IL143484A0 - New biphenyl and biphenyl-analogous compounds as integrin antagonists - Google Patents

New biphenyl and biphenyl-analogous compounds as integrin antagonists

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Publication number
IL143484A0
IL143484A0 IL14348499A IL14348499A IL143484A0 IL 143484 A0 IL143484 A0 IL 143484A0 IL 14348499 A IL14348499 A IL 14348499A IL 14348499 A IL14348499 A IL 14348499A IL 143484 A0 IL143484 A0 IL 143484A0
Authority
IL
Israel
Prior art keywords
biphenyl
integrin antagonists
analogous compounds
new
pharmaceutical compositions
Prior art date
Application number
IL14348499A
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English (en)
Original Assignee
Bayer Ag
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Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL143484A0 publication Critical patent/IL143484A0/xx

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
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HUP0105432A3 (en) 2002-12-28
CA2355161A1 (en) 2000-06-22
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