MX2007002324A - Derivados de pirrolo[2-3-c]piridina y procesos para la preparacion de los mismos. - Google Patents

Derivados de pirrolo[2-3-c]piridina y procesos para la preparacion de los mismos.

Info

Publication number
MX2007002324A
MX2007002324A MX2007002324A MX2007002324A MX2007002324A MX 2007002324 A MX2007002324 A MX 2007002324A MX 2007002324 A MX2007002324 A MX 2007002324A MX 2007002324 A MX2007002324 A MX 2007002324A MX 2007002324 A MX2007002324 A MX 2007002324A
Authority
MX
Mexico
Prior art keywords
pyrrolo
pyridine derivatives
processes
preparation
pharmaceutically acceptable
Prior art date
Application number
MX2007002324A
Other languages
English (en)
Inventor
Jae-Gyu Kim
Byung-Nak Ahn
Hyouk-Woo Lee
Suk-Won Yoon
Young-Ae Yoon
Myung-Hun Cha
Dong-Hoon Kim
Heui Il Kang
Choi Ryong
Chan-Sun Park
Seok-Hee Han
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of MX2007002324A publication Critical patent/MX2007002324A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion proporciona derivados de pirrolo[3,2-c]piridina novedosos o sales farmaceuticamente aceptable de los mismos, procesos para la preparacion de los mismos, y composiciones que comprende los mismos. Los derivados de pirrolo[3,2-c]piridina o sales farmaceuticamente aceptables de los mismos de la presente invencion tienen excelente efectos y procesos de inhibicion de bombeo de proton, la habilidad para lograr un efecto de inhibicion de bombeo de proton reversible.
MX2007002324A 2004-09-03 2005-09-03 Derivados de pirrolo[2-3-c]piridina y procesos para la preparacion de los mismos. MX2007002324A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20040070533 2004-09-03
PCT/KR2005/002927 WO2006025716A1 (en) 2004-09-03 2005-09-03 Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof

Publications (1)

Publication Number Publication Date
MX2007002324A true MX2007002324A (es) 2007-05-11

Family

ID=36000318

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007002324A MX2007002324A (es) 2004-09-03 2005-09-03 Derivados de pirrolo[2-3-c]piridina y procesos para la preparacion de los mismos.

Country Status (17)

Country Link
US (2) US7662832B2 (es)
EP (1) EP1784404B1 (es)
JP (1) JP4898683B2 (es)
KR (3) KR100958829B1 (es)
CN (1) CN101018789B (es)
AT (1) ATE533765T1 (es)
AU (1) AU2005280740B2 (es)
BR (1) BRPI0514925A (es)
CA (1) CA2579087C (es)
DK (1) DK1784404T3 (es)
ES (1) ES2373672T3 (es)
HK (1) HK1105979A1 (es)
MX (1) MX2007002324A (es)
PL (1) PL1784404T3 (es)
PT (1) PT1784404E (es)
RU (1) RU2385320C2 (es)
WO (2) WO2006025717A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102152809B1 (ko) † 2004-07-28 2020-09-07 다케다 야쿠힌 고교 가부시키가이샤 피롤로〔2,3-ｃ〕피리딘 화합물, 그 제조 방법 및 용도
CA2579087C (en) * 2004-09-03 2012-05-01 Yuhan Corporation Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof
US7906528B2 (en) * 2004-10-05 2011-03-15 Novartis International Pharmaceutical Ltd. Pyrrolo-pyridine, pyrrolo-pyrimidine and related heterocyclic compounds
GB0525143D0 (en) * 2005-12-09 2006-01-18 Novartis Ag Organic compounds
EP2452680B1 (en) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
CN102875549B (zh) * 2012-09-14 2015-11-04 浙江大学 7-芳（甲）胺基-5-胺基-6-氮杂吲哚衍生物及制备与用途
US9045477B2 (en) * 2013-03-15 2015-06-02 Epizyme, Inc. Substituted 6,5-fused bicyclic heteroaryl compounds
WO2014182033A1 (en) * 2013-05-08 2014-11-13 Yuhan Corporation Process for the preparation of pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof
KR101657599B1 (ko) * 2013-05-20 2016-09-19 주식회사유한양행 피롤로[2,3-c]피리딘 유도체 또는 이의 약학적으로 허용가능한 염의 제조방법
BG111544A (bg) 2013-07-29 2015-01-30 Николай Цветков Субституирани бензамидни производни като in vitro mao-b инхибитори
KR102084185B1 (ko) 2013-08-29 2020-03-04 주식회사 대웅제약 테트라히드로사이클로펜타피롤 유도체 및 이의 제조방법
KR102129842B1 (ko) 2013-10-02 2020-07-06 주식회사 대웅제약 술포닐인돌 유도체 및 이의 제조방법
WO2015125858A1 (ja) * 2014-02-24 2015-08-27 日本曹達株式会社 ヘテロアリール化合物およびその用途
CN105440016B (zh) * 2014-08-11 2018-08-31 江苏柯菲平医药股份有限公司 吲哚、氮杂吲哚类衍生物、其制备方法及其在医药上的应用
MA41850A (fr) 2015-03-31 2018-02-06 Takeda Pharmaceuticals Co Nouvelles utilisations pharmaceutiques
KR101613245B1 (ko) 2015-04-27 2016-04-18 주식회사 대웅제약 신규의 4-메톡시 피롤 유도체 또는 이의 염 및 이를 포함하는 약학 조성물
DK3442972T3 (da) * 2016-04-15 2020-04-27 Abbvie Inc Bromdomænehæmmere
KR101777971B1 (ko) 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
CN108164455A (zh) * 2017-03-23 2018-06-15 广东众生药业股份有限公司 马来酸非尼拉敏的合成方法
KR102233456B1 (ko) * 2017-05-31 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
CN110117284B (zh) * 2018-02-06 2021-11-19 江苏奥赛康药业有限公司 含氮杂环类化合物及其制备方法和用途
JP7212781B2 (ja) 2018-12-19 2023-01-25 ディスアーム セラピューティクス， インコーポレイテッド 神経保護剤と組み合わせたｓａｒｍ１の阻害剤
CN112300169B (zh) * 2019-07-26 2022-03-04 上海美迪西生物医药股份有限公司 吡咯并吡唑类衍生物、其制备方法及其在医药上的应用
CN112300170B (zh) * 2019-07-26 2022-01-21 上海美迪西生物医药股份有限公司 吡咯并吡唑类衍生物、其制备方法及其在医药上的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3269604D1 (en) 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4428962A (en) * 1981-10-30 1984-01-31 Schering Corporation Indoles in treatment of peptic ulcers
JPH0611670A (ja) * 1992-06-25 1994-01-21 Hitachi Ltd 光強度変調素子および光強度変調器
JP3465827B2 (ja) 1993-02-24 2003-11-10 株式会社日清製粉グループ本社 アザインドール誘導体およびこれを有効成分とする抗潰瘍薬
JP3143571B2 (ja) * 1994-01-19 2001-03-07 三共株式会社 ピロロピリダジン誘導体
US5750531A (en) 1994-08-13 1998-05-12 Yuhan Corporation Pyrimidine derivatives and processes for the preparation thereof
GB2298199A (en) * 1995-02-21 1996-08-28 Merck Sharp & Dohme Synthesis of azaindoles
FR2732969B1 (fr) * 1995-04-14 1997-05-16 Adir Nouveaux composes pyridiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
EE04677B1 (et) 1998-09-23 2006-08-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahdropridoeetrid, nende kasutamine ja ravim
US20040110785A1 (en) * 2001-02-02 2004-06-10 Tao Wang Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
US7361671B2 (en) * 2001-11-15 2008-04-22 The Institute For Pharmaceutical Discovery, Inc. Substituted heteroarylalkanoic acids
TW200301251A (en) 2001-12-20 2003-07-01 Wyeth Corp Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
RU2006147278A (ru) * 2004-06-09 2008-07-20 Глэксо Груп Лимитед (GB) Производные пирролопиридина
KR102152809B1 (ko) * 2004-07-28 2020-09-07 다케다 야쿠힌 고교 가부시키가이샤 피롤로〔2,3-ｃ〕피리딘 화합물, 그 제조 방법 및 용도
CA2579087C (en) * 2004-09-03 2012-05-01 Yuhan Corporation Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof

Also Published As

Publication number Publication date
BRPI0514925A (pt) 2008-07-01
ES2373672T3 (es) 2012-02-07
KR101049068B1 (ko) 2011-07-15
US8188114B2 (en) 2012-05-29
PT1784404E (pt) 2011-12-09
KR100958830B1 (ko) 2010-05-24
WO2006025717A1 (en) 2006-03-09
EP1784404A4 (en) 2009-09-09
EP1784404B1 (en) 2011-11-16
KR20100039325A (ko) 2010-04-15
JP4898683B2 (ja) 2012-03-21
ATE533765T1 (de) 2011-12-15
CA2579087A1 (en) 2006-03-09
AU2005280740B2 (en) 2011-04-28
KR20060051006A (ko) 2006-05-19
US7662832B2 (en) 2010-02-16
US20070219230A1 (en) 2007-09-20
HK1105979A1 (en) 2008-02-29
PL1784404T3 (pl) 2012-04-30
CA2579087C (en) 2012-05-01
EP1784404A1 (en) 2007-05-16
AU2005280740A1 (en) 2006-03-09
CN101018789A (zh) 2007-08-15
KR20060051005A (ko) 2006-05-19
JP2008511621A (ja) 2008-04-17
DK1784404T3 (da) 2012-02-13
RU2385320C2 (ru) 2010-03-27
WO2006025716A1 (en) 2006-03-09
RU2007112110A (ru) 2008-10-10
KR100958829B1 (ko) 2010-05-25
US20100069430A1 (en) 2010-03-18
CN101018789B (zh) 2010-09-08

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