DE68906200T2 - Kondensierte pyrazol-3-oxo-propannitril-derivate und verfahren zu deren herstellung. - Google Patents

Kondensierte pyrazol-3-oxo-propannitril-derivate und verfahren zu deren herstellung.

Info

Publication number
DE68906200T2
DE68906200T2 DE8989110986T DE68906200T DE68906200T2 DE 68906200 T2 DE68906200 T2 DE 68906200T2 DE 8989110986 T DE8989110986 T DE 8989110986T DE 68906200 T DE68906200 T DE 68906200T DE 68906200 T2 DE68906200 T2 DE 68906200T2
Authority
DE
Germany
Prior art keywords
oxo
group
derivatives
propannitrile
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989110986T
Other languages
English (en)
Other versions
DE68906200D1 (de
Inventor
Gianfederico Doria
Anna Maria Isetta
Mario Ferrari
Domenico Trizio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE68906200D1 publication Critical patent/DE68906200D1/de
Publication of DE68906200T2 publication Critical patent/DE68906200T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8989110986T 1988-06-20 1989-06-16 Kondensierte pyrazol-3-oxo-propannitril-derivate und verfahren zu deren herstellung. Expired - Fee Related DE68906200T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888814587A GB8814587D0 (en) 1988-06-20 1988-06-20 Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation

Publications (2)

Publication Number Publication Date
DE68906200D1 DE68906200D1 (de) 1993-06-03
DE68906200T2 true DE68906200T2 (de) 1993-08-05

Family

ID=10638992

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989110986T Expired - Fee Related DE68906200T2 (de) 1988-06-20 1989-06-16 Kondensierte pyrazol-3-oxo-propannitril-derivate und verfahren zu deren herstellung.

Country Status (21)

Country Link
US (1) US5424308A (de)
EP (2) EP0422051A1 (de)
JP (1) JPH03505205A (de)
KR (1) KR900701756A (de)
CN (1) CN1022322C (de)
AT (1) ATE88700T1 (de)
AU (1) AU634966B2 (de)
CZ (1) CZ284336B6 (de)
DE (1) DE68906200T2 (de)
DK (1) DK163581C (de)
ES (1) ES2054930T3 (de)
GB (1) GB8814587D0 (de)
HU (1) HU206872B (de)
IE (1) IE63189B1 (de)
IL (1) IL90552A (de)
NZ (1) NZ229450A (de)
PT (1) PT90905B (de)
RU (1) RU2109735C1 (de)
WO (1) WO1989012630A1 (de)
YU (1) YU46937B (de)
ZA (1) ZA894678B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260328A (en) * 1989-04-06 1993-11-09 Farmitalia Carlo Erba Srl Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis
GB8907799D0 (en) * 1989-04-06 1989-05-17 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases
GB8916290D0 (en) * 1989-07-17 1989-08-31 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis
US5466823A (en) 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
US6716991B1 (en) 1993-11-30 2004-04-06 G. D. Searle & Co. Process for preparing a substituted pyrazolyl benzenesulfonamide for the treatment of inflammation
US6492411B1 (en) 1993-11-30 2002-12-10 G. D. Searle & Co. Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
CA2276945C (en) * 1993-11-30 2006-08-01 G.D. Searle & Co. Tricyclic-substituted pyrazolyl benzenesulfonamides and pharmaceutical compositions thereof
US5547975A (en) * 1994-09-20 1996-08-20 Talley; John J. Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5886016A (en) * 1995-09-15 1999-03-23 G.D. Searle & Co. Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5756529A (en) * 1995-09-29 1998-05-26 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies
GB9716103D0 (en) * 1997-07-30 1997-10-01 Pharmacia & Upjohn Spa Condensed heterocyclic compounds
US6849653B2 (en) 2001-09-19 2005-02-01 Pharmacia Corporation Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation
WO2003024935A2 (en) 2001-09-19 2003-03-27 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
CA2460939C (en) 2001-09-19 2008-07-29 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
CN114718407A (zh) * 2022-03-01 2022-07-08 东风柳州汽车有限公司 车窗控制方法、装置、设备及存储介质

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2989538A (en) * 1960-02-10 1961-06-20 Smith Kline French Lab Process for preparing pyrazoloindenone hydrazones
US3004983A (en) * 1960-05-16 1961-10-17 Smith Kline French Lab 4-aminopyrazolo [3, 4-a] indene derivatives
US4140785A (en) * 1978-05-08 1979-02-20 E. I. Du Pont De Nemours And Company N-(benzothienopyrazol)amide antirhinoviral agents
US4173634A (en) * 1979-02-23 1979-11-06 E. R. Squibb & Sons, Inc. Basically-substituted tricyclic pyrazoles useful as antiinflammatory agents
US4431657A (en) * 1982-05-24 1984-02-14 Ayerst, Mckenna & Harrison Inc. Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives
US4420476A (en) * 1982-05-24 1983-12-13 Averst McKenna & Harrison, Inc. Benzofuro[3,2-c]pyrazol-3-amine derivatives
US4816467A (en) * 1987-01-09 1989-03-28 Farmitalia Carlo Erba S.R.L Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use
BR8806571A (pt) * 1987-04-09 1989-10-17 Du Pont Indazois substituidos inseticidas
GB8814586D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation
GB8916290D0 (en) * 1989-07-17 1989-08-31 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis

Also Published As

Publication number Publication date
IE63189B1 (en) 1995-03-22
DK163581B (da) 1992-03-16
IL90552A0 (en) 1990-01-18
EP0422051A1 (de) 1991-04-17
IL90552A (en) 1994-08-26
ES2054930T3 (es) 1994-08-16
DK163581C (da) 1992-08-10
EP0347773B1 (de) 1993-04-28
PT90905A (pt) 1989-12-29
US5424308A (en) 1995-06-13
HU894019D0 (en) 1991-06-28
DK300890A (da) 1991-02-20
DK300890D0 (da) 1990-12-19
AU3769289A (en) 1990-01-12
CZ284336B6 (cs) 1998-10-14
HUT56076A (en) 1991-07-29
HU206872B (en) 1993-01-28
JPH03505205A (ja) 1991-11-14
WO1989012630A1 (en) 1989-12-28
CZ370189A3 (cs) 1998-07-15
KR900701756A (ko) 1990-12-04
CN1038642A (zh) 1990-01-10
YU125489A (en) 1991-04-30
RU2109735C1 (ru) 1998-04-27
DE68906200D1 (de) 1993-06-03
ATE88700T1 (de) 1993-05-15
EP0347773A1 (de) 1989-12-27
NZ229450A (en) 1990-08-28
ZA894678B (en) 1991-02-27
GB8814587D0 (en) 1988-07-27
AU634966B2 (en) 1993-03-11
CN1022322C (zh) 1993-10-06
YU46937B (sh) 1994-06-24
PT90905B (pt) 1994-12-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee