TR200003014T2 - Farmasötik maddelerin yavaş salınımı için bir matris olarak işlevsel gruplara sahip olan çapraz-bağlanmış yüksek amiloz nişasta - Google Patents
Farmasötik maddelerin yavaş salınımı için bir matris olarak işlevsel gruplara sahip olan çapraz-bağlanmış yüksek amiloz nişastaInfo
- Publication number
- TR200003014T2 TR200003014T2 TR2000/03014T TR200003014T TR200003014T2 TR 200003014 T2 TR200003014 T2 TR 200003014T2 TR 2000/03014 T TR2000/03014 T TR 2000/03014T TR 200003014 T TR200003014 T TR 200003014T TR 200003014 T2 TR200003014 T2 TR 200003014T2
- Authority
- TR
- Turkey
- Prior art keywords
- high amylose
- cross
- pharmaceuticals
- matrix
- amylose starch
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Mevcut bulus, oral olarak etkin bir farmasötik araci, tercihi bir polisakkaridin veya poliol ve yüksek amiloz nisastanin terapötik bir miktarinin karisimindan olusan bir kati dozaj birimi içeren amilaza karsi dirençli bir kati yavas salinimli oral farmasötik dozaj birimi ile ilgili olup, burada, yüksek amiloz nisastanin çapraz baglamasinin, 100 gr. yüksek amiloz nisasta basina yaklasik olarak 0.1 - 40 gr. çapraz baglama araci ile yerine getirilmesidir. Mevcut bulusun tercih edilen bir kullaniminda, yüksek amiloz nisastanin, esdeger gruplari esdeger olarak baglayan bir islevsel grup-ekleme reaktifi ile degistirilmistir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/028,385 US6284273B1 (en) | 1998-02-24 | 1998-02-24 | Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200003014T2 true TR200003014T2 (tr) | 2001-02-21 |
Family
ID=21843160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/03014T TR200003014T2 (tr) | 1998-02-24 | 1999-02-24 | Farmasötik maddelerin yavaş salınımı için bir matris olarak işlevsel gruplara sahip olan çapraz-bağlanmış yüksek amiloz nişasta |
Country Status (19)
Country | Link |
---|---|
US (2) | US6284273B1 (tr) |
EP (1) | EP1059915B1 (tr) |
JP (1) | JP2002504508A (tr) |
KR (1) | KR100713702B1 (tr) |
CN (1) | CN1298297A (tr) |
AT (1) | ATE277604T1 (tr) |
AU (1) | AU755069B2 (tr) |
BR (1) | BR9908187A (tr) |
CA (1) | CA2321461C (tr) |
CZ (1) | CZ301010B6 (tr) |
DE (1) | DE69920669T2 (tr) |
HU (1) | HU225045B1 (tr) |
IL (1) | IL137955A (tr) |
NO (1) | NO329257B1 (tr) |
NZ (1) | NZ506437A (tr) |
PL (1) | PL192468B1 (tr) |
PT (1) | PT1059915E (tr) |
TR (1) | TR200003014T2 (tr) |
WO (1) | WO1999043305A1 (tr) |
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CN100389752C (zh) * | 1978-04-21 | 2008-05-28 | 莱博法姆公司 | 控释组合物 |
IL119660A (en) | 1993-05-10 | 2002-09-12 | Euro Celtique Sa | Controlled release formulation comprising tramadol |
US7022683B1 (en) | 1998-05-13 | 2006-04-04 | Carrington Laboratories, Inc. | Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation |
DE19927688A1 (de) * | 1999-06-17 | 2000-12-21 | Gruenenthal Gmbh | Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
US6607748B1 (en) * | 2000-06-29 | 2003-08-19 | Vincent Lenaerts | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
US6777000B2 (en) | 2001-02-28 | 2004-08-17 | Carrington Laboratories, Inc. | In-situ gel formation of pectin |
EP1387885A1 (en) * | 2001-05-01 | 2004-02-11 | Universite Du Quebec A Montreal | Tridimensional biocompatible support structure for bioartificial organs and uses thereof |
US8487002B2 (en) * | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
MXPA05004410A (es) * | 2002-10-25 | 2005-11-23 | Labopharm Inc | Composiciones de liberacion controlada. |
TWI319713B (en) * | 2002-10-25 | 2010-01-21 | Sustained-release tramadol formulations with 24-hour efficacy | |
US20060172006A1 (en) * | 2003-10-10 | 2006-08-03 | Vincent Lenaerts | Sustained-release tramadol formulations with 24-hour clinical efficacy |
EP1713498A4 (en) * | 2004-02-09 | 2009-07-15 | Transfert Plus Sec | POLYMERIC MATERIAL CONTAINING COMPOSITION AND ITS USES |
CA2491665A1 (fr) * | 2004-12-24 | 2006-06-24 | Louis Cartilier | Formulation de comprime pour liberation soutenue de principe actif |
JP5269595B2 (ja) | 2005-09-09 | 2013-08-21 | アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー | 1日1回投与用トラゾドン組成物 |
CN101309709A (zh) * | 2005-09-21 | 2008-11-19 | 苏尔莫迪克斯公司 | 包含天然生物可降解的多糖的涂层和物品 |
WO2007035865A1 (en) * | 2005-09-21 | 2007-03-29 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
US20090074829A1 (en) * | 2006-03-14 | 2009-03-19 | Masao Tanihara | Novel Heparin Alternative Material and Method for Producing the Same |
CA2590821A1 (en) * | 2007-06-07 | 2008-12-07 | Universite De Montreal | High-amylose sodium carboxymethyl starch sustained release excipient and process for preparing the same |
EP2203166B1 (en) * | 2007-10-16 | 2015-05-06 | Paladin Labs Inc. | Bilayer composition for the sustained release of acetaminophen and tramadol |
CN101161684B (zh) * | 2007-11-23 | 2010-05-19 | 华南理工大学 | 交联羧甲基淀粉的红外线合成方法 |
JP5651818B2 (ja) | 2007-12-17 | 2015-01-14 | パラディン ラブス インコーポレーテッド | 誤用を防止するための放出制御製剤 |
KR20100099307A (ko) * | 2007-12-21 | 2010-09-10 | 아크조 노벨 엔.브이. | 열경화성 폴리머 |
US8936811B2 (en) | 2008-05-07 | 2015-01-20 | Surmodics, Inc. | Device coated with glycogen particles comprising nucleic acid complexes |
WO2010028489A1 (en) * | 2008-09-15 | 2010-03-18 | Labopharm Inc. | Starch-based microparticles for the release of agents disposed therein |
AU2009327312A1 (en) | 2008-12-16 | 2011-08-04 | Labopharm Europe Limited | Misuse preventative, controlled release formulation |
WO2012003968A1 (en) | 2010-07-06 | 2012-01-12 | Grünenthal GmbH | Novel gastro- retentive dosage forms comprising a gaba analog and an opioid |
US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
CA2865917C (en) * | 2011-03-01 | 2020-09-29 | 4413261 Canada Inc. (Spencer Canada) | Two speed monolithic system for controlled release of drugs |
JP6605508B2 (ja) * | 2014-02-27 | 2019-11-13 | ビー‐オーガニック フィルムス コーポレイション | 一重らせんv構造を有する官能化デンプン中に含まれる生物活性剤 |
SG11201704537QA (en) | 2014-12-19 | 2017-07-28 | Baxter Int | Flowable hemostatic composition |
CN104784738B (zh) * | 2015-04-03 | 2016-12-07 | 四川大学 | 一种天然缓释多效医用海绵 |
CN106279453B (zh) | 2015-05-28 | 2019-12-10 | 易媛 | 交联的高分子化合物及其制备方法、水凝胶、水基压裂液和用途 |
CN105536058A (zh) * | 2016-01-22 | 2016-05-04 | 青岛中腾生物技术有限公司 | 一种医用淀粉海绵及其制备方法和用途 |
GB2567493B (en) * | 2017-10-13 | 2019-12-18 | Altus Formulation Inc | Starch-based release modifying excipients and pharmaceutical compositions derived therefrom |
CN111072791A (zh) * | 2019-12-27 | 2020-04-28 | 河南新孚望新材料科技有限公司 | 一种包膜剂用高直链淀粉的制备方法 |
JP7125216B1 (ja) | 2021-03-31 | 2022-08-24 | 長瀬産業株式会社 | 水溶性ポリマーの製造方法、および吸水性樹脂の製造方法 |
JP7348412B2 (ja) * | 2021-03-31 | 2023-09-20 | 長瀬産業株式会社 | 水溶性ポリマーの製造方法、および吸水性樹脂の製造方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4072535A (en) * | 1970-12-28 | 1978-02-07 | A. E. Staley Manufacturing Company | Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules |
US4369308A (en) * | 1981-07-24 | 1983-01-18 | National Starch And Chemical Corporation | Low swelling starches as tablet disintegrants |
JPH0791240B2 (ja) * | 1987-04-01 | 1995-10-04 | 株式会社日本触媒 | 2−ハロエチルアミンハロゲン化水素酸塩の製造方法 |
CA2041774C (en) * | 1990-11-27 | 1994-04-19 | Mircea A. Mateescu | Use of cross-linked amylose as a matrix for the slow release of biologically active compounds |
JPH06271704A (ja) * | 1993-03-22 | 1994-09-27 | Asahi Chem Ind Co Ltd | 水性易燃性組成物 |
US5616343A (en) * | 1993-03-25 | 1997-04-01 | Labopharm, Inc. | Cross-linked amylose as a binder/disintegrant in tablets |
CA2187633A1 (en) * | 1994-04-11 | 1995-10-19 | Douglas R. Chambers | Superabsorbent polymers and products therefrom |
US5830884A (en) * | 1995-01-18 | 1998-11-03 | National Starch And Chemical Investment Holding Corporation | Pharmaceutical products containing thermally-inhibited starches |
US5593503A (en) * | 1995-06-07 | 1997-01-14 | National Starch And Chemical Investment Holding Corporation | Process for producing amylase resistant granular starch |
US5667637A (en) * | 1995-11-03 | 1997-09-16 | Weyerhaeuser Company | Paper and paper-like products including water insoluble fibrous carboxyalkyl cellulose |
CA2173818A1 (fr) * | 1996-04-10 | 1997-10-11 | Francois Chouinard | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
US5879707A (en) * | 1996-10-30 | 1999-03-09 | Universite De Montreal | Substituted amylose as a matrix for sustained drug release |
US5807575A (en) * | 1997-02-14 | 1998-09-15 | Rougier Inc. | Manufacture of cross-linked amylose useful as a excipient for control release of active compounds |
-
1998
- 1998-02-24 US US09/028,385 patent/US6284273B1/en not_active Expired - Lifetime
-
1999
- 1999-02-24 IL IL13795599A patent/IL137955A/en not_active IP Right Cessation
- 1999-02-24 NZ NZ506437A patent/NZ506437A/xx unknown
- 1999-02-24 CN CN99805447A patent/CN1298297A/zh active Pending
- 1999-02-24 TR TR2000/03014T patent/TR200003014T2/tr unknown
- 1999-02-24 AU AU32420/99A patent/AU755069B2/en not_active Ceased
- 1999-02-24 DE DE69920669T patent/DE69920669T2/de not_active Expired - Lifetime
- 1999-02-24 CA CA002321461A patent/CA2321461C/en not_active Expired - Fee Related
- 1999-02-24 KR KR1020007009278A patent/KR100713702B1/ko not_active IP Right Cessation
- 1999-02-24 JP JP2000533104A patent/JP2002504508A/ja active Pending
- 1999-02-24 PL PL342596A patent/PL192468B1/pl not_active IP Right Cessation
- 1999-02-24 AT AT99936029T patent/ATE277604T1/de not_active IP Right Cessation
- 1999-02-24 WO PCT/CA1999/000169 patent/WO1999043305A1/en active IP Right Grant
- 1999-02-24 BR BR9908187-3A patent/BR9908187A/pt not_active Application Discontinuation
- 1999-02-24 EP EP99936029A patent/EP1059915B1/en not_active Expired - Lifetime
- 1999-02-24 HU HU0100818A patent/HU225045B1/hu not_active IP Right Cessation
- 1999-02-24 PT PT99936029T patent/PT1059915E/pt unknown
- 1999-02-24 US US09/257,090 patent/US6419957B1/en not_active Expired - Fee Related
- 1999-02-24 CZ CZ20003097A patent/CZ301010B6/cs not_active IP Right Cessation
-
2000
- 2000-08-23 NO NO20004208A patent/NO329257B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CZ20003097A3 (en) | 2001-06-13 |
HUP0100818A2 (hu) | 2001-08-28 |
BR9908187A (pt) | 2000-10-31 |
CA2321461C (en) | 2008-04-29 |
NO20004208D0 (no) | 2000-08-23 |
HUP0100818A3 (en) | 2001-12-28 |
US6284273B1 (en) | 2001-09-04 |
KR100713702B1 (ko) | 2007-05-02 |
EP1059915A1 (en) | 2000-12-20 |
US6419957B1 (en) | 2002-07-16 |
JP2002504508A (ja) | 2002-02-12 |
NO20004208L (no) | 2000-08-23 |
WO1999043305A1 (en) | 1999-09-02 |
KR20010034531A (ko) | 2001-04-25 |
AU755069B2 (en) | 2002-12-05 |
PL342596A1 (en) | 2001-06-18 |
HU225045B1 (en) | 2006-05-29 |
IL137955A0 (en) | 2001-10-31 |
CA2321461A1 (en) | 1999-09-02 |
NZ506437A (en) | 2003-03-28 |
ATE277604T1 (de) | 2004-10-15 |
EP1059915B1 (en) | 2004-09-29 |
AU3242099A (en) | 1999-09-15 |
PL192468B1 (pl) | 2006-10-31 |
PT1059915E (pt) | 2005-02-28 |
DE69920669T2 (de) | 2005-11-03 |
CN1298297A (zh) | 2001-06-06 |
DE69920669D1 (de) | 2004-11-04 |
CZ301010B6 (cs) | 2009-10-14 |
NO329257B1 (no) | 2010-09-20 |
IL137955A (en) | 2005-12-18 |
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