IL144988A0 - Nasal delivery device - Google Patents

Nasal delivery device

Info

Publication number
IL144988A0
IL144988A0 IL14498800A IL14498800A IL144988A0 IL 144988 A0 IL144988 A0 IL 144988A0 IL 14498800 A IL14498800 A IL 14498800A IL 14498800 A IL14498800 A IL 14498800A IL 144988 A0 IL144988 A0 IL 144988A0
Authority
IL
Israel
Prior art keywords
subject
nostril
substance
gas flow
delivery unit
Prior art date
Application number
IL14498800A
Other languages
English (en)
Original Assignee
Optinose As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26315212&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL144988(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9904906.6A external-priority patent/GB9904906D0/en
Priority claimed from GBGB9911686.5A external-priority patent/GB9911686D0/en
Application filed by Optinose As filed Critical Optinose As
Publication of IL144988A0 publication Critical patent/IL144988A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0018Details of inhalators; Constructional features thereof with exhalation check valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0098Activated by exhalation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/08Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0866Passive resistors therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • A61M3/0233Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/105Filters
    • A61M16/1055Filters bacterial
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/105Filters
    • A61M16/106Filters in a path
    • A61M16/1065Filters in a path in the expiratory path
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0468Liquids non-physiological
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/43General characteristics of the apparatus making noise when used correctly
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/59Aesthetic features, e.g. distraction means to prevent fears of child patients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/14Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0618Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0625Mouth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • A61M3/0202Enemata; Irrigators with electronic control means or interfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • A61M3/0279Cannula; Nozzles; Tips; their connection means
IL14498800A 1999-03-03 2000-03-03 Nasal delivery device IL144988A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9904906.6A GB9904906D0 (en) 1999-03-03 1999-03-03 Device
GBGB9911686.5A GB9911686D0 (en) 1999-05-19 1999-05-19 Device
PCT/IB2000/000273 WO2000051672A1 (en) 1999-03-03 2000-03-03 Nasal delivery device

Publications (1)

Publication Number Publication Date
IL144988A0 true IL144988A0 (en) 2002-06-30

Family

ID=26315212

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14498800A IL144988A0 (en) 1999-03-03 2000-03-03 Nasal delivery device
IL144988A IL144988A (en) 1999-03-03 2001-08-20 A device that transfers material to the nose

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL144988A IL144988A (en) 1999-03-03 2001-08-20 A device that transfers material to the nose

Country Status (25)

Country Link
US (8) US6715485B1 (es)
EP (6) EP1555038B1 (es)
JP (2) JP4543553B2 (es)
KR (1) KR100692422B1 (es)
CN (2) CN1217712C (es)
AT (3) ATE285810T1 (es)
AU (1) AU766410B2 (es)
BR (1) BR0008650B1 (es)
CA (1) CA2364009C (es)
CY (1) CY1111201T1 (es)
DE (2) DE60017099T2 (es)
DK (3) DK1161274T3 (es)
ES (3) ES2235836T3 (es)
GB (1) GB2349092B (es)
HK (2) HK1039459B (es)
ID (1) ID30286A (es)
IL (2) IL144988A0 (es)
MX (1) MXPA01008849A (es)
NO (1) NO20014182L (es)
NZ (1) NZ514442A (es)
PL (2) PL206121B1 (es)
PT (2) PT1161274E (es)
SI (2) SI1180378T1 (es)
TR (1) TR200102563T2 (es)
WO (1) WO2000051672A1 (es)

Families Citing this family (262)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070086954A1 (en) * 1998-11-23 2007-04-19 Miller Christopher C Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
GB0114272D0 (en) * 2001-06-12 2001-08-01 Optinose As Nasal delivery device
ES2235836T3 (es) * 1999-03-03 2005-07-16 Optinose As Dispositivo de entrega nasal.
GB0121568D0 (en) * 2001-09-06 2001-10-24 Optinose As Nasal delivery device
WO2001003645A2 (en) 1999-07-12 2001-01-18 Capnia, Incorporated Methods and apparatus for relieving headaches, rhinitis and other common ailments
JP2004500168A (ja) * 1999-11-08 2004-01-08 キャプニア インコーポレイテッド ガスと薬剤とを共投与して両者の相乗効果で頭痛やアンギナ及び他の症状を軽減するための方法及び装置
US20060172017A1 (en) 1999-11-08 2006-08-03 Capnia, Incorporated Methods and apparatus for the enhanced delivery of physiologic agents to tissue surfaces
US20070039615A1 (en) 1999-11-08 2007-02-22 Capnia, Incorporated Methods and apparatus for treating rhinitis
US7516742B2 (en) * 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US7122018B2 (en) * 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
US6432077B1 (en) * 2000-12-26 2002-08-13 Sensormedics Corporation Device and method for treatment of surface infections with nitric oxide
US7335181B2 (en) 2000-12-26 2008-02-26 Pulmonox Technologies Corporation Nitric oxide decontamination of the upper respiratory tract
US20110301569A1 (en) * 2001-01-20 2011-12-08 Gordon Wayne Dyer Methods and apparatus for the CVCS
ZA200306564B (en) * 2001-02-26 2004-10-15 Optinose As Nasal devices.
SE0101825D0 (sv) * 2001-05-22 2001-05-22 Astrazeneca Ab An Inhalation device
US7456184B2 (en) * 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
CA2462200A1 (en) * 2001-08-10 2003-02-20 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
US7732451B2 (en) * 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7655658B2 (en) * 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
GB2395909B (en) * 2001-09-06 2005-02-16 Optinose As Nasal delivery device
EP1450885B1 (en) 2001-09-28 2015-04-22 Kurve Technology, Inc. Nasal nebulizer
NZ570486A (en) * 2001-12-31 2010-01-29 Cns Inc Nasal devices including dilation and user comminication and methods if using same
US6760556B2 (en) 2002-07-16 2004-07-06 Cf Technologies Sealing member and toner container provided with such a sealing member
GB0207422D0 (en) * 2002-03-28 2002-05-08 Optinose As Nasal devices
GB0207817D0 (en) 2002-04-04 2002-05-15 Optinose As Nasal devices
GB0209494D0 (en) * 2002-04-25 2002-06-05 Optinose As Nasal devices
AU2003249623A1 (en) 2002-05-09 2003-12-12 Kurve Technology, Inc. Particle dispersion chamber for nasal nebulizer
GB0215270D0 (en) 2002-07-02 2002-08-14 Optinose As Nasal devices
GB0215904D0 (en) * 2002-07-09 2002-08-21 Team Holdings Uk Ltd Drug delivery system and method
DE10239321B3 (de) * 2002-08-27 2004-04-08 Pari GmbH Spezialisten für effektive Inhalation Aerosoltherapievorrichtung
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
US8317816B2 (en) 2002-09-30 2012-11-27 Acclarent, Inc. Balloon catheters and methods for treating paranasal sinuses
GB0300008D0 (en) 2003-01-02 2003-02-05 Optinose As Delivery devices
US7544192B2 (en) * 2003-03-14 2009-06-09 Sinexus, Inc. Sinus delivery of sustained release therapeutics
GB2400565B (en) * 2003-04-17 2005-03-02 Bespak Plc Nasal drug delivery
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7968548B2 (en) * 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
GB0311570D0 (en) * 2003-05-20 2003-06-25 Optinose As Delivery device and method
US7353826B2 (en) * 2003-08-08 2008-04-08 Cardinal Health 205, Inc. Sealing nasal cannula
GB0319119D0 (en) 2003-08-14 2003-09-17 Optinose As Delivery devices
GB0320171D0 (en) 2003-08-28 2003-10-01 Optinose As Delivery devices
US8474452B2 (en) 2004-02-24 2013-07-02 Microdose Therapeutx, Inc. Directional flow sensor inhaler
US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US8702626B1 (en) 2004-04-21 2014-04-22 Acclarent, Inc. Guidewires for performing image guided procedures
US9101384B2 (en) 2004-04-21 2015-08-11 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat
US9554691B2 (en) 2004-04-21 2017-01-31 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8747389B2 (en) 2004-04-21 2014-06-10 Acclarent, Inc. Systems for treating disorders of the ear, nose and throat
US20060063973A1 (en) 2004-04-21 2006-03-23 Acclarent, Inc. Methods and apparatus for treating disorders of the ear, nose and throat
US9351750B2 (en) 2004-04-21 2016-05-31 Acclarent, Inc. Devices and methods for treating maxillary sinus disease
US9089258B2 (en) 2004-04-21 2015-07-28 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9399121B2 (en) 2004-04-21 2016-07-26 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US7559925B2 (en) 2006-09-15 2009-07-14 Acclarent Inc. Methods and devices for facilitating visualization in a surgical environment
US7419497B2 (en) 2004-04-21 2008-09-02 Acclarent, Inc. Methods for treating ethmoid disease
US20190314620A1 (en) 2004-04-21 2019-10-17 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US10188413B1 (en) 2004-04-21 2019-01-29 Acclarent, Inc. Deflectable guide catheters and related methods
US20070208252A1 (en) 2004-04-21 2007-09-06 Acclarent, Inc. Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses
US7361168B2 (en) 2004-04-21 2008-04-22 Acclarent, Inc. Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders
US8932276B1 (en) 2004-04-21 2015-01-13 Acclarent, Inc. Shapeable guide catheters and related methods
US7803150B2 (en) 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8764729B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
US20070167682A1 (en) 2004-04-21 2007-07-19 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US20060004323A1 (en) 2004-04-21 2006-01-05 Exploramed Nc1, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US8864787B2 (en) 2004-04-21 2014-10-21 Acclarent, Inc. Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
US8894614B2 (en) 2004-04-21 2014-11-25 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US7462175B2 (en) 2004-04-21 2008-12-09 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
EP1755715A4 (en) 2004-05-11 2010-03-24 Sensormedics Corp INTERMITTENT DETERMINATION OF GASEOUS NITRIC OXIDE
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
AU2014253488A1 (en) * 2004-09-15 2014-11-13 Optinose As Nasal delivery devices
GB0420513D0 (en) * 2004-09-15 2004-10-20 Optinose As Powder delivery devices
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
EP1827385B1 (en) 2004-11-23 2013-03-27 Adamas Pharmaceuticals, Inc. Pharmaceutical composition comprising memantine in an extended dosage release form for use in the treatment of dementias
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
WO2006058236A2 (en) 2004-11-24 2006-06-01 Neuromolecular Pharmaceuticals, Inc. Composition comprising an nmda receptor antagonist and levodopa and use thereof for treating neurological disease
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427856D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
KR100675379B1 (ko) * 2005-01-25 2007-01-29 삼성전자주식회사 프린팅 시스템 및 프린팅 방법
GB0503738D0 (en) 2005-02-23 2005-03-30 Optinose As Powder delivery devices
US20090136505A1 (en) 2005-02-23 2009-05-28 Johanna Bentz Intranasal Administration of Active Agents to the Central Nervous System
CA2598666A1 (en) * 2005-02-23 2006-08-31 Alza Corporation Intranasal administration of active agents to the central nervous system
EP2298317A1 (en) 2005-04-04 2011-03-23 Sinexus, Inc. Device and methods for treating paranasal sinus conditions
JP5666087B2 (ja) 2005-04-06 2015-02-12 アダマス・ファーマシューティカルズ・インコーポレーテッド Cns関連疾患の治療のための方法及び組成物
US8951225B2 (en) 2005-06-10 2015-02-10 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US20060289006A1 (en) * 2005-06-27 2006-12-28 Kos Life Sciences, Inc. Breath actuated nasal drug delivery system
US8114113B2 (en) 2005-09-23 2012-02-14 Acclarent, Inc. Multi-conduit balloon catheter
US7846445B2 (en) * 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
EP1929073A4 (en) * 2005-09-27 2010-03-10 Amunix Inc PROTEIN MEDICAMENT AND ITS USE
US7855279B2 (en) * 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
US20090099031A1 (en) * 2005-09-27 2009-04-16 Stemmer Willem P Genetic package and uses thereof
WO2007037748A1 (en) * 2005-09-28 2007-04-05 Mederio Ag Inhaler device for moisture sensitive drugs and method of operating an inhaler device.
US20070068524A1 (en) * 2005-09-28 2007-03-29 Microdrug Ag Inhaler for moisture sensitive drugs
DE102006009637A1 (de) 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator mit Mundstück mit mikrobiologischer Schutzfunktion
DE102005054383B4 (de) 2005-11-15 2013-10-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Nadel zum Lochen von Pulverkapseln für die Inhalation
US20070116785A1 (en) * 2005-11-18 2007-05-24 Miller Christopher C Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
US7640934B2 (en) * 2005-12-02 2010-01-05 Carefusion 2200, Inc. Infant nasal interface prong device
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
AR058289A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
DE102006001113B3 (de) * 2006-01-09 2007-06-28 Pari GmbH Spezialisten für effektive Inhalation Aerosoltherapievorrichtung
WO2007083073A1 (en) * 2006-01-19 2007-07-26 Optinose As Nasal administration
GB0602980D0 (en) * 2006-02-14 2006-03-29 Optinose As Delivery device and method
WO2007093784A1 (en) * 2006-02-14 2007-08-23 Optinose As Delivery device and method
GB0604319D0 (en) * 2006-03-03 2006-04-12 Optinose As Nasal delivery
GB0604444D0 (en) * 2006-03-06 2006-04-12 Optinose As Nasal devices
US8486050B2 (en) * 2006-03-17 2013-07-16 Jackey Chiou Bubble-type nose cleaner
GB0605799D0 (en) 2006-03-23 2006-05-03 Optinose As Nasal delivery devices
DE102006016904A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102006016901A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
DE102006016903A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
GB2437488A (en) * 2006-04-25 2007-10-31 Optinose As Pharmaceutical oily formulation for nasal or buccal administration
GB2438834A (en) * 2006-06-08 2007-12-12 Optinose As Intranasal protein administration
US8535707B2 (en) * 2006-07-10 2013-09-17 Intersect Ent, Inc. Devices and methods for delivering active agents to the osteomeatal complex
GB2440316A (en) 2006-07-25 2008-01-30 Optinose As Nasal inhaler with scrubber
US7834017B2 (en) 2006-08-11 2010-11-16 Palatin Technologies, Inc. Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
JP2010502388A (ja) * 2006-09-06 2010-01-28 アボツト・レスピラトリー・エル・エル・シー 可変投与量のエアロゾル薬用キャニスター
US9820688B2 (en) 2006-09-15 2017-11-21 Acclarent, Inc. Sinus illumination lightwire device
US8079998B2 (en) * 2006-10-20 2011-12-20 Pulmonox Technologies Corporation Methods and devices for the delivery of therapeutic gases including nitric oxide
GB0623731D0 (en) 2006-11-28 2007-01-10 Optinose As Delivery device
GB2477225B (en) * 2006-11-28 2012-04-04 Optinose As Nasal delivery devices
GB0623728D0 (en) 2006-11-28 2007-01-10 Optinose As Delivery devices
GB2468794B (en) * 2006-11-28 2011-07-13 Optinose As Delivery devices
GB0623732D0 (en) 2006-11-28 2007-01-10 Optinose As Powder delivery devices
US20080178872A1 (en) * 2006-12-01 2008-07-31 Perry Genova Dose selective breath actuated inhaler
JP5502494B2 (ja) 2007-01-22 2014-05-28 ターガセプト・インコーポレイテッド メタニコチンアナログの鼻腔内、バッカル、または舌下投与
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
US8048023B2 (en) * 2007-03-06 2011-11-01 Rhinosystems Inc. Systems and methods for nasal irrigation
GB2448183A (en) * 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
GB2448193A (en) 2007-04-05 2008-10-08 Optinose As Nasal delivery device
EP1980285B1 (de) * 2007-04-11 2009-11-18 PARI GmbH Spezialisten für effektive Inhalation Aerosoltherapievorrichtung
US8714153B2 (en) * 2007-04-16 2014-05-06 Ric Investments, Llc Method for selecting a device adapted to treat disordered breathing
US8118757B2 (en) 2007-04-30 2012-02-21 Acclarent, Inc. Methods and devices for ostium measurement
US8485199B2 (en) 2007-05-08 2013-07-16 Acclarent, Inc. Methods and devices for protecting nasal turbinate during surgery
WO2008144106A1 (en) * 2007-05-16 2008-11-27 Aradigm Corporation Burst valve for aerosol device
US10293123B2 (en) 2007-05-23 2019-05-21 Shin Nippon Biomedical Laboratories, Ltd. Test substance administration system for animal experiment
DE102007033860A1 (de) 2007-07-20 2009-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Prüfvorrichtung
CA2695374A1 (en) * 2007-08-15 2009-02-19 Amunix, Inc. Compositions and methods for modifying properties of biologically active polypeptides
GB0719299D0 (en) 2007-10-03 2007-11-14 Optinose As Nasal delivery devices
DE102007052871A1 (de) 2007-11-02 2009-05-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Kapsel zur Aufnahme von pharmazeutischen Wirkstoffformulierungen
CN101945621B (zh) 2007-12-18 2014-06-18 因特尔赛克特耳鼻喉公司 自扩展装置及用于其的方法
US10206821B2 (en) 2007-12-20 2019-02-19 Acclarent, Inc. Eustachian tube dilation balloon with ventilation path
JP2011511674A (ja) 2008-02-07 2011-04-14 ユニヴァーシティ オブ ワシントン 周方向エアロゾルデバイス
US8182432B2 (en) 2008-03-10 2012-05-22 Acclarent, Inc. Corewire design and construction for medical devices
MX2011001099A (es) 2008-07-30 2011-03-15 Acclarent Inc Metodos y dispositivos localizadores de ostium paranasal.
AU2009276505B2 (en) 2008-08-01 2015-04-23 Intersect Ent, Inc. Methods and devices for crimping self-expanding devices
AU2009293312B2 (en) 2008-09-18 2015-07-09 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
DE202008015493U1 (de) 2008-11-21 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Faltschachtel
FR2938770B1 (fr) * 2008-11-27 2011-08-26 Diffusion Tech Francaise Sarl Dispositif d'administration de gaz et d'aerosol a visee nasale ou nasosinusienne
WO2010068683A1 (en) * 2008-12-09 2010-06-17 Dynova Laboratories, Inc. Dispensing head for nasal cleaning
CN102348715B (zh) 2009-02-03 2017-12-08 阿穆尼克斯运营公司 延伸重组多肽和包含该延伸重组多肽的组合物
US8716448B2 (en) 2009-02-03 2014-05-06 Amunix Operating Inc. Coagulation factor VII compositions and methods of making and using same
US20100241155A1 (en) 2009-03-20 2010-09-23 Acclarent, Inc. Guide system with suction
US7978742B1 (en) 2010-03-24 2011-07-12 Corning Incorporated Methods for operating diode lasers
US8435290B2 (en) 2009-03-31 2013-05-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
CN102639168A (zh) * 2009-04-27 2012-08-15 阿达瓦克医疗有限公司 冲洗和吸引装置及方法
WO2010126586A1 (en) * 2009-04-27 2010-11-04 Aardvark Medical, Llc Irrigation and aspiration devices and methods
WO2010132648A1 (en) 2009-05-15 2010-11-18 Intersect Ent, Inc. Expandable devices and methods therefor
EP2440241B1 (en) 2009-06-08 2017-08-09 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
PT2440228T (pt) 2009-06-08 2018-12-24 Amunix Operating Inc Polipéptidos de regulação da glicose e métodos de preparação e utilização dos mesmos
EP2440251A4 (en) 2009-06-09 2013-01-16 Defyrus Inc INTERFERON ADMINISTRATION FOR PROPHYLAXIS AGAINST PATHOGEN INFECTION OR TREATMENT OF PATHOGEN INFECTION
WO2011013003A2 (en) 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
FR2952042B1 (fr) * 2009-11-03 2012-01-20 Valois Sas Dispositif de distribution de produit fluide.
CA2782556C (en) 2009-12-02 2018-03-27 Adamas Pharmaceuticals, Inc. Amantadine compositions and methods of use
US20110139163A1 (en) * 2009-12-15 2011-06-16 Hillila David J Vibration apparatus for stimulating paranasal sinuses
FR2954707B1 (fr) * 2009-12-28 2016-01-08 Diffusion Tech Francaise Sarl Dispositif d'administration d'aerosol par voie buccale a visee rhinopharyngee, nasale ou nasosinusienne
FR2960423B1 (fr) * 2010-05-27 2013-03-08 Laurent Michel Marie Charroin Dispositif d'administration de liquide charge ou non de substances a visee naso-sinusienne
WO2012029064A1 (en) 2010-09-02 2012-03-08 Sipnose Ltd A nasal delivary device
GB201015371D0 (en) 2010-09-14 2010-10-27 Optinose As Nasal delivery
EP2431732A1 (en) * 2010-09-21 2012-03-21 Dow Global Technologies LLC Linking on-line analysis and tracer technology
US9155492B2 (en) 2010-09-24 2015-10-13 Acclarent, Inc. Sinus illumination lightwire device
ES2659761T3 (es) 2011-01-31 2018-03-19 Shin Nippon Biomedical Laboratories, Ltd. Dispositivos de administración intranasal
US20120204887A1 (en) * 2011-02-11 2012-08-16 Connor Robert A Adjustable Snore-Attenuating Pressure (ASAP)
BR122021002471B8 (pt) 2011-03-03 2022-10-25 Impel Neuropharma Inc Dispositivo de distribuição de droga nasal
US9949923B2 (en) * 2011-03-15 2018-04-24 Optinose As Nasal delivery
CN107376071B (zh) 2011-05-09 2021-07-09 英倍尔药业股份有限公司 用于将化合物递送到使用者的上部嗅觉区的喷嘴
US8944052B2 (en) * 2011-05-26 2015-02-03 Ivan Osorio Apparatus and methods for delivery of therapeutic agents to mucous or serous membrane
MX354213B (es) 2011-07-18 2018-02-15 Rhinosystems Inc Dispositivo de irrigación nasal y sistema con elemento de cartucho plegable de prueba.
GB2496684A (en) 2011-11-21 2013-05-22 Adi Wallach Breathing biofeedback device optionally comprising inhalable substance dispenser and breathing feedback methods
US20140364758A1 (en) * 2011-12-19 2014-12-11 Resmed Limited Respiratory treatment system including physiological sensors
KR20190094480A (ko) 2012-02-15 2019-08-13 바이오버라티브 테라퓨틱스 인크. 재조합 인자 viii 단백질
CN111548418A (zh) 2012-02-15 2020-08-18 比奥贝拉蒂治疗公司 因子viii组合物及其制备和使用方法
CA2865355C (en) 2012-02-24 2021-02-16 Optinose As Nasal delivery devices
EP2817052B1 (en) 2012-02-24 2017-09-13 Optinose AS Nasal delivery devices
IN2014DN07611A (es) 2012-02-24 2015-05-15 Optinose As
JP6322626B2 (ja) 2012-06-08 2018-05-09 アルカーメス,インコーポレイテッド ムチン−ドメインポリペプチドリンカーを含む融合ポリペプチド
US9456916B2 (en) 2013-03-12 2016-10-04 Medibotics Llc Device for selectively reducing absorption of unhealthy food
CN104470569B (zh) * 2012-06-28 2018-04-27 美国政府(由卫生和人类服务部的部长所代表) 用于疫苗和其它治疗试剂的鼻干粉递送系统
DE202012008892U1 (de) * 2012-09-14 2013-12-16 5med GmbH Nasenapplikator
US9415033B2 (en) 2012-10-03 2016-08-16 Proponent Biotech Gmbh Esters of short chains fatty acids for use in the treatment of immunogenic disorders
US9433724B2 (en) * 2012-10-30 2016-09-06 Preva, Llc. Irrigation assembly
US11179513B2 (en) 2012-10-30 2021-11-23 Preva, Llc Irrigation assembly
US10478547B2 (en) 2012-10-30 2019-11-19 Preva, Llc. Irrigation assembly
US9795756B2 (en) 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
US9032959B2 (en) 2012-12-04 2015-05-19 Ino Therapeutics Llc Cannula for minimizing dilution of dosing during nitric oxide delivery
US9737562B2 (en) 2012-12-11 2017-08-22 The Mclean Hospital Corporation Xenon and/or argon treatment as an adjunct to psychotherapy for psychiatric disorders
EP3597220A1 (en) 2013-02-26 2020-01-22 Baxalta GmbH Treatment of central nervous system disorders by intranasal administration of immunoglobulin g
EP3650067A1 (en) * 2013-03-11 2020-05-13 John R. Collins Inhalator device and method
US9011365B2 (en) 2013-03-12 2015-04-21 Medibotics Llc Adjustable gastrointestinal bifurcation (AGB) for reduced absorption of unhealthy food
US9067070B2 (en) 2013-03-12 2015-06-30 Medibotics Llc Dysgeusia-inducing neurostimulation for modifying consumption of a selected nutrient type
CN105188831B (zh) 2013-03-14 2021-01-01 因特尔赛克特耳鼻喉公司 用于治疗鼻窦病状的系统、装置以及方法
US9433437B2 (en) 2013-03-15 2016-09-06 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
US9629684B2 (en) 2013-03-15 2017-04-25 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
US10493226B2 (en) 2013-03-15 2019-12-03 Seedlings Life Science Ventures, Llc System and assembly for inflating and monitoring pressure within a retaining cuff
ES2920802T3 (es) 2013-03-26 2022-08-09 Optinose As Administración nasal
USD732659S1 (en) 2013-03-26 2015-06-23 Pediatric Innovations USA, LLC Car-shaped nasal device
US11554229B2 (en) 2013-03-26 2023-01-17 OptiNose Inc. Nasal administration
USD732658S1 (en) 2013-03-26 2015-06-23 Pediatric Innovations USA, LLC Nasal device with airplane wings
EP2991713B1 (en) 2013-04-28 2019-06-19 Impel Neuropharma Inc. Medical unit dose container
USD761951S1 (en) 2013-05-23 2016-07-19 Optinose As Nosepiece unit
WO2014204933A1 (en) 2013-06-17 2014-12-24 Adamas Pharmaceuticals, Inc. Amantadine compositions and methods of use
CN103405835B (zh) * 2013-07-31 2015-03-04 解秀丽 综合医疗雾化器
TW202003554A (zh) 2013-08-14 2020-01-16 美商百歐維拉提夫治療公司 因子viii-xten融合物及其用途
EP2868334B1 (de) * 2013-11-05 2017-01-11 Benedict Gerber Nasendusche
US9289547B2 (en) 2014-02-13 2016-03-22 Preva, Llc Nasal irrigation assembly and system
US11311706B2 (en) 2014-02-13 2022-04-26 Preva, Llc Nasal irrigation assembly and system
US10265462B2 (en) 2014-02-13 2019-04-23 Preva, Llc. Nasal irrigation assembly and system
MX2016017038A (es) 2014-06-25 2017-05-01 Optinose As Administracion nasal.
CN107106792B (zh) 2014-11-19 2020-08-18 奥普蒂诺斯公司 经鼻给药
US11077236B2 (en) * 2014-12-15 2021-08-03 Genicon, Inc. Powered lavage handle and associated use therefore
FR3031313A1 (fr) * 2015-01-05 2016-07-08 Air Liquide Medical Systems Appareil d'assistance respiratoire avec detection de tout arret de la turbine
US20160199599A1 (en) * 2015-01-13 2016-07-14 Bhl Patent Holdings Llc Nasal Delivery Device and Methods of Use
NZ706864A (en) 2015-04-09 2016-07-29 Aft Pharmaceuticals Ltd A nasal medication delivery device
JP6909203B2 (ja) 2015-08-03 2021-07-28 バイオベラティブ セラピューティクス インコーポレイテッド 第ix因子融合タンパク質及びそれらの製造方法及び使用方法
JP6753927B2 (ja) 2015-09-10 2020-09-09 インペル ニューロファーマ インコーポレイテッド 直列形経鼻送達デバイス
RU2728749C2 (ru) 2015-12-24 2020-07-30 Филип Моррис Продактс С.А. Гибкие устройства, генерирующие аэрозоль
US10206432B2 (en) 2015-12-24 2019-02-19 Altria Client Services Llc Flexible aerosol-generating devices
ES2899212T3 (es) 2016-02-04 2022-03-10 Propel Air Biopharma Llc Dispositivo de administración de medicamento
GB201619637D0 (en) 2016-11-21 2017-01-04 Pekna Marcela And Pekny Milos And Stokowska Anna C3a receptor agonists
DE102017004224A1 (de) * 2016-12-13 2018-11-08 Drägerwerk AG & Co. KGaA Nasenkanüle für High-Flow-Beatmung
WO2018200885A1 (en) 2017-04-26 2018-11-01 Neurocentria, Inc. Magnesium compositions and methods of use
CN107376063B (zh) * 2017-07-04 2020-08-21 浙江医尔仁医疗科技有限公司 中西药靶向雾化装置
IL254328B (en) 2017-09-04 2022-01-01 Jerasi Meir An improved device for enhancing nostril breathing
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
WO2019074799A1 (en) * 2017-10-09 2019-04-18 Pearl Therapeutics, Inc. DRUG DELIVERY SYSTEMS AND ASSOCIATED METHODS
EP3713628A4 (en) 2017-11-21 2021-08-18 Impel Neuropharma Inc. INTRA-NASAL DEVICE WITH DIVER TUBE
CA3081680A1 (en) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with inlet interface
JP2021509677A (ja) 2018-01-05 2021-04-01 インペル ニューロファーマ インコーポレイテッド 精密嗅覚装置によるオランザピンの鼻孔間送達
CA3088942C (en) 2018-01-05 2023-01-03 Impel Neuropharma, Inc. Intranasal delivery of dihydroergotamine by precision olfactory device
EA039533B1 (ru) * 2018-03-07 2022-02-08 Перл Терапьютикс, Инк. Устройство для доставки лекарств
KR102125502B1 (ko) 2018-03-27 2020-06-22 대전대학교 산학협력단 다중시료흡입모듈을 이용한 냄새평가장치
US10525240B1 (en) * 2018-06-28 2020-01-07 Sandler Scientific LLC Sino-nasal rinse delivery device with agitation, flow-control and integrated medication management system
US11517548B2 (en) 2018-07-19 2022-12-06 Impel Pharmaceuticals Inc. Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease
CN109674495B (zh) * 2018-08-01 2021-02-26 浙江三创生物科技有限公司 给药方法及其装置
WO2020070321A2 (en) * 2018-10-04 2020-04-09 Optinose As Exhalation delivery system for and method of treating sinus disease
EP3906017A4 (en) 2019-01-03 2022-12-28 Impel Pharmaceuticals Inc. NASAL DRUG DELIVERY DEVICE
CN109939326B (zh) * 2019-04-18 2023-10-31 首都医科大学附属北京安贞医院 基于呼气压力的嗅觉训练装置
US11878109B2 (en) 2019-05-17 2024-01-23 Impel Pharmaceuticals Inc. Single-use nasal delivery device
US11103422B2 (en) 2019-06-09 2021-08-31 Kblv Medical, Llc Device and system for remote regulation and monitoring of drug delivery and method of same
CA3163543A1 (en) * 2020-01-22 2021-07-29 Virginia Commonwealth University Dry powder inhalers and interfaces for improved aerosol delivery to children
US11207057B1 (en) 2020-08-07 2021-12-28 Cyrano Medical, Inc. Nasopharyngeal sample collection devices and methods
CN113318304B (zh) * 2021-05-25 2023-01-31 新乡医学院第一附属医院 一种鼻腔局部循环雾化器及一种鼻腔雾化治疗方法
CN113546290A (zh) * 2021-08-19 2021-10-26 南京澳博工业智能科技研究院有限公司 一种鼻腔给药装置
WO2023135237A1 (en) 2022-01-14 2023-07-20 Cybin Irl Limited Tryptamine compositions and methods
CN115282411A (zh) * 2022-01-14 2022-11-04 温州医科大学 利用鼻嗅区递送药物入脑的输送系统及其应用方法
CN115282412B (zh) * 2022-01-14 2023-08-25 温州医科大学 经鼻腔进入血循环的给药装置及其应用方法
CN115300726A (zh) * 2022-01-14 2022-11-08 温州医科大学 鼻腔专用输送系统及其应用方法
DE102022000297A1 (de) 2022-01-26 2023-07-27 Florian Matl Gerät zur verabreichung eines aerosols an den nasenraum, aktivierungsvorrichtung und aerosol-erzeugungsvorrichtung
WO2023156453A1 (en) 2022-02-15 2023-08-24 Cybin Irl Limited Phenethylamine derivatives, compositions, and methods of use
WO2023156450A1 (en) 2022-02-15 2023-08-24 Cybin Irl Limited Therapeutic phenethylamine compositions and methods of use
WO2023165486A1 (zh) * 2022-03-01 2023-09-07 园丁医疗科技(苏州)有限公司 一种口呼气传感的电动鼻腔冲洗器
WO2023186963A1 (en) 2022-03-31 2023-10-05 Cybin Irl Limited Combination of nitrous oxide and 5-ht2a receptor agonists

Family Cites Families (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US605436A (en) * 1898-06-07 Inhaler
US39678A (en) * 1863-08-25 Improvement in powder-injectors
US419942A (en) * 1890-01-21 Insufflator
US429321A (en) * 1890-06-03 Inhaler
US642748A (en) * 1899-02-23 1900-02-06 Arthur Manners Inhaler.
US658436A (en) * 1900-05-28 1900-09-25 Hans Hennerich Groth Insufflator.
US707445A (en) * 1902-04-10 1902-08-19 John Howard Mcculloch Inhaler.
US723738A (en) * 1902-06-05 1903-03-24 August K Schulte Inhaler.
US746749A (en) 1903-03-18 1903-12-15 George E Seidel Nasal medicator.
US781428A (en) * 1904-07-28 1905-01-31 Sheridan J Hutchins Inhaler, injector, and medicator.
US794641A (en) * 1905-03-06 1905-07-11 Alfred H Ramey Inhaler.
US867827A (en) * 1906-05-14 1907-10-08 John Howard Mcculloch Inhaler.
US902832A (en) * 1907-09-20 1908-11-03 Edward F Philbrook Inhaler.
US1375325A (en) * 1920-06-29 1921-04-19 Schaefer William Henry Inhaler
US1540274A (en) * 1924-03-28 1925-06-02 William J Moore Nasal inhaler
US1873160A (en) * 1929-02-08 1932-08-23 Harold V Sturtevant Breathing apparatus
US2021332A (en) * 1931-11-28 1935-11-19 Silten Ernst Inhalation apparatus
GB408856A (en) 1933-08-14 1934-04-19 Wietske Van Seters Bosch Improvements in and relating to inhalers
US2086588A (en) * 1935-11-18 1937-07-13 Joseph J Tobin Vaporizing applicator
US2223611A (en) * 1939-05-22 1940-12-03 Richard E Gross Syringe
US2693805A (en) * 1947-03-08 1954-11-09 George V Taplin Apparatus for administering therapeutic agents
US2546214A (en) * 1947-03-17 1951-03-27 Harold E Curry Applicator
BE483136A (es) 1947-09-04 1942-06-30
US2945495A (en) * 1958-03-05 1960-07-19 Waldo R Griffin Nasal irrigator
US3605738A (en) * 1969-06-20 1971-09-20 Paul J Ciranna Medicinal spray device
US3847145A (en) * 1973-04-13 1974-11-12 M Grossan Nasal irrigation system
US3888252A (en) 1974-01-23 1975-06-10 Anthony J Side Powder inhaler
US3949939A (en) * 1975-03-26 1976-04-13 Smithkline Corporation Metered spray device
US4216768A (en) * 1978-03-23 1980-08-12 Whitfield Jack Device for inhaling powdered substance
US4265236A (en) * 1980-03-31 1981-05-05 Pacella Angelo M Portable inhalator device
DE3018691C2 (de) 1980-05-16 1982-10-28 Gerhard 7166 Sulzbach-Laufen Hansen Vorrichtung zum Selbsteinblasen eines pulverförmigen oder flüssigen Stoffes in eine Körperöffnung
US4325366A (en) * 1980-07-07 1982-04-20 Tabor Carl J Valve and method for use with a tracheotomy tube
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
FI69962C (fi) * 1983-12-28 1986-09-12 Huhtamaeki Oy Inhalationsanordning
US4660555A (en) * 1984-09-21 1987-04-28 Payton Hugh W Oxygen delivery and administration system
US4674494A (en) * 1985-05-10 1987-06-23 The Kendall Company Humidifying device
US4782832A (en) * 1987-07-30 1988-11-08 Puritan-Bennett Corporation Nasal puff with adjustable sealing means
US5046493A (en) * 1988-02-16 1991-09-10 James Kropkowski Nasal dispenser
GB8810898D0 (en) 1988-05-09 1988-06-15 Bespak Plc Improvements in dispensing apparatus
US4919128A (en) 1988-08-26 1990-04-24 University Technologies International Inc. Nasal adaptor device and seal
FR2638361B1 (fr) 1988-10-28 1991-01-11 Diffusion Tech Francaise Sarl Embout narinaire adaptable sur tous appareils a usage medical du type nebuliseurs et autres
WO1990013327A1 (en) 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
CA2003895C (en) * 1989-11-16 1999-03-30 Jean-Pierre Robitaille Filtre intra-nasal
US5167242A (en) 1990-06-08 1992-12-01 Kabi Pharmacia Aktiebolaq Nicotine-impermeable container and method of fabricating the same
AU9089591A (en) 1990-12-17 1992-07-22 Minnesota Mining And Manufacturing Company Inhaler
US5477852A (en) * 1991-10-29 1995-12-26 Airways Ltd., Inc. Nasal positive airway pressure apparatus and method
US5373841A (en) 1992-02-04 1994-12-20 Kyllonen; David M. Self-operated nasal humidifier
US5222491A (en) * 1992-05-29 1993-06-29 Thomas Samuel D Temporary patient ventilator
US5284133A (en) * 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
GB2270293A (en) 1992-09-05 1994-03-09 Medix Ltd Drug dispensing system
FR2696080B1 (fr) 1992-09-30 1994-12-23 Jesus Covarrubias Filtre à cigarette pour l'administration de taurine par inhalation.
US5507277A (en) * 1993-01-29 1996-04-16 Aradigm Corporation Lockout device for controlled release of drug from patient-activateddispenser
DE69413387T2 (de) 1993-02-12 1999-02-04 Minnesota Mining & Mfg Aerosol-abgabevorrichtung
US5560354A (en) 1993-06-18 1996-10-01 Rescare Limited Facial masks for assisted respiration or CPAP
US5437267A (en) * 1993-08-03 1995-08-01 Weinstein; Allan Device for delivering aerosol to the nasal membranes and method of use
US5375593A (en) * 1994-02-10 1994-12-27 Press; John R. Oxygenating pacifier
GB9415722D0 (en) 1994-08-03 1994-09-21 Fxk Patents Ltd Breathing equipment
PT805696E (pt) 1995-01-23 2000-08-31 Direct Haler A S Inalador
US5653961A (en) * 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
US5645051A (en) * 1995-04-21 1997-07-08 Dura Pharmaceuticals, Inc. Unit dose dry powder inhaler
US5850833A (en) 1995-05-22 1998-12-22 Kotliar; Igor K. Apparatus for hypoxic training and therapy
JP3434396B2 (ja) 1995-06-30 2003-08-04 株式会社日立ユニシアオートモティブ 鼻腔用投薬器
SE506208C2 (sv) * 1995-07-05 1997-11-24 Aerocrine Systems Kb Anordning för uppsamling av gas från de övre luftvägarna och leverans av denna gas till inandningsluften i en respirator
US5692496A (en) * 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
SE9502800D0 (sv) 1995-08-10 1995-08-10 Astra Ab Disposable inhaler
US5848587A (en) * 1995-09-21 1998-12-15 Medi-Nuclear Corporation, Inc. Aerosol medication delivery system
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
US5694920A (en) * 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
AU2343097A (en) * 1996-03-21 1997-10-10 Mpath Interactive, Inc. Network match maker for selecting clients based on attributes of servers and communication links
FR2747311B1 (fr) * 1996-04-10 1998-08-14 Pf Medicament Inhalateur a poudre et a air comprime
US6074673A (en) * 1996-04-22 2000-06-13 Guillen; Manuel Slow-release, self-absorbing, drug delivery system
US5957125A (en) * 1996-11-05 1999-09-28 Medical Safety Products, Inc. Apparatus for indicating proper orientation for oral and nasal inhalers
US5752510A (en) * 1996-11-14 1998-05-19 Goldstein; Joseph Nasal and oral air passageway delivery management apparatus
US5829435A (en) * 1997-02-24 1998-11-03 Aradigm Corporation Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles
US6013623A (en) * 1997-02-27 2000-01-11 The Trustees Of Columbia University In The City Of New York Use of heme-peptides to prevent or retard disease associated with oxidative stress
US5855907A (en) * 1997-03-24 1999-01-05 Peyman; Gholam A. Method of treatment of migraine
US5865172A (en) * 1997-04-08 1999-02-02 The Board Of Regents Of The University Of Texas System Method and apparatus for induction of inhaled pharmacological agent by a pediatric patient
US5937852A (en) * 1997-04-08 1999-08-17 The Board Of Regents Of The University Of Texas System Apparatus for induction of inhaled pharmacological agent by a pediatric patient
US6125846A (en) * 1997-05-16 2000-10-03 Datex-Ohmeda, Inc. Purge system for nitric oxide administration apparatus
CZ296017B6 (cs) * 1997-05-27 2005-12-14 Direct-Haler A/S Zařízení pro aplikaci práškové či částicové substance
US5904140A (en) 1997-06-24 1999-05-18 Mcgoogan; Elizabeth M. Medical pacifier
US6182660B1 (en) * 1998-02-22 2001-02-06 William J. Hopper Non-invasive sinus pain relieving assembly
US6125844A (en) * 1998-04-30 2000-10-03 Westwood Biomedical Portable oxygen based drug delivery system
US6145503A (en) * 1998-07-13 2000-11-14 Smith; Ronnie Olfactory activator
ES2235836T3 (es) * 1999-03-03 2005-07-16 Optinose As Dispositivo de entrega nasal.
GB0114272D0 (en) * 2001-06-12 2001-08-01 Optinose As Nasal delivery device
GB0121568D0 (en) * 2001-09-06 2001-10-24 Optinose As Nasal delivery device
EP1110572A1 (de) * 1999-12-24 2001-06-27 Gert F. Kölbel Inhalationsgerät
GB0015309D0 (en) * 2000-06-21 2000-08-16 Djupesland Per G Apparatus
ZA200306564B (en) * 2001-02-26 2004-10-15 Optinose As Nasal devices.
GB0207422D0 (en) * 2002-03-28 2002-05-08 Optinose As Nasal devices
GB0209494D0 (en) * 2002-04-25 2002-06-05 Optinose As Nasal devices
GB0215270D0 (en) 2002-07-02 2002-08-14 Optinose As Nasal devices
GB0215904D0 (en) * 2002-07-09 2002-08-21 Team Holdings Uk Ltd Drug delivery system and method
GB0311570D0 (en) 2003-05-20 2003-06-25 Optinose As Delivery device and method
GB0319119D0 (en) * 2003-08-14 2003-09-17 Optinose As Delivery devices
GB0320171D0 (en) * 2003-08-28 2003-10-01 Optinose As Delivery devices
GB0420513D0 (en) * 2004-09-15 2004-10-20 Optinose As Powder delivery devices
GB0503738D0 (en) * 2005-02-23 2005-03-30 Optinose As Powder delivery devices
WO2007093784A1 (en) 2006-02-14 2007-08-23 Optinose As Delivery device and method
GB0602980D0 (en) 2006-02-14 2006-03-29 Optinose As Delivery device and method
GB0604319D0 (en) 2006-03-03 2006-04-12 Optinose As Nasal delivery
GB0604444D0 (en) 2006-03-06 2006-04-12 Optinose As Nasal devices
GB0605799D0 (en) 2006-03-23 2006-05-03 Optinose As Nasal delivery devices
GB2437488A (en) 2006-04-25 2007-10-31 Optinose As Pharmaceutical oily formulation for nasal or buccal administration
GB2440316A (en) 2006-07-25 2008-01-30 Optinose As Nasal inhaler with scrubber

Also Published As

Publication number Publication date
JP2002537908A (ja) 2002-11-12
HK1039459A1 (en) 2002-04-26
US20060225732A1 (en) 2006-10-12
EP2340865B1 (en) 2016-07-20
US20160095993A1 (en) 2016-04-07
SI1180378T1 (sl) 2011-04-29
CN1342093A (zh) 2002-03-27
ES2439274T3 (es) 2014-01-22
MXPA01008849A (es) 2003-07-21
CA2364009C (en) 2007-02-27
US20160250408A1 (en) 2016-09-01
US20060219241A1 (en) 2006-10-05
US8327844B2 (en) 2012-12-11
US6715485B1 (en) 2004-04-06
JP2010172761A (ja) 2010-08-12
IL144988A (en) 2011-08-31
US9072857B2 (en) 2015-07-07
DE60045216D1 (de) 2010-12-23
GB2349092A (en) 2000-10-25
US20060231094A1 (en) 2006-10-19
PT1180378E (pt) 2011-02-14
EP1180378A2 (en) 2002-02-20
CY1111201T1 (el) 2015-06-11
GB0005254D0 (en) 2000-04-26
EP1161274B1 (en) 2004-12-29
GB2349092B (en) 2001-07-25
ATE514445T1 (de) 2011-07-15
AU2822700A (en) 2000-09-21
HK1039459B (zh) 2005-05-13
DE60017099D1 (de) 2005-02-03
US8555878B2 (en) 2013-10-15
EP1161274A1 (en) 2001-12-12
EP2332603A3 (en) 2011-10-19
EP1555038B1 (en) 2011-06-29
EP1180378B1 (en) 2010-11-10
EP2332603A2 (en) 2011-06-15
CN1217712C (zh) 2005-09-07
ES2235836T3 (es) 2005-07-16
JP4543553B2 (ja) 2010-09-15
BR0008650A (pt) 2001-12-26
BR0008650B1 (pt) 2010-12-28
DK1180378T3 (da) 2011-02-21
US20060219240A1 (en) 2006-10-05
WO2000051672A1 (en) 2000-09-08
CN1736502A (zh) 2006-02-22
DE60017099T2 (de) 2006-01-12
JP5253452B2 (ja) 2013-07-31
PL206121B1 (pl) 2010-07-30
US8555877B2 (en) 2013-10-15
KR20010103036A (ko) 2001-11-17
PL350220A1 (en) 2002-11-18
EP2332603B1 (en) 2013-08-14
EP1555038A3 (en) 2006-05-10
EP3124067A3 (en) 2017-05-24
NZ514442A (en) 2003-08-29
NO20014182L (no) 2001-11-01
EP3124067A2 (en) 2017-02-01
EP2340865A1 (en) 2011-07-06
KR100692422B1 (ko) 2007-03-09
ATE285810T1 (de) 2005-01-15
EP1180378A3 (en) 2002-02-27
DK1161274T3 (da) 2005-05-09
AU766410B2 (en) 2003-10-16
TR200102563T2 (tr) 2002-04-22
ES2600357T3 (es) 2017-02-08
PT1161274E (pt) 2005-05-31
US20040182388A1 (en) 2004-09-23
NO20014182D0 (no) 2001-08-28
HK1044492A1 (zh) 2002-10-25
PL203959B1 (pl) 2009-11-30
ID30286A (id) 2001-11-15
ATE487506T1 (de) 2010-11-15
DK1555038T3 (da) 2011-10-17
EP1555038A2 (en) 2005-07-20
CA2364009A1 (en) 2000-09-08
SI1161274T1 (en) 2005-08-31
US9119932B2 (en) 2015-09-01
EP1180378B8 (en) 2011-03-09

Similar Documents

Publication Publication Date Title
GB2349092B (en) Nasal delivery device
GB2453389B (en) Nasal delivery system with replaceable nosepiece unit
EP1407795A3 (en) Nasal delivery devices
GB2374807B (en) Nasal devices
ATE331548T1 (de) Medikamentinhaliervorrichtung sowie verfahren
WO2005035021A3 (en) A nasal gas delivery system and method for use thereof