IL137955A - High cross-linked amylose with functional groups as a matrix for delayed release of pharmacological agents - Google Patents
High cross-linked amylose with functional groups as a matrix for delayed release of pharmacological agentsInfo
- Publication number
- IL137955A IL137955A IL13795599A IL13795599A IL137955A IL 137955 A IL137955 A IL 137955A IL 13795599 A IL13795599 A IL 13795599A IL 13795599 A IL13795599 A IL 13795599A IL 137955 A IL137955 A IL 137955A
- Authority
- IL
- Israel
- Prior art keywords
- cross
- high amylose
- amylose starch
- linking agent
- linked
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/028,385 US6284273B1 (en) | 1998-02-24 | 1998-02-24 | Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds |
PCT/CA1999/000169 WO1999043305A1 (en) | 1998-02-24 | 1999-02-24 | Cross-linked high amylose starch having functional groups as a matrix for the slow release of pharmaceutical agents |
Publications (2)
Publication Number | Publication Date |
---|---|
IL137955A0 IL137955A0 (en) | 2001-10-31 |
IL137955A true IL137955A (en) | 2005-12-18 |
Family
ID=21843160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13795599A IL137955A (en) | 1998-02-24 | 1999-02-24 | High cross-linked amylose with functional groups as a matrix for delayed release of pharmacological agents |
Country Status (19)
Country | Link |
---|---|
US (2) | US6284273B1 (ko) |
EP (1) | EP1059915B1 (ko) |
JP (1) | JP2002504508A (ko) |
KR (1) | KR100713702B1 (ko) |
CN (1) | CN1298297A (ko) |
AT (1) | ATE277604T1 (ko) |
AU (1) | AU755069B2 (ko) |
BR (1) | BR9908187A (ko) |
CA (1) | CA2321461C (ko) |
CZ (1) | CZ301010B6 (ko) |
DE (1) | DE69920669T2 (ko) |
HU (1) | HU225045B1 (ko) |
IL (1) | IL137955A (ko) |
NO (1) | NO329257B1 (ko) |
NZ (1) | NZ506437A (ko) |
PL (1) | PL192468B1 (ko) |
PT (1) | PT1059915E (ko) |
TR (1) | TR200003014T2 (ko) |
WO (1) | WO1999043305A1 (ko) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100389752C (zh) * | 1978-04-21 | 2008-05-28 | 莱博法姆公司 | 控释组合物 |
IL119660A (en) | 1993-05-10 | 2002-09-12 | Euro Celtique Sa | Controlled release formulation comprising tramadol |
US7022683B1 (en) | 1998-05-13 | 2006-04-04 | Carrington Laboratories, Inc. | Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation |
DE19927688A1 (de) * | 1999-06-17 | 2000-12-21 | Gruenenthal Gmbh | Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
US6607748B1 (en) * | 2000-06-29 | 2003-08-19 | Vincent Lenaerts | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
US6777000B2 (en) | 2001-02-28 | 2004-08-17 | Carrington Laboratories, Inc. | In-situ gel formation of pectin |
EP1387885A1 (en) * | 2001-05-01 | 2004-02-11 | Universite Du Quebec A Montreal | Tridimensional biocompatible support structure for bioartificial organs and uses thereof |
US8487002B2 (en) * | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
MXPA05004410A (es) * | 2002-10-25 | 2005-11-23 | Labopharm Inc | Composiciones de liberacion controlada. |
TWI319713B (en) * | 2002-10-25 | 2010-01-21 | Sustained-release tramadol formulations with 24-hour efficacy | |
US20060172006A1 (en) * | 2003-10-10 | 2006-08-03 | Vincent Lenaerts | Sustained-release tramadol formulations with 24-hour clinical efficacy |
EP1713498A4 (en) * | 2004-02-09 | 2009-07-15 | Transfert Plus Sec | POLYMERIC MATERIAL CONTAINING COMPOSITION AND ITS USES |
CA2491665A1 (fr) * | 2004-12-24 | 2006-06-24 | Louis Cartilier | Formulation de comprime pour liberation soutenue de principe actif |
JP5269595B2 (ja) | 2005-09-09 | 2013-08-21 | アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー | 1日1回投与用トラゾドン組成物 |
CN101309709A (zh) * | 2005-09-21 | 2008-11-19 | 苏尔莫迪克斯公司 | 包含天然生物可降解的多糖的涂层和物品 |
WO2007035865A1 (en) * | 2005-09-21 | 2007-03-29 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
US20090074829A1 (en) * | 2006-03-14 | 2009-03-19 | Masao Tanihara | Novel Heparin Alternative Material and Method for Producing the Same |
CA2590821A1 (en) * | 2007-06-07 | 2008-12-07 | Universite De Montreal | High-amylose sodium carboxymethyl starch sustained release excipient and process for preparing the same |
EP2203166B1 (en) * | 2007-10-16 | 2015-05-06 | Paladin Labs Inc. | Bilayer composition for the sustained release of acetaminophen and tramadol |
CN101161684B (zh) * | 2007-11-23 | 2010-05-19 | 华南理工大学 | 交联羧甲基淀粉的红外线合成方法 |
JP5651818B2 (ja) | 2007-12-17 | 2015-01-14 | パラディン ラブス インコーポレーテッド | 誤用を防止するための放出制御製剤 |
KR20100099307A (ko) * | 2007-12-21 | 2010-09-10 | 아크조 노벨 엔.브이. | 열경화성 폴리머 |
US8936811B2 (en) | 2008-05-07 | 2015-01-20 | Surmodics, Inc. | Device coated with glycogen particles comprising nucleic acid complexes |
WO2010028489A1 (en) * | 2008-09-15 | 2010-03-18 | Labopharm Inc. | Starch-based microparticles for the release of agents disposed therein |
AU2009327312A1 (en) | 2008-12-16 | 2011-08-04 | Labopharm Europe Limited | Misuse preventative, controlled release formulation |
WO2012003968A1 (en) | 2010-07-06 | 2012-01-12 | Grünenthal GmbH | Novel gastro- retentive dosage forms comprising a gaba analog and an opioid |
US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
CA2865917C (en) * | 2011-03-01 | 2020-09-29 | 4413261 Canada Inc. (Spencer Canada) | Two speed monolithic system for controlled release of drugs |
JP6605508B2 (ja) * | 2014-02-27 | 2019-11-13 | ビー‐オーガニック フィルムス コーポレイション | 一重らせんv構造を有する官能化デンプン中に含まれる生物活性剤 |
SG11201704537QA (en) | 2014-12-19 | 2017-07-28 | Baxter Int | Flowable hemostatic composition |
CN104784738B (zh) * | 2015-04-03 | 2016-12-07 | 四川大学 | 一种天然缓释多效医用海绵 |
CN106279453B (zh) | 2015-05-28 | 2019-12-10 | 易媛 | 交联的高分子化合物及其制备方法、水凝胶、水基压裂液和用途 |
CN105536058A (zh) * | 2016-01-22 | 2016-05-04 | 青岛中腾生物技术有限公司 | 一种医用淀粉海绵及其制备方法和用途 |
GB2567493B (en) * | 2017-10-13 | 2019-12-18 | Altus Formulation Inc | Starch-based release modifying excipients and pharmaceutical compositions derived therefrom |
CN111072791A (zh) * | 2019-12-27 | 2020-04-28 | 河南新孚望新材料科技有限公司 | 一种包膜剂用高直链淀粉的制备方法 |
JP7125216B1 (ja) | 2021-03-31 | 2022-08-24 | 長瀬産業株式会社 | 水溶性ポリマーの製造方法、および吸水性樹脂の製造方法 |
JP7348412B2 (ja) * | 2021-03-31 | 2023-09-20 | 長瀬産業株式会社 | 水溶性ポリマーの製造方法、および吸水性樹脂の製造方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4072535A (en) * | 1970-12-28 | 1978-02-07 | A. E. Staley Manufacturing Company | Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules |
US4369308A (en) * | 1981-07-24 | 1983-01-18 | National Starch And Chemical Corporation | Low swelling starches as tablet disintegrants |
JPH0791240B2 (ja) * | 1987-04-01 | 1995-10-04 | 株式会社日本触媒 | 2−ハロエチルアミンハロゲン化水素酸塩の製造方法 |
CA2041774C (en) * | 1990-11-27 | 1994-04-19 | Mircea A. Mateescu | Use of cross-linked amylose as a matrix for the slow release of biologically active compounds |
JPH06271704A (ja) * | 1993-03-22 | 1994-09-27 | Asahi Chem Ind Co Ltd | 水性易燃性組成物 |
US5616343A (en) * | 1993-03-25 | 1997-04-01 | Labopharm, Inc. | Cross-linked amylose as a binder/disintegrant in tablets |
CA2187633A1 (en) * | 1994-04-11 | 1995-10-19 | Douglas R. Chambers | Superabsorbent polymers and products therefrom |
US5830884A (en) * | 1995-01-18 | 1998-11-03 | National Starch And Chemical Investment Holding Corporation | Pharmaceutical products containing thermally-inhibited starches |
US5593503A (en) * | 1995-06-07 | 1997-01-14 | National Starch And Chemical Investment Holding Corporation | Process for producing amylase resistant granular starch |
US5667637A (en) * | 1995-11-03 | 1997-09-16 | Weyerhaeuser Company | Paper and paper-like products including water insoluble fibrous carboxyalkyl cellulose |
CA2173818A1 (fr) * | 1996-04-10 | 1997-10-11 | Francois Chouinard | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
US5879707A (en) * | 1996-10-30 | 1999-03-09 | Universite De Montreal | Substituted amylose as a matrix for sustained drug release |
US5807575A (en) * | 1997-02-14 | 1998-09-15 | Rougier Inc. | Manufacture of cross-linked amylose useful as a excipient for control release of active compounds |
-
1998
- 1998-02-24 US US09/028,385 patent/US6284273B1/en not_active Expired - Lifetime
-
1999
- 1999-02-24 IL IL13795599A patent/IL137955A/en not_active IP Right Cessation
- 1999-02-24 NZ NZ506437A patent/NZ506437A/xx unknown
- 1999-02-24 CN CN99805447A patent/CN1298297A/zh active Pending
- 1999-02-24 TR TR2000/03014T patent/TR200003014T2/xx unknown
- 1999-02-24 AU AU32420/99A patent/AU755069B2/en not_active Ceased
- 1999-02-24 DE DE69920669T patent/DE69920669T2/de not_active Expired - Lifetime
- 1999-02-24 CA CA002321461A patent/CA2321461C/en not_active Expired - Fee Related
- 1999-02-24 KR KR1020007009278A patent/KR100713702B1/ko not_active IP Right Cessation
- 1999-02-24 JP JP2000533104A patent/JP2002504508A/ja active Pending
- 1999-02-24 PL PL342596A patent/PL192468B1/pl not_active IP Right Cessation
- 1999-02-24 AT AT99936029T patent/ATE277604T1/de not_active IP Right Cessation
- 1999-02-24 WO PCT/CA1999/000169 patent/WO1999043305A1/en active IP Right Grant
- 1999-02-24 BR BR9908187-3A patent/BR9908187A/pt not_active Application Discontinuation
- 1999-02-24 EP EP99936029A patent/EP1059915B1/en not_active Expired - Lifetime
- 1999-02-24 HU HU0100818A patent/HU225045B1/hu not_active IP Right Cessation
- 1999-02-24 PT PT99936029T patent/PT1059915E/pt unknown
- 1999-02-24 US US09/257,090 patent/US6419957B1/en not_active Expired - Fee Related
- 1999-02-24 CZ CZ20003097A patent/CZ301010B6/cs not_active IP Right Cessation
-
2000
- 2000-08-23 NO NO20004208A patent/NO329257B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CZ20003097A3 (en) | 2001-06-13 |
HUP0100818A2 (hu) | 2001-08-28 |
BR9908187A (pt) | 2000-10-31 |
CA2321461C (en) | 2008-04-29 |
NO20004208D0 (no) | 2000-08-23 |
HUP0100818A3 (en) | 2001-12-28 |
TR200003014T2 (tr) | 2001-02-21 |
US6284273B1 (en) | 2001-09-04 |
KR100713702B1 (ko) | 2007-05-02 |
EP1059915A1 (en) | 2000-12-20 |
US6419957B1 (en) | 2002-07-16 |
JP2002504508A (ja) | 2002-02-12 |
NO20004208L (no) | 2000-08-23 |
WO1999043305A1 (en) | 1999-09-02 |
KR20010034531A (ko) | 2001-04-25 |
AU755069B2 (en) | 2002-12-05 |
PL342596A1 (en) | 2001-06-18 |
HU225045B1 (en) | 2006-05-29 |
IL137955A0 (en) | 2001-10-31 |
CA2321461A1 (en) | 1999-09-02 |
NZ506437A (en) | 2003-03-28 |
ATE277604T1 (de) | 2004-10-15 |
EP1059915B1 (en) | 2004-09-29 |
AU3242099A (en) | 1999-09-15 |
PL192468B1 (pl) | 2006-10-31 |
PT1059915E (pt) | 2005-02-28 |
DE69920669T2 (de) | 2005-11-03 |
CN1298297A (zh) | 2001-06-06 |
DE69920669D1 (de) | 2004-11-04 |
CZ301010B6 (cs) | 2009-10-14 |
NO329257B1 (no) | 2010-09-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |