MEP25508A - Antipsihotični ciklični n-aralkil amini - Google Patents
Antipsihotični ciklični n-aralkil aminiInfo
- Publication number
- MEP25508A MEP25508A MEP-255/08A MEP25508A MEP25508A ME P25508 A MEP25508 A ME P25508A ME P25508 A MEP25508 A ME P25508A ME P25508 A MEP25508 A ME P25508A
- Authority
- ME
- Montenegro
- Prior art keywords
- chlorine
- hydrogen
- compounds
- fluorine atom
- aralkyl amines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Pronalazak se odnosi na jedinjenja formule (I), gdje A, pretstavlja grupu koja se bira između sljedećih grupa: -C=C-, -CH=CH-; CH2-CH2-; n je jednako 1 ili 2; X pretstavlja atom vodonika, hlora ili fluora, metil ili metoksi grupu; Y pretstavlja atom vodonika, hlora ili fluora; R1 pretstavlja cikloheksil, fenil, cikloheptil, tercijarni butil, diciklopropilmetil, biciklo[3.2.1]oktaniI, 4-tetrahidropiranil, 4-tetrahidrotiopiranil ili adamantil grupu; R2 i R3 grade zajedno sa atomom azota na koji su vezani ciklični amin; i na adicione soli pomenutih jedinjenja sa farmaceutski prihvatljivim kisjelinama, isto kao i na njihove solvate i hidrate.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9908532A FR2795724B1 (fr) | 1999-07-02 | 1999-07-02 | Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
PCT/FR2000/001790 WO2001002380A1 (fr) | 1999-07-02 | 2000-06-27 | N-aralkyl amines cycliques antipsychotiques |
Publications (1)
Publication Number | Publication Date |
---|---|
MEP25508A true MEP25508A (bs) | 2010-06-10 |
Family
ID=9547628
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-255/08A MEP25508A (bs) | 1999-07-02 | 2000-06-27 | Antipsihotični ciklični n-aralkil amini |
Country Status (31)
Country | Link |
---|---|
US (1) | US6908914B1 (bs) |
EP (1) | EP1196403B1 (bs) |
JP (1) | JP4931309B2 (bs) |
KR (1) | KR100760446B1 (bs) |
CN (1) | CN1156462C (bs) |
AR (1) | AR029374A1 (bs) |
AT (1) | ATE309231T1 (bs) |
AU (1) | AU778299B2 (bs) |
BG (1) | BG65209B1 (bs) |
BR (1) | BR0012463B1 (bs) |
CA (1) | CA2376691C (bs) |
CO (1) | CO5021196A1 (bs) |
CZ (1) | CZ300936B6 (bs) |
DE (1) | DE60023898T2 (bs) |
DK (1) | DK1196403T3 (bs) |
EA (1) | EA004048B1 (bs) |
ES (1) | ES2250160T3 (bs) |
FR (1) | FR2795724B1 (bs) |
HK (1) | HK1043122A1 (bs) |
HR (1) | HRP20010949B1 (bs) |
HU (1) | HU228983B1 (bs) |
IL (2) | IL147069A0 (bs) |
ME (1) | MEP25508A (bs) |
MX (1) | MXPA01013207A (bs) |
NO (1) | NO322230B1 (bs) |
NZ (1) | NZ516342A (bs) |
RS (1) | RS50266B (bs) |
TW (1) | TWI285640B (bs) |
UA (1) | UA71009C2 (bs) |
WO (1) | WO2001002380A1 (bs) |
ZA (1) | ZA200200018B (bs) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1420644B1 (de) * | 2001-08-23 | 2006-05-31 | Bayer CropScience S.A. | Substituierte propargylamine |
AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
EP2026813A2 (en) | 2006-05-09 | 2009-02-25 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE790971A (fr) * | 1971-11-09 | 1973-05-07 | Janssen Pharmaceutica Nv | Metode ter voorkoming van patologische reakties die de funktie van het komplement vereisen |
JPS504086A (bs) * | 1973-01-18 | 1975-01-16 | ||
GB1475314A (en) * | 1973-11-02 | 1977-06-01 | Cm Ind | Phenyl-propylamine derivatives |
US4104383A (en) * | 1973-11-02 | 1978-08-01 | C M Industries | Derivatives of phenylpropenylamine |
US4912222A (en) * | 1988-06-17 | 1990-03-27 | Fisons Corporation | Antihistamines related to cyproheptadine |
EP0347123A3 (en) * | 1988-06-17 | 1991-07-03 | Fisons Corporation | Dibenzo-cycloheptenyl, -cycloheptyl and -oxepinyl amines having antihistaminic properties |
US4855462A (en) * | 1988-06-17 | 1989-08-08 | Pennwalt Corporation | Antihistamines |
FR2663328B1 (fr) | 1990-06-14 | 1994-08-05 | Sanofi Sa | Derives d'hexahydroazepines, un procede pour leur preparation et compositions pharmaceutiques les contenant. |
WO1993000313A2 (en) * | 1991-06-27 | 1993-01-07 | Virginia Commonwealth University | Sigma receptor ligands and the use thereof |
JP3199405B2 (ja) * | 1991-08-30 | 2001-08-20 | 生化学工業株式会社 | 肝細胞球状集塊化剤及び球状集塊化肝細胞の製造方法 |
US5486517A (en) * | 1994-05-10 | 1996-01-23 | Warner-Lambert Company | Benzimidazoles and imidazopyridines as central nervous system agents |
FR2751645B1 (fr) * | 1996-07-29 | 1998-12-24 | Sanofi Sa | Amines pour la fabrication de medicaments destines a empecher la proliferation de cellules tumorales |
JP3690423B2 (ja) * | 1997-03-18 | 2005-08-31 | スミスクライン ビーチャム パブリック リミテッド カンパニー | 置換イソキノリン誘導体およびその抗痙攣薬としての使用 |
-
1999
- 1999-07-02 FR FR9908532A patent/FR2795724B1/fr not_active Expired - Fee Related
-
2000
- 2000-06-27 ES ES00946022T patent/ES2250160T3/es not_active Expired - Lifetime
- 2000-06-27 RS YU91101A patent/RS50266B/sr unknown
- 2000-06-27 NZ NZ516342A patent/NZ516342A/en not_active IP Right Cessation
- 2000-06-27 UA UA2001128823A patent/UA71009C2/uk unknown
- 2000-06-27 CZ CZ20014697A patent/CZ300936B6/cs not_active IP Right Cessation
- 2000-06-27 EP EP00946022A patent/EP1196403B1/fr not_active Expired - Lifetime
- 2000-06-27 EA EA200101209A patent/EA004048B1/ru not_active IP Right Cessation
- 2000-06-27 US US10/019,205 patent/US6908914B1/en not_active Expired - Lifetime
- 2000-06-27 HU HU0202200A patent/HU228983B1/hu not_active IP Right Cessation
- 2000-06-27 BR BRPI0012463-0A patent/BR0012463B1/pt not_active IP Right Cessation
- 2000-06-27 MX MXPA01013207A patent/MXPA01013207A/es active IP Right Grant
- 2000-06-27 KR KR1020017016966A patent/KR100760446B1/ko not_active IP Right Cessation
- 2000-06-27 DK DK00946022T patent/DK1196403T3/da active
- 2000-06-27 IL IL14706900A patent/IL147069A0/xx active IP Right Grant
- 2000-06-27 ME MEP-255/08A patent/MEP25508A/bs unknown
- 2000-06-27 CN CNB008111413A patent/CN1156462C/zh not_active Expired - Fee Related
- 2000-06-27 JP JP2001507818A patent/JP4931309B2/ja not_active Expired - Fee Related
- 2000-06-27 TW TW089112618A patent/TWI285640B/zh not_active IP Right Cessation
- 2000-06-27 WO PCT/FR2000/001790 patent/WO2001002380A1/fr active IP Right Grant
- 2000-06-27 CA CA002376691A patent/CA2376691C/en not_active Expired - Fee Related
- 2000-06-27 AU AU59924/00A patent/AU778299B2/en not_active Ceased
- 2000-06-27 DE DE60023898T patent/DE60023898T2/de not_active Expired - Lifetime
- 2000-06-27 AT AT00946022T patent/ATE309231T1/de active
- 2000-06-28 CO CO00048530A patent/CO5021196A1/es unknown
- 2000-06-30 AR ARP000103334A patent/AR029374A1/es active IP Right Grant
-
2001
- 2001-12-12 IL IL147069A patent/IL147069A/en not_active IP Right Cessation
- 2001-12-20 BG BG106255A patent/BG65209B1/bg unknown
- 2001-12-21 HR HR20010949A patent/HRP20010949B1/xx not_active IP Right Cessation
- 2001-12-27 NO NO20016392A patent/NO322230B1/no not_active IP Right Cessation
-
2002
- 2002-01-02 ZA ZA200200018A patent/ZA200200018B/en unknown
- 2002-06-24 HK HK02104681.4A patent/HK1043122A1/zh unknown
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