HUT70528A - 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents and process for production thereof - Google Patents
2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents and process for production thereof Download PDFInfo
- Publication number
- HUT70528A HUT70528A HU9400136A HU9400136A HUT70528A HU T70528 A HUT70528 A HU T70528A HU 9400136 A HU9400136 A HU 9400136A HU 9400136 A HU9400136 A HU 9400136A HU T70528 A HUT70528 A HU T70528A
- Authority
- HU
- Hungary
- Prior art keywords
- alkyl
- amino
- hydroxy
- formula
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73157791A | 1991-07-17 | 1991-07-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
HU9400136D0 HU9400136D0 (en) | 1994-05-30 |
HUT70528A true HUT70528A (en) | 1995-10-30 |
Family
ID=24940103
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9400136A HUT70528A (en) | 1991-07-17 | 1992-06-19 | 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents and process for production thereof |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0594729A1 (ko) |
JP (1) | JP2571904B2 (ko) |
KR (1) | KR0165003B1 (ko) |
CN (1) | CN1043759C (ko) |
AU (1) | AU655840B2 (ko) |
BR (1) | BR9206272A (ko) |
CA (1) | CA2113568A1 (ko) |
CZ (1) | CZ284133B6 (ko) |
EG (1) | EG20048A (ko) |
FI (2) | FI940192A (ko) |
HU (1) | HUT70528A (ko) |
IE (1) | IE922311A1 (ko) |
IL (1) | IL102473A (ko) |
MX (1) | MX9204190A (ko) |
NO (1) | NO180445C (ko) |
NZ (1) | NZ243580A (ko) |
PL (1) | PL169884B1 (ko) |
PT (1) | PT100689B (ko) |
RU (1) | RU2065859C1 (ko) |
TW (1) | TW201732B (ko) |
WO (1) | WO1993002052A1 (ko) |
ZA (1) | ZA925306B (ko) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5436255A (en) * | 1992-07-23 | 1995-07-25 | Pfizer Inc. | Method of treating diseases susceptable to treatment by blocking NMDA-receptors |
BR9307331A (pt) * | 1992-10-30 | 1999-05-25 | Pfizer | Compostos neuroprotetores 3,4-dihidro-2(1ho-quinolona |
US5498610A (en) * | 1992-11-06 | 1996-03-12 | Pfizer Inc. | Neuroprotective indolone and related derivatives |
ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
ZA9610736B (en) * | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
WO2000061558A1 (fr) * | 1999-04-09 | 2000-10-19 | Mochida Pharmaceutical Co., Ltd. | Remedes pour douleurs neurogenes |
US6369076B1 (en) | 1999-10-29 | 2002-04-09 | Merck & Co. Inc. | 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists |
US6489477B1 (en) | 1999-10-29 | 2002-12-03 | Merck & Co., Inc. | 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists |
US6316474B1 (en) | 1999-10-29 | 2001-11-13 | Merck & Co., Inc. | 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists |
US6495561B2 (en) | 1999-10-29 | 2002-12-17 | Merck & Co., Inc. | 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists |
US6291499B1 (en) | 1999-10-29 | 2001-09-18 | Merck & Co., Inc. | 2-cyclohexyl benzimidazole NMDA/NR2B antagonists |
US6380205B1 (en) | 1999-10-29 | 2002-04-30 | Merck & Co., Inc. | 2-cyclohexyl quinazoline NMDA/NR2B antagonists |
WO2001030330A2 (en) | 1999-10-29 | 2001-05-03 | Merck Sharp & Dohme Limited | Method to treat pain utilizing benzimidazole nmda/nr2b antagonists |
US6476041B1 (en) | 1999-10-29 | 2002-11-05 | Merck & Co., Inc. | 1,4 substituted piperidinyl NMDA/NR2B antagonists |
US6432976B1 (en) | 1999-10-29 | 2002-08-13 | Merck & Co., Inc. | 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists |
KR100849839B1 (ko) | 2001-02-23 | 2008-08-01 | 머크 앤드 캄파니 인코포레이티드 | N-치환된 비-아릴-헤테로사이클릭 nmda/nr2b 길항제 및 이를 포함하는 약제학적 조성물 |
CA2443108A1 (en) | 2001-04-03 | 2002-10-17 | Merck & Co. Inc. | N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists |
CA2507509A1 (en) | 2002-11-25 | 2004-06-10 | Mochida Pharmaceutical Co., Ltd. | Therapeutic agent for respiratory disease containing 4-hydroxypiperidine derivative as active ingredient |
EP1673367A1 (en) * | 2003-10-08 | 2006-06-28 | Pfizer, Inc. | Fused lactam compounds |
TWI409289B (zh) | 2010-09-02 | 2013-09-21 | Taiwan Union Technology Corp | 由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
FR2546166B1 (fr) * | 1983-05-19 | 1985-10-25 | Synthelabo | Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique |
FR2640266B2 (fr) * | 1988-07-12 | 1992-07-10 | Synthelabo | Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique |
ES2098248T3 (es) * | 1989-05-17 | 1997-05-01 | Pfizer | Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos. |
PL169267B1 (pl) * | 1990-05-10 | 1996-06-28 | Pfizer | Sposób wytwarzania nowej racemicznej lub optycznie czynnej pochodnej indolu PL PL PL PL PL PL |
-
1992
- 1992-06-19 BR BR9206272A patent/BR9206272A/pt not_active Application Discontinuation
- 1992-06-19 RU RU9294012366A patent/RU2065859C1/ru active
- 1992-06-19 EP EP92915510A patent/EP0594729A1/en not_active Ceased
- 1992-06-19 PL PL92302290A patent/PL169884B1/pl unknown
- 1992-06-19 WO PCT/US1992/004973 patent/WO1993002052A1/en not_active Application Discontinuation
- 1992-06-19 CA CA002113568A patent/CA2113568A1/en not_active Abandoned
- 1992-06-19 AU AU23225/92A patent/AU655840B2/en not_active Ceased
- 1992-06-19 HU HU9400136A patent/HUT70528A/hu unknown
- 1992-06-19 CZ CS924008A patent/CZ284133B6/cs not_active IP Right Cessation
- 1992-06-19 JP JP5502784A patent/JP2571904B2/ja not_active Expired - Lifetime
- 1992-06-23 TW TW081104921A patent/TW201732B/zh active
- 1992-07-12 IL IL102473A patent/IL102473A/xx not_active IP Right Cessation
- 1992-07-15 PT PT100689A patent/PT100689B/pt not_active IP Right Cessation
- 1992-07-16 ZA ZA925306A patent/ZA925306B/xx unknown
- 1992-07-16 EG EG39792A patent/EG20048A/xx active
- 1992-07-16 MX MX9204190A patent/MX9204190A/es unknown
- 1992-07-16 IE IE231192A patent/IE922311A1/en not_active Application Discontinuation
- 1992-07-16 CN CN92105921A patent/CN1043759C/zh not_active Expired - Fee Related
- 1992-07-16 NZ NZ243580A patent/NZ243580A/en unknown
-
1994
- 1994-01-14 FI FI940192A patent/FI940192A/fi unknown
- 1994-01-14 NO NO940144A patent/NO180445C/no not_active IP Right Cessation
- 1994-01-15 KR KR1019940700124A patent/KR0165003B1/ko not_active IP Right Cessation
-
1998
- 1998-09-11 FI FI981956A patent/FI981956A0/fi unknown
Also Published As
Publication number | Publication date |
---|---|
BR9206272A (pt) | 1995-04-11 |
FI940192A0 (fi) | 1994-01-14 |
CN1043759C (zh) | 1999-06-23 |
NO940144D0 (no) | 1994-01-14 |
AU655840B2 (en) | 1995-01-12 |
TW201732B (ko) | 1993-03-11 |
IE922311A1 (en) | 1993-01-27 |
KR0165003B1 (en) | 1999-01-15 |
IL102473A0 (en) | 1993-01-14 |
ZA925306B (en) | 1994-01-17 |
NO180445B (no) | 1997-01-13 |
NO940144L (no) | 1994-01-14 |
FI981956A (fi) | 1998-09-11 |
NO180445C (no) | 1997-04-23 |
HU9400136D0 (en) | 1994-05-30 |
CZ400892A3 (en) | 1994-03-16 |
IL102473A (en) | 1997-07-13 |
PL169884B1 (pl) | 1996-09-30 |
CN1068566A (zh) | 1993-02-03 |
AU2322592A (en) | 1993-02-23 |
WO1993002052A1 (en) | 1993-02-04 |
FI940192A (fi) | 1994-01-14 |
CZ284133B6 (cs) | 1998-08-12 |
EP0594729A1 (en) | 1994-05-04 |
JP2571904B2 (ja) | 1997-01-16 |
NZ243580A (en) | 1994-10-26 |
FI981956A0 (fi) | 1998-09-11 |
RU2065859C1 (ru) | 1996-08-27 |
PT100689A (pt) | 1993-10-29 |
MX9204190A (es) | 1993-01-01 |
CA2113568A1 (en) | 1993-02-04 |
JPH06504293A (ja) | 1994-05-19 |
EG20048A (en) | 1997-03-27 |
PT100689B (pt) | 1999-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUT70528A (en) | 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents and process for production thereof | |
US6787535B2 (en) | Indole derivatives with 5HT6 receptor affinity | |
US4855298A (en) | 6-Halo-1,2,3,4-tetrahydroquinazoline-4-spiro-4-imidazolidine-2,2'5'-triones useful for the treatment and prophylaxis of diabetic complications | |
JPH02275853A (ja) | アリールピペリジン誘導体 | |
HU225049B1 (en) | Heteroaryl-amines as acetyl-cholinesterase inhibitors, pharmaceutical compositions comprising them and process for their preparation | |
FR2662696A2 (fr) | Antagonistes de la serotonine, leur preparation et medicaments les contenant. | |
KR100201509B1 (ko) | 1-(피리도(3,4-b-1,4-옥사지닐-4일-)-1h-인돌, 이를 위한 중간체, 이의 제조방법 및 이를 포함하는 약제학적 조성물 | |
HU196194B (en) | Process for producing new 1-4 disubstituted piperazines and pharmaceuticals comprising the compounds | |
EP0726898B1 (en) | Phenylindole compounds | |
GB1571242A (en) | 3,3 - dichloro - 2 - azetidinone derivatives | |
HU184238B (en) | Process for preparing piperidino-propyl-derivatives and pharmaceutical compositions containing thereof | |
WO1983004254A1 (en) | Piperazine derivative compounds, production method thereof and drugs containing them | |
US5077295A (en) | Antipsychoic 4-(4-(3-benzisothiazolyl)-1-piperazinyl)buytl bridged bicycle imides | |
US6255322B1 (en) | 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents | |
GB1580238A (en) | 1,3 - benzodithiolanes | |
AU680562B2 (en) | Tricyclic compounds having affinity for the 5-ht1a receptor | |
IE902499A1 (en) | Novel heterocyclic compounds containing nitrogen and sulfur,¹pharmaceutical compositions containing them and process for¹preparing same | |
EP0853619A1 (en) | Disubstituted piperidine derivatives | |
HU211665A9 (hu) | Az átmeneti oltalom az 1-19. igénypontokra vonatkozik. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
DFC4 | Cancellation of temporary protection due to refusal |