AU2002222001A1 - 3-arylindole derivatives and their use as CB2 receptor agonists - Google Patents

3-arylindole derivatives and their use as CB2 receptor agonists

Info

Publication number
AU2002222001A1
AU2002222001A1 AU2002222001A AU2200102A AU2002222001A1 AU 2002222001 A1 AU2002222001 A1 AU 2002222001A1 AU 2002222001 A AU2002222001 A AU 2002222001A AU 2200102 A AU2200102 A AU 2200102A AU 2002222001 A1 AU2002222001 A1 AU 2002222001A1
Authority
AU
Australia
Prior art keywords
receptor agonists
arylindole derivatives
arylindole
derivatives
agonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002222001A
Inventor
Francis Barth
Christian Congy
Carole Guillaumont
Murielle Rinaldi
Fabienne Vasse
Claude Vernhet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Publication of AU2002222001A1 publication Critical patent/AU2002222001A1/en
Assigned to SANOFI-AVENTIS reassignment SANOFI-AVENTIS Amend patent request/document other than specification (104) Assignors: SANOFI-SYNTHELABO
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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AU2002222001A 2000-11-22 2001-11-21 3-arylindole derivatives and their use as CB2 receptor agonists Abandoned AU2002222001A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0015158 2000-11-22
FR0015158A FR2816938B1 (en) 2000-11-22 2000-11-22 3-AROYLINDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
PCT/FR2001/003665 WO2002042269A1 (en) 2000-11-22 2001-11-21 3-arylindole derivatives and their use as cb2 receptor agonists

Publications (1)

Publication Number Publication Date
AU2002222001A1 true AU2002222001A1 (en) 2002-06-03

Family

ID=8856819

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002222001A Abandoned AU2002222001A1 (en) 2000-11-22 2001-11-21 3-arylindole derivatives and their use as CB2 receptor agonists

Country Status (32)

Country Link
US (1) US6995184B2 (en)
EP (1) EP1339679B1 (en)
JP (1) JP4264258B2 (en)
KR (1) KR20030048161A (en)
CN (1) CN1234688C (en)
AR (1) AR033594A1 (en)
AT (1) ATE301638T1 (en)
AU (1) AU2002222001A1 (en)
BG (1) BG107827A (en)
BR (1) BR0115580A (en)
CA (1) CA2427444A1 (en)
CZ (1) CZ20031392A3 (en)
DE (1) DE60112607T2 (en)
DK (1) DK1339679T3 (en)
DZ (1) DZ3443A1 (en)
EA (1) EA005854B1 (en)
EE (1) EE200300244A (en)
ES (1) ES2247201T3 (en)
FR (1) FR2816938B1 (en)
HR (1) HRP20030417A2 (en)
HU (1) HUP0400561A2 (en)
IL (1) IL155634A0 (en)
IS (1) IS6802A (en)
MA (1) MA26959A1 (en)
MX (1) MXPA03004549A (en)
NO (1) NO20031952L (en)
NZ (1) NZ525609A (en)
PL (1) PL362276A1 (en)
SK (1) SK6042003A3 (en)
TW (1) TWI224592B (en)
WO (1) WO2002042269A1 (en)
ZA (1) ZA200303728B (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200407110A (en) * 2001-11-23 2004-05-16 Astrazeneca Ab New use for the treatment of gastroesophageal reflux disease
JP2006517194A (en) 2002-06-06 2006-07-20 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム Methods, compositions and articles for regulating bone growth
ATE375349T1 (en) 2002-08-02 2007-10-15 Merck & Co Inc SUBSTITUTED FURO(2,3-B)PYRIDINE DERIVATIVES
FR2843964B1 (en) * 2002-08-29 2004-10-01 Sanofi Synthelabo DIOXANE-2-ALKYLCARBAMATES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2847899B1 (en) 2002-11-29 2006-04-28 Sanofi Synthelabo Indole-3-carboxamide derivatives, preparation and application in therapy
FR2854633B1 (en) * 2003-05-07 2005-06-24 Sanofi Synthelabo PIPERIDINYL-AND PIPERAZINYL-ALKYLCARBAMATES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
FR2856684B1 (en) * 2003-06-26 2008-04-11 Sanofi Synthelabo DIPHENYLPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2865205B1 (en) 2004-01-16 2006-02-24 Sanofi Synthelabo ARYLOXYALKYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF
EP1758566A2 (en) * 2004-06-22 2007-03-07 Pharmos Limited Use of cb2 receptors agonists for the treatment of huntington"s disease
NZ552670A (en) 2004-07-12 2010-02-26 Cadila Healthcare Ltd Tricyclic pyrazole derivatives as cannabinoid receptor modulators
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
EP1819338A4 (en) * 2004-11-22 2009-11-04 Threshold Pharmaceuticals Inc Tubulin binding anti cancer agents and prodrugs thereof
MX2007007573A (en) * 2004-12-21 2007-07-24 Abbott Lab 3-cycloalkylcarbonyl indoles as cannabinoid receptor ligands.
FR2893615B1 (en) * 2005-11-18 2008-03-07 Sanofi Aventis Sa 3-ACYLINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
US7875639B2 (en) 2006-05-31 2011-01-25 Abbott Laboratories Compounds as cannabinoid receptor ligands and uses thereof
US8841334B2 (en) 2006-05-31 2014-09-23 Abbvie Inc. Compounds as cannabinoid receptor ligands and uses thereof
GB0702862D0 (en) * 2007-02-14 2007-03-28 Univ Aberdeen Therapeutic compounds
CA2681586A1 (en) 2007-03-28 2008-10-09 Abbott Laboratories 1, 3-thiazol-2 (3h) -ylidene compounds as cannabinoid receptor ligands
US7872033B2 (en) * 2007-04-17 2011-01-18 Abbott Laboratories Compounds as cannabinoid receptor ligands
FR2915199B1 (en) * 2007-04-18 2010-01-22 Sanofi Aventis TRIAZOLOPYRIDINE-CARBOXAMIDE AND TRIAZOLOPYRIMIDINE-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE.
MX2009012374A (en) 2007-05-18 2009-12-01 Abbott Lab Novel compounds as cannabinoid receptor ligands.
US9193713B2 (en) * 2007-10-12 2015-11-24 Abbvie Inc. Compounds as cannabinoid receptor ligands
FR2933697B1 (en) * 2008-07-11 2010-08-13 Sanofi Aventis SUBSTITUTED 1-BENZYL-CINNOLIN-4- (1H) -ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
US8846730B2 (en) 2008-09-08 2014-09-30 Abbvie Inc. Compounds as cannabinoid receptor ligands
CA2737199A1 (en) 2008-09-16 2010-03-25 Abbott Laboratories Novel compounds as cannabinoid receptor ligands
PA8854001A1 (en) 2008-12-16 2010-07-27 Abbott Lab NEW COMPOUNDS AS CANABINOID RECEIVERS LIGANDS
FR2941696B1 (en) 2009-02-05 2011-04-15 Sanofi Aventis AZASPIRANYL-ALKYLCARBAMATES DERIVATIVES OF 5-CHAIN HETEROCYCLES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
FR2945533B1 (en) 2009-05-12 2011-05-27 Sanofi Aventis CYCLOPENTA® C! PYRROLYL-ALKYLCARBAMATE DERIVATIVES OF 5-CHAIN HETEROCYCLES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
WO2011009883A1 (en) 2009-07-23 2011-01-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Selective cb2 receptor agonists for use in the prevention or treatment of alcoholic liver disease
FR2950055A1 (en) 2009-09-17 2011-03-18 Sanofi Aventis SUBSTITUTED 3-AMINO-CINNOLIN-4 (1H) -ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
US20130178453A1 (en) * 2010-02-09 2013-07-11 Ironwood Pharmaceuticals, Inc. Cannabinoid Agonists
FR2983859B1 (en) 2011-12-12 2014-01-17 Sanofi Sa 1,3,5-TRIAZINE-2-AMINE DERIVATIVES, THEIR PREPARATION AND THEIR DIAGNOSTIC AND THERAPEUTIC USE
EP3074768A4 (en) * 2013-11-28 2017-07-19 Commonwealth Scientific and Industrial Research Organisation Method of detecting plasmodium infection
CN108794379A (en) * 2017-04-26 2018-11-13 华东师范大学 1H- indole-2-carboxamide derivatives and its preparation method and application
WO2022128050A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammation and pain

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532237A (en) * 1995-02-15 1996-07-02 Merck Frosst Canada, Inc. Indole derivatives with affinity for the cannabinoid receptor
FR2735774B1 (en) * 1995-06-21 1997-09-12 Sanofi Sa USE OF HUMAN CB2 RECEPTOR AGONIST COMPOUNDS FOR THE PREPARATION OF IMMUNOMODULATORY DRUGS, NOVEL CB2 RECEPTOR AGONIST COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EP1223929B1 (en) * 1999-10-18 2006-08-23 The University Of Connecticut Cannabimimetic indole derivatives

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