ATE533765T1 - Pyrroloä2,3-cüpyridinderivate und verfahren für deren herstellung - Google Patents

Pyrroloä2,3-cüpyridinderivate und verfahren für deren herstellung

Info

Publication number
ATE533765T1
ATE533765T1 AT05808813T AT05808813T ATE533765T1 AT E533765 T1 ATE533765 T1 AT E533765T1 AT 05808813 T AT05808813 T AT 05808813T AT 05808813 T AT05808813 T AT 05808813T AT E533765 T1 ATE533765 T1 AT E533765T1
Authority
AT
Austria
Prior art keywords
derivatives
pyrroloä2
cüpyridine
production
pharmaceutically acceptable
Prior art date
Application number
AT05808813T
Other languages
English (en)
Inventor
Jae-Gyu Kim
Byung-Nak Ahn
Hyouk-Woo Lee
Suk-Won Yoon
Young-Ae Yoon
Dong-Hoon Kim
Chan-Sun Park
Seok-Hee Han
Myung-Hun Cha
Heui-Il Kang
Ryong Choi
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Application granted granted Critical
Publication of ATE533765T1 publication Critical patent/ATE533765T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05808813T 2004-09-03 2005-09-03 Pyrroloä2,3-cüpyridinderivate und verfahren für deren herstellung ATE533765T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20040070533 2004-09-03
PCT/KR2005/002927 WO2006025716A1 (en) 2004-09-03 2005-09-03 Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof

Publications (1)

Publication Number Publication Date
ATE533765T1 true ATE533765T1 (de) 2011-12-15

Family

ID=36000318

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05808813T ATE533765T1 (de) 2004-09-03 2005-09-03 Pyrroloä2,3-cüpyridinderivate und verfahren für deren herstellung

Country Status (16)

Country Link
US (2) US7662832B2 (de)
EP (1) EP1784404B1 (de)
JP (1) JP4898683B2 (de)
KR (3) KR100958830B1 (de)
CN (1) CN101018789B (de)
AT (1) ATE533765T1 (de)
AU (1) AU2005280740B2 (de)
BR (1) BRPI0514925A (de)
CA (1) CA2579087C (de)
DK (1) DK1784404T3 (de)
ES (1) ES2373672T3 (de)
MX (1) MX2007002324A (de)
PL (1) PL1784404T3 (de)
PT (1) PT1784404E (de)
RU (1) RU2385320C2 (de)
WO (2) WO2006025716A1 (de)

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DK1784404T3 (da) * 2004-09-03 2012-02-13 Yuhan Corp Pyrrolo[2,3-c]pyridinderivater samt fremgangsmåder til deres fremstilling
WO2006042102A2 (en) * 2004-10-05 2006-04-20 Neurogen Corporation Pyrrolo-pyridine, pyrrolo-pyrimidine and related heterocyclic compounds
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CN102875549B (zh) * 2012-09-14 2015-11-04 浙江大学 7-芳（甲）胺基-5-胺基-6-氮杂吲哚衍生物及制备与用途
US9045477B2 (en) * 2013-03-15 2015-06-02 Epizyme, Inc. Substituted 6,5-fused bicyclic heteroaryl compounds
KR101657597B1 (ko) * 2013-05-08 2016-09-19 주식회사유한양행 피롤로[2,3-c]피리딘 유도체 또는 이의 약학적으로 허용가능한 염의 제조방법
WO2014189238A1 (en) * 2013-05-20 2014-11-27 Yuhan Corporation Process for the preparation of pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof
BG111544A (bg) 2013-07-29 2015-01-30 Николай Цветков Субституирани бензамидни производни като in vitro mao-b инхибитори
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KR102129842B1 (ko) 2013-10-02 2020-07-06 주식회사 대웅제약 술포닐인돌 유도체 및 이의 제조방법
WO2015125858A1 (ja) * 2014-02-24 2015-08-27 日本曹達株式会社 ヘテロアリール化合物およびその用途
CN105440016B (zh) * 2014-08-11 2018-08-31 江苏柯菲平医药股份有限公司 吲哚、氮杂吲哚类衍生物、其制备方法及其在医药上的应用
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KR101613245B1 (ko) 2015-04-27 2016-04-18 주식회사 대웅제약 신규의 4-메톡시 피롤 유도체 또는 이의 염 및 이를 포함하는 약학 조성물
EP3693369A3 (de) * 2016-04-15 2020-09-09 AbbVie Inc. Bromdomäneninhibitoren
KR101777971B1 (ko) 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
CN108164455A (zh) * 2017-03-23 2018-06-15 广东众生药业股份有限公司 马来酸非尼拉敏的合成方法
KR102233456B1 (ko) * 2017-05-31 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
CN110117284B (zh) * 2018-02-06 2021-11-19 江苏奥赛康药业有限公司 含氮杂环类化合物及其制备方法和用途
WO2019236884A1 (en) 2018-06-07 2019-12-12 Disarm Therapeutics, Inc. Inhibitors of sarm1
CA3123215C (en) 2018-12-19 2024-04-02 Disarm Therapeutics, Inc. Inhibitors of sarm1 in combination with neuroprotective agents
CN112300169B (zh) * 2019-07-26 2022-03-04 上海美迪西生物医药股份有限公司 吡咯并吡唑类衍生物、其制备方法及其在医药上的应用
CN112300170B (zh) * 2019-07-26 2022-01-21 上海美迪西生物医药股份有限公司 吡咯并吡唑类衍生物、其制备方法及其在医药上的应用
CN120208865A (zh) * 2025-03-11 2025-06-27 宿迁海德医药化工有限公司 一种2-氯-3-肼基吡啶的合成方法
CN121005705A (zh) * 2025-10-28 2025-11-25 齐鲁理工学院 一种利用共轭二烯官能化异腈与次甲基异腈反应制备吡咯并吡啶衍生物的方法

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Also Published As

Publication number Publication date
CN101018789A (zh) 2007-08-15
KR20060051005A (ko) 2006-05-19
PT1784404E (pt) 2011-12-09
KR100958829B1 (ko) 2010-05-25
RU2007112110A (ru) 2008-10-10
EP1784404A1 (de) 2007-05-16
US20100069430A1 (en) 2010-03-18
MX2007002324A (es) 2007-05-11
RU2385320C2 (ru) 2010-03-27
BRPI0514925A (pt) 2008-07-01
CA2579087A1 (en) 2006-03-09
EP1784404B1 (de) 2011-11-16
US20070219230A1 (en) 2007-09-20
JP2008511621A (ja) 2008-04-17
CN101018789B (zh) 2010-09-08
JP4898683B2 (ja) 2012-03-21
PL1784404T3 (pl) 2012-04-30
EP1784404A4 (de) 2009-09-09
CA2579087C (en) 2012-05-01
US8188114B2 (en) 2012-05-29
AU2005280740B2 (en) 2011-04-28
DK1784404T3 (da) 2012-02-13
ES2373672T3 (es) 2012-02-07
WO2006025716A1 (en) 2006-03-09
HK1105979A1 (en) 2008-02-29
WO2006025717A1 (en) 2006-03-09
AU2005280740A1 (en) 2006-03-09
KR101049068B1 (ko) 2011-07-15
KR20060051006A (ko) 2006-05-19
US7662832B2 (en) 2010-02-16
KR100958830B1 (ko) 2010-05-24
KR20100039325A (ko) 2010-04-15

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