AU2001281989A1 - Novel heteroaryl derivatives and use thereof as anti-tumour agents - Google Patents
Novel heteroaryl derivatives and use thereof as anti-tumour agentsInfo
- Publication number
- AU2001281989A1 AU2001281989A1 AU2001281989A AU2001281989A AU2001281989A1 AU 2001281989 A1 AU2001281989 A1 AU 2001281989A1 AU 2001281989 A AU2001281989 A AU 2001281989A AU 2001281989 A AU2001281989 A AU 2001281989A AU 2001281989 A1 AU2001281989 A1 AU 2001281989A1
- Authority
- AU
- Australia
- Prior art keywords
- tumour agents
- heteroaryl derivatives
- novel heteroaryl
- novel
- tumour
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000259 anti-tumor Effects 0.000 title 1
- 125000001072 heteroaryl group Chemical group 0.000 title 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10035908.6 | 2000-07-21 | ||
DE10035908A DE10035908A1 (en) | 2000-07-21 | 2000-07-21 | New heteroaryl derivatives and their use as medicines |
PCT/EP2001/008262 WO2002008190A2 (en) | 2000-07-21 | 2001-07-18 | Novel heteroaryl derivatives and use thereof as anti-tumour agents |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2001281989A1 true AU2001281989A1 (en) | 2002-05-02 |
AU2001281989B2 AU2001281989B2 (en) | 2005-05-12 |
Family
ID=7649970
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU8198901A Pending AU8198901A (en) | 2000-07-21 | 2001-07-18 | Novel heteroaryl derivatives and use thereof as medicaments |
AU2001281989A Ceased AU2001281989B2 (en) | 2000-07-21 | 2001-07-18 | Novel heteroaryl derivatives and use thereof as anti-tumour agents |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU8198901A Pending AU8198901A (en) | 2000-07-21 | 2001-07-18 | Novel heteroaryl derivatives and use thereof as medicaments |
Country Status (21)
Country | Link |
---|---|
US (1) | US6638935B2 (en) |
EP (1) | EP1305289A2 (en) |
JP (1) | JP2004516243A (en) |
KR (1) | KR20030015894A (en) |
CN (1) | CN1447796A (en) |
AR (1) | AR032467A1 (en) |
AU (2) | AU8198901A (en) |
BG (1) | BG107506A (en) |
BR (1) | BR0112711A (en) |
CA (1) | CA2353353A1 (en) |
DE (1) | DE10035908A1 (en) |
HU (1) | HUP0300743A2 (en) |
IL (1) | IL153931A0 (en) |
MX (1) | MXPA03000596A (en) |
NO (1) | NO20030302L (en) |
NZ (1) | NZ524156A (en) |
PL (1) | PL361354A1 (en) |
RU (1) | RU2003105238A (en) |
SK (1) | SK1942003A3 (en) |
WO (1) | WO2002008190A2 (en) |
ZA (1) | ZA200300545B (en) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040014744A1 (en) * | 2002-04-05 | 2004-01-22 | Fortuna Haviv | Substituted pyridines having antiangiogenic activity |
MXPA04012959A (en) * | 2002-06-29 | 2005-05-16 | Zentaris Gmbh | Arylcarbonylpiperazines and heteroarylcarbonylpiperazines and the use thereof for treating benign and malignant tumour diseases. |
AU2004218260A1 (en) * | 2003-01-28 | 2004-09-16 | Aventis Pharma S.A. | N-aryl heteroaromatic products, compositions containing same and use thereof |
FR2855825B1 (en) * | 2003-06-04 | 2008-08-22 | Aventis Pharma Sa | ARYL-HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
PE20050226A1 (en) * | 2003-06-04 | 2005-05-18 | Aventis Pharma Sa | ARIL-HETEROAROMATIC PRODUCTS AND COMPOSITIONS CONTAINING THEM |
US7592466B2 (en) | 2003-10-09 | 2009-09-22 | Abbott Laboratories | Ureas having antiangiogenic activity |
FR2871157A1 (en) * | 2004-06-04 | 2005-12-09 | Aventis Pharma Sa | BIARYL AROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
EP1645556A1 (en) * | 2004-10-07 | 2006-04-12 | Boehringer Ingelheim International GmbH | Arylpiperazine-benzoylamide derivatives useful as pharmaceutical agents |
WO2008094992A2 (en) * | 2007-01-31 | 2008-08-07 | Vertex Pharmaceuticals Incorporated | 2-aminopyridine derivatives useful as kinase inhibitors |
EP2125750B1 (en) * | 2007-02-26 | 2014-05-21 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
EP2183228B1 (en) * | 2007-07-26 | 2014-08-20 | Vitae Pharmaceuticals, Inc. | CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1 |
AU2008331733A1 (en) * | 2007-11-02 | 2009-06-11 | Vertex Pharmaceuticals Incorporated | [1H- pyrazolo [3, 4-b] pyridine-4-yl] -phenyle or -pyridin-2-yle derivatives as protein kinase C-theta |
AR069207A1 (en) * | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | CYCLIC UREAS AS INHIBITORS OF THE 11 BETA - HIDROXI-ESTEROIDE DESHIDROGENASA 1 |
CA2708303A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
TW200934490A (en) * | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
CA2712500A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
WO2009102428A2 (en) * | 2008-02-11 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | 1,3-OXAZEPAN-2-ONE AND 1,3-DIAZEPAN-2-ONE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 |
EP2254872A2 (en) * | 2008-02-15 | 2010-12-01 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
JP5538356B2 (en) * | 2008-03-18 | 2014-07-02 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | Inhibitors of 11β-hydroxysteroid dehydrogenase type 1 |
CA2722427A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
CA2723039A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
JP5451752B2 (en) * | 2008-05-01 | 2014-03-26 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
EP2291370B1 (en) | 2008-05-01 | 2013-11-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
CN102131809A (en) | 2008-07-23 | 2011-07-20 | 沃泰克斯药物股份有限公司 | Tri-cyclic pyrazolopyridine kinase inhibitors |
US8569337B2 (en) | 2008-07-23 | 2013-10-29 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
ES2402087T3 (en) | 2008-07-23 | 2013-04-26 | Vertex Pharmaceuticals Incorporated | Pyrazolopyridine Kinase Inhibitors |
AU2009274567B2 (en) | 2008-07-25 | 2013-04-04 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
WO2010010157A2 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
JP2011530527A (en) * | 2008-08-06 | 2011-12-22 | バーテックス ファーマシューティカルズ インコーポレイテッド | Aminopyridine kinase inhibitor |
CA2744946A1 (en) | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
TW201039034A (en) * | 2009-04-27 | 2010-11-01 | Chunghwa Picture Tubes Ltd | Pixel structure and the method of forming the same |
US20100331320A1 (en) * | 2009-04-30 | 2010-12-30 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
US8680093B2 (en) | 2009-04-30 | 2014-03-25 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
JP5627675B2 (en) | 2009-05-06 | 2014-11-19 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | Pyrazolopyridine |
WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
WO2011002910A1 (en) | 2009-07-01 | 2011-01-06 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
CA2787079A1 (en) | 2010-01-27 | 2011-08-04 | Vertex Pharmaceuticals Incorporated | Pyrazolopyrazine kinase inhibitors |
JP5769733B2 (en) | 2010-01-27 | 2015-08-26 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | Pyrazolopyridine kinase inhibitor |
WO2011094290A1 (en) | 2010-01-27 | 2011-08-04 | Vertex Pharmaceuticals Incorporated | Pyrazolopyrimidine kinase inhibitors |
US8933072B2 (en) | 2010-06-16 | 2015-01-13 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
JP5813106B2 (en) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Azaspirohexanone as an inhibitor of 11-β-HSD1 for the treatment of metabolic disorders |
EP2635268A1 (en) | 2010-11-02 | 2013-09-11 | Boehringer Ingelheim International GmbH | Pharmaceutical combinations for the treatment of metabolic disorders |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE791501A (en) * | 1971-11-19 | 1973-05-17 | Albert Ag Chem Werke | N, N'-DISUBSTITUTED CYCLIC DIAMINES AND THEIR PREPARATION PROCESS |
JPS50151886A (en) * | 1974-05-29 | 1975-12-06 | ||
HU175075B (en) * | 1977-06-30 | 1980-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for preparing pyridine-carboxylic acid piperazides |
EP0040793B1 (en) * | 1980-05-22 | 1985-08-28 | Masayuki Ishikawa | Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof |
US4937246A (en) * | 1987-11-25 | 1990-06-26 | Takeda Chemical Industries, Ltd. | PAF antagonist, 1,4-disubstituted piperazine compounds and production thereof |
MX16687A (en) * | 1988-07-07 | 1994-01-31 | Ciba Geigy Ag | BIARILE COMPOUNDS AND PROCEDURE FOR THE PREPARATION. |
EP0703905A1 (en) * | 1993-06-18 | 1996-04-03 | Merck & Co. Inc. | Inhibitors of farnesyl-protein transferase |
JP2978967B2 (en) * | 1995-01-11 | 1999-11-15 | 三進製藥株式會社 | Novel piperazine derivative, method for producing the same, and composition containing the same |
EP0813525B9 (en) * | 1995-03-10 | 2004-02-04 | Berlex Laboratories, Inc. | Benzamidine derivatives their preparation and their use as anti-coagulants |
WO1998000402A1 (en) * | 1996-06-29 | 1998-01-08 | Samjin Pharmaceutical Co., Ltd. | Piperazine derivatives and process for the preparation thereof |
ES2125206B1 (en) * | 1997-07-21 | 1999-11-16 | Esteve Labor Dr | DERIVATIVES OF ACIL-PIPERAZINIL-PIRIMIDINAS, ITS PREPARATION AND ITS APPLICATION AS MEDICINES. |
US6166203A (en) * | 1998-02-26 | 2000-12-26 | Neurogen Corporation | Heterocyclic amino substituted heteroaryl fused pyridines; GABA brain receptor ligands |
CA2342251A1 (en) * | 1998-08-28 | 2000-03-09 | Scios Inc. | Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase |
WO2000052001A1 (en) * | 1999-03-03 | 2000-09-08 | Samjin Pharmaceutical Co., Ltd. | Piperazine derivatives and process for the preparation thereof |
US6469006B1 (en) * | 1999-06-15 | 2002-10-22 | Bristol-Myers Squibb Company | Antiviral indoleoxoacetyl piperazine derivatives |
DE60022386T2 (en) * | 1999-12-16 | 2006-06-22 | Schering Corp. | SUBSTITUTED IMIDAZOLE AS NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS |
-
2000
- 2000-07-21 DE DE10035908A patent/DE10035908A1/en not_active Withdrawn
-
2001
- 2001-07-18 PL PL36135401A patent/PL361354A1/en unknown
- 2001-07-18 KR KR10-2003-7000880A patent/KR20030015894A/en not_active Application Discontinuation
- 2001-07-18 IL IL15393101A patent/IL153931A0/en unknown
- 2001-07-18 SK SK194-2003A patent/SK1942003A3/en not_active Application Discontinuation
- 2001-07-18 CN CN01814312A patent/CN1447796A/en active Pending
- 2001-07-18 MX MXPA03000596A patent/MXPA03000596A/en unknown
- 2001-07-18 WO PCT/EP2001/008262 patent/WO2002008190A2/en active IP Right Grant
- 2001-07-18 JP JP2002514097A patent/JP2004516243A/en not_active Withdrawn
- 2001-07-18 BR BR0112711-0A patent/BR0112711A/en not_active IP Right Cessation
- 2001-07-18 NZ NZ524156A patent/NZ524156A/en unknown
- 2001-07-18 HU HU0300743A patent/HUP0300743A2/en unknown
- 2001-07-18 AU AU8198901A patent/AU8198901A/en active Pending
- 2001-07-18 EP EP01960509A patent/EP1305289A2/en not_active Withdrawn
- 2001-07-18 RU RU2003105238/04A patent/RU2003105238A/en not_active Application Discontinuation
- 2001-07-18 AU AU2001281989A patent/AU2001281989B2/en not_active Ceased
- 2001-07-20 US US09/910,139 patent/US6638935B2/en not_active Expired - Fee Related
- 2001-07-20 AR ARP010103479A patent/AR032467A1/en unknown
- 2001-07-20 CA CA002353353A patent/CA2353353A1/en not_active Abandoned
-
2002
- 2002-01-21 ZA ZA200300545A patent/ZA200300545B/en unknown
-
2003
- 2003-01-20 NO NO20030302A patent/NO20030302L/en unknown
- 2003-01-30 BG BG107506A patent/BG107506A/en unknown
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