IL101944A - תכשיר לכה לצפורניים המכיל טרבינאפין - Google Patents

תכשיר לכה לצפורניים המכיל טרבינאפין

Info

Publication number
IL101944A
IL101944A IL10194492A IL10194492A IL101944A IL 101944 A IL101944 A IL 101944A IL 10194492 A IL10194492 A IL 10194492A IL 10194492 A IL10194492 A IL 10194492A IL 101944 A IL101944 A IL 101944A
Authority
IL
Israel
Prior art keywords
compound
formula
polymeric film
film former
formulation according
Prior art date
Application number
IL10194492A
Other languages
English (en)
Other versions
IL101944A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919111210A external-priority patent/GB9111210D0/en
Priority claimed from GB929204472A external-priority patent/GB9204472D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL101944A0 publication Critical patent/IL101944A0/xx
Publication of IL101944A publication Critical patent/IL101944A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00—Manicure or pedicure preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00—Manicure or pedicure preparations
    • A61Q3/02—Nail coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL10194492A 1991-05-23 1992-05-21 תכשיר לכה לצפורניים המכיל טרבינאפין IL101944A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919111210A GB9111210D0 (en) 1991-05-23 1991-05-23 Pharmaceutical composition
GB929204472A GB9204472D0 (en) 1992-03-02 1992-03-02 Pharmaceutical composition

Publications (2)

Publication Number Publication Date
IL101944A0 IL101944A0 (en) 1992-12-30
IL101944A true IL101944A (he) 1998-07-15

Family

ID=26298942

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10194492A IL101944A (he) 1991-05-23 1992-05-21 תכשיר לכה לצפורניים המכיל טרבינאפין

Country Status (31)

Country Link
US (3) US5866105A (he)
EP (1) EP0515312B1 (he)
JP (1) JP3527749B2 (he)
KR (1) KR100367150B1 (he)
AT (1) AT400518B (he)
AU (1) AU642090B2 (he)
CA (1) CA2069153C (he)
CH (1) CH683237A5 (he)
CY (1) CY2070B1 (he)
CZ (1) CZ284232B6 (he)
DE (1) DE4215677B4 (he)
DK (1) DK0515312T3 (he)
ES (1) ES2091441T3 (he)
FI (1) FI109333B (he)
FR (1) FR2676647B1 (he)
GB (1) GB2256138B (he)
GR (1) GR3021551T3 (he)
HK (1) HK1000242A1 (he)
HU (1) HU219480B (he)
IE (1) IE66476B1 (he)
IL (1) IL101944A (he)
IT (1) IT1254571B (he)
LU (1) LU88117A1 (he)
MX (1) MX9202407A (he)
NO (1) NO300084B1 (he)
NZ (1) NZ242849A (he)
PH (1) PH31205A (he)
RO (1) RO112081B1 (he)
RU (1) RU2110257C1 (he)
SK (1) SK281130B6 (he)
ZA (1) ZA923765B (he)

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HU219480B (hu) * 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására
US5464610A (en) * 1992-10-15 1995-11-07 Schering-Plough Healthcare Products, Inc. Method for treating onychomycosis
DK128494A (da) * 1994-11-08 1996-05-09 Edel K Seidenschnur Behandling af keratinøse og psoriatiske sygdomstilstande med neglelak indeholdende vitamin D metabolit, eller derivat, og/eller vitamin A derivat
DE19643831A1 (de) 1996-10-30 1998-05-07 Hoechst Ag Verwendung von 1-Hydroxy-2-pyridonen zur Behandlung von schwer therapierbaren Schleimhauterkrankungen
CA2248977A1 (en) * 1996-03-16 1997-09-25 Hoechst Aktiengesellschaft Topical formulations for the treatment of nail psoriasis
US20040039030A1 (en) * 1996-09-27 2004-02-26 Hoechst Akeengesellschaft Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis
DE19639817A1 (de) 1996-09-27 1998-04-02 Hoechst Ag Verwendung von 1-Hydroxy-2-pyridonen zur Behandlung von Hautinfektionen
DE19639816A1 (de) 1996-09-27 1998-04-02 Hoechst Ag Antimykotische Mittel mit hoher Wirkstofffreisetzung
RO118174B1 (ro) * 1997-08-21 2003-03-28 Aventis Pharma Deutschland Gmbh Lac de unghii şi utilizarea acestuia
US6605751B1 (en) * 1997-11-14 2003-08-12 Acrymed Silver-containing compositions, devices and methods for making
US6727401B1 (en) 1998-02-12 2004-04-27 Watson Pharmaceuticals, Inc. Pressure sensitive adhesive matrix patch for the treatment of onychomycosis
ATE269067T1 (de) * 1998-04-17 2004-07-15 Bertek Pharm Inc Topische formulierungen zur behandlung von nagel pilzerkrankungen
WO2000054732A1 (en) * 1999-03-16 2000-09-21 Mark Yezbick A fingernail coating composition
US6403063B1 (en) 1999-07-26 2002-06-11 Kenneth I. Sawyer Method of treating nail fungus
DE19949517A1 (de) * 1999-10-14 2001-04-19 Henkel Kgaa Festigende Haarreinigungsmittel
AU2742401A (en) 1999-12-30 2001-07-16 Acrymed Methods and compositions for improved delivery devices
DE10011081A1 (de) * 2000-03-09 2001-09-13 Aventis Pharma Gmbh Antiinfektive Wirkstoffkombinationen und ihre Verwendung zur topischen Behandlung von Pilzerkrankungen der Fuß- und Fingernägel
GB0014448D0 (en) * 2000-06-13 2000-08-09 Novartis Ag Organic compounds
DE10035991A1 (de) 2000-07-24 2002-02-14 Polichem Sa Nagellackzusammensetzung
GB0019283D0 (en) * 2000-08-04 2000-09-27 Novartis Ag Organic compounds
JP4803511B2 (ja) * 2000-08-25 2011-10-26 株式会社ポーラファルマ 抗真菌医薬組成物
GB0103046D0 (en) 2001-02-07 2001-03-21 Novartis Ag Organic Compounds
US6585963B1 (en) * 2001-02-15 2003-07-01 Watson Pharmaceuticals, Inc. Nail compositions and methods of administering same
US6878365B2 (en) * 2001-03-10 2005-04-12 James Edward Brehove Topical application for treating toenail fungus
US7244703B2 (en) * 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
IL160552A0 (en) * 2001-09-04 2004-07-25 Trommsdorff Gmbh & Co Kg Plaster for the treatment of dysfunctions and disorders of nails, comprising sertaconazole
US6921529B2 (en) * 2002-07-29 2005-07-26 Joseph C. Maley Treatment modality and method for fungal nail infection
CN1678277B (zh) 2002-07-29 2010-05-05 艾克里麦德公司 治疗皮肤病的方法和组合物
US20030049307A1 (en) * 2002-08-15 2003-03-13 Gyurik Robert J. Pharmaceutical composition
EP1534070A4 (en) * 2002-08-20 2008-07-09 Doren M Pinnel METHODS FOR TREATING FUNGAL INFECTIONS
US20040126343A1 (en) * 2002-12-26 2004-07-01 Garshowitz Solomon David Nail drug delivery
ATE432087T1 (de) 2003-03-21 2009-06-15 Nexmed Holdings Inc Antimykotischer nagellack und anwendungsverfahren
ES2348303T3 (es) 2003-12-08 2010-12-02 Cpex Pharmaceuticals, Inc. Composiciones farmacauticas y procedimientos de tratamiento con insulina.
EP1781098B1 (en) * 2004-07-30 2015-10-07 Avent, Inc. Antimicrobial devices and compositions
CN102894009B (zh) * 2004-07-30 2015-08-19 阿文特公司 抗微生物的银组合物
US8361553B2 (en) 2004-07-30 2013-01-29 Kimberly-Clark Worldwide, Inc. Methods and compositions for metal nanoparticle treated surfaces
EP1809264B1 (en) * 2004-09-20 2016-04-13 Avent, Inc. Antimicrobial amorphous compositions
FR2878157B1 (fr) * 2004-11-23 2007-03-02 Durlin France Sa Composition de vernis a base de solvant a base de solvant d'origine vegetale
US20060165747A1 (en) * 2005-01-24 2006-07-27 David Rolf Antifungal composition, method and kit for topically treating onychomycosis
BRPI0616765A2 (pt) * 2005-09-29 2011-06-28 Novartis Ag composição antifúngica tópica adaptada para tratar uma infecção fúngica da pele, método para tratar uma infecção da pele por dermatófito, método para tratar infecção da pele e processo para a fabricação de uma composição farmacêutica tópica
CN101262848B (zh) * 2005-09-29 2011-05-11 诺瓦提斯公司 抗真菌组合物
RU2008131498A (ru) * 2006-01-02 2010-02-10 Тлт Медикал Лтд. (Ch) Фармацевтическая композиция для лечения заболевний ногтей
US8293965B2 (en) * 2006-04-28 2012-10-23 Kimberly-Clark Worldwide, Inc. Antimicrobial site dressings
JP2010519288A (ja) * 2007-02-21 2010-06-03 パワー ペイパー リミテッド イオン導入法のためのテルビナフィン製剤
US20090082469A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched terbinafine
GB0720716D0 (en) * 2007-10-23 2007-12-05 York Pharma Plc Novel formulation
CA2743774C (en) * 2008-11-24 2017-11-28 Kimberly-Clark Worldwide, Inc. Antimicrobial laminate constructs
WO2010069519A1 (en) * 2008-12-18 2010-06-24 Merz Pharma Gmbh & Co. Kgaa Topical compositions comprising at least one active ingredient poorly soluble in water and biopolymers such as hyaluronic acid with a pka-value between 5-7
EP2395839B1 (en) * 2009-02-13 2014-05-07 Topica Pharmaceuticals, Inc Anti-fungal formulation
FR2942716B1 (fr) * 2009-03-06 2011-04-15 Galderma Res & Dev Methode de solubilisation d'agent antifongique et compositions a haute concentration en agent antifongique applicables sur l'ongle
EP2408299B1 (en) * 2009-03-20 2013-10-23 Stiefel Laboratories, Inc. Fatty acid monoglyceride compositions
EP2900210A1 (en) * 2012-07-06 2015-08-05 Leo Pharma A/S A topical composition comprising a film-forming polymer for delivering an active ingredient to skin
US8697753B1 (en) 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis

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GB2002795B (en) * 1977-07-15 1982-03-17 Mallinckrodt Inc Nail enamel compositions their preparation and use
DE19975055I1 (de) * 1979-08-22 2000-01-27 Novartis Ag Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwending als Arzneimittel
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EP0247142B1 (en) * 1985-11-04 1993-01-07 Owen/Galderma Laboratories Inc. Film-forming, pharmaceutical vehicles for application of medicaments to nails, pharmaceutical compositions based on those vehicles, and methods of using same
DE3544983A1 (de) * 1985-12-19 1987-06-25 Hoechst Ag Antimykotisch wirksamer nagellack
US4782059A (en) * 1986-09-29 1988-11-01 Merck & Co., Inc. Method of controlling mycotic infections and compositions therefor
HU200914B (en) * 1987-03-09 1990-09-28 Horvath Gyoengyi Lengyelne Process for producing new medical dosage unit suitable for local treatment of fungus infection of nails
DE3720147A1 (de) * 1987-06-16 1988-12-29 Hoechst Ag Antimykotisch wirksamer nagellack sowie verfahren zu dessen herstellung
LU86924A1 (fr) * 1987-06-19 1989-03-08 Oreal Vernis a ongles anhydres
US4920109A (en) * 1988-04-18 1990-04-24 Merck & Co., Inc. Antifungal compositions and method of controlling mycotic infections
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US5116603A (en) * 1989-01-31 1992-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Oral antifungal preventative, and method of use
CA2008775C (en) * 1989-02-24 1998-12-22 Alberto Ferro Nail lacquer
FR2646603B1 (fr) * 1989-05-03 1991-07-12 Oreal Composition nettoyante
CA2020888A1 (en) * 1989-07-27 1991-01-28 Philippe Guerry Substituted aminoalkoxybenzene derivatives
FR2666962B1 (fr) 1990-09-26 1996-06-14 Oreal Composition antifongique sous forme de spray sec.
FR2673537B1 (fr) * 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
HU223343B1 (hu) 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
HU219480B (hu) * 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására

Also Published As

Publication number Publication date
DE4215677A1 (de) 1992-11-26
US6319509B1 (en) 2001-11-20
GB9210974D0 (en) 1992-07-08
HUT62467A (en) 1993-05-28
NO922006D0 (no) 1992-05-21
GB2256138A (en) 1992-12-02
EP0515312B1 (en) 1996-08-14
PH31205A (en) 1998-05-05
HU219480B (hu) 2001-04-28
FI922316A0 (fi) 1992-05-21
SK281130B6 (sk) 2000-12-11
NO300084B1 (no) 1997-04-07
CH683237A5 (de) 1994-02-15
GB2256138B (en) 1995-01-11
FI922316A (fi) 1992-11-24
IE921670A1 (en) 1992-12-02
ATA105892A (de) 1995-06-15
ES2091441T3 (es) 1996-11-01
KR920021140A (ko) 1992-12-18
AU642090B2 (en) 1993-10-07
CA2069153A1 (en) 1992-11-24
DE4215677B4 (de) 2008-01-17
EP0515312A2 (en) 1992-11-25
AT400518B (de) 1996-01-25
LU88117A1 (fr) 1993-12-06
MX9202407A (es) 1992-11-01
ITRM920381A1 (it) 1993-11-22
JPH05148136A (ja) 1993-06-15
IE66476B1 (en) 1995-12-27
KR100367150B1 (ko) 2003-03-03
AU1705892A (en) 1992-11-26
IT1254571B (it) 1995-09-25
DK0515312T3 (da) 1996-11-18
NO922006L (no) 1992-11-24
FR2676647A1 (fr) 1992-11-27
CS153292A3 (en) 1992-12-16
EP0515312A3 (en) 1993-04-14
CZ284232B6 (cs) 1998-09-16
RO112081B1 (ro) 1997-05-30
GR3021551T3 (en) 1997-02-28
US6214360B1 (en) 2001-04-10
FI109333B (fi) 2002-07-15
HK1000242A1 (en) 1998-02-13
ZA923765B (en) 1993-11-22
JP3527749B2 (ja) 2004-05-17
CA2069153C (en) 2002-12-17
US5866105A (en) 1999-02-02
NZ242849A (en) 1993-09-27
HU9201548D0 (en) 1992-07-28
IL101944A0 (en) 1992-12-30
ITRM920381A0 (it) 1992-05-22
FR2676647B1 (fr) 1995-05-12
CY2070B1 (en) 1998-09-11
RU2110257C1 (ru) 1998-05-10

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