IE42208B1 - 3-amino-indazlecarboxylic acid derivatives,process for their preparation and their use as medicaments - Google Patents

3-amino-indazlecarboxylic acid derivatives,process for their preparation and their use as medicaments

Info

Publication number
IE42208B1
IE42208B1 IE2714/75A IE271475A IE42208B1 IE 42208 B1 IE42208 B1 IE 42208B1 IE 2714/75 A IE2714/75 A IE 2714/75A IE 271475 A IE271475 A IE 271475A IE 42208 B1 IE42208 B1 IE 42208B1
Authority
IE
Ireland
Prior art keywords
amino
compound
indazole
formula
salt
Prior art date
Application number
IE2714/75A
Other languages
English (en)
Other versions
IE42208L (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IE42208L publication Critical patent/IE42208L/xx
Publication of IE42208B1 publication Critical patent/IE42208B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IE2714/75A 1974-12-13 1975-12-12 3-amino-indazlecarboxylic acid derivatives,process for their preparation and their use as medicaments IE42208B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2458965A DE2458965C3 (de) 1974-12-13 1974-12-13 3-Amino-indazol-N-carbonsäure-Derivate, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
IE42208L IE42208L (en) 1976-06-13
IE42208B1 true IE42208B1 (en) 1980-06-18

Family

ID=5933305

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2714/75A IE42208B1 (en) 1974-12-13 1975-12-12 3-amino-indazlecarboxylic acid derivatives,process for their preparation and their use as medicaments

Country Status (27)

Country Link
US (1) US4051252A (show.php)
JP (1) JPS5182266A (show.php)
AT (1) AT343653B (show.php)
BE (1) BE836528A (show.php)
CA (1) CA1059523A (show.php)
CH (1) CH622250A5 (show.php)
CS (1) CS189731B2 (show.php)
DD (1) DD125484A5 (show.php)
DE (1) DE2458965C3 (show.php)
DK (1) DK137082C (show.php)
ES (1) ES443429A1 (show.php)
FI (1) FI753493A7 (show.php)
FR (1) FR2293928A1 (show.php)
GB (1) GB1490306A (show.php)
HK (1) HK52580A (show.php)
HU (1) HU173557B (show.php)
IE (1) IE42208B1 (show.php)
IL (1) IL48642A (show.php)
KE (1) KE3078A (show.php)
LU (1) LU73993A1 (show.php)
NL (1) NL7514521A (show.php)
NO (1) NO145382C (show.php)
PL (1) PL99858B1 (show.php)
SE (1) SE419645B (show.php)
SU (1) SU604487A3 (show.php)
YU (1) YU315275A (show.php)
ZA (1) ZA757777B (show.php)

Families Citing this family (39)

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US4431657A (en) * 1982-05-24 1984-02-14 Ayerst, Mckenna & Harrison Inc. Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives
KR20010086657A (ko) * 2000-03-02 2001-09-15 성재갑 아미노인다졸 유도체 및 이를 함유하는 싸이클린 의존키나아제 저해제 조성물
US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6660731B2 (en) 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
WO2002022604A1 (en) * 2000-09-15 2002-03-21 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
ZA200301701B (en) * 2000-09-15 2004-03-01 Vertex Pharma Pyrazole compounds useful as protein kinase inhibitors.
SI1318997T1 (sl) * 2000-09-15 2006-12-31 Vertex Pharma Pirazolne spojine, uporabne kot inhibitorji protein-kinaze
CA2432131C (en) * 2000-12-21 2008-07-08 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
KR100406634B1 (ko) * 2001-03-12 2003-11-20 주식회사 엘지생명과학 3,5-디아미노인다졸 유도체, 그의 제조방법 및 사이클린의존성 키나아제 저해제로서의 그의 용도
BR0212841A (pt) 2001-09-26 2004-08-03 Pharmacia Italia Spa Derivado ativo de aminoindazole como inibidores de cinase, processo para sua preparação e composições farmacêuticas que os contém
JP4656838B2 (ja) * 2002-02-06 2011-03-23 バーテックス ファーマシューティカルズ インコーポレイテッド Ｇｓｋ−３の阻害剤として有用なヘテロアリール化合物
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
US20040009981A1 (en) 2002-03-15 2004-01-15 David Bebbington Compositions useful as inhibitors of protein kinases
JP4751063B2 (ja) 2002-05-17 2011-08-17 ファイザー イタリア ソシエタ ア レスポンサビリタ リミタータ キナーゼ阻害剤として活性のアミノインダゾール誘導体、それらの調製方法、及びそれらを含む薬学的組成物
MY141867A (en) 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
NZ538426A (en) 2002-08-02 2007-05-31 Vertex Pharma Pyrazole compositions useful as inhibitors of glycogen synthase kinase-3 (GSK-3)
US7199119B2 (en) * 2002-10-31 2007-04-03 Amgen Inc. Antiinflammation agents
US7601718B2 (en) 2003-02-06 2009-10-13 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
AU2004297235A1 (en) * 2003-12-04 2005-06-23 Vertex Pharmaceuticals Incorporated Quinoxalines useful as inhibitors of protein kinases
DE102004005172A1 (de) * 2004-02-02 2005-08-18 Aventis Pharma Deutschland Gmbh Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
EP1917259B1 (en) 2005-08-18 2012-01-25 Vertex Pharmaceuticals Incorporated Pyrazine kinase inhibitors
JP5249770B2 (ja) 2005-11-03 2013-07-31 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼインヒビターとして有用なアミノピリジン
NZ571705A (en) * 2006-04-14 2012-03-30 Abbott Lab Process for the preparation of indazolyl ureas that inhibit vanilloid subtype 1 (VR1) receptors
JP2010509231A (ja) 2006-11-02 2010-03-25 バーテックス ファーマシューティカルズ インコーポレイテッド プロテインキナーゼの阻害剤として有用なアミノピリジンおよびアミノピリミジン
NZ577768A (en) 2006-12-19 2012-01-12 Vertex Pharma Aminopyrimidines useful as inhibitors of protein kinases
MX2009009590A (es) 2007-03-09 2009-11-10 Vertex Pharma Aminopirimidinas utiles como inhibidores de proteinas cinasas.
AU2008226461A1 (en) 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyridines useful as inhibitors of protein kinases
ES2374335T3 (es) 2007-03-09 2012-02-15 Vertex Pharmaceuticals Incorporated Aminopirimidinas útiles como inhibidores de proteína quinasas.
CN101679386A (zh) 2007-04-13 2010-03-24 沃泰克斯药物股份有限公司 可用作激酶抑制剂的氨基嘧啶类化合物
MX2009011812A (es) 2007-05-02 2010-01-14 Vertex Pharma Aminopirimidinas utiles como inhibidores de cinasa.
MX2009011811A (es) * 2007-05-02 2010-01-14 Vertex Pharma Aminopirimidinas utiles como inhibidores de cinasa.
MX2009011810A (es) * 2007-05-02 2010-01-14 Vertex Pharma Tiazoles y pirazoles utiles como inhibidores de cinasa.
CN101687852A (zh) * 2007-05-24 2010-03-31 沃泰克斯药物股份有限公司 可用作激酶抑制剂的噻唑类和吡唑类化合物
CA2694499A1 (en) 2007-07-31 2009-02-05 Vertex Pharmaceuticals Incorporated Process for preparing 5-fluoro-1h-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof
JP2012501971A (ja) * 2008-09-03 2012-01-26 バーテックス ファーマシューティカルズ インコーポレイテッド 共結晶および共結晶を含む薬学的処方物
DE102009004245A1 (de) 2009-01-09 2010-07-15 Bayer Schering Pharma Aktiengesellschaft Neue anellierte, Heteroatom-verbrückte Pyrazol- und Imidazol-Derivate und ihre Verwendung
SMT201800202T1 (it) 2012-07-24 2018-05-02 Bial Portela & Ca Sa Composti di urea e loro uso come inibitori enzimatici
BR112015001769A2 (pt) * 2012-07-27 2017-08-22 Bial Portela & Ca Sa Processo para a síntese de compostos de ureia substituída
CA2918993C (en) 2013-07-24 2021-08-24 Bial - Portela & Ca, S.A. Imidazolecarboxamides and their use as faah inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133081A (en) * 1964-05-12 J-aminoindazole derivatives
CH397698A (de) * 1961-09-08 1965-08-31 Siegfried Ag Verfahren zur Herstellung neuer 1-Carbamyl-indazole
US3274203A (en) * 1963-05-31 1966-09-20 Du Pont 1-carbamyl and thiocarbamyl-3-amino-4-nonsubstituted and substituted pyrazoles
NL6707299A (show.php) * 1966-07-16 1968-01-17
DE1770649A1 (de) * 1968-06-15 1971-11-11 Bayer Ag Substituierte 3-Amino-indazole

Also Published As

Publication number Publication date
IL48642A (en) 1979-12-30
SE7513990L (sv) 1976-06-14
JPS5182266A (en) 1976-07-19
CA1059523A (en) 1979-07-31
YU315275A (en) 1982-02-28
AT343653B (de) 1978-06-12
NL7514521A (nl) 1976-06-15
SU604487A3 (ru) 1978-04-25
HU173557B (hu) 1979-06-28
LU73993A1 (show.php) 1976-11-11
SE419645B (sv) 1981-08-17
KE3078A (en) 1980-10-03
DD125484A5 (show.php) 1977-04-20
NO145382C (no) 1982-03-10
CH622250A5 (show.php) 1981-03-31
ES443429A1 (es) 1977-04-16
FR2293928A1 (fr) 1976-07-09
DE2458965A1 (de) 1976-06-16
IE42208L (en) 1976-06-13
DE2458965C3 (de) 1979-10-11
DK137082C (da) 1978-06-19
FR2293928B1 (show.php) 1979-09-21
IL48642A0 (en) 1976-02-29
ZA757777B (en) 1976-11-24
NO754024L (show.php) 1976-06-15
HK52580A (en) 1980-09-26
GB1490306A (en) 1977-11-02
AU8717075A (en) 1977-06-09
CS189731B2 (en) 1979-04-30
DK137082B (da) 1978-01-16
BE836528A (fr) 1976-06-11
PL99858B1 (pl) 1978-08-31
DE2458965B2 (de) 1979-02-22
FI753493A7 (show.php) 1976-06-14
US4051252A (en) 1977-09-27
NO145382B (no) 1981-11-30
ATA939775A (de) 1977-10-15
DK567275A (da) 1976-06-14

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