IL136145A0 - Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof - Google Patents
Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereofInfo
- Publication number
- IL136145A0 IL136145A0 IL13614598A IL13614598A IL136145A0 IL 136145 A0 IL136145 A0 IL 136145A0 IL 13614598 A IL13614598 A IL 13614598A IL 13614598 A IL13614598 A IL 13614598A IL 136145 A0 IL136145 A0 IL 136145A0
- Authority
- IL
- Israel
- Prior art keywords
- inhibition
- processes
- preparation
- pharmaceutical compositions
- heterocyclic compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9704404A SE9704404D0 (sv) | 1997-11-28 | 1997-11-28 | New compounds |
PCT/SE1998/002091 WO1999028322A1 (en) | 1997-11-28 | 1998-11-18 | Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL136145A0 true IL136145A0 (en) | 2001-05-20 |
Family
ID=20409181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13614598A IL136145A0 (en) | 1997-11-28 | 1998-11-18 | Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof |
Country Status (33)
Country | Link |
---|---|
US (1) | US6518270B1 (ja) |
EP (1) | EP1042324B1 (ja) |
JP (1) | JP2001525322A (ja) |
KR (1) | KR20010032559A (ja) |
CN (1) | CN1142933C (ja) |
AR (1) | AR016972A1 (ja) |
AT (1) | ATE233263T1 (ja) |
AU (1) | AU752187C (ja) |
BR (1) | BR9814755A (ja) |
CA (1) | CA2311798A1 (ja) |
CZ (1) | CZ292349B6 (ja) |
DE (1) | DE69811735T2 (ja) |
DK (1) | DK1042324T3 (ja) |
EE (1) | EE04060B1 (ja) |
ES (1) | ES2191356T3 (ja) |
HK (1) | HK1030216A1 (ja) |
HU (1) | HUP0100601A3 (ja) |
ID (1) | ID24730A (ja) |
IL (1) | IL136145A0 (ja) |
IS (1) | IS5486A (ja) |
MY (1) | MY121032A (ja) |
NO (1) | NO315704B1 (ja) |
NZ (1) | NZ504355A (ja) |
PL (1) | PL340920A1 (ja) |
PT (1) | PT1042324E (ja) |
RU (1) | RU2241000C2 (ja) |
SE (1) | SE9704404D0 (ja) |
SK (1) | SK283904B6 (ja) |
TR (1) | TR200001530T2 (ja) |
TW (1) | TW515798B (ja) |
UA (1) | UA70932C2 (ja) |
WO (1) | WO1999028322A1 (ja) |
ZA (1) | ZA9810468B (ja) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2324093A (en) | 1996-01-04 | 1998-10-14 | Rican Limited | Helicobacter pylori bacterioferritin |
SE9704404D0 (sv) | 1997-11-28 | 1997-11-28 | Astra Ab | New compounds |
IL148820A0 (en) * | 1999-10-08 | 2002-09-12 | Smithkline Beecham Corp | Fab i inhibitors |
AU2002367773A1 (en) * | 2001-04-06 | 2003-11-03 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
JP2003119140A (ja) * | 2001-08-08 | 2003-04-23 | Sankyo Co Ltd | ピロロピリダジン化合物を含有する医薬 |
KR20050008691A (ko) * | 2002-04-19 | 2005-01-21 | 셀룰러 지노믹스 아이엔씨 | 이미다조[1,2-a]피라진-8-일 아민, 그의 제조방법 및사용방법 |
WO2004022562A1 (en) | 2002-09-09 | 2004-03-18 | Cellular Genomics, Inc. | 6-ARYL-IMIDAZO[1,2-a]PYRAZIN-8-YLAMINES, METHOD OF MAKING, AND METHOD OF USE THEREOF |
AU2003266621A1 (en) * | 2002-09-25 | 2004-04-19 | Sankyo Company, Limited | Medicinal composition for treatment for or prevention of visceral pain |
WO2004029058A1 (ja) * | 2002-09-25 | 2004-04-08 | Sankyo Company, Limited | 血中ガストリン濃度上昇の抑制のための医薬組成物 |
US7790709B2 (en) | 2002-12-06 | 2010-09-07 | Affinium Pharmaceuticals, Inc. | Heterocyclic compounds, methods of making them and their use in therapy |
WO2004072080A1 (en) | 2003-02-10 | 2004-08-26 | Cellular Genomics, Inc. | Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of hsp90 complex activity |
AR043002A1 (es) * | 2003-02-18 | 2005-07-13 | Altana Pharma Ag | Imidazopirazinas 6-substituidos |
WO2004082586A2 (en) * | 2003-03-17 | 2004-09-30 | Affinium Pharmaceuticals, Inc. | Phamaceutical compositions comprising inhibitors of fab i and further antibiotics |
WO2005014599A1 (en) | 2003-06-04 | 2005-02-17 | Cellular Genomics, Inc. | Imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of bruton’s tyrosine kinase by such compounds |
US7393848B2 (en) | 2003-06-30 | 2008-07-01 | Cgi Pharmaceuticals, Inc. | Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds |
US7259164B2 (en) | 2003-08-11 | 2007-08-21 | Cgi Pharmaceuticals, Inc. | Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity |
WO2005041961A1 (en) | 2003-11-03 | 2005-05-12 | Astrazeneca Ab | Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux |
PT1828167E (pt) * | 2004-06-04 | 2014-10-08 | Debiopharm Int Sa | Derivados de acrilamida como agentes antibióticos |
US20070293532A1 (en) * | 2004-07-28 | 2007-12-20 | Takeda Pharmaceutical Compan6Y Limited | Pyrrolo [2,3-C] Pyridine Compound, Process for Producing the Same, and Use |
AU2005268767A1 (en) * | 2004-08-02 | 2006-02-09 | Altana Pharma Ag | 5-substituted 1H-pyrrolo[3,2-B]pyridines |
KR100946220B1 (ko) * | 2004-09-03 | 2010-03-08 | 주식회사유한양행 | 피롤로[3,2-c]피리딘 유도체 및 그의 제조방법 |
KR100958828B1 (ko) * | 2004-09-03 | 2010-05-24 | 주식회사유한양행 | 피롤로[3,2-b]피리딘 유도체 및 그의 제조방법 |
RU2378275C2 (ru) * | 2004-09-03 | 2010-01-10 | Юхан Корпорейшн | ПРОИЗВОДНЫЕ ПИРРОЛО[3,2-c]ПИРИДИНА И СПОСОБ ИХ ПОЛУЧЕНИЯ |
ATE533765T1 (de) | 2004-09-03 | 2011-12-15 | Yuhan Corp | Pyrroloä2,3-cüpyridinderivate und verfahren für deren herstellung |
WO2007024294A2 (en) | 2005-05-03 | 2007-03-01 | Cgi Pharmaceuticals, Inc. | Certain substituted ureas, as modulators of kinase activity |
US7709468B2 (en) | 2005-09-02 | 2010-05-04 | Abbott Laboratories | Imidazo based heterocycles |
WO2007067416A2 (en) * | 2005-12-05 | 2007-06-14 | Affinium Pharmaceuticals, Inc. | Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents |
TW200808802A (en) * | 2006-06-06 | 2008-02-16 | Schering Corp | Imidazopyrazines as protein kinase inhibitors |
EP2687533B1 (en) | 2006-07-20 | 2017-07-19 | Debiopharm International SA | Acrylamide derivatives as FAB I inhibitors |
EP2125802A4 (en) | 2007-02-16 | 2014-08-20 | Debiopharm Int Sa | SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS |
NZ587039A (en) | 2008-02-13 | 2013-01-25 | Gilead Connecticut Inc | 6-aryl-imidazo[1, 2-a]pyrazine derivatives, method of making, and method of use thereof |
AU2009325133B2 (en) | 2008-12-08 | 2016-02-04 | Gilead Connecticut, Inc. | Imidazopyrazine Syk inhibitors |
EP3123864A1 (en) | 2008-12-08 | 2017-02-01 | Gilead Connecticut, Inc. | Imidazopyrazine syk inhibitors |
US8450321B2 (en) | 2008-12-08 | 2013-05-28 | Gilead Connecticut, Inc. | 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor |
AU2011226689B2 (en) | 2010-03-11 | 2016-09-01 | Kronos Bio, Inc. | Imidazopyridines Syk inhibitors |
RS58898B1 (sr) | 2012-06-19 | 2019-08-30 | Debiopharm Int Sa | Prolek derivati (e)-n-metil-n-((3-metilbenzofuran-2-il)metil)-3-(7-okso-5,6,7,8-tetrahidro-1,8-naftiridin-3-il)akrilamida |
KR101810798B1 (ko) | 2013-07-30 | 2017-12-19 | 질레드 코네티컷 인코포레이티드 | Syk 억제제의 다형체 |
UA115815C2 (uk) | 2013-07-30 | 2017-12-26 | Гіліад Коннектікут, Інк. | Склад на основі інгібіторів syk |
MX2016007311A (es) | 2013-12-04 | 2016-09-07 | Gilead Sciences Inc | Metodos para tratar canceres. |
GB201321738D0 (en) * | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic Agents |
TWI662037B (zh) | 2013-12-23 | 2019-06-11 | 美商基利科學股份有限公司 | 脾酪胺酸激酶抑制劑 |
US9290505B2 (en) | 2013-12-23 | 2016-03-22 | Gilead Sciences, Inc. | Substituted imidazo[1,2-a]pyrazines as Syk inhibitors |
NZ726365A (en) | 2014-07-14 | 2018-06-29 | Gilead Sciences Inc | Combinations for treating cancers |
LT3419628T (lt) | 2016-02-26 | 2021-01-25 | Debiopharm International Sa | Medikamentas diabetinėms pėdų infekcijoms gydyti |
AU2018321264A1 (en) | 2017-08-25 | 2020-02-27 | Kronos Bio, Inc. | Polymorphs of Syk inhibitors |
CA3130848A1 (en) | 2019-02-22 | 2020-08-27 | Kronos Bio, Inc. | Solid forms of condensed pyrazines as syk inhibitors |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4507294A (en) * | 1982-03-08 | 1985-03-26 | Schering Corp. | Imidazo[1,2-a]pyrazines |
EP0068378B1 (en) * | 1981-06-26 | 1986-03-05 | Schering Corporation | Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them |
US4725601A (en) * | 1985-06-04 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers |
IL97931A0 (en) | 1990-04-27 | 1992-06-21 | Byk Gulden Lomberg Chem Fab | Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
US5041442A (en) * | 1990-07-31 | 1991-08-20 | Syntex (U.S.A.) Inc. | Pyrrolo(1,2-a)pyrazines as inhibitors of gastric acid secretion |
AU8712191A (en) | 1990-10-15 | 1992-05-20 | Byk Gulden Lomberg Chemische Fabrik Gmbh | New diazines |
WO1993008190A1 (de) * | 1991-10-25 | 1993-04-29 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pyrrolo-pyridazine mit magen- und darmschutzwirkungen |
WO1995019980A1 (fr) * | 1994-01-19 | 1995-07-27 | Sankyo Company, Limited | Derive de pyrrolopyridazine |
SE9602286D0 (sv) | 1996-06-10 | 1996-06-10 | Astra Ab | New compounds |
SE9700661D0 (sv) | 1997-02-25 | 1997-02-25 | Astra Ab | New compounds |
SE9704404D0 (sv) | 1997-11-28 | 1997-11-28 | Astra Ab | New compounds |
-
1997
- 1997-11-28 SE SE9704404A patent/SE9704404D0/xx unknown
-
1998
- 1998-11-16 AR ARP980105799A patent/AR016972A1/es unknown
- 1998-11-16 ZA ZA9810468A patent/ZA9810468B/xx unknown
- 1998-11-16 TW TW087118942A patent/TW515798B/zh active
- 1998-11-17 MY MYPI98005216A patent/MY121032A/en unknown
- 1998-11-18 KR KR1020007005804A patent/KR20010032559A/ko not_active Application Discontinuation
- 1998-11-18 CA CA002311798A patent/CA2311798A1/en not_active Abandoned
- 1998-11-18 JP JP2000523214A patent/JP2001525322A/ja active Pending
- 1998-11-18 US US09/194,823 patent/US6518270B1/en not_active Expired - Lifetime
- 1998-11-18 BR BR9814755-2A patent/BR9814755A/pt not_active Application Discontinuation
- 1998-11-18 PL PL98340920A patent/PL340920A1/xx not_active Application Discontinuation
- 1998-11-18 TR TR2000/01530T patent/TR200001530T2/xx unknown
- 1998-11-18 RU RU2000113729/04A patent/RU2241000C2/ru not_active IP Right Cessation
- 1998-11-18 PT PT98957270T patent/PT1042324E/pt unknown
- 1998-11-18 AT AT98957270T patent/ATE233263T1/de not_active IP Right Cessation
- 1998-11-18 CZ CZ20001947A patent/CZ292349B6/cs not_active IP Right Cessation
- 1998-11-18 IL IL13614598A patent/IL136145A0/xx unknown
- 1998-11-18 WO PCT/SE1998/002091 patent/WO1999028322A1/en not_active Application Discontinuation
- 1998-11-18 UA UA2000052801A patent/UA70932C2/uk unknown
- 1998-11-18 EP EP98957270A patent/EP1042324B1/en not_active Expired - Lifetime
- 1998-11-18 CN CNB98813344XA patent/CN1142933C/zh not_active Expired - Fee Related
- 1998-11-18 NZ NZ504355A patent/NZ504355A/en unknown
- 1998-11-18 DE DE69811735T patent/DE69811735T2/de not_active Expired - Fee Related
- 1998-11-18 ID IDW20000987A patent/ID24730A/id unknown
- 1998-11-18 EE EEP200000315A patent/EE04060B1/xx not_active IP Right Cessation
- 1998-11-18 ES ES98957270T patent/ES2191356T3/es not_active Expired - Lifetime
- 1998-11-18 SK SK674-2000A patent/SK283904B6/sk unknown
- 1998-11-18 DK DK98957270T patent/DK1042324T3/da active
- 1998-11-18 AU AU13565/99A patent/AU752187C/en not_active Ceased
- 1998-11-18 HU HU0100601A patent/HUP0100601A3/hu unknown
-
2000
- 2000-05-10 IS IS5486A patent/IS5486A/is unknown
- 2000-05-26 NO NO20002721A patent/NO315704B1/no unknown
-
2001
- 2001-02-16 HK HK01101145A patent/HK1030216A1/xx not_active IP Right Cessation
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