AP776A - Benzoxazoles and pyridine derivatives useful in the treatment of the type Ii diabetes. - Google Patents

Benzoxazoles and pyridine derivatives useful in the treatment of the type Ii diabetes. Download PDF

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Publication number
AP776A
AP776A APAP/P/1997/000918A AP9700918A AP776A AP 776 A AP776 A AP 776A AP 9700918 A AP9700918 A AP 9700918A AP 776 A AP776 A AP 776A
Authority
AP
ARIPO
Prior art keywords
pharmaceutically acceptable
formula
compound
acceptable salt
treatment
Prior art date
Application number
APAP/P/1997/000918A
Other languages
English (en)
Other versions
AP9700918A0 (en
Inventor
David Haigh
Harshad Kantilal Rami
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415330A external-priority patent/GB9415330D0/en
Priority claimed from GBGB9425599.9A external-priority patent/GB9425599D0/en
Priority claimed from GBGB9509923.0A external-priority patent/GB9509923D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of AP9700918A0 publication Critical patent/AP9700918A0/xx
Application granted granted Critical
Publication of AP776A publication Critical patent/AP776A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
APAP/P/1997/000918A 1994-07-29 1995-07-28 Benzoxazoles and pyridine derivatives useful in the treatment of the type Ii diabetes. AP776A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9415330A GB9415330D0 (en) 1994-07-29 1994-07-29 Novel compounds
GBGB9425599.9A GB9425599D0 (en) 1994-12-19 1994-12-19 Novel compounds
GBGB9509923.0A GB9509923D0 (en) 1995-05-17 1995-05-17 Novel compounds
PCT/GB1995/001323 WO1996004261A1 (fr) 1994-07-29 1995-06-07 Benzoxoazoles et derives de pryridine destines a etre utilises pour le traitement du diabete tardif

Publications (2)

Publication Number Publication Date
AP9700918A0 AP9700918A0 (en) 1997-01-31
AP776A true AP776A (en) 1999-10-28

Family

ID=27267309

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/000918A AP776A (en) 1994-07-29 1995-07-28 Benzoxazoles and pyridine derivatives useful in the treatment of the type Ii diabetes.

Country Status (16)

Country Link
EP (1) EP0772605A1 (fr)
AP (1) AP776A (fr)
BR (1) BR9508468A (fr)
CA (1) CA2196079A1 (fr)
CZ (1) CZ25497A3 (fr)
DZ (1) DZ1916A1 (fr)
FI (1) FI970357L (fr)
HU (1) HUT76637A (fr)
IL (3) IL125525A (fr)
MA (1) MA23632A1 (fr)
MX (1) MX9700763A (fr)
NO (1) NO307827B1 (fr)
OA (1) OA10470A (fr)
PL (1) PL318766A1 (fr)
SK (1) SK12297A3 (fr)
WO (2) WO1996004261A1 (fr)

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US6468996B1 (en) 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
WO2000023416A1 (fr) * 1998-10-21 2000-04-27 Novo Nordisk A/S Nouveaux composes, leur preparation et leur utilisation
US6300339B1 (en) 1998-10-21 2001-10-09 Novo Nordisk A/S Compounds, their preparation and use
WO2000023445A1 (fr) * 1998-10-21 2000-04-27 Novo Nordisk A/S Nouveaux composes, leur preparation et leur utilisation
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US6365586B1 (en) 1998-10-21 2002-04-02 Novo Nordisk A/S Compounds, their preparation and use
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WO2000023425A1 (fr) * 1998-10-21 2000-04-27 Novo Nordisk A/S Nouveaux composes, preparation et utilisation correspondantes
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US6214820B1 (en) 1998-10-21 2001-04-10 Novo Nordisk A/S Compounds, their preparation and use
US6248781B1 (en) 1998-10-21 2001-06-19 Novo Nordisk A/S Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
UA60386C2 (uk) * 1998-10-29 2003-10-15 Reddys Laboratories Ltd Спосіб одержання похідних 3-[4-[2-(феноксазин-10-іл)метокси]феніл]пропіонової кислоти (варіанти) та проміжні сполуки для їх отримання
WO2000063189A1 (fr) * 1999-04-16 2000-10-26 Novo Nordisk A/S Formes cristallines de r-guanidines, d'arginine ou de (l)-arginine (2s-2-ethoxy-3-{4-[2-(10h-phenoxazin-10-yl)ethoxy]phenyl}propanoate
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EP1171431A1 (fr) * 1999-04-20 2002-01-16 Novo Nordisk A/S Composes, leur preparation et utilisation
JP2002542246A (ja) 1999-04-20 2002-12-10 ノボ ノルディスク アクティーゼルスカブ 新規な化合物、それらの製造及び使用
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EP1175412A1 (fr) 1999-04-28 2002-01-30 Dr. Reddy's Research Foundation Heterocycles bicycliques substitues, procede pour leur preparation et leur utilisation comme agents contre l'obesite et comme agents hypocholesterolemiques
WO2001016120A1 (fr) 1999-08-27 2001-03-08 Eli Lilly And Company Derives de biaryl-oxa(thia)zole et leur utilisation en tant que modulateurs de ppar
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EP2154131A4 (fr) * 2007-04-26 2011-09-21 Pharmafrontier Co Ltd Inhibiteur du récepteur couplé à protéine g et produit pharmaceutique
EP3009136A1 (fr) 2011-01-31 2016-04-20 Cadila Healthcare Limited Traitement de la lipodystrophie
UA114360C2 (uk) 2013-04-22 2017-05-25 Каділа Хелткере Лімітед Спосіб лікування та/або зменшення інтенсивності неалкогольної жирової хвороби печінки (нжхп)
US20160107989A1 (en) 2013-05-30 2016-04-21 Cadila Healthcare Limited A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
TW201513857A (zh) 2013-07-05 2015-04-16 Cadila Healthcare Ltd 協同性組成物
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Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1994001420A1 (fr) * 1992-07-03 1994-01-20 Smithkline Beecham Plc Composes heterocycliques comme produits pharmaceutiques

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Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1994001420A1 (fr) * 1992-07-03 1994-01-20 Smithkline Beecham Plc Composes heterocycliques comme produits pharmaceutiques

Also Published As

Publication number Publication date
FI970357A0 (fi) 1997-01-28
MA23632A1 (fr) 1996-04-01
CA2196079A1 (fr) 1996-02-15
OA10470A (en) 2002-04-08
NO970373D0 (no) 1997-01-28
HUT76637A (en) 1997-10-28
NO307827B1 (no) 2000-06-05
CZ25497A3 (en) 1997-09-17
SK12297A3 (en) 1997-08-06
PL318766A1 (en) 1997-07-07
AP9700918A0 (en) 1997-01-31
DZ1916A1 (fr) 2002-02-17
FI970357A7 (fi) 1997-03-26
IL114759A0 (en) 1995-12-31
IL114759A (en) 1999-10-28
WO1996004260A1 (fr) 1996-02-15
WO1996004261A1 (fr) 1996-02-15
NO970373L (no) 1997-03-18
EP0772605A1 (fr) 1997-05-14
MX9700763A (es) 1997-05-31
FI970357L (fi) 1997-03-26
BR9508468A (pt) 1997-11-25
IL125525A0 (en) 1999-03-12
IL125525A (en) 2000-02-29

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