IL138745A0 - Pde iv inhibiting pyridine derivatives - Google Patents

Pde iv inhibiting pyridine derivatives

Info

Publication number
IL138745A0
IL138745A0 IL13874599A IL13874599A IL138745A0 IL 138745 A0 IL138745 A0 IL 138745A0 IL 13874599 A IL13874599 A IL 13874599A IL 13874599 A IL13874599 A IL 13874599A IL 138745 A0 IL138745 A0 IL 138745A0
Authority
IL
Israel
Prior art keywords
pde
pyridine derivatives
inhibiting
inhibiting pyridine
derivatives
Prior art date
Application number
IL13874599A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL138745A0 publication Critical patent/IL138745A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL13874599A 1998-04-01 1999-03-24 Pde iv inhibiting pyridine derivatives IL138745A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201020 1998-04-01
PCT/EP1999/002045 WO1999050262A1 (en) 1998-04-01 1999-03-24 Pde iv inhibiting pyridine derivatives

Publications (1)

Publication Number Publication Date
IL138745A0 true IL138745A0 (en) 2001-10-31

Family

ID=8233543

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13874599A IL138745A0 (en) 1998-04-01 1999-03-24 Pde iv inhibiting pyridine derivatives
IL138745A IL138745A (en) 1998-04-01 2000-09-28 Derived from pyridines that inhibit PDE IV, the compositions containing them, their uses and processes for their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL138745A IL138745A (en) 1998-04-01 2000-09-28 Derived from pyridines that inhibit PDE IV, the compositions containing them, their uses and processes for their preparation

Country Status (34)

Country Link
US (1) US6656959B1 (ja)
EP (1) EP1068194B1 (ja)
JP (1) JP4778612B2 (ja)
KR (1) KR100596664B1 (ja)
CN (1) CN1172930C (ja)
AR (1) AR014972A1 (ja)
AT (1) ATE253569T1 (ja)
AU (1) AU760771B2 (ja)
BG (1) BG64705B1 (ja)
BR (1) BR9909326A (ja)
CA (1) CA2326045C (ja)
CZ (1) CZ298747B6 (ja)
DE (1) DE69912590T2 (ja)
DK (1) DK1068194T3 (ja)
EA (1) EA004207B1 (ja)
EE (1) EE04718B1 (ja)
ES (1) ES2211061T3 (ja)
HK (1) HK1033579A1 (ja)
HR (1) HRP20000619B1 (ja)
HU (1) HU229412B1 (ja)
ID (1) ID27207A (ja)
IL (2) IL138745A0 (ja)
MY (1) MY124696A (ja)
NO (1) NO319531B1 (ja)
NZ (1) NZ507022A (ja)
PL (1) PL196026B1 (ja)
PT (1) PT1068194E (ja)
SI (1) SI1068194T1 (ja)
SK (1) SK284468B6 (ja)
TR (1) TR200002801T2 (ja)
TW (1) TWI242558B (ja)
UA (1) UA66842C2 (ja)
WO (1) WO1999050262A1 (ja)
ZA (1) ZA200006190B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY123585A (en) 2000-03-23 2006-05-31 Merck Canada Inc Tri-aryl-substituted-ethane pde4 inhibitors.
US6639077B2 (en) 2000-03-23 2003-10-28 Merck Frosst Canada & Co. Tri-aryl-substituted-ethane PDE4 inhibitors
DE10130397A1 (de) * 2001-06-23 2003-01-09 Bayer Cropscience Gmbh Herbizide substituierte Pyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbzide und Pflanzenwachstumsregulatoren
DE10318610A1 (de) * 2003-04-24 2004-11-11 Elbion Ag 7-Azaindole und deren Verwendung als Therapeutika
MXPA06012505A (es) 2004-04-30 2006-12-15 Warner Lambert Co Compuestos de morfolina sustituida para el tratamiento de trastornos del sistema nervioso central.
US7863446B2 (en) 2006-01-19 2011-01-04 Orchid Research Laboratories Limited Heterocycles
JP2009525269A (ja) 2006-01-30 2009-07-09 ユーロ−セルティーク エス.エイ. カルシウムチャネルブロッカーとしての環状尿素化合物
PL2076508T3 (pl) 2006-10-18 2011-05-31 Pfizer Prod Inc Związki biaryloeteru mocznika
RU2572616C2 (ru) 2008-02-01 2016-01-20 Оркид Рисерч Лабораториз Лимитед Новые гетероциклы
JOP20190060A1 (ar) 2016-09-26 2019-03-26 Chugai Pharmaceutical Co Ltd مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876657A (en) * 1971-06-03 1975-04-08 Ashland Oil Inc Preparation of 1-substituted-2-imidazolidinones
US4600430A (en) 1985-02-22 1986-07-15 Eli Lilly And Company Pyridinylimidazolidinone compounds
EP0711282B1 (en) * 1993-07-28 2002-06-05 Aventis Pharma Limited Compounds as pde iv and tnf inhibitors
GB9401460D0 (en) * 1994-01-26 1994-03-23 Rhone Poulenc Rorer Ltd Compositions of matter
WO1996004186A1 (en) * 1994-08-03 1996-02-15 Gics & Vermee, L.P. Ovenable food package
TW332201B (en) * 1995-04-06 1998-05-21 Janssen Pharmaceutica Nv 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives
TW375612B (en) * 1995-04-06 1999-12-01 Janssen Pharmaceutica Nv 1,3-dihydro-2H-imidazol-2-one derivatives for the treatment of disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase type IV, preparation thereof and pharmaceutical composition containing the same
TW424087B (en) * 1995-04-06 2001-03-01 Janssen Pharmaceutica Nv 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives
WO1997003967A1 (en) * 1995-07-22 1997-02-06 Rhone-Poulenc Rorer Limited Substituted aromatic compounds and their pharmaceutical use
BR9612378A (pt) * 1995-12-29 1999-07-13 Smithkline Beecham Corp Antagonistas receptores de vitronectina
SK285878B6 (sk) * 1996-10-02 2007-10-04 Janssen Pharmaceutica N. V. Derivát 2-kyaniminoimidazolu, prostriedok obsahujúci tento derivát, spôsob prípravy tohto prostriedku, uvedený derivát na použitie ako liečivo, použitie tohto derivátu na prípravu liečiva a spôsob prípravy tohto derivátu

Also Published As

Publication number Publication date
CZ20003338A3 (cs) 2001-02-14
KR100596664B1 (ko) 2006-07-06
NO319531B1 (no) 2005-08-29
HUP0101239A3 (en) 2002-09-30
HRP20000619B1 (en) 2004-06-30
SI1068194T1 (en) 2004-04-30
CN1172930C (zh) 2004-10-27
SK284468B6 (sk) 2005-04-01
EP1068194B1 (en) 2003-11-05
NO20004906D0 (no) 2000-09-29
AU3147499A (en) 1999-10-18
ES2211061T3 (es) 2004-07-01
ZA200006190B (en) 2001-10-31
MY124696A (en) 2006-06-30
PT1068194E (pt) 2004-03-31
TR200002801T2 (tr) 2000-12-21
EE04718B1 (et) 2006-10-16
BR9909326A (pt) 2000-12-12
UA66842C2 (uk) 2004-06-15
ID27207A (id) 2001-03-08
KR20010040681A (ko) 2001-05-15
SK13872000A3 (sk) 2001-11-06
EP1068194A1 (en) 2001-01-17
DE69912590D1 (de) 2003-12-11
HRP20000619A2 (en) 2001-10-31
CA2326045C (en) 2008-12-09
NZ507022A (en) 2002-06-28
AU760771B2 (en) 2003-05-22
CA2326045A1 (en) 1999-10-07
DE69912590T2 (de) 2004-09-16
PL343194A1 (en) 2001-07-30
TWI242558B (en) 2005-11-01
HK1033579A1 (en) 2001-09-07
BG64705B1 (bg) 2005-12-30
IL138745A (en) 2007-06-17
HUP0101239A2 (hu) 2002-05-29
WO1999050262A1 (en) 1999-10-07
EA004207B1 (ru) 2004-02-26
CN1295571A (zh) 2001-05-16
BG104718A (en) 2001-04-30
EA200001009A1 (ru) 2001-02-26
EE200000569A (et) 2002-04-15
PL196026B1 (pl) 2007-11-30
ATE253569T1 (de) 2003-11-15
CZ298747B6 (cs) 2008-01-16
HU229412B1 (en) 2013-12-30
JP2002509927A (ja) 2002-04-02
AR014972A1 (es) 2001-04-11
NO20004906L (no) 2000-11-28
US6656959B1 (en) 2003-12-02
DK1068194T3 (da) 2004-03-15
JP4778612B2 (ja) 2011-09-21

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