AU2001282268A1 - Phenantridine derivatives and their use as anti-telomerase agent - Google Patents

Phenantridine derivatives and their use as anti-telomerase agent

Info

Publication number
AU2001282268A1
AU2001282268A1 AU2001282268A AU8226801A AU2001282268A1 AU 2001282268 A1 AU2001282268 A1 AU 2001282268A1 AU 2001282268 A AU2001282268 A AU 2001282268A AU 8226801 A AU8226801 A AU 8226801A AU 2001282268 A1 AU2001282268 A1 AU 2001282268A1
Authority
AU
Australia
Prior art keywords
phenantridine
derivatives
telomerase agent
telomerase
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001282268A
Inventor
Abdelazize Laoui
Patrick Mailliet
Jean-Louis Mergny
Jean-Francois Riou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of AU2001282268A1 publication Critical patent/AU2001282268A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines
AU2001282268A 2000-08-08 2001-08-07 Phenantridine derivatives and their use as anti-telomerase agent Abandoned AU2001282268A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0010422 2000-08-08
FR0010422 2000-08-08
PCT/FR2001/002560 WO2002012194A1 (en) 2000-08-08 2001-08-07 Phenantridine derivatives and their use as anti-telomerase agent

Publications (1)

Publication Number Publication Date
AU2001282268A1 true AU2001282268A1 (en) 2002-02-18

Family

ID=8853389

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001282268A Abandoned AU2001282268A1 (en) 2000-08-08 2001-08-07 Phenantridine derivatives and their use as anti-telomerase agent

Country Status (3)

Country Link
US (1) US20020103169A1 (en)
AU (1) AU2001282268A1 (en)
WO (1) WO2002012194A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8293716B2 (en) 2005-05-26 2012-10-23 Ramot At Tel Aviv University Ltd. Method of treating cancer by modulation of mortalin
EP2061464A2 (en) * 2006-09-14 2009-05-27 Ramot, at Tel Aviv University Ltd. Combination therapy for tumoral disease treatment
US8470793B2 (en) 2007-09-25 2013-06-25 Ramot At Tel-Aviv University Ltd. Down-regulation of mortalin by siRNA

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB816236A (en) * 1956-06-27 1959-07-08 Boots Pure Drug Co Ltd Improvements in the preparation of phenanthridine compounds
ATE244241T1 (en) * 1998-02-04 2003-07-15 Univ Texas INHIBITION OF HUMAN TELOMERASE BY G-QUADRUPLEX INTERACTION COMPOUND
PL355667A1 (en) * 1999-11-29 2004-05-04 Aventis Pharma S.A. Arylamine derivatives and their use as anti-telomerase agent

Also Published As

Publication number Publication date
US20020103169A1 (en) 2002-08-01
WO2002012194A1 (en) 2002-02-14

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