AU2001288972A1 - Antipsychotic sulfonamide-heterocycles, and methods of use thereof - Google Patents

Antipsychotic sulfonamide-heterocycles, and methods of use thereof

Info

Publication number
AU2001288972A1
AU2001288972A1 AU2001288972A AU8897201A AU2001288972A1 AU 2001288972 A1 AU2001288972 A1 AU 2001288972A1 AU 2001288972 A AU2001288972 A AU 2001288972A AU 8897201 A AU8897201 A AU 8897201A AU 2001288972 A1 AU2001288972 A1 AU 2001288972A1
Authority
AU
Australia
Prior art keywords
antipsychotic
heterocycles
sulfonamide
methods
antipsychotic sulfonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001288972A
Inventor
Brian M. Aquila
Gregory D. Cuny
James R Hauske
Heike Radeke
Liming Shao
Xinhe Wu
Roger L. Xie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunovion Pharmaceuticals Inc
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of AU2001288972A1 publication Critical patent/AU2001288972A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
AU2001288972A 2000-09-11 2001-09-10 Antipsychotic sulfonamide-heterocycles, and methods of use thereof Abandoned AU2001288972A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23160700P 2000-09-11 2000-09-11
US60/231,607 2000-09-11
PCT/US2001/028267 WO2002022579A2 (en) 2000-09-11 2001-09-10 Antipsychotic sulfonamide-heterocycles, and methods of use thereof

Publications (1)

Publication Number Publication Date
AU2001288972A1 true AU2001288972A1 (en) 2002-03-26

Family

ID=22869943

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001288972A Abandoned AU2001288972A1 (en) 2000-09-11 2001-09-10 Antipsychotic sulfonamide-heterocycles, and methods of use thereof

Country Status (3)

Country Link
US (2) US6703383B2 (en)
AU (1) AU2001288972A1 (en)
WO (1) WO2002022579A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7294637B2 (en) * 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
AU2001290873B2 (en) * 2000-09-11 2006-07-27 Sepracor Inc. Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission)
US7153858B2 (en) * 2003-01-31 2006-12-26 Epix Delaware, Inc. Arylpiperazinyl compounds
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536667A (en) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド 5HT receptor-mediated neurogenesis
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
US8748419B2 (en) * 2006-06-16 2014-06-10 Theracos, Inc. Treating obesity with muscarinic receptor M1 antagonists
CN101472476B (en) * 2006-06-16 2013-10-30 泰拉科斯有限公司 Treating obesity with muscarinic receptor M1 antagonists
US7998971B2 (en) 2006-09-08 2011-08-16 Braincells Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
MA33358B1 (en) 2009-05-15 2012-06-01 Novartis Ag Arylperidine as aldosterone synthase inhibitors
SG177740A1 (en) * 2009-07-23 2012-02-28 Univ Vanderbilt Substituted benzoimidazolesulfonamides and substituted indolesulfonamides as mglur4 potentiators
PL395470A1 (en) 2011-06-29 2013-01-07 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Alicyclic amines sulfonamide derivatives for the treatment of diseases of the central nervous system

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3534049A (en) * 1968-04-12 1970-10-13 American Home Prod 1 - substituted - 3 - (1 - hydroxy - n - (arylsulfonyl)formimidoyl)pyridines and derivatives
DE2347390A1 (en) * 1973-09-17 1975-04-03 Schering Ag Pyrido-/1,4/-oxazepines and -diazepines - prepd. by reacting 2-(amino- or hydroxy-methyl)-piperidines with carbonyl cpds.
US3933829A (en) * 1974-08-22 1976-01-20 John Wyeth & Brother Limited 4-Aminoquinoline derivatives
DE2718405A1 (en) 1977-04-26 1978-11-02 Boehringer Sohn Ingelheim NEW N-NECK CLAMP ON 1- (3-BENZOYLPROPYL) -4-PIPERIDYL NECK CLAMP ON -SULPHONIC ACID AMIDES AND METHOD FOR THE PRODUCTION THEREOF
US5994392A (en) 1988-02-26 1999-11-30 Neuromedica, Inc. Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid
DE4032766A1 (en) 1990-10-16 1992-04-30 Basf Ag PHENYLPIPERIDINOYLAMINE AND MEDICINAL PRODUCTS CONTAINING THEM
GB9202238D0 (en) 1992-02-03 1992-03-18 Wellcome Found Compounds
US5721255A (en) 1992-08-19 1998-02-24 Pfizer Inc. Substituted benzylamino nitrogen containing non-aromatic heterocycles
WO1995007908A1 (en) 1993-09-17 1995-03-23 Pfizer Inc. Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds
HU217837B (en) 1994-05-18 2000-04-28 EGIS Gyógyszergyár Rt. Acid-amide derivatives, pharmaceutical compositions containing them and process for producing them
US6194581B1 (en) 1995-04-07 2001-02-27 Merck & Co., Inc. Substituted pyridines useful as modulators of acetylcholine receptors
IL117798A (en) * 1995-04-07 2001-11-25 Schering Plough Corp Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases and pharmaceutical compositions comprising them
US5794887A (en) 1995-11-17 1998-08-18 Komerath; Narayanan M. Stagnation point vortex controller
WO1997040010A1 (en) 1996-04-24 1997-10-30 Emory University Halogenated naphthyl methoxy piperidines for mapping serotonin transporter sites
GB9702194D0 (en) 1997-02-04 1997-03-26 Lilly Co Eli Sulphonide derivatives
WO1998054168A1 (en) * 1997-05-30 1998-12-03 Banyu Pharmaceutical Co., Ltd. 2-oxoimidazole derivatives
US6004982A (en) * 1997-09-15 1999-12-21 Hoechst Marion Roussel, Inc. 4-piperidinyl) H-2-benzopyran derivatives useful as antipsychotic agents
US6407121B1 (en) 1998-03-19 2002-06-18 Nihon Nohyaku Co., Ltd. Arylpiperidine derivatives and use thereof
US6407103B2 (en) * 1998-04-21 2002-06-18 Bristol-Myers Squibb Pharma Company Indeno [1,2-c] pyrazol-4-ones and their uses
FR2805817B1 (en) 2000-03-03 2002-04-26 Aventis Pharma Sa PHARMACEUTICAL COMPOSITIONS CONTAINING AZETIDINE DERIVATIVES, NOVEL AZETIDINE DERIVATIVES AND THEIR PREPARATION
FR2805810B1 (en) 2000-03-03 2002-04-26 Aventis Pharma Sa PHARMACEUTICAL COMPOSITIONS CONTAINING 3- AMINO-AZETIDINE DERIVATIVES, THE NEW DERIVATIVES AND THEIR PREPARATION
EP2240966A2 (en) 2008-01-16 2010-10-20 Technion Research & Development Foundation Ltd. Spectrum manipulation device and method

Also Published As

Publication number Publication date
US6872716B2 (en) 2005-03-29
US6703383B2 (en) 2004-03-09
WO2002022579A3 (en) 2003-01-09
WO2002022579A2 (en) 2002-03-21
US20040235832A1 (en) 2004-11-25
US20020065265A1 (en) 2002-05-30

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