IL150259A0 - Alkylnyl-substituted propionic acid derivatives and their use against diabetes and obesity - Google Patents

Alkylnyl-substituted propionic acid derivatives and their use against diabetes and obesity

Info

Publication number
IL150259A0
IL150259A0 IL15025901A IL15025901A IL150259A0 IL 150259 A0 IL150259 A0 IL 150259A0 IL 15025901 A IL15025901 A IL 15025901A IL 15025901 A IL15025901 A IL 15025901A IL 150259 A0 IL150259 A0 IL 150259A0
Authority
IL
Israel
Prior art keywords
alkylnyl
obesity
propionic acid
acid derivatives
use against
Prior art date
Application number
IL15025901A
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL150259A0 publication Critical patent/IL150259A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
IL15025901A 2000-01-28 2001-01-26 Alkylnyl-substituted propionic acid derivatives and their use against diabetes and obesity IL150259A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200000137 2000-01-28
DKPA200001065 2000-07-07
DKPA200001593 2000-10-25
PCT/DK2001/000057 WO2001055086A1 (en) 2000-01-28 2001-01-26 Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity

Publications (1)

Publication Number Publication Date
IL150259A0 true IL150259A0 (en) 2002-12-01

Family

ID=27222337

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15025901A IL150259A0 (en) 2000-01-28 2001-01-26 Alkylnyl-substituted propionic acid derivatives and their use against diabetes and obesity

Country Status (13)

Country Link
EP (1) EP1254102A1 (en)
JP (1) JP2003520839A (en)
KR (1) KR20020090211A (en)
CN (1) CN1396904A (en)
AU (1) AU2831801A (en)
BR (1) BR0107902A (en)
CA (1) CA2396372A1 (en)
HU (1) HUP0204247A3 (en)
IL (1) IL150259A0 (en)
MX (1) MXPA02007295A (en)
NO (1) NO20023567L (en)
PL (1) PL357017A1 (en)
WO (1) WO2001055086A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI311133B (en) * 2001-04-20 2009-06-21 Eisai R&D Man Co Ltd Carboxylic acid derivativeand the salt thereof
JPWO2003016265A1 (en) 2001-08-17 2004-12-02 エーザイ株式会社 Cyclic compounds and PPAR agonists
RU2004114875A (en) * 2001-10-17 2005-09-10 Ново Нордиск А/С (DK) DICARBOXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND THERAPEUTIC USE
US7220877B2 (en) 2001-10-17 2007-05-22 Novo Nordisk A/S Compounds, their preparation and use
ITRM20020014A1 (en) * 2002-01-15 2003-07-15 Sigma Tau Ind Farmaceuti DERIVATIVES OF A-PHENYLTHIOCARBOXYL AND A-PHYLYOXYCARBOXYL ACIDS USEFUL FOR THE TREATMENT OF DISEASES THAT RESPOND TO THE ACTIVATION OF
BR0314335A (en) * 2002-09-05 2005-07-26 Novo Nordisk As Compound, use thereof, pharmaceutical composition, and methods for treating and / or preventing nuclear receptor-mediated conditions, and of type i diabetes, type ii diabetes, impaired glucose tolerance, insulin resistance, or obesity.
WO2005105736A1 (en) 2004-05-05 2005-11-10 Novo Nordisk A/S Novel compounds, their preparation and use
WO2006000567A2 (en) * 2004-06-28 2006-01-05 Novo Nordisk A/S Use of glp-1 receptor agonists and / or dpp-iv inhibitors in combination with proton pump inhibitors and ppar agonists for the preparation of a medicament for the treatment of diabetes type i i and impaired pancreatic beta-cell function
EP2386540A1 (en) 2005-12-22 2011-11-16 High Point Pharmaceuticals, LLC Novel compounds, their preparation and use
US10307480B2 (en) 2014-11-06 2019-06-04 Scholar Rock, Inc. Anti-pro/latent-myostatin antibodies and uses thereof
CN113896789A (en) 2015-09-15 2022-01-07 供石公司 Anti-pro/latent myostatin antibodies and uses thereof
HUE061656T2 (en) * 2017-01-06 2023-07-28 Scholar Rock Inc Treating metabolic diseases by inhibiting myostatin activation
US11267795B2 (en) 2020-07-22 2022-03-08 Reneo Pharmaceuticals, Inc. Crystalline PPAR-delta agonist
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU678974B2 (en) * 1992-07-03 1997-06-19 Smithkline Beecham Plc Heterocyclic compounds as pharmaceutical
FR2707989B1 (en) * 1993-07-22 1995-10-13 Pf Medicament New silylated benzylamine derivatives, their salts, their manufacturing processes and the pharmaceutical compositions containing them.
WO1996004261A1 (en) * 1994-07-29 1996-02-15 Smithkline Beecham Plc Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes
GB9600464D0 (en) * 1996-01-09 1996-03-13 Smithkline Beecham Plc Novel method
GB9606805D0 (en) * 1996-03-30 1996-06-05 Glaxo Wellcome Inc Medicaments

Also Published As

Publication number Publication date
AU2831801A (en) 2001-08-07
MXPA02007295A (en) 2002-11-29
HUP0204247A3 (en) 2003-10-28
NO20023567D0 (en) 2002-07-26
CN1396904A (en) 2003-02-12
BR0107902A (en) 2002-11-05
CA2396372A1 (en) 2001-08-02
WO2001055086A1 (en) 2001-08-02
HUP0204247A2 (en) 2003-04-28
JP2003520839A (en) 2003-07-08
NO20023567L (en) 2002-09-25
KR20020090211A (en) 2002-11-30
PL357017A1 (en) 2004-07-12
EP1254102A1 (en) 2002-11-06

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