FI981956A - 2-(4-hydroksipiperidino)-1-alkanolijohdannaisia verettömyyden vastaisia aineina - Google Patents
2-(4-hydroksipiperidino)-1-alkanolijohdannaisia verettömyyden vastaisia aineina Download PDFInfo
- Publication number
- FI981956A FI981956A FI981956A FI981956A FI981956A FI 981956 A FI981956 A FI 981956A FI 981956 A FI981956 A FI 981956A FI 981956 A FI981956 A FI 981956A FI 981956 A FI981956 A FI 981956A
- Authority
- FI
- Finland
- Prior art keywords
- hydroxypiperidino
- antihypertensives
- alkanol derivatives
- alkanol
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73157791A | 1991-07-17 | 1991-07-17 | |
PCT/US1992/004973 WO1993002052A1 (en) | 1991-07-17 | 1992-06-19 | 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
FI981956A true FI981956A (fi) | 1998-09-11 |
FI981956A0 FI981956A0 (fi) | 1998-09-11 |
Family
ID=24940103
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI940192A FI940192A0 (fi) | 1991-07-17 | 1994-01-14 | 2-(4-hydroksipiperidino)-1-alkonolijohdannaisia verettömyyden vastaisina aineina |
FI981956A FI981956A0 (fi) | 1991-07-17 | 1998-09-11 | 2-(4-hydroksipiperidino)-1-alkanolijohdannaisia verettömyyden vastaisia aineina |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI940192A FI940192A0 (fi) | 1991-07-17 | 1994-01-14 | 2-(4-hydroksipiperidino)-1-alkonolijohdannaisia verettömyyden vastaisina aineina |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0594729A1 (fi) |
JP (1) | JP2571904B2 (fi) |
KR (1) | KR0165003B1 (fi) |
CN (1) | CN1043759C (fi) |
AU (1) | AU655840B2 (fi) |
BR (1) | BR9206272A (fi) |
CA (1) | CA2113568A1 (fi) |
CZ (1) | CZ284133B6 (fi) |
EG (1) | EG20048A (fi) |
FI (2) | FI940192A0 (fi) |
HU (1) | HUT70528A (fi) |
IE (1) | IE922311A1 (fi) |
IL (1) | IL102473A (fi) |
MX (1) | MX9204190A (fi) |
NO (1) | NO180445C (fi) |
NZ (1) | NZ243580A (fi) |
PL (1) | PL169884B1 (fi) |
PT (1) | PT100689B (fi) |
RU (1) | RU2065859C1 (fi) |
TW (1) | TW201732B (fi) |
WO (1) | WO1993002052A1 (fi) |
ZA (1) | ZA925306B (fi) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5436255A (en) * | 1992-07-23 | 1995-07-25 | Pfizer Inc. | Method of treating diseases susceptable to treatment by blocking NMDA-receptors |
CZ280669B6 (cs) * | 1992-10-30 | 1996-03-13 | Pfizer Inc. | Deriváty 3,4-dihydro-2(1H)-chinolonu a farmaceutický prostředek na jejich bázi |
US5498610A (en) * | 1992-11-06 | 1996-03-12 | Pfizer Inc. | Neuroprotective indolone and related derivatives |
ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
ZA9610736B (en) | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
CA2369695A1 (en) * | 1999-04-09 | 2000-10-19 | Manabu Itoh | Agent for treating neuropathic pain |
WO2001030330A2 (en) | 1999-10-29 | 2001-05-03 | Merck Sharp & Dohme Limited | Method to treat pain utilizing benzimidazole nmda/nr2b antagonists |
US6291499B1 (en) | 1999-10-29 | 2001-09-18 | Merck & Co., Inc. | 2-cyclohexyl benzimidazole NMDA/NR2B antagonists |
US6369076B1 (en) | 1999-10-29 | 2002-04-09 | Merck & Co. Inc. | 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists |
US6380205B1 (en) | 1999-10-29 | 2002-04-30 | Merck & Co., Inc. | 2-cyclohexyl quinazoline NMDA/NR2B antagonists |
US6432976B1 (en) | 1999-10-29 | 2002-08-13 | Merck & Co., Inc. | 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists |
US6489477B1 (en) | 1999-10-29 | 2002-12-03 | Merck & Co., Inc. | 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists |
US6476041B1 (en) | 1999-10-29 | 2002-11-05 | Merck & Co., Inc. | 1,4 substituted piperidinyl NMDA/NR2B antagonists |
US6316474B1 (en) | 1999-10-29 | 2001-11-13 | Merck & Co., Inc. | 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists |
US6495561B2 (en) | 1999-10-29 | 2002-12-17 | Merck & Co., Inc. | 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists |
US7217716B2 (en) | 2001-02-23 | 2007-05-15 | Merck & Co., Inc. | N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists |
WO2002080928A1 (en) | 2001-04-03 | 2002-10-17 | Merck & Co., Inc. | N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists |
CA2507509A1 (en) | 2002-11-25 | 2004-06-10 | Mochida Pharmaceutical Co., Ltd. | Therapeutic agent for respiratory disease containing 4-hydroxypiperidine derivative as active ingredient |
JP2007508288A (ja) * | 2003-10-08 | 2007-04-05 | ファイザー株式会社 | 縮合ラクタム化合物 |
TWI409289B (zh) | 2010-09-02 | 2013-09-21 | Taiwan Union Technology Corp | 由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
FR2546166B1 (fr) * | 1983-05-19 | 1985-10-25 | Synthelabo | Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique |
FR2640266B2 (fr) * | 1988-07-12 | 1992-07-10 | Synthelabo | Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique |
EP0398578B1 (en) * | 1989-05-17 | 1997-03-12 | Pfizer Inc. | 2-piperidino-1-alkanol derivatives as antiischemic agents |
DK0554247T3 (da) * | 1990-05-10 | 2000-08-07 | Pfizer | Neurobeskyttende indolon og beslægtede derivater |
-
1992
- 1992-06-19 HU HU9400136A patent/HUT70528A/hu unknown
- 1992-06-19 EP EP92915510A patent/EP0594729A1/en not_active Ceased
- 1992-06-19 JP JP5502784A patent/JP2571904B2/ja not_active Expired - Lifetime
- 1992-06-19 PL PL92302290A patent/PL169884B1/pl unknown
- 1992-06-19 RU RU9294012366A patent/RU2065859C1/ru active
- 1992-06-19 BR BR9206272A patent/BR9206272A/pt not_active Application Discontinuation
- 1992-06-19 CA CA002113568A patent/CA2113568A1/en not_active Abandoned
- 1992-06-19 CZ CS924008A patent/CZ284133B6/cs not_active IP Right Cessation
- 1992-06-19 AU AU23225/92A patent/AU655840B2/en not_active Ceased
- 1992-06-19 WO PCT/US1992/004973 patent/WO1993002052A1/en not_active Application Discontinuation
- 1992-06-23 TW TW081104921A patent/TW201732B/zh active
- 1992-07-12 IL IL102473A patent/IL102473A/xx not_active IP Right Cessation
- 1992-07-15 PT PT100689A patent/PT100689B/pt not_active IP Right Cessation
- 1992-07-16 CN CN92105921A patent/CN1043759C/zh not_active Expired - Fee Related
- 1992-07-16 ZA ZA925306A patent/ZA925306B/xx unknown
- 1992-07-16 IE IE231192A patent/IE922311A1/en not_active Application Discontinuation
- 1992-07-16 NZ NZ243580A patent/NZ243580A/en unknown
- 1992-07-16 EG EG39792A patent/EG20048A/xx active
- 1992-07-16 MX MX9204190A patent/MX9204190A/es unknown
-
1994
- 1994-01-14 NO NO940144A patent/NO180445C/no not_active IP Right Cessation
- 1994-01-14 FI FI940192A patent/FI940192A0/fi unknown
- 1994-01-15 KR KR1019940700124A patent/KR0165003B1/ko not_active IP Right Cessation
-
1998
- 1998-09-11 FI FI981956A patent/FI981956A0/fi unknown
Also Published As
Publication number | Publication date |
---|---|
IL102473A0 (en) | 1993-01-14 |
NZ243580A (en) | 1994-10-26 |
JPH06504293A (ja) | 1994-05-19 |
BR9206272A (pt) | 1995-04-11 |
ZA925306B (en) | 1994-01-17 |
NO180445C (no) | 1997-04-23 |
KR0165003B1 (en) | 1999-01-15 |
MX9204190A (es) | 1993-01-01 |
CZ284133B6 (cs) | 1998-08-12 |
PT100689B (pt) | 1999-06-30 |
PL169884B1 (pl) | 1996-09-30 |
EP0594729A1 (en) | 1994-05-04 |
HUT70528A (en) | 1995-10-30 |
NO940144D0 (no) | 1994-01-14 |
NO180445B (no) | 1997-01-13 |
AU2322592A (en) | 1993-02-23 |
HU9400136D0 (en) | 1994-05-30 |
IE922311A1 (en) | 1993-01-27 |
FI981956A0 (fi) | 1998-09-11 |
JP2571904B2 (ja) | 1997-01-16 |
FI940192A (fi) | 1994-01-14 |
NO940144L (no) | 1994-01-14 |
FI940192A0 (fi) | 1994-01-14 |
WO1993002052A1 (en) | 1993-02-04 |
CN1043759C (zh) | 1999-06-23 |
EG20048A (en) | 1997-03-27 |
PT100689A (pt) | 1993-10-29 |
IL102473A (en) | 1997-07-13 |
TW201732B (fi) | 1993-03-11 |
CZ400892A3 (en) | 1994-03-16 |
AU655840B2 (en) | 1995-01-12 |
RU2065859C1 (ru) | 1996-08-27 |
CA2113568A1 (en) | 1993-02-04 |
CN1068566A (zh) | 1993-02-03 |
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