IL104212A - Pharmaceutical compositions containing amidino derivatives, some such compounds and process for their preparation - Google Patents

Pharmaceutical compositions containing amidino derivatives, some such compounds and process for their preparation

Info

Publication number
IL104212A
IL104212A IL104212A IL10421292A IL104212A IL 104212 A IL104212 A IL 104212A IL 104212 A IL104212 A IL 104212A IL 10421292 A IL10421292 A IL 10421292A IL 104212 A IL104212 A IL 104212A
Authority
IL
Israel
Prior art keywords
group
formula
pharmaceutically acceptable
optionally
6alkyl
Prior art date
Application number
IL104212A
Other languages
English (en)
Other versions
IL104212A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL104212A0 publication Critical patent/IL104212A0/xx
Publication of IL104212A publication Critical patent/IL104212A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL104212A 1991-12-24 1992-12-23 Pharmaceutical compositions containing amidino derivatives, some such compounds and process for their preparation IL104212A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919127376A GB9127376D0 (en) 1991-12-24 1991-12-24 Amidino derivatives

Publications (2)

Publication Number Publication Date
IL104212A0 IL104212A0 (en) 1993-05-13
IL104212A true IL104212A (en) 1998-02-22

Family

ID=10706815

Family Applications (1)

Application Number Title Priority Date Filing Date
IL104212A IL104212A (en) 1991-12-24 1992-12-23 Pharmaceutical compositions containing amidino derivatives, some such compounds and process for their preparation

Country Status (20)

Country Link
US (1) US5863931A (ru)
EP (1) EP0618898B1 (ru)
JP (1) JP3171850B2 (ru)
AT (1) ATE178588T1 (ru)
AU (1) AU669345B2 (ru)
CA (1) CA2126327C (ru)
CY (1) CY2197B1 (ru)
DE (1) DE69228879T2 (ru)
DK (1) DK0618898T3 (ru)
ES (1) ES2130247T3 (ru)
GB (1) GB9127376D0 (ru)
GR (1) GR3030492T3 (ru)
HU (1) HU217618B (ru)
IL (1) IL104212A (ru)
MY (1) MY109421A (ru)
NZ (1) NZ246202A (ru)
RU (1) RU2130014C1 (ru)
TW (1) TW255881B (ru)
WO (1) WO1993013055A1 (ru)
ZA (1) ZA9210018B (ru)

Families Citing this family (119)

* Cited by examiner, † Cited by third party
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CA2126327A1 (en) 1993-07-08
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NZ246202A (en) 1996-05-28
EP0618898A1 (en) 1994-10-12
WO1993013055A1 (en) 1993-07-08
HUT70502A (en) 1995-10-30
ES2130247T3 (es) 1999-07-01
TW255881B (ru) 1995-09-01
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US5863931A (en) 1999-01-26
MY109421A (en) 1997-01-31
ZA9210018B (en) 1994-06-23
JPH07502512A (ja) 1995-03-16
DE69228879D1 (de) 1999-05-12
ATE178588T1 (de) 1999-04-15
HU9401848D0 (en) 1994-09-28
AU3169293A (en) 1993-07-28
RU2130014C1 (ru) 1999-05-10
JP3171850B2 (ja) 2001-06-04
CY2197B1 (en) 2002-11-08
RU94031155A (ru) 1996-04-20
DE69228879T2 (de) 1999-08-26
GB9127376D0 (en) 1992-02-19
HU217618B (hu) 2000-03-28
EP0618898B1 (en) 1999-04-07
GR3030492T3 (en) 1999-10-29
CA2126327C (en) 2005-05-17

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