ID24730A - Senyawa-senyawa heterosiklik untuk penghambatan sekresi asam lambung, proses pembuatan dan komposisi-komposisi farmasinya - Google Patents

Senyawa-senyawa heterosiklik untuk penghambatan sekresi asam lambung, proses pembuatan dan komposisi-komposisi farmasinya

Info

Publication number
ID24730A
ID24730A IDW20000987A ID20000987A ID24730A ID 24730 A ID24730 A ID 24730A ID W20000987 A IDW20000987 A ID W20000987A ID 20000987 A ID20000987 A ID 20000987A ID 24730 A ID24730 A ID 24730A
Authority
ID
Indonesia
Prior art keywords
heterosiclic
balic
observation
compounds
manufacture process
Prior art date
Application number
IDW20000987A
Other languages
English (en)
Indonesian (id)
Inventor
Kosrat Amin
Mikael Dahlstrom
Peter Nordberg
Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ID24730A publication Critical patent/ID24730A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20000987A 1997-11-28 1998-11-18 Senyawa-senyawa heterosiklik untuk penghambatan sekresi asam lambung, proses pembuatan dan komposisi-komposisi farmasinya ID24730A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds

Publications (1)

Publication Number Publication Date
ID24730A true ID24730A (id) 2000-08-03

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000987A ID24730A (id) 1997-11-28 1998-11-18 Senyawa-senyawa heterosiklik untuk penghambatan sekresi asam lambung, proses pembuatan dan komposisi-komposisi farmasinya

Country Status (33)

Country Link
US (1) US6518270B1 (fr)
EP (1) EP1042324B1 (fr)
JP (1) JP2001525322A (fr)
KR (1) KR20010032559A (fr)
CN (1) CN1142933C (fr)
AR (1) AR016972A1 (fr)
AT (1) ATE233263T1 (fr)
AU (1) AU752187C (fr)
BR (1) BR9814755A (fr)
CA (1) CA2311798A1 (fr)
CZ (1) CZ292349B6 (fr)
DE (1) DE69811735T2 (fr)
DK (1) DK1042324T3 (fr)
EE (1) EE04060B1 (fr)
ES (1) ES2191356T3 (fr)
HK (1) HK1030216A1 (fr)
HU (1) HUP0100601A3 (fr)
ID (1) ID24730A (fr)
IL (1) IL136145A0 (fr)
IS (1) IS5486A (fr)
MY (1) MY121032A (fr)
NO (1) NO315704B1 (fr)
NZ (1) NZ504355A (fr)
PL (1) PL340920A1 (fr)
PT (1) PT1042324E (fr)
RU (1) RU2241000C2 (fr)
SE (1) SE9704404D0 (fr)
SK (1) SK283904B6 (fr)
TR (1) TR200001530T2 (fr)
TW (1) TW515798B (fr)
UA (1) UA70932C2 (fr)
WO (1) WO1999028322A1 (fr)
ZA (1) ZA9810468B (fr)

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WO2004022562A1 (fr) 2002-09-09 2004-03-18 Cellular Genomics, Inc. 6-arykl-imidazo[1,2-a]pyrazin-8-ylamines, procede de preparation et procede d'utilisation correspondants
AU2003266621A1 (en) * 2002-09-25 2004-04-19 Sankyo Company, Limited Medicinal composition for treatment for or prevention of visceral pain
WO2004029058A1 (fr) * 2002-09-25 2004-04-08 Sankyo Company, Limited Composition medicinale permettant d'inhiber une augmentation de la concentration sanguine de la gastrine
US7790709B2 (en) 2002-12-06 2010-09-07 Affinium Pharmaceuticals, Inc. Heterocyclic compounds, methods of making them and their use in therapy
WO2004072080A1 (fr) 2003-02-10 2004-08-26 Cellular Genomics, Inc. 8-heteroaryle-6-phenyle-imidazo[1,2-a]pyrazines comme modulateurs de l'activite du complexe hsp90
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
WO2004082586A2 (fr) * 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Compositions comportant plusieurs agents antibiotiques, et leurs procedes de mise en oeuvre
WO2005014599A1 (fr) 2003-06-04 2005-02-17 Cellular Genomics, Inc. Imidazo[1,2-a]pyrazin-8-ylamines et methodes d'inhibition de la tyrosine kinase de bruton par de tels composes
US7393848B2 (en) 2003-06-30 2008-07-01 Cgi Pharmaceuticals, Inc. Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds
US7259164B2 (en) 2003-08-11 2007-08-21 Cgi Pharmaceuticals, Inc. Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity
WO2005041961A1 (fr) 2003-11-03 2005-05-12 Astrazeneca Ab Procede d'utilisation
PT1828167E (pt) * 2004-06-04 2014-10-08 Debiopharm Int Sa Derivados de acrilamida como agentes antibióticos
US20070293532A1 (en) * 2004-07-28 2007-12-20 Takeda Pharmaceutical Compan6Y Limited Pyrrolo [2,3-C] Pyridine Compound, Process for Producing the Same, and Use
AU2005268767A1 (en) * 2004-08-02 2006-02-09 Altana Pharma Ag 5-substituted 1H-pyrrolo[3,2-B]pyridines
KR100946220B1 (ko) * 2004-09-03 2010-03-08 주식회사유한양행 피롤로[3,2-ｃ]피리딘 유도체 및 그의 제조방법
KR100958828B1 (ko) * 2004-09-03 2010-05-24 주식회사유한양행 피롤로[3,2-ｂ]피리딘 유도체 및 그의 제조방법
RU2378275C2 (ru) * 2004-09-03 2010-01-10 Юхан Корпорейшн ПРОИЗВОДНЫЕ ПИРРОЛО[3,2-c]ПИРИДИНА И СПОСОБ ИХ ПОЛУЧЕНИЯ
ATE533765T1 (de) 2004-09-03 2011-12-15 Yuhan Corp Pyrroloä2,3-cüpyridinderivate und verfahren für deren herstellung
WO2007024294A2 (fr) 2005-05-03 2007-03-01 Cgi Pharmaceuticals, Inc. Certains urees substitues, modulateurs de l'activite des kinases
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
WO2007067416A2 (fr) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Agents therapeutiques et ses procédés de fabrication et d'utilisation
TW200808802A (en) * 2006-06-06 2008-02-16 Schering Corp Imidazopyrazines as protein kinase inhibitors
EP2687533B1 (fr) 2006-07-20 2017-07-19 Debiopharm International SA Dérivés d'acrylamide en tant qu'inhibiteurs de FAB I
EP2125802A4 (fr) 2007-02-16 2014-08-20 Debiopharm Int Sa Sels, promédicaments et polymorphes d'inhibiteurs de fab 1
NZ587039A (en) 2008-02-13 2013-01-25 Gilead Connecticut Inc 6-aryl-imidazo[1, 2-a]pyrazine derivatives, method of making, and method of use thereof
AU2009325133B2 (en) 2008-12-08 2016-02-04 Gilead Connecticut, Inc. Imidazopyrazine Syk inhibitors
EP3123864A1 (fr) 2008-12-08 2017-02-01 Gilead Connecticut, Inc. Inhibiteurs de syk d'imidazopyrazine
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
AU2011226689B2 (en) 2010-03-11 2016-09-01 Kronos Bio, Inc. Imidazopyridines Syk inhibitors
RS58898B1 (sr) 2012-06-19 2019-08-30 Debiopharm Int Sa Prolek derivati (e)-n-metil-n-((3-metilbenzofuran-2-il)metil)-3-(7-okso-5,6,7,8-tetrahidro-1,8-naftiridin-3-il)akrilamida
KR101810798B1 (ko) 2013-07-30 2017-12-19 질레드 코네티컷 인코포레이티드 Ｓｙｋ 억제제의 다형체
UA115815C2 (uk) 2013-07-30 2017-12-26 Гіліад Коннектікут, Інк. Склад на основі інгібіторів syk
MX2016007311A (es) 2013-12-04 2016-09-07 Gilead Sciences Inc Metodos para tratar canceres.
GB201321738D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
TWI662037B (zh) 2013-12-23 2019-06-11 美商基利科學股份有限公司 脾酪胺酸激酶抑制劑
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
NZ726365A (en) 2014-07-14 2018-06-29 Gilead Sciences Inc Combinations for treating cancers
LT3419628T (lt) 2016-02-26 2021-01-25 Debiopharm International Sa Medikamentas diabetinėms pėdų infekcijoms gydyti
AU2018321264A1 (en) 2017-08-25 2020-02-27 Kronos Bio, Inc. Polymorphs of Syk inhibitors
CA3130848A1 (fr) 2019-02-22 2020-08-27 Kronos Bio, Inc. Formes solides de pyrazines condensees en tant qu'inhibiteur de syk

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US4507294A (en) * 1982-03-08 1985-03-26 Schering Corp. Imidazo[1,2-a]pyrazines
EP0068378B1 (fr) * 1981-06-26 1986-03-05 Schering Corporation Imidazo(1,2-a)pyridines et pyrazines, procédés pour leur préparation et composés pharmaceutiques les contenant
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
IL97931A0 (en) 1990-04-27 1992-06-21 Byk Gulden Lomberg Chem Fab Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5041442A (en) * 1990-07-31 1991-08-20 Syntex (U.S.A.) Inc. Pyrrolo(1,2-a)pyrazines as inhibitors of gastric acid secretion
AU8712191A (en) 1990-10-15 1992-05-20 Byk Gulden Lomberg Chemische Fabrik Gmbh New diazines
WO1993008190A1 (fr) * 1991-10-25 1993-04-29 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyrrolo-pyridazine a effets protecteurs du tube gastro-intestinal
WO1995019980A1 (fr) * 1994-01-19 1995-07-27 Sankyo Company, Limited Derive de pyrrolopyridazine
SE9602286D0 (sv) 1996-06-10 1996-06-10 Astra Ab New compounds
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds

Also Published As

Publication number Publication date
SK6742000A3 (en) 2001-03-12
AU752187B2 (en) 2002-09-12
AR016972A1 (es) 2001-08-01
MY121032A (en) 2005-12-30
SE9704404D0 (sv) 1997-11-28
JP2001525322A (ja) 2001-12-11
CZ292349B6 (cs) 2003-09-17
NO20002721L (no) 2000-07-28
US6518270B1 (en) 2003-02-11
TW515798B (en) 2003-01-01
CA2311798A1 (fr) 1999-06-10
ATE233263T1 (de) 2003-03-15
HUP0100601A3 (en) 2002-10-28
CN1142933C (zh) 2004-03-24
HK1030216A1 (en) 2001-04-27
NO315704B1 (no) 2003-10-13
AU1356599A (en) 1999-06-16
CZ20001947A3 (cs) 2000-11-15
EE200000315A (et) 2001-10-15
IL136145A0 (en) 2001-05-20
EP1042324A1 (fr) 2000-10-11
DE69811735T2 (de) 2003-12-18
WO1999028322A1 (fr) 1999-06-10
PL340920A1 (en) 2001-03-12
EP1042324B1 (fr) 2003-02-26
KR20010032559A (ko) 2001-04-25
RU2241000C2 (ru) 2004-11-27
ES2191356T3 (es) 2003-09-01
EE04060B1 (et) 2003-06-16
TR200001530T2 (tr) 2000-11-21
DE69811735D1 (de) 2003-04-03
DK1042324T3 (da) 2003-05-05
SK283904B6 (sk) 2004-04-06
NO20002721D0 (no) 2000-05-26
IS5486A (is) 2000-05-10
PT1042324E (pt) 2003-06-30
AU752187C (en) 2003-09-18
HUP0100601A2 (hu) 2001-09-28
NZ504355A (en) 2001-12-21
BR9814755A (pt) 2000-10-03
ZA9810468B (en) 1999-05-21
UA70932C2 (uk) 2004-11-15
CN1284078A (zh) 2001-02-14

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