GB2453389B - Nasal delivery system with replaceable nosepiece unit - Google Patents

Nasal delivery system with replaceable nosepiece unit

Info

Publication number
GB2453389B
GB2453389B GB0723370A GB0723370A GB2453389B GB 2453389 B GB2453389 B GB 2453389B GB 0723370 A GB0723370 A GB 0723370A GB 0723370 A GB0723370 A GB 0723370A GB 2453389 B GB2453389 B GB 2453389B
Authority
GB
United Kingdom
Prior art keywords
substance
container
mouthpiece
subject
nosepiece
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB0723370A
Other versions
GB2453389A (en
GB0723370D0 (en
Inventor
Per Gisle Djupesland
Colin David Sheldrake
David Ellis
Simon Smith
Rachel Striebig
Andy Pidgeon
Tom St Quintin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Optinose AS
Original Assignee
Optinose AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optinose AS filed Critical Optinose AS
Priority to GB1103477.4A priority Critical patent/GB2477225B/en
Priority to GB1008408A priority patent/GB2470486B/en
Priority to GB1103476A priority patent/GB2477224A/en
Priority to GB1103474A priority patent/GB2477223A/en
Publication of GB0723370D0 publication Critical patent/GB0723370D0/en
Publication of GB2453389A publication Critical patent/GB2453389A/en
Application granted granted Critical
Publication of GB2453389B publication Critical patent/GB2453389B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0018Details of inhalators; Constructional features thereof with exhalation check valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0025Mouthpieces therefor with caps
    • A61M15/0026Hinged caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0041Details of the piercing or cutting means with movable piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043Non-destructive separation of the package, e.g. peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081Locking means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0098Activated by exhalation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/1045Devices for humidifying or heating the inspired gas by using recovered moisture or heat from the expired gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0222Materials for reducing friction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0618Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0625Mouth

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Formation And Processing Of Food Products (AREA)
  • External Artificial Organs (AREA)
  • Steroid Compounds (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

A nasal delivery device for delivering particulate substance to the nasal airway of a subject, the delivery device comprising: a mouthpiece unit (109) which includes a mouthpiece (147) through which the subject in use exhales; a nosepiece unit (105) which includes a nosepiece (141) for fitting to a nostril of the subject; and a substance-supply unit (111) which is configured to receive a container (C) containing particulate substance and operable to provide a metered amount of substance in fluid communication with the mouthpiece and nosepiece units (109, 105), such that an exhalation air flow delivered through the substance-supply unit (111) entrains the substance; wherein the container (C) comprises first and second parts (115, 117) which together define an enclosed chamber (119) and are movable between a first, closed configuration in which the container (C) is closed and a second, open configuration in which the container (C) is open, and the substance-supply unit (111) is operable to move the first and second parts (115, 117) of the container (C) to the open configuration.
GB0723370A 2006-11-28 2007-11-28 Nasal delivery system with replaceable nosepiece unit Active GB2453389B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB1103477.4A GB2477225B (en) 2006-11-28 2007-11-28 Nasal delivery devices
GB1008408A GB2470486B (en) 2006-11-28 2007-11-28 Nasal delivery devices
GB1103476A GB2477224A (en) 2006-11-28 2007-11-28 Nasal delivery system with a replaceable nosepiece unit
GB1103474A GB2477223A (en) 2006-11-28 2007-11-28 Nasal delivery system with a replaceable nosepiece unit

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0623732.5A GB0623732D0 (en) 2006-11-28 2006-11-28 Powder delivery devices

Publications (3)

Publication Number Publication Date
GB0723370D0 GB0723370D0 (en) 2008-01-09
GB2453389A GB2453389A (en) 2009-04-08
GB2453389B true GB2453389B (en) 2011-07-06

Family

ID=37671443

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB0623732.5A Ceased GB0623732D0 (en) 2006-11-28 2006-11-28 Powder delivery devices
GB0723370A Active GB2453389B (en) 2006-11-28 2007-11-28 Nasal delivery system with replaceable nosepiece unit

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB0623732.5A Ceased GB0623732D0 (en) 2006-11-28 2006-11-28 Powder delivery devices

Country Status (6)

Country Link
US (4) US9010325B2 (en)
EP (3) EP2139548B1 (en)
AT (1) ATE550062T1 (en)
ES (3) ES2595604T3 (en)
GB (2) GB0623732D0 (en)
WO (1) WO2008065403A2 (en)

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GB0311570D0 (en) * 2003-05-20 2003-06-25 Optinose As Delivery device and method
GB0319119D0 (en) 2003-08-14 2003-09-17 Optinose As Delivery devices
GB0320171D0 (en) * 2003-08-28 2003-10-01 Optinose As Delivery devices
GB0420513D0 (en) 2004-09-15 2004-10-20 Optinose As Powder delivery devices
GB0503738D0 (en) * 2005-02-23 2005-03-30 Optinose As Powder delivery devices
AU2006335994A1 (en) 2006-01-19 2007-07-26 Optinose As Nasal administration
GB0602980D0 (en) 2006-02-14 2006-03-29 Optinose As Delivery device and method
GB0604444D0 (en) 2006-03-06 2006-04-12 Optinose As Nasal devices
GB0605799D0 (en) 2006-03-23 2006-05-03 Optinose As Nasal delivery devices
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GB0623731D0 (en) 2006-11-28 2007-01-10 Optinose As Delivery device
GB0623732D0 (en) 2006-11-28 2007-01-10 Optinose As Powder delivery devices
GB0623728D0 (en) 2006-11-28 2007-01-10 Optinose As Delivery devices
GB2448193A (en) 2007-04-05 2008-10-08 Optinose As Nasal delivery device
GB2448183A (en) 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
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EP2460554A3 (en) 2013-01-23
ES2648144T3 (en) 2017-12-28
ES2595604T3 (en) 2017-01-02
EP2460555A2 (en) 2012-06-06
GB2453389A (en) 2009-04-08
WO2008065403A3 (en) 2008-11-20
US9010325B2 (en) 2015-04-21
EP2139548B1 (en) 2012-03-21
EP2139548A2 (en) 2010-01-06
WO2008065403A2 (en) 2008-06-05
EP2460555A3 (en) 2012-12-26
EP2460554A2 (en) 2012-06-06
GB0623732D0 (en) 2007-01-10
EP2460554B1 (en) 2016-06-29
ATE550062T1 (en) 2012-04-15
US10525218B2 (en) 2020-01-07
EP2460555B1 (en) 2017-09-20
US20100300439A1 (en) 2010-12-02
US20200338286A1 (en) 2020-10-29
ES2387300T3 (en) 2012-09-20
US20220273894A1 (en) 2022-09-01
US20160051778A1 (en) 2016-02-25
GB0723370D0 (en) 2008-01-09

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