HUT76637A - Bezoxazoles and pyridine derivatives, pharmaceutical compositions containing them, process for producing them and their use and the intermediates of the compounds - Google Patents
Bezoxazoles and pyridine derivatives, pharmaceutical compositions containing them, process for producing them and their use and the intermediates of the compounds Download PDFInfo
- Publication number
- HUT76637A HUT76637A HU9700264A HU9700264A HUT76637A HU T76637 A HUT76637 A HU T76637A HU 9700264 A HU9700264 A HU 9700264A HU 9700264 A HU9700264 A HU 9700264A HU T76637 A HUT76637 A HU T76637A
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutically acceptable
- formula
- compound
- benzoxazolyl
- acceptable salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
PCT/GB1995/001323 WO1996004261A1 (fr) | 1994-07-29 | 1995-06-07 | Benzoxoazoles et derives de pryridine destines a etre utilises pour le traitement du diabete tardif |
Publications (1)
Publication Number | Publication Date |
---|---|
HUT76637A true HUT76637A (en) | 1997-10-28 |
Family
ID=27267309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9700264A HUT76637A (en) | 1994-07-29 | 1995-07-28 | Bezoxazoles and pyridine derivatives, pharmaceutical compositions containing them, process for producing them and their use and the intermediates of the compounds |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0772605A1 (fr) |
AP (1) | AP776A (fr) |
BR (1) | BR9508468A (fr) |
CA (1) | CA2196079A1 (fr) |
CZ (1) | CZ25497A3 (fr) |
DZ (1) | DZ1916A1 (fr) |
FI (1) | FI970357A (fr) |
HU (1) | HUT76637A (fr) |
IL (3) | IL114759A (fr) |
MA (1) | MA23632A1 (fr) |
MX (1) | MX9700763A (fr) |
NO (1) | NO307827B1 (fr) |
OA (1) | OA10470A (fr) |
PL (1) | PL318766A1 (fr) |
SK (1) | SK12297A3 (fr) |
WO (2) | WO1996004261A1 (fr) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
DK0916651T3 (da) * | 1996-04-04 | 2003-12-01 | Sankyo Co | Phenylalkylcarboxylsyrederivater |
US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
IL135177A0 (en) | 1997-10-02 | 2001-05-20 | Sankyo Co | Amidocarboxylic acid derivatives and pharmaceutical compositions containing the same |
US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
MXPA00004036A (es) | 1997-10-27 | 2006-05-24 | Reddys Lab Ltd Dr | Compuestos triciclicos novedosos y su uso en medicina; proceso para su preparacion y composiciones farmaceuticas que los contienen.. |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
WO1999019313A1 (fr) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Nouveaux composes tricycliques et leur utilisation en medecine, procede de preparation de ces derniers et compositions pharmaceutiques les contenant |
CN1280574A (zh) * | 1997-10-27 | 2001-01-17 | 雷迪研究基金会 | 新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物 |
US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
US6265401B1 (en) | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
CA2307068C (fr) | 1997-10-27 | 2007-04-10 | Dr. Reddy's Research Foundation | Composes bicycliques, procede de preparation et compositions pharmaceutiques les contenant |
NZ504106A (en) * | 1998-05-27 | 2003-02-28 | Dr | Fused Oxazine, Thiazine and pipyridine compounds, process for their preparation and pharmaceutical compositions containing them |
EP1113801A4 (fr) | 1998-09-17 | 2002-10-02 | Bristol Myers Squibb Co | PROCEDE POUR TRAITER L'ATHEROSCLEROSE AU MOYEN D'UN INHIBITEUR D'aP2 OU D'UNE COMBINAISON CORRESPONDANTE |
JP2002527516A (ja) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物、それらの製造及び使用 |
JP2002527501A (ja) | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物、その製造及び利用 |
AU6325799A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
EP1123279A1 (fr) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | Nouveaux composes, preparation et utilisation correspondantes |
US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
AU6325899A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
EP1123268A1 (fr) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | Nouveaux composes, leur preparation et leur utilisation |
US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
CN1323300A (zh) * | 1998-10-29 | 2001-11-21 | 雷迪研究基金会 | 制备新的抗糖尿病剂的改进方法 |
US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
WO2000063189A1 (fr) * | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Formes cristallines de r-guanidines, d'arginine ou de (l)-arginine (2s-2-ethoxy-3-{4-[2-(10h-phenoxazin-10-yl)ethoxy]phenyl}propanoate |
WO2000063209A1 (fr) * | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | Nouveaux composes, preparation et utilisation associees |
US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
KR20020005703A (ko) * | 1999-04-20 | 2002-01-17 | 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 | 신규한 화합물, 그의 제법 및 용도 |
EP1171431A1 (fr) * | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Composes, leur preparation et utilisation |
US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
KR100610578B1 (ko) | 1999-04-28 | 2006-08-09 | 닥터 레디스 레보러터리즈 리미티드 | 치환된 이원 헤테로고리, 비만증 및 고콜레스테롤증치료제로서의 그 용도 |
CA2382966A1 (fr) | 1999-08-27 | 2001-03-08 | Eli Lilly And Company | Derives de biaryl-oxa(thia)zole et leur utilisation en tant que modulateurs de ppar |
HU230609B1 (hu) * | 2000-01-19 | 2017-03-28 | Cadila Healthcare Ltd. | Hipolipidémiás és hipokoleszterinémiás hatású szubsztituált pirrolszármazékok, azokat tartalmazó gyógyszerkészítmények, eljárás előállításukra, köztitermékek és alkalmazásuk |
WO2001055086A1 (fr) * | 2000-01-28 | 2001-08-02 | Novo Nordisk A/S | Derives d'acide propionique a substitution alkynyle et leur utilisation pour lutter contre le diabete et l'obesite |
US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
WO2001087860A2 (fr) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Nouveaux benzoxazinones utilises comme modulateurs du recepteur gamma active de la proliferation des peroxysomes, et methode de traitement associee |
EP1280783A2 (fr) * | 2000-05-12 | 2003-02-05 | Ortho-McNeil Pharmaceutical, Inc. | Methodes de traitement mettant en oeuvre des benzoxazinones comme modulateurs du recepteur gamma active par le proliferateur du peroxisome |
PT1280784E (pt) * | 2000-05-12 | 2007-09-03 | Ortho Mcneil Pharm Inc | 4h-benzo [1,4] oxazin-3-onas biologicamente activas. |
US6987123B2 (en) * | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2005518408A (ja) | 2001-12-29 | 2005-06-23 | ノボ ノルディスク アクティーゼルスカブ | 異常脂肪血症を治療するための、glp−1化合物と他の薬物との組み合わせ使用 |
US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
EP2154131A4 (fr) * | 2007-04-26 | 2011-09-21 | Pharmafrontier Co Ltd | Inhibiteur du récepteur couplé à protéine g et produit pharmaceutique |
WO2012104869A1 (fr) | 2011-01-31 | 2012-08-09 | Cadila Healthcare Limited | Traitement de la lipodystrophie |
KR101617812B1 (ko) | 2013-04-22 | 2016-05-03 | 카딜라 핼쓰캐어 리미티드 | 비알콜성 지방간 질환을 위한 신규 조성물 |
US20160107989A1 (en) | 2013-05-30 | 2016-04-21 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
TW201513857A (zh) | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | 協同性組成物 |
IN2013MU02470A (fr) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
US10112898B2 (en) | 2013-09-06 | 2018-10-30 | Cadila Healthcare Limited | Process for the preparation of saroglitazar pharmaceutical salts |
WO2017064635A2 (fr) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Composé pyrrole, compositions et procédé de préparation associé |
JP6840853B2 (ja) | 2016-12-09 | 2021-03-10 | カディラ・ヘルスケア・リミテッド | 原発性胆汁性胆管炎の治療 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
SK695A3 (en) * | 1992-07-03 | 1995-07-11 | Smithkline Beecham Plc | Heterocyclic compounds method of their production and using |
-
1995
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/fr active Search and Examination
- 1995-06-07 BR BR9508468A patent/BR9508468A/pt unknown
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/fr active
- 1995-07-27 IL IL11475995A patent/IL114759A/xx unknown
- 1995-07-27 MA MA23972A patent/MA23632A1/fr unknown
- 1995-07-27 IL IL12552595A patent/IL125525A/xx unknown
- 1995-07-28 SK SK122-97A patent/SK12297A3/sk unknown
- 1995-07-28 PL PL95318766A patent/PL318766A1/xx unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 HU HU9700264A patent/HUT76637A/hu unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/fr not_active Application Discontinuation
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/cs unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/fr not_active Withdrawn
- 1995-07-28 CA CA002196079A patent/CA2196079A1/fr not_active Abandoned
- 1995-07-28 MX MX9700763A patent/MX9700763A/es unknown
-
1997
- 1997-01-28 FI FI970357A patent/FI970357A/fi unknown
- 1997-01-28 NO NO970373A patent/NO307827B1/no not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL125525A0 (en) | 1999-03-12 |
IL114759A (en) | 1999-10-28 |
WO1996004261A1 (fr) | 1996-02-15 |
MA23632A1 (fr) | 1996-04-01 |
NO970373L (no) | 1997-03-18 |
NO970373D0 (no) | 1997-01-28 |
WO1996004260A1 (fr) | 1996-02-15 |
EP0772605A1 (fr) | 1997-05-14 |
OA10470A (en) | 2002-04-08 |
IL114759A0 (en) | 1995-12-31 |
MX9700763A (es) | 1997-05-31 |
DZ1916A1 (fr) | 2002-02-17 |
SK12297A3 (en) | 1997-08-06 |
CA2196079A1 (fr) | 1996-02-15 |
CZ25497A3 (en) | 1997-09-17 |
NO307827B1 (no) | 2000-06-05 |
IL125525A (en) | 2000-02-29 |
FI970357A0 (fi) | 1997-01-28 |
FI970357A (fi) | 1997-03-26 |
AP9700918A0 (en) | 1997-01-31 |
AP776A (en) | 1999-10-28 |
PL318766A1 (en) | 1997-07-07 |
BR9508468A (pt) | 1997-11-25 |
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