PL357017A1 - Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity - Google Patents

Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity

Info

Publication number
PL357017A1
PL357017A1 PL01357017A PL35701701A PL357017A1 PL 357017 A1 PL357017 A1 PL 357017A1 PL 01357017 A PL01357017 A PL 01357017A PL 35701701 A PL35701701 A PL 35701701A PL 357017 A1 PL357017 A1 PL 357017A1
Authority
PL
Poland
Prior art keywords
alkynylsubstituted
obesity
propionic acid
acid derivatives
use against
Prior art date
Application number
PL01357017A
Other languages
Polish (pl)
Inventor
John Patrick Mogensen
Per Sauerberg
Paul Stanley Bury
Lone Jeppesen
Ingrid Pettersson
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of PL357017A1 publication Critical patent/PL357017A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
PL01357017A 2000-01-28 2001-01-26 Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity PL357017A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200000137 2000-01-28
DKPA200001065 2000-07-07
DKPA200001593 2000-10-25
PCT/DK2001/000057 WO2001055086A1 (en) 2000-01-28 2001-01-26 Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity

Publications (1)

Publication Number Publication Date
PL357017A1 true PL357017A1 (en) 2004-07-12

Family

ID=27222337

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01357017A PL357017A1 (en) 2000-01-28 2001-01-26 Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity

Country Status (13)

Country Link
EP (1) EP1254102A1 (en)
JP (1) JP2003520839A (en)
KR (1) KR20020090211A (en)
CN (1) CN1396904A (en)
AU (1) AU2831801A (en)
BR (1) BR0107902A (en)
CA (1) CA2396372A1 (en)
HU (1) HUP0204247A3 (en)
IL (1) IL150259A0 (en)
MX (1) MXPA02007295A (en)
NO (1) NO20023567L (en)
PL (1) PL357017A1 (en)
WO (1) WO2001055086A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI311133B (en) 2001-04-20 2009-06-21 Eisai R&D Man Co Ltd Carboxylic acid derivativeand the salt thereof
EP1452521A4 (en) 2001-08-17 2007-03-14 Eisai R&D Man Co Ltd Cyclic compound and ppar agonist
RU2004114875A (en) * 2001-10-17 2005-09-10 Ново Нордиск А/С (DK) DICARBOXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND THERAPEUTIC USE
US7220877B2 (en) 2001-10-17 2007-05-22 Novo Nordisk A/S Compounds, their preparation and use
ITRM20020014A1 (en) * 2002-01-15 2003-07-15 Sigma Tau Ind Farmaceuti DERIVATIVES OF A-PHENYLTHIOCARBOXYL AND A-PHYLYOXYCARBOXYL ACIDS USEFUL FOR THE TREATMENT OF DISEASES THAT RESPOND TO THE ACTIVATION OF
WO2004022533A1 (en) * 2002-09-05 2004-03-18 Novo Nordisk A/S Novel vinyl carboxylic acid derivatives and their therapeutical use
JP4981662B2 (en) 2004-05-05 2012-07-25 ハイ・ポイント・ファーマスーティカルズ、エルエルシー New compounds, their preparation and use
JP2008504249A (en) * 2004-06-28 2008-02-14 ノボ　ノルディスク　アクティーゼルスカブ Methods for treating diabetes
EA201101085A1 (en) 2005-12-22 2012-05-30 ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи PHENOXYACIC ACIDS AS PPAR DELTA ACTIVATORS
US10307480B2 (en) 2014-11-06 2019-06-04 Scholar Rock, Inc. Anti-pro/latent-myostatin antibodies and uses thereof
CA3036652A1 (en) 2015-09-15 2017-03-23 Scholar Rock, Inc. Anti-pro/latent-myostatin antibodies and uses thereof
DK3565592T3 (en) * 2017-01-06 2023-05-01 Scholar Rock Inc TREATMENT OF METABOLIC DISEASES BY INHIBITION OF MYSTATIN ACTIVATION
CA3185909A1 (en) 2020-07-22 2022-01-27 Reneo Pharmaceuticals, Inc. Crystalline ppar-delta agonist
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK695A3 (en) * 1992-07-03 1995-07-11 Smithkline Beecham Plc Heterocyclic compounds method of their production and using
FR2707989B1 (en) * 1993-07-22 1995-10-13 Pf Medicament New silylated benzylamine derivatives, their salts, their manufacturing processes and the pharmaceutical compositions containing them.
WO1996004261A1 (en) * 1994-07-29 1996-02-15 Smithkline Beecham Plc Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes
GB9600464D0 (en) * 1996-01-09 1996-03-13 Smithkline Beecham Plc Novel method
GB9606805D0 (en) * 1996-03-30 1996-06-05 Glaxo Wellcome Inc Medicaments

Also Published As

Publication number Publication date
MXPA02007295A (en) 2002-11-29
HUP0204247A2 (en) 2003-04-28
BR0107902A (en) 2002-11-05
KR20020090211A (en) 2002-11-30
EP1254102A1 (en) 2002-11-06
NO20023567D0 (en) 2002-07-26
NO20023567L (en) 2002-09-25
AU2831801A (en) 2001-08-07
JP2003520839A (en) 2003-07-08
CN1396904A (en) 2003-02-12
CA2396372A1 (en) 2001-08-02
WO2001055086A1 (en) 2001-08-02
IL150259A0 (en) 2002-12-01
HUP0204247A3 (en) 2003-10-28

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)