PT100689A - Derivados de 2-(4-hidroxipiperidino)-1-alcanol como agentes anti-isquemicos - Google Patents
Derivados de 2-(4-hidroxipiperidino)-1-alcanol como agentes anti-isquemicosInfo
- Publication number
- PT100689A PT100689A PT100689A PT10068992A PT100689A PT 100689 A PT100689 A PT 100689A PT 100689 A PT100689 A PT 100689A PT 10068992 A PT10068992 A PT 10068992A PT 100689 A PT100689 A PT 100689A
- Authority
- PT
- Portugal
- Prior art keywords
- hydroxipipididine
- alcanol
- derivatives
- ischemic agents
- ischemic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73157791A | 1991-07-17 | 1991-07-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT100689A true PT100689A (pt) | 1993-10-29 |
| PT100689B PT100689B (pt) | 1999-06-30 |
Family
ID=24940103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT100689A PT100689B (pt) | 1991-07-17 | 1992-07-15 | Derivados de 2-(4-hidroxipiperidino)-1-alcanol como agentes anti-isquemicos |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0594729A1 (pt) |
| JP (1) | JP2571904B2 (pt) |
| KR (1) | KR0165003B1 (pt) |
| CN (1) | CN1043759C (pt) |
| AU (1) | AU655840B2 (pt) |
| BR (1) | BR9206272A (pt) |
| CA (1) | CA2113568A1 (pt) |
| CZ (1) | CZ284133B6 (pt) |
| EG (1) | EG20048A (pt) |
| FI (2) | FI940192A (pt) |
| HU (1) | HUT70528A (pt) |
| IE (1) | IE922311A1 (pt) |
| IL (1) | IL102473A (pt) |
| MX (1) | MX9204190A (pt) |
| NO (1) | NO180445C (pt) |
| NZ (1) | NZ243580A (pt) |
| PL (1) | PL169884B1 (pt) |
| PT (1) | PT100689B (pt) |
| RU (1) | RU2065859C1 (pt) |
| TW (1) | TW201732B (pt) |
| WO (1) | WO1993002052A1 (pt) |
| ZA (1) | ZA925306B (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5436255A (en) * | 1992-07-23 | 1995-07-25 | Pfizer Inc. | Method of treating diseases susceptable to treatment by blocking NMDA-receptors |
| JP2695292B2 (ja) * | 1992-10-30 | 1997-12-24 | フアイザー・インコーポレイテツド | 神経保護性３，４−ジヒドロ−（１ｈ）−キノロン化合物 |
| US5498610A (en) * | 1992-11-06 | 1996-03-12 | Pfizer Inc. | Neuroprotective indolone and related derivatives |
| ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610736B (en) * | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| EP1182193A4 (en) * | 1999-04-09 | 2002-09-11 | Mochida Pharm Co Ltd | REMEDIES FOR NEUROGENIC PAIN |
| US6495561B2 (en) | 1999-10-29 | 2002-12-17 | Merck & Co., Inc. | 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists |
| US6432976B1 (en) | 1999-10-29 | 2002-08-13 | Merck & Co., Inc. | 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists |
| US6291499B1 (en) | 1999-10-29 | 2001-09-18 | Merck & Co., Inc. | 2-cyclohexyl benzimidazole NMDA/NR2B antagonists |
| US6369076B1 (en) | 1999-10-29 | 2002-04-09 | Merck & Co. Inc. | 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists |
| US6476041B1 (en) | 1999-10-29 | 2002-11-05 | Merck & Co., Inc. | 1,4 substituted piperidinyl NMDA/NR2B antagonists |
| US6380205B1 (en) | 1999-10-29 | 2002-04-30 | Merck & Co., Inc. | 2-cyclohexyl quinazoline NMDA/NR2B antagonists |
| US6316474B1 (en) | 1999-10-29 | 2001-11-13 | Merck & Co., Inc. | 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists |
| US6489477B1 (en) | 1999-10-29 | 2002-12-03 | Merck & Co., Inc. | 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists |
| EP1235572A2 (en) | 1999-10-29 | 2002-09-04 | MERCK SHARP & DOHME LTD. | Method to treat pain utilizing benzimidazole nmda/nr2b antagonists |
| ATE324371T1 (de) | 2001-02-23 | 2006-05-15 | Merck & Co Inc | N-substituierte heterocyclische nichtaryl- nmda/nr2b-antagonisten |
| CA2443108A1 (en) | 2001-04-03 | 2002-10-17 | Merck & Co. Inc. | N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists |
| AU2003302416A1 (en) | 2002-11-25 | 2004-06-18 | Mochida Pharmaceutical Co., Ltd. | Therapeutic agent for respiratory disease containing 4-hydroxypiperidine derivative as active ingredient |
| MXPA06003748A (es) * | 2003-10-08 | 2006-06-14 | Pfizer | Compuestos de lactama condensada. |
| TWI409289B (zh) | 2010-09-02 | 2013-09-21 | Taiwan Union Technology Corp | 由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
| FR2546166B1 (fr) * | 1983-05-19 | 1985-10-25 | Synthelabo | Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique |
| FR2640266B2 (fr) * | 1988-07-12 | 1992-07-10 | Synthelabo | Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique |
| ES2098248T3 (es) * | 1989-05-17 | 1997-05-01 | Pfizer | Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos. |
| ATE192149T1 (de) * | 1990-05-10 | 2000-05-15 | Pfizer | Neuroprotective indolone und verwandte derivate |
-
1992
- 1992-06-19 EP EP92915510A patent/EP0594729A1/en not_active Ceased
- 1992-06-19 PL PL92302290A patent/PL169884B1/pl unknown
- 1992-06-19 WO PCT/US1992/004973 patent/WO1993002052A1/en not_active Application Discontinuation
- 1992-06-19 HU HU9400136A patent/HUT70528A/hu unknown
- 1992-06-19 RU RU9294012366A patent/RU2065859C1/ru active
- 1992-06-19 BR BR9206272A patent/BR9206272A/pt not_active Application Discontinuation
- 1992-06-19 CZ CS924008A patent/CZ284133B6/cs not_active IP Right Cessation
- 1992-06-19 JP JP5502784A patent/JP2571904B2/ja not_active Expired - Lifetime
- 1992-06-19 CA CA002113568A patent/CA2113568A1/en not_active Abandoned
- 1992-06-19 AU AU23225/92A patent/AU655840B2/en not_active Ceased
- 1992-06-23 TW TW081104921A patent/TW201732B/zh active
- 1992-07-12 IL IL102473A patent/IL102473A/xx not_active IP Right Cessation
- 1992-07-15 PT PT100689A patent/PT100689B/pt not_active IP Right Cessation
- 1992-07-16 NZ NZ243580A patent/NZ243580A/en unknown
- 1992-07-16 IE IE231192A patent/IE922311A1/en not_active Application Discontinuation
- 1992-07-16 MX MX9204190A patent/MX9204190A/es unknown
- 1992-07-16 ZA ZA925306A patent/ZA925306B/xx unknown
- 1992-07-16 CN CN92105921A patent/CN1043759C/zh not_active Expired - Fee Related
- 1992-07-16 EG EG39792A patent/EG20048A/xx active
-
1994
- 1994-01-14 FI FI940192A patent/FI940192A/fi unknown
- 1994-01-14 NO NO940144A patent/NO180445C/no not_active IP Right Cessation
- 1994-01-15 KR KR1019940700124A patent/KR0165003B1/ko not_active IP Right Cessation
-
1998
- 1998-09-11 FI FI981956A patent/FI981956A0/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA925306B (en) | 1994-01-17 |
| HUT70528A (en) | 1995-10-30 |
| IL102473A (en) | 1997-07-13 |
| WO1993002052A1 (en) | 1993-02-04 |
| NO180445B (no) | 1997-01-13 |
| AU655840B2 (en) | 1995-01-12 |
| CZ284133B6 (cs) | 1998-08-12 |
| CN1043759C (zh) | 1999-06-23 |
| RU2065859C1 (ru) | 1996-08-27 |
| AU2322592A (en) | 1993-02-23 |
| JP2571904B2 (ja) | 1997-01-16 |
| JPH06504293A (ja) | 1994-05-19 |
| CA2113568A1 (en) | 1993-02-04 |
| KR0165003B1 (en) | 1999-01-15 |
| HU9400136D0 (en) | 1994-05-30 |
| IL102473A0 (en) | 1993-01-14 |
| CZ400892A3 (en) | 1994-03-16 |
| FI940192A0 (fi) | 1994-01-14 |
| FI981956A (fi) | 1998-09-11 |
| NO940144L (no) | 1994-01-14 |
| NO180445C (no) | 1997-04-23 |
| NZ243580A (en) | 1994-10-26 |
| FI981956A0 (fi) | 1998-09-11 |
| FI940192A (fi) | 1994-01-14 |
| MX9204190A (es) | 1993-01-01 |
| IE922311A1 (en) | 1993-01-27 |
| NO940144D0 (no) | 1994-01-14 |
| PL169884B1 (pl) | 1996-09-30 |
| CN1068566A (zh) | 1993-02-03 |
| TW201732B (pt) | 1993-03-11 |
| EG20048A (en) | 1997-03-27 |
| BR9206272A (pt) | 1995-04-11 |
| EP0594729A1 (en) | 1994-05-04 |
| PT100689B (pt) | 1999-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19930421 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990316 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20010930 |