A (en) * 1988-06-17 1990-03-27 Fisons Corporation Antihistamines related to cyproheptadine
FR2663328B1 (fr) * 1990-06-14 1994-08-05 Sanofi Sa Derives d'hexahydroazepines, un procede pour leur preparation et compositions pharmaceutiques les contenant.
WO1993000313A2 (en) * 1991-06-27 1993-01-07 Virginia Commonwealth University Sigma receptor ligands and the use thereof
JP3199405B2 (ja) * 1991-08-30 2001-08-20 生化学工業株式会社 肝細胞球状集塊化剤及び球状集塊化肝細胞の製造方法
US5486517A (en) * 1994-05-10 1996-01-23 Warner-Lambert Company Benzimidazoles and imidazopyridines as central nervous system agents
FR2751645B1 (fr) * 1996-07-29 1998-12-24 Sanofi Sa Amines pour la fabrication de medicaments destines a empecher la proliferation de cellules tumorales
TR199902283T2 (xx) * 1997-03-18 1999-12-21 Smithkline Beecham P.L.C. �kame edilmi� izokuinolin t�revleri ve bunlar�n antikonvulsant olarak kullan�m�.

Also Published As

Publication number Publication date
HU228983B1 (en) 2013-07-29
FR2795724B1 (fr) 2002-12-13
PL356186A1 (en) 2004-06-14
CA2376691A1 (en) 2001-01-11
BR0012463A (pt) 2002-04-02
HUP0202200A2 (en) 2002-10-28
EA004048B1 (ru) 2003-12-25
CO5021196A1 (es) 2001-03-27
CN1367783A (zh) 2002-09-04
CN1156462C (zh) 2004-07-07
AR029374A1 (es) 2003-06-25
WO2001002380A8 (fr) 2001-06-28
BG65209B1 (bg) 2007-07-31
MEP25508A (bs) 2010-06-10
US6908914B1 (en) 2005-06-21
BG106255A (en) 2002-10-31
CA2376691C (en) 2009-09-01
TWI285640B (en) 2007-08-21
KR20020016877A (ko) 2002-03-06
DE60023898T2 (de) 2006-08-10
NO20016392L (no) 2002-03-04
NZ516342A (en) 2003-08-29
CZ300936B6 (cs) 2009-09-16
FR2795724A1 (fr) 2001-01-05
HUP0202200A3 (en) 2002-12-28
HK1043122A1 (zh) 2002-09-06
UA71009C2 (uk) 2004-11-15
DE60023898D1 (de) 2005-12-15
EA200101209A1 (ru) 2002-06-27
RS50266B (sr) 2009-07-15
NO322230B1 (no) 2006-08-28
JP4931309B2 (ja) 2012-05-16
WO2001002380A1 (fr) 2001-01-11
EP1196403B1 (fr) 2005-11-09
HRP20010949A2 (en) 2003-04-30
ZA200200018B (en) 2003-01-02
KR100760446B1 (ko) 2007-10-04
ES2250160T3 (es) 2006-04-16
ATE309231T1 (de) 2005-11-15
EP1196403A1 (fr) 2002-04-17
AU778299B2 (en) 2004-11-25
BR0012463B1 (pt) 2014-11-04
CZ20014697A3 (cs) 2002-04-17
AU5992400A (en) 2001-01-22
YU91101A (sh) 2004-09-03
MXPA01013207A (es) 2002-06-21
IL147069A (en) 2006-09-05
NO20016392D0 (no) 2001-12-27
JP2003503487A (ja) 2003-01-28
DK1196403T3 (da) 2006-03-20
HRP20010949B1 (en) 2006-06-30

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Legal Events

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FF Patent granted