IL136721A0 - Novel erythromycin derivatives - Google Patents

Novel erythromycin derivatives

Info

Publication number
IL136721A0
IL136721A0 IL13672198A IL13672198A IL136721A0 IL 136721 A0 IL136721 A0 IL 136721A0 IL 13672198 A IL13672198 A IL 13672198A IL 13672198 A IL13672198 A IL 13672198A IL 136721 A0 IL136721 A0 IL 136721A0
Authority
IL
Israel
Prior art keywords
erythromycin derivatives
novel erythromycin
novel
derivatives
erythromycin
Prior art date
Application number
IL13672198A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of IL136721A0 publication Critical patent/IL136721A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL13672198A 1998-01-02 1998-12-21 Novel erythromycin derivatives IL136721A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7035898P 1998-01-02 1998-01-02
PCT/IB1998/002100 WO1999035157A1 (en) 1998-01-02 1998-12-21 Novel erythromycin derivatives

Publications (1)

Publication Number Publication Date
IL136721A0 true IL136721A0 (en) 2001-06-14

Family

ID=22094819

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13672198A IL136721A0 (en) 1998-01-02 1998-12-21 Novel erythromycin derivatives

Country Status (36)

Country Link
US (1) US6825171B2 (de)
EP (2) EP1642901B1 (de)
JP (1) JP2002500231A (de)
KR (1) KR20010033822A (de)
CN (1) CN1285841A (de)
AP (1) AP1060A (de)
AR (5) AR012764A1 (de)
AT (1) ATE377018T1 (de)
AU (1) AU759019B2 (de)
BG (1) BG104640A (de)
BR (1) BR9812992A (de)
CA (1) CA2317131C (de)
CO (1) CO4970773A1 (de)
CZ (1) CZ20002456A3 (de)
DE (1) DE69838651T9 (de)
DZ (1) DZ2699A1 (de)
EA (1) EA200000600A1 (de)
ES (1) ES2294641T3 (de)
GT (1) GT199800207A (de)
HR (1) HRP20000444A2 (de)
HU (1) HUP0100566A3 (de)
IL (1) IL136721A0 (de)
IS (1) IS5527A (de)
MA (1) MA26588A1 (de)
NO (1) NO20003346L (de)
NZ (1) NZ504987A (de)
OA (1) OA11440A (de)
PA (1) PA8465901A1 (de)
PE (1) PE20000119A1 (de)
PL (1) PL341647A1 (de)
SK (1) SK9772000A3 (de)
TN (1) TNSN98236A1 (de)
UY (2) UY25331A1 (de)
WO (1) WO1999035157A1 (de)
YU (1) YU40900A (de)
ZA (1) ZA9811940B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
GB9814006D0 (en) 1998-06-29 1998-08-26 Biotica Tech Ltd Polyketides and their synthesis
EP1298138B1 (de) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamat und Carbazat Ketolid Antibiotika
EP1749832A3 (de) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamat und Carbazat Ketolid Antibiotika
DE69933897T2 (de) 1998-12-10 2007-03-15 Pfizer Products Inc., Groton Carbamat- und Carbazatketolid-Antibiotika
EP1754700A3 (de) 1999-01-27 2007-05-09 Kosan Biosciences, Inc. synthese von oligoketiden
WO2000044761A2 (en) 1999-01-27 2000-08-03 Pfizer Products Inc. Ketolide antibiotics
US6590083B1 (en) * 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6451768B1 (en) * 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
EP1171447A2 (de) 1999-04-16 2002-01-16 Ortho-McNeil Pharmaceutical, Inc. Antibakterielle ketoliden
MXPA01010524A (es) * 1999-04-16 2002-03-14 Kosan Biosciences Inc Agentes macrolidos anti-infecciosos.
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
CZ20013733A3 (cs) * 1999-05-24 2002-11-13 Pfizer Products Inc. Deriváty 13-methylerythromycinu
ID27331A (id) * 1999-09-29 2001-03-29 Pfizer Prod Inc Pembuatan antibiotik-antibiotik ketolida karbamat
EP1114826A3 (de) * 1999-12-29 2001-10-31 Pfizer Products Inc. Antibakterielle und prokinetische Makroliden
WO2001060833A2 (en) 2000-02-18 2001-08-23 Kosan Biosciences, Inc. Motilide compounds
US20020115621A1 (en) 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
US6472372B1 (en) 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
US6756359B2 (en) 2001-07-03 2004-06-29 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
CN1589277A (zh) 2001-09-17 2005-03-02 奥索-麦克尼尔药品公司 6-o-氨基甲酸酯-11,12-内酯-酮内酯抗菌剂
CN1585775A (zh) 2001-12-05 2005-02-23 奥索-麦克尼尔药品公司 可用作抗菌药的红霉素的6-o-酰基酮内酯衍生物
US6825172B2 (en) 2002-05-31 2004-11-30 Janssen Pharmaceutica, Nv 3-descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents
US7163924B2 (en) 2003-04-25 2007-01-16 Chiron Corporation Ketolide derivatives
CN101120011A (zh) * 2004-12-21 2008-02-06 辉瑞产品公司 大环内酯
JP2009539970A (ja) 2006-06-12 2009-11-19 ラモット アット テル−アビブ ユニバーシティー リミテッド 癌の治療方法
EA201500699A1 (ru) 2012-12-24 2015-12-30 Рамот Эт Тель-Авив Юниверсити Лтд. Агенты для лечения генетических заболеваний, возникающих в результате нонсенс-мутаций, и способы идентификации этих агентов

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US61856A (en) * 1867-02-05 Enos s
US156027A (en) * 1874-10-20 Improvement in loom-shuttles
US61857A (en) * 1867-02-05 Improvement in top-drivers or spinners
US100518A (en) * 1870-03-08 Roland s
US77302A (en) * 1868-04-28 mat son
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
AU1142383A (en) 1982-04-26 1983-11-03 Shakas, P.V. Infant transitional sensory system
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4998097A (en) 1983-07-11 1991-03-05 Square D Company Mechanically operated pressure switch having solid state components
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd 6−0−メチルエリスロマイシンa誘導体
US4585759A (en) * 1985-01-22 1986-04-29 Pfizer Inc. Antibacterial derivatives of a neutral macrolide
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−n−メチルエリスロマイシン誘導体
ES8800986A1 (es) 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4672056A (en) * 1985-11-12 1987-06-09 Abbott Laboratories Erythromycin A derivatives and method of use
JPH0633312B2 (ja) 1986-05-02 1994-05-02 大正製薬株式会社 14−ハイドロキシエリスロマイシン誘導体およびその製造方法
EP0283055B1 (de) * 1987-09-03 1990-08-29 SOUR PLIVA farmaceutska, Kemijska prehrambena i kozmeticka industrija, n.sol.o. 10-Dihydro-10-deoxo-11-azaerythronolid-A-Verbindungen,Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung in Arzneimitteln und in deren Herstellung
GB8726730D0 (en) 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
GB8815967D0 (en) 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
US4934897A (en) 1989-02-23 1990-06-19 J. I. Case Company Pipe-moving apparatus
US5141926A (en) 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US6060234A (en) * 1991-01-17 2000-05-09 Abbott Laboratories Polyketide derivatives and recombinant methods for making same
WO1993013663A1 (en) 1992-01-17 1993-07-22 Abbott Laboratories Method of directing biosynthesis of specific polyketides
US5824513A (en) * 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
JP3286941B2 (ja) * 1991-07-09 2002-05-27 株式会社日立製作所 ダイヤモンド研削砥石のツルーイング法
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
FR2691464B1 (fr) 1992-05-21 1995-06-02 Roussel Uclaf Nouveaux dérivés de la 1-oxa 6-azacyclopentadécane 13,15-dione, leur procédé de préparation et leur application comme médicaments.
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
US6066721A (en) * 1995-07-06 2000-05-23 Stanford University Method to produce novel polyketides
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5486697A (en) 1994-11-14 1996-01-23 California Institute Of Technology Array of micro-machined mass energy micro-filters for charged particles
FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732684B1 (fr) * 1995-04-06 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5801032A (en) 1995-08-03 1998-09-01 Abbott Laboratories Vectors and process for producing high purity 6,12-dideoxyerythromycin A by fermentation
WO1997008266A1 (en) 1995-08-22 1997-03-06 Mobil Oil Corporation Visbreaking process using plastics as co-feed
EP0876388B1 (de) 1995-11-08 2004-02-18 Abbott Laboratories Tricyclische erythromycinderivate
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
US5719272A (en) * 1996-04-02 1998-02-17 Abbott Laboratories 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
US6271255B1 (en) * 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
TR199900006T2 (xx) 1996-07-05 1999-04-21 Biotica Technology Limited Eritromisinler ve bunlar�n haz�rlanmas� i�in i�lem.
ATE296308T1 (de) * 1996-09-04 2005-06-15 Abbott Lab 6-o-substituierte ketoliden mit antibakteriellen wirkung
FR2754821B1 (fr) 1996-10-23 2003-04-04 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
NL1006540C2 (nl) 1997-07-10 1999-01-15 Skf Ind Trading & Dev Elektrische actuator met regelsensor, alsmede schijfrem omvattende een dergelijke actuator.
EP1662423A3 (de) 1997-08-28 2006-08-02 Supersensor (Proprietary) Limited Leseranordnung für ein elektronisches Identifikationssystem
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
ATE275151T1 (de) * 1998-03-03 2004-09-15 Pfizer Prod Inc 3,6-ketal-makrolidantibiotika
US5975370A (en) * 1998-03-16 1999-11-02 Owens-Illinois Closure Inc. Tamper-evident plunger-hold-down attachment for pump dispenser
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
US6262030B1 (en) * 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
WO2000044761A2 (en) 1999-01-27 2000-08-03 Pfizer Products Inc. Ketolide antibiotics
WO2000046404A1 (en) 1999-02-05 2000-08-10 Wrair Walter Reed Army Institute Of Research Method of diagnosing of exposure to toxic agents by measuring distinct pattern in the levels of expression of specific genes
MXPA01010524A (es) * 1999-04-16 2002-03-14 Kosan Biosciences Inc Agentes macrolidos anti-infecciosos.
EP1171447A2 (de) * 1999-04-16 2002-01-16 Ortho-McNeil Pharmaceutical, Inc. Antibakterielle ketoliden
US20020077302A1 (en) 1999-04-23 2002-06-20 Yong-Jin Wu Tricyclic erythromycin derivatives
US20020061857A1 (en) 1999-04-23 2002-05-23 Yong-Jin Wu 9-amino-3-oxo erythromycin derivatives
CZ20013733A3 (cs) 1999-05-24 2002-11-13 Pfizer Products Inc. Deriváty 13-methylerythromycinu
EP1101769A3 (de) * 1999-11-18 2001-10-24 Pfizer Products Inc. Stickstoff-enthaltend Erythromycin-Derivate
US20020061856A1 (en) 2000-04-24 2002-05-23 Yong-Jin Wu Novel tricyclic erythromycin derivatives
JP2005050903A (ja) 2003-07-30 2005-02-24 Toshiba Corp 半導体装置およびその製造方法

Also Published As

Publication number Publication date
HUP0100566A2 (hu) 2001-07-30
AR019789A2 (es) 2002-03-13
NO20003346L (no) 2000-08-29
EP1642901B1 (de) 2007-10-31
OA11440A (en) 2004-04-28
EA200000600A1 (ru) 2001-02-26
CA2317131C (en) 2004-11-02
GT199800207A (es) 2000-06-22
AR019788A2 (es) 2002-03-13
AU1501599A (en) 1999-07-26
EP1044208A1 (de) 2000-10-18
US20040067897A1 (en) 2004-04-08
CO4970773A1 (es) 2000-11-07
CZ20002456A3 (cs) 2001-09-12
ZA9811940B (en) 2000-06-30
WO1999035157A1 (en) 1999-07-15
DE69838651T9 (de) 2008-06-12
UY25587A1 (es) 1999-09-27
ES2294641T3 (es) 2008-04-01
CA2317131A1 (en) 1999-07-15
PA8465901A1 (es) 2000-09-29
DE69838651T2 (de) 2008-03-06
ATE377018T1 (de) 2007-11-15
TNSN98236A1 (fr) 2005-03-15
YU40900A (sh) 2003-01-31
AP1060A (en) 2002-04-23
JP2002500231A (ja) 2002-01-08
AU759019B2 (en) 2003-04-03
KR20010033822A (ko) 2001-04-25
CN1285841A (zh) 2001-02-28
HUP0100566A3 (en) 2003-07-28
US6825171B2 (en) 2004-11-30
UY25331A1 (es) 2000-12-29
EP1642901A1 (de) 2006-04-05
SK9772000A3 (en) 2002-09-10
WO1999035157B1 (en) 1999-10-14
AR019790A2 (es) 2002-03-13
DZ2699A1 (fr) 2003-03-29
AR020016A2 (es) 2002-03-27
DE69838651D1 (de) 2007-12-13
IS5527A (is) 2000-06-09
PE20000119A1 (es) 2000-02-17
AR012764A1 (es) 2000-11-08
NO20003346D0 (no) 2000-06-27
BG104640A (en) 2001-09-28
HRP20000444A2 (en) 2001-04-30
MA26588A1 (fr) 2004-12-20
PL341647A1 (en) 2001-04-23
BR9812992A (pt) 2000-10-17
NZ504987A (en) 2002-11-26
AP9801421A0 (en) 1998-12-31

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