IL134165A0 - Analgesic compositions comprising anti-epileptic compounds and methods of using same - Google Patents
Analgesic compositions comprising anti-epileptic compounds and methods of using sameInfo
- Publication number
- IL134165A0 IL134165A0 IL13416598A IL13416598A IL134165A0 IL 134165 A0 IL134165 A0 IL 134165A0 IL 13416598 A IL13416598 A IL 13416598A IL 13416598 A IL13416598 A IL 13416598A IL 134165 A0 IL134165 A0 IL 134165A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- pain
- same
- compounds
- novel combinations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5820797P | 1997-09-08 | 1997-09-08 | |
PCT/US1998/017083 WO1999012537A1 (fr) | 1997-09-08 | 1998-08-18 | Compositions analgesiques comprenant des composes anticonvulsivants et leur mode d'utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
IL134165A0 true IL134165A0 (en) | 2001-04-30 |
Family
ID=22015361
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13416598A IL134165A0 (en) | 1997-09-08 | 1998-08-18 | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
IL185345A IL185345A0 (en) | 1997-09-08 | 2007-08-16 | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL185345A IL185345A0 (en) | 1997-09-08 | 2007-08-16 | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
Country Status (20)
Country | Link |
---|---|
US (3) | US6593368B2 (fr) |
EP (1) | EP1011658B1 (fr) |
JP (1) | JP3782935B2 (fr) |
KR (1) | KR100537707B1 (fr) |
AT (1) | ATE311867T1 (fr) |
AU (1) | AU750578B2 (fr) |
BR (1) | BR9812162A (fr) |
CA (1) | CA2296336C (fr) |
CU (1) | CU23226B7 (fr) |
DE (1) | DE69832712T2 (fr) |
DK (1) | DK1011658T3 (fr) |
ES (1) | ES2253825T3 (fr) |
HU (1) | HU226165B1 (fr) |
IL (2) | IL134165A0 (fr) |
IS (1) | IS5362A (fr) |
NO (1) | NO324122B1 (fr) |
NZ (1) | NZ502671A (fr) |
PL (1) | PL339142A1 (fr) |
WO (1) | WO1999012537A1 (fr) |
ZA (1) | ZA988159B (fr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9710536A (pt) | 1996-07-24 | 1999-08-17 | Warner Lambert Co | Isobutilgaba e seus derivados para o tratamento da dor |
IL134165A0 (en) | 1997-09-08 | 2001-04-30 | Warner Lambert Co | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
ID28277A (id) | 1998-07-09 | 2001-05-10 | Warner Lambert Co | Komposisi-komposisi yang terdiri dari analog-analog gaba dan kaffein |
AU3216600A (en) * | 1999-03-10 | 2000-09-28 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
AU4334900A (en) | 1999-04-09 | 2000-11-14 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
WO2001000191A2 (fr) * | 1999-06-23 | 2001-01-04 | Warner-Lambert Company | Utilisation de fosphenytoine pour le traitement de douleur neuropathique aigue |
ATE284223T1 (de) * | 1999-08-20 | 2004-12-15 | Ortho Mcneil Pharm Inc | Zusammensetzung enthaltend ein tramadol und ein antikonvulsives arzneimittel |
ES2253579T3 (es) | 2001-09-03 | 2006-06-01 | Newron Pharmaceuticals S.P.A. | Composicion farmaceutica que comprende gabapentina o un analogo suyo y una alfa-aminoamida y su uso analgesico. |
US7612112B2 (en) | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
TWI312285B (en) * | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
US20070184104A1 (en) * | 2001-10-25 | 2007-08-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
US20060159743A1 (en) * | 2001-10-25 | 2006-07-20 | Depomed, Inc. | Methods of treating non-nociceptive pain states with gastric retentive gabapentin |
US6730667B2 (en) * | 2001-11-26 | 2004-05-04 | William R. Deagle | Iontophoresis disc pain blocker |
JP4428053B2 (ja) | 2002-02-05 | 2010-03-10 | 味の素株式会社 | ガバペンチン若しくはプレガバリンおよびn型カルシウムチャンネル拮抗剤を含有する医薬組成物 |
CA2476438A1 (fr) * | 2002-02-22 | 2003-08-28 | Warner-Lambert Company Llc | Combinaisons d'un ligand alpha-2-delta avec un inhibiteur selectif de cyclooxygenase-2 |
KR20070091049A (ko) * | 2002-12-13 | 2007-09-06 | 워너-램버트 캄파니 엘엘씨 | 하부요로증상을 치료하기 위한 알파-2-델타 리간드 |
FR2862875B1 (fr) * | 2003-12-02 | 2006-04-07 | Mathey Acoustique Service | Preparation pharmaceutique pour le traitement des acouphenes |
CN101080224B (zh) * | 2004-11-16 | 2011-03-30 | 利默里克神经科学股份有限公司 | 治疗疼痛的组合物及其应用 |
US20070087977A1 (en) * | 2004-11-16 | 2007-04-19 | Wendye Robbins | Methods and compositions for treating pain |
KR20080034205A (ko) * | 2005-09-19 | 2008-04-18 | 테바 파마슈티컬 인더스트리즈 리미티드 | (s)-프레가발린의 신규한 합성을 위한 주요 중간체인 키랄3-카르바모일메틸-5-메틸 헥산산 |
MXPA05011735A (es) * | 2005-11-01 | 2007-04-30 | Leopoldo Espinosa Abdala | Composiciones farmaceuticas que comprenden combinaciones de analgesicos y anticonvulsivantes para el tratamiento del dolor agudo y cronico. |
US20090176882A1 (en) * | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
UA94979C2 (uk) * | 2006-12-22 | 2011-06-25 | Рекордати Айеленд Лимитед | КОМБІНОВАНА ТЕРАПІЯ ПОРУШЕНЬ НИЖНІХ СЕЧОВИВІДНИХ ШЛЯХІВ ЛІГАНДАМИ α2δ І НПЗП |
MX2007006091A (es) * | 2007-05-21 | 2009-02-25 | World Trade Imp Export Wtie Ag | Composicion farmaceutica que comprende la combinacion de un agente antiinflamatorio no esteroideo y un agente anticonvulsionante. |
JP5592790B2 (ja) * | 2007-08-06 | 2014-09-17 | トリニティ ラボラトリーズ インコーポレイテッド | 慢性疼痛およびニューロパシーに関連する疼痛を治療する医薬組成物 |
SG157299A1 (en) | 2008-05-09 | 2009-12-29 | Agency Science Tech & Res | Diagnosis and treatment of kawasaki disease |
EP2297090A1 (fr) * | 2008-06-23 | 2011-03-23 | Teva Pharmaceutical Industries Ltd. | Synthèse enzymatique stéréosélective de l ester (s) ou (r)-isobutylglutarique |
FR2934267B1 (fr) * | 2008-07-23 | 2010-08-13 | Pharmaleads | Derives aminophosphiniques utiles dans le traitement de la douleur |
US20100190752A1 (en) | 2008-09-05 | 2010-07-29 | Gruenenthal Gmbh | Pharmaceutical Combination |
CA2738468A1 (fr) | 2008-09-27 | 2010-04-01 | Taraxos Inc. | Formulations topiques pour le traitement d'une neuropathie |
KR101810246B1 (ko) | 2008-10-08 | 2017-12-18 | 엑스진 파마슈티컬 인크. | Gaba 접합체 및 그의 사용 방법 |
PL2599487T3 (pl) * | 2010-07-30 | 2015-09-30 | Toray Industries | Środek terapeutyczny lub środek profilaktyczny przeciwko bólowi neuropatycznemu |
WO2013076339A1 (fr) * | 2011-11-22 | 2013-05-30 | Servicio Andaluz De Salud | Compositions et préparations combinées pour le traitement de la fibromyalgie |
US9545415B2 (en) * | 2012-01-06 | 2017-01-17 | Skyview Enterprise Ltd. | Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation |
FR2998892B1 (fr) | 2012-12-04 | 2015-01-02 | Pf Medicament | Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments |
MX2015016589A (es) | 2015-12-02 | 2017-06-01 | Samuel CHAIT AUERBACH Jaime | Composicion oral veterinaria con gabapentina. |
KR102631399B1 (ko) * | 2018-03-30 | 2024-02-01 | 씨지인바이츠 주식회사 | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
CA3079509C (fr) | 2018-07-04 | 2020-11-03 | AMEZCUA AMEZCUA, Federico | Combinaison medicamenteuse synergique de l'enantiomere actif (s)-ketorolac et de gabapentine pour le traitement de la douleur neuropathique |
MX2019008467A (es) * | 2019-07-16 | 2019-11-07 | Federico Amezcua Amezcua | Combinacion sinergica de s-ketorolaco y pregabalina en una composicion farmaceutica para el tratamiento del dolor neuropatico. |
US11147780B2 (en) * | 2020-02-24 | 2021-10-19 | Algia Pharma, Llc | Multidrug pain management package |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
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BE634102A (fr) * | ||||
DE1963925C3 (de) * | 1969-12-20 | 1975-07-10 | Desitin-Werk, Carl Klinke Gmbh, 2000 Hamburg | Verfahren zur Herstellung von N hoch 3-Carbalkoxyderivaten des 5,5-Diphenylhydantoins |
US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
JPS54110334A (en) * | 1978-02-16 | 1979-08-29 | Fuji Chem Ind Co Ltd | Novel compounded anodyne and antiiinflammatory agent |
JPS61221121A (ja) * | 1985-03-27 | 1986-10-01 | Nitto Electric Ind Co Ltd | テ−プ製剤 |
US4694010A (en) * | 1985-08-16 | 1987-09-15 | New York University | Anticonvulsant compositions and method |
JPH02502546A (ja) * | 1987-12-22 | 1990-08-16 | ファーカニー、ジョン ダブリュ | 抗ひきつけ剤組成物および方法のためのデキストロルファン相乗的協力剤 |
US6197819B1 (en) * | 1990-11-27 | 2001-03-06 | Northwestern University | Gamma amino butyric acid analogs and optical isomers |
GB9108362D0 (en) * | 1991-04-18 | 1991-06-05 | Radoslavov Alexander | A pharmaceutical composition suitable for alleviation of headaches,migraine and other painful conditions |
DE69330949T2 (de) | 1992-05-20 | 2002-04-04 | Univ Northwestern | Gaba und l-glutaminsaüre analoga zur behandlung der epilepsie |
US5234929A (en) * | 1992-07-20 | 1993-08-10 | William Chelen | Method of treating motion sickness with anticonvulsants and antitussive agents |
JPH06100468A (ja) * | 1992-09-25 | 1994-04-12 | Kibun Food Chemifa Co Ltd | 徐放性組成物 |
US5321012A (en) | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
JPH06227969A (ja) * | 1993-02-02 | 1994-08-16 | Masayasu Sugihara | 薬品の腸溶性改善方法およびそれにより得られた薬品組成物 |
US5420270A (en) | 1993-10-07 | 1995-05-30 | G. D. Searle & Co. | Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
US5352638A (en) | 1994-02-22 | 1994-10-04 | Corning Incorporated | Nickel aluminosilicate glass-ceramics |
ES2211916T3 (es) | 1994-09-02 | 2004-07-16 | Virginia Commonwealth University | Composicion para aliviar dolor, que contiene un analgesico no narcortico y un potenciador de analgesia. |
CN1046199C (zh) * | 1994-12-13 | 1999-11-10 | 凌吉安 | 复方消炎止痛霜剂 |
BR9710536A (pt) * | 1996-07-24 | 1999-08-17 | Warner Lambert Co | Isobutilgaba e seus derivados para o tratamento da dor |
DE69733081T2 (de) * | 1996-08-23 | 2006-05-11 | Endo Pharmaceuticals Inc. (n.d.Ges.d. Staates Delaware) | Antikonvulsive mitteln enthaltende zubereitung zur behandlung von neuropathischen schmerzen |
US6057373A (en) | 1997-05-22 | 2000-05-02 | Synchroneuron, Llc | Methods of treating tardive dyskinesia and other movement disorders using NMDA receptor antagonists |
US6127418A (en) * | 1997-08-20 | 2000-10-03 | Warner-Lambert Company | GABA analogs to prevent and treat gastrointestinal damage |
AU8668598A (en) | 1997-08-20 | 1999-03-08 | University Of Oklahoma, The | Gaba analogs to prevent and treat gastrointestinal damage |
IL134165A0 (en) | 1997-09-08 | 2001-04-30 | Warner Lambert Co | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
AU3216600A (en) | 1999-03-10 | 2000-09-28 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
-
1998
- 1998-08-18 IL IL13416598A patent/IL134165A0/xx unknown
- 1998-08-18 AU AU91987/98A patent/AU750578B2/en not_active Ceased
- 1998-08-18 KR KR10-2000-7002400A patent/KR100537707B1/ko not_active IP Right Cessation
- 1998-08-18 DK DK98944449T patent/DK1011658T3/da active
- 1998-08-18 CA CA002296336A patent/CA2296336C/fr not_active Expired - Fee Related
- 1998-08-18 PL PL98339142A patent/PL339142A1/xx not_active Application Discontinuation
- 1998-08-18 EP EP98944449A patent/EP1011658B1/fr not_active Expired - Lifetime
- 1998-08-18 ES ES98944449T patent/ES2253825T3/es not_active Expired - Lifetime
- 1998-08-18 JP JP2000510435A patent/JP3782935B2/ja not_active Expired - Fee Related
- 1998-08-18 WO PCT/US1998/017083 patent/WO1999012537A1/fr active Application Filing
- 1998-08-18 HU HU0003705A patent/HU226165B1/hu not_active IP Right Cessation
- 1998-08-18 BR BR9812162-6A patent/BR9812162A/pt not_active Application Discontinuation
- 1998-08-18 US US09/463,116 patent/US6593368B2/en not_active Expired - Fee Related
- 1998-08-18 NZ NZ502671A patent/NZ502671A/xx unknown
- 1998-08-18 AT AT98944449T patent/ATE311867T1/de not_active IP Right Cessation
- 1998-08-18 DE DE69832712T patent/DE69832712T2/de not_active Expired - Fee Related
- 1998-09-07 ZA ZA988159A patent/ZA988159B/xx unknown
-
2000
- 2000-01-25 IS IS5362A patent/IS5362A/is unknown
- 2000-03-03 CU CU20000051A patent/CU23226B7/es not_active IP Right Cessation
- 2000-03-07 NO NO20001175A patent/NO324122B1/no not_active IP Right Cessation
-
2002
- 2002-02-13 US US10/075,929 patent/US6942876B2/en not_active Expired - Fee Related
-
2003
- 2003-04-04 US US10/407,888 patent/US20030176505A1/en not_active Abandoned
-
2007
- 2007-08-16 IL IL185345A patent/IL185345A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20020115705A1 (en) | 2002-08-22 |
EP1011658B1 (fr) | 2005-12-07 |
AU9198798A (en) | 1999-03-29 |
US20030176505A1 (en) | 2003-09-18 |
ZA988159B (en) | 1999-03-11 |
CA2296336A1 (fr) | 1999-03-18 |
DE69832712T2 (de) | 2006-06-22 |
CA2296336C (fr) | 2004-04-20 |
JP3782935B2 (ja) | 2006-06-07 |
AU750578B2 (en) | 2002-07-25 |
KR20010023745A (ko) | 2001-03-26 |
NO20001175L (no) | 2000-03-07 |
ES2253825T3 (es) | 2006-06-01 |
WO1999012537A1 (fr) | 1999-03-18 |
HU226165B1 (en) | 2008-05-28 |
ATE311867T1 (de) | 2005-12-15 |
HUP0003705A2 (hu) | 2001-04-28 |
BR9812162A (pt) | 2000-07-18 |
PL339142A1 (en) | 2000-12-04 |
EP1011658A1 (fr) | 2000-06-28 |
US20030065028A1 (en) | 2003-04-03 |
HUP0003705A3 (en) | 2002-01-28 |
JP2001515859A (ja) | 2001-09-25 |
US6593368B2 (en) | 2003-07-15 |
NO324122B1 (no) | 2007-08-27 |
KR100537707B1 (ko) | 2005-12-20 |
NZ502671A (en) | 2003-01-31 |
DE69832712D1 (de) | 2006-01-12 |
US6942876B2 (en) | 2005-09-13 |
IS5362A (is) | 2000-01-25 |
NO20001175D0 (no) | 2000-03-07 |
IL185345A0 (en) | 2008-01-06 |
CU23226B7 (es) | 2007-09-26 |
DK1011658T3 (da) | 2006-04-03 |
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