HUT68957A - Azanorbornane derivatives and pharmaceutical compositions comprising them as effective substance - Google Patents

Azanorbornane derivatives and pharmaceutical compositions comprising them as effective substance Download PDF

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Publication number
HUT68957A
HUT68957A HU9303666A HU9303666A HUT68957A HU T68957 A HUT68957 A HU T68957A HU 9303666 A HU9303666 A HU 9303666A HU 9303666 A HU9303666 A HU 9303666A HU T68957 A HUT68957 A HU T68957A
Authority
HU
Hungary
Prior art keywords
alkyl
phenyl
amino
diphenylmethyl
pyrrolidine
Prior art date
Application number
HU9303666A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9303666D0 (en
Inventor
Brian Thomas O'nell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU9303666D0 publication Critical patent/HU9303666D0/hu
Publication of HUT68957A publication Critical patent/HUT68957A/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fertilizers (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Luminescent Compositions (AREA)
  • Ink Jet (AREA)
HU9303666A 1991-06-21 1992-06-11 Azanorbornane derivatives and pharmaceutical compositions comprising them as effective substance HUT68957A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71988491A 1991-06-21 1991-06-21

Publications (2)

Publication Number Publication Date
HU9303666D0 HU9303666D0 (en) 1994-04-28
HUT68957A true HUT68957A (en) 1995-08-28

Family

ID=24891766

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9303666A HUT68957A (en) 1991-06-21 1992-06-11 Azanorbornane derivatives and pharmaceutical compositions comprising them as effective substance

Country Status (18)

Country Link
US (1) US5604252A (enExample)
EP (1) EP0591333B1 (enExample)
KR (1) KR940701384A (enExample)
AT (1) ATE149497T1 (enExample)
AU (1) AU2188992A (enExample)
CA (1) CA2111335A1 (enExample)
DE (1) DE69217945T2 (enExample)
DK (1) DK0591333T3 (enExample)
FI (1) FI935726A0 (enExample)
HU (1) HUT68957A (enExample)
IE (1) IE921987A1 (enExample)
IL (1) IL102208A0 (enExample)
MX (1) MX9203053A (enExample)
NO (1) NO934727L (enExample)
PT (1) PT100607A (enExample)
TW (1) TW202432B (enExample)
WO (1) WO1993000330A2 (enExample)
ZA (1) ZA924527B (enExample)

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FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
US5340826A (en) * 1993-02-04 1994-08-23 Pfizer Inc. Pharmaceutical agents for treatment of urinary incontinence
US5635510A (en) * 1993-05-06 1997-06-03 Merrell Pharmaceuticals Inc. Substituted pyrrolidin-3-yl-alkyl-piperidines
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
EP0653208A3 (en) * 1993-11-17 1995-10-11 Pfizer Substance P antagonists for the treatment or prevention of sunburn.
EP0659409A3 (en) * 1993-11-23 1995-08-09 Pfizer Substance P antagonists to inhibit angiogenesis.
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CN1067385C (zh) 1994-08-25 2001-06-20 默里尔药物公司 用于治疗变应性疾病的新的取代的哌啶类化合物
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
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TW458774B (en) 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
US6211199B1 (en) 1995-11-17 2001-04-03 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
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US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
CA2324116A1 (en) * 1999-10-25 2001-04-25 Susan Beth Sobolov-Jaynes Nk-1 receptor antagonists and eletriptan for the treatment of migraine
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Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
GB8823605D0 (en) * 1988-10-07 1988-11-16 Merck Sharp & Dohme Therapeutic agents
MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas
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JPH072740B2 (ja) * 1990-06-01 1995-01-18 フアイザー・インコーポレイテツド ３―アミノ―２―アリールキヌクリジン
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Also Published As

Publication number Publication date
TW202432B (enExample) 1993-03-21
DE69217945T2 (de) 1997-06-12
US5604252A (en) 1997-02-18
WO1993000330A3 (en) 1993-03-04
IL102208A0 (en) 1993-01-14
KR940701384A (ko) 1994-05-28
EP0591333A1 (en) 1994-04-13
EP0591333B1 (en) 1997-03-05
ZA924527B (en) 1993-12-20
NO934727D0 (no) 1993-12-20
DE69217945D1 (de) 1997-04-10
CA2111335A1 (en) 1993-01-07
FI935726L (fi) 1993-12-20
ATE149497T1 (de) 1997-03-15
FI935726A7 (fi) 1993-12-20
AU2188992A (en) 1993-01-25
HU9303666D0 (en) 1994-04-28
MX9203053A (es) 1992-12-01
NO934727L (no) 1993-12-20
PT100607A (pt) 1993-08-31
WO1993000330A2 (en) 1993-01-07
DK0591333T3 (da) 1997-05-20
IE921987A1 (en) 1992-12-30
FI935726A0 (fi) 1993-12-20

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