HUT67026A - 1h-imidazo [4,5-c] quinolin-4-amines pharmaceutical compositions containing the same and process for preparing thereof - Google Patents

1h-imidazo [4,5-c] quinolin-4-amines pharmaceutical compositions containing the same and process for preparing thereof

Info

Publication number
HUT67026A
HUT67026A HU9302457A HU9302457A HUT67026A HU T67026 A HUT67026 A HU T67026A HU 9302457 A HU9302457 A HU 9302457A HU 9302457 A HU9302457 A HU 9302457A HU T67026 A HUT67026 A HU T67026A
Authority
HU
Hungary
Prior art keywords
quinolin
imidazo
amines
preparing
same
Prior art date
Application number
HU9302457A
Other languages
English (en)
Other versions
HU222111B1 (hu
HU9302457D0 (en
Inventor
John F Gerster
Stephen L Crooks
Kyle J Lindstrom
Original Assignee
Minnesota Mining & Mfg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining & Mfg filed Critical Minnesota Mining & Mfg
Priority to HU9701087A priority Critical patent/HU9701087D0/hu
Priority to HU9701082A priority patent/HU220667B1/hu
Publication of HU9302457D0 publication Critical patent/HU9302457D0/hu
Publication of HUT67026A publication Critical patent/HUT67026A/hu
Publication of HU222111B1 publication Critical patent/HU222111B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Lubricants (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
HU9302457A 1991-03-01 1992-02-20 1H-imidazo[4,5-c]kinolin-származékok, ilyen vegyületeket tartalmazó gyógyászati készítmények és eljárás ezek előállítására HU222111B1 (hu)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU9701087A HU9701087D0 (en) 1991-03-01 1992-02-20 1-substituted 1h-imidazo[4,5-c]quinolin derivatives for producing 1-and 2-substituted 1h-imidazo[4,5-c]quinoline-4-amine derivatives
HU9701082A HU220667B1 (hu) 1991-03-01 1992-02-20 1- és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-amin-származékok előállításában alkalmazható kinolinszármazékok

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66292691A 1991-03-01 1991-03-01
US68732691A 1991-04-18 1991-04-18
PCT/US1992/001305 WO1992015582A1 (en) 1991-03-01 1992-02-20 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES

Publications (3)

Publication Number Publication Date
HU9302457D0 HU9302457D0 (en) 1993-11-29
HUT67026A true HUT67026A (en) 1995-01-30
HU222111B1 HU222111B1 (hu) 2003-04-28

Family

ID=27098631

Family Applications (5)

Application Number Title Priority Date Filing Date
HU9302457A HU222111B1 (hu) 1991-03-01 1992-02-20 1H-imidazo[4,5-c]kinolin-származékok, ilyen vegyületeket tartalmazó gyógyászati készítmények és eljárás ezek előállítására
HU9701084A HU222251B1 (hu) 1991-03-01 1992-02-20 1-és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-amin-származékok előállításában alkalmazható 1- és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-(szubsztituált)-származékok
HU9701083A HU222247B1 (hu) 1991-03-01 1992-02-20 1- és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-amin-származékok előállításában alkalmazható 1H-imidazo[4,5-c]kinolin-5N-oxid-származékok
HU9701089A HU222250B1 (hu) 1991-03-01 1992-02-20 1- és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-amin-származékok előállításában alkalmazható intermedierek
HU95P/P00753P HU211242A9 (en) 1991-03-01 1995-07-03 1-substituted, 2-substituted 1h-imidazo [4,5-c] quinolin-4-amines

Family Applications After (4)

Application Number Title Priority Date Filing Date
HU9701084A HU222251B1 (hu) 1991-03-01 1992-02-20 1-és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-amin-származékok előállításában alkalmazható 1- és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-(szubsztituált)-származékok
HU9701083A HU222247B1 (hu) 1991-03-01 1992-02-20 1- és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-amin-származékok előállításában alkalmazható 1H-imidazo[4,5-c]kinolin-5N-oxid-származékok
HU9701089A HU222250B1 (hu) 1991-03-01 1992-02-20 1- és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-amin-származékok előállításában alkalmazható intermedierek
HU95P/P00753P HU211242A9 (en) 1991-03-01 1995-07-03 1-substituted, 2-substituted 1h-imidazo [4,5-c] quinolin-4-amines

Country Status (18)

Country Link
EP (2) EP0582581B1 (hu)
JP (1) JP2955019B2 (hu)
AT (2) ATE179711T1 (hu)
AU (2) AU658621B2 (hu)
CA (2) CA2104782C (hu)
CZ (1) CZ285050B6 (hu)
DE (2) DE69229114T2 (hu)
DK (2) DK0582581T3 (hu)
ES (2) ES2186034T3 (hu)
HU (5) HU222111B1 (hu)
IE (1) IE920605A1 (hu)
IL (2) IL101110A (hu)
NO (1) NO303729B1 (hu)
NZ (1) NZ241784A (hu)
PH (1) PH31614A (hu)
SG (2) SG46492A1 (hu)
UA (1) UA32546C2 (hu)
WO (1) WO1992015582A1 (hu)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266575A (en) * 1991-11-06 1993-11-30 Minnesota Mining And Manufacturing Company 2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
US5395937A (en) * 1993-01-29 1995-03-07 Minnesota Mining And Manufacturing Company Process for preparing quinoline amines
JPH09500128A (ja) * 1993-07-15 1997-01-07 ミネソタ マイニング アンド マニュファクチャリング カンパニー イミダゾ〔４，５−ｃ〕ピリジン−４−アミン
US5648516A (en) * 1994-07-20 1997-07-15 Minnesota Mining And Manufacturing Company Fused cycloalkylimidazopyridines
US5352784A (en) * 1993-07-15 1994-10-04 Minnesota Mining And Manufacturing Company Fused cycloalkylimidazopyridines
US5482936A (en) * 1995-01-12 1996-01-09 Minnesota Mining And Manufacturing Company Imidazo[4,5-C]quinoline amines
US6133547A (en) * 1996-09-05 2000-10-17 Medtronic, Inc. Distributed activator for a two-dimensional shape memory alloy
US5939090A (en) * 1996-12-03 1999-08-17 3M Innovative Properties Company Gel formulations for topical drug delivery
JPH10298181A (ja) * 1997-04-25 1998-11-10 Sumitomo Pharmaceut Co Ltd タイプ２ヘルパーｔ細胞選択的免疫応答抑制剤
UA74852C2 (en) * 2000-12-08 2006-02-15 3M Innovative Properties Co Urea-substituted imidazoquinoline ethers
EP1541572A1 (en) * 2000-12-08 2005-06-15 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6664264B2 (en) * 2000-12-08 2003-12-16 3M Innovative Properties Company Thioether substituted imidazoquinolines
GB0211649D0 (en) * 2002-05-21 2002-07-03 Novartis Ag Organic compounds
WO2004009593A1 (en) * 2002-07-23 2004-01-29 Biogal Gyogyszergyar Rt. Preparation of 1h-imidazo[4,5-c]quinolin-4-amines via1h-imidazo [4,5-c]quinolin-4-phthalimide intermediates
CA2540541C (en) 2003-10-03 2012-03-27 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
JP4891088B2 (ja) 2003-11-25 2012-03-07 スリーエム イノベイティブ プロパティズ カンパニー 置換されたイミダゾ環系および方法
JP5128940B2 (ja) * 2004-06-18 2013-01-23 スリーエム イノベイティブ プロパティズ カンパニー 置換イミダゾキノリン、イミダゾピリジン、およびイミダゾナフチリジン
US8080560B2 (en) 2004-12-17 2011-12-20 3M Innovative Properties Company Immune response modifier formulations containing oleic acid and methods
CA2597092A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
HUE027400T2 (hu) 2005-02-18 2016-10-28 Glaxosmithkline Biologicals Sa Fehérjék és nukleinsavak agyhártyagyulladással/szepszissel kapcsolt Escherichia coliból
ES2385045T3 (es) 2005-02-18 2012-07-17 Novartis Vaccines And Diagnostics, Inc. Inmunógenos de Escherichia coli uropatogénica
EP1851224A2 (en) 2005-02-23 2007-11-07 3M Innovative Properties Company Hydroxyalkyl substituted imidazoquinolines
JP2008538203A (ja) 2005-02-23 2008-10-16 コーリー ファーマシューティカル グループ，インコーポレイテッド インターフェロンの生合成を優先的に誘導する方法
AU2006216798A1 (en) 2005-02-23 2006-08-31 Coley Pharmaceutical Group, Inc. Hydroxyalkyl substituted imidazoquinoline compounds and methods
CA2602590A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
NZ567978A (en) 2005-11-04 2011-09-30 Novartis Vaccines & Diagnostic Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant
CA2628152C (en) 2005-11-04 2016-02-02 Novartis Vaccines And Diagnostics S.R.L. Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture
EP1951299B1 (en) 2005-11-04 2012-01-04 Novartis Vaccines and Diagnostics S.r.l. Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
AU2006310337B9 (en) 2005-11-04 2013-11-28 Novartis Ag Adjuvanted influenza vaccines including cytokine-inducing agents
JP5247458B2 (ja) * 2005-11-04 2013-07-24 スリーエム・イノベイティブ・プロパティーズ・カンパニー ヒドロキシ及びアルコキシ置換１ｈ−イミダゾキノリン及び方法
PL1976559T6 (pl) 2006-01-27 2020-08-10 Novartis Influenza Vaccines Marburg Gmbh Szczepionki przeciw grypie zawierające hemaglutyninę i białka macierzy
JP2009534303A (ja) 2006-03-24 2009-09-24 ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー 冷蔵しないインフルエンザワクチンの保存
US20100285062A1 (en) 2006-03-31 2010-11-11 Novartis Ag Combined mucosal and parenteral immunization against hiv
US20110206692A1 (en) 2006-06-09 2011-08-25 Novartis Ag Conformers of bacterial adhesins
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
WO2008016475A2 (en) 2006-07-31 2008-02-07 3M Innovative Properties Company Immune response modifier compositions and methods
EP2586790A3 (en) 2006-08-16 2013-08-14 Novartis AG Immunogens from uropathogenic Escherichia coli
CA2663196A1 (en) 2006-09-11 2008-03-20 Novartis Ag Making influenza virus vaccines without using eggs
JP2011506264A (ja) 2006-12-06 2011-03-03 ノバルティス アーゲー インフルエンザウイルスの４つの株に由来する抗原を含むワクチン
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
BRPI0811125A2 (pt) * 2007-05-08 2017-05-09 Astrazeneca Ab imidazoquinolinas com propriedades imunomoduladoras
SI2185191T1 (sl) 2007-06-27 2012-12-31 Novartis Ag Cepiva proti influenci z majhnimi dodatki
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
WO2009111337A1 (en) * 2008-03-03 2009-09-11 Irm Llc Compounds and compositions as tlr activity modulators
EP2268309B1 (en) 2008-03-18 2015-01-21 Novartis AG Improvements in preparation of influenza virus vaccine antigens
PT2276486E (pt) * 2008-03-24 2013-12-04 4Sc Discovery Gmbh Novas imidazoquinolinas substituídas
US8568732B2 (en) 2009-03-06 2013-10-29 Novartis Ag Chlamydia antigens
SG175092A1 (en) 2009-04-14 2011-11-28 Novartis Ag Compositions for immunising against staphylococcus aerus
EP2424565A1 (en) 2009-04-27 2012-03-07 Novartis AG Adjuvanted vaccines for protecting against influenza
SG177533A1 (en) 2009-07-07 2012-02-28 Novartis Ag Conserved escherichia coli immunogens
HRP20220756T1 (hr) 2009-07-15 2022-09-02 Glaxosmithkline Biologicals S.A. Proteinski pripravci rsv f i postupci za izradu istih
SG178035A1 (en) 2009-07-16 2012-03-29 Novartis Ag Detoxified escherichia coli immunogens
GB0918392D0 (en) 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
GB0919690D0 (en) 2009-11-10 2009-12-23 Guy S And St Thomas S Nhs Foun compositions for immunising against staphylococcus aureus
WO2011084726A1 (en) * 2009-12-21 2011-07-14 3M Innovative Properties Company BIS [4-AMINO-2-(ETHOXYMETHYL)-1-(2-HYDROXY-2-METHYLPROPYL)-1H-IMIDAZO[4,5-c]QUINOLIN-5-IUM] 4-[(3-CARBOXYLATO-2-HYDROXYNAPHTHALEN-1-YL)METHYL]-3-HYDROXYNAPHTHALENE-2-CARBOXYLATE COMPOSITIONS AND METHODS
WO2011084725A1 (en) * 2009-12-21 2011-07-14 3M Innovative Properties Company 4-AMINO-2-(ETHOXYMETHYL)-1-(2-HYDROXY-2-METHYLPROPYL)-1H-IMIDAZO[4,5-c]QUINOLIN-5-IUM 1-HYDROXYNAPHTHALENE-2-CARBOXYLATE COMPOSITIONS AND METHODS
EP2519265B1 (en) 2009-12-30 2018-11-14 GlaxoSmithKline Biologicals SA Polysaccharide immunogens conjugated to e. coli carrier proteins
US20110293701A1 (en) 2010-05-26 2011-12-01 Selecta Biosciences, Inc. Multivalent synthetic nanocarrier vaccines
PL2575872T3 (pl) 2010-06-01 2021-02-22 Seqirus UK Limited Zatężanie antygenów szczepionkowych grypy bez liofilizacji
BR112012030616A2 (pt) 2010-06-01 2017-03-01 Novartis Ag concentração de antígenos de vacina com liofilização.
GB201009861D0 (en) 2010-06-11 2010-07-21 Novartis Ag OMV vaccines
WO2012023044A1 (en) 2010-08-20 2012-02-23 Novartis Ag Soluble needle arrays for delivery of influenza vaccines
WO2012061717A1 (en) 2010-11-05 2012-05-10 Selecta Biosciences, Inc. Modified nicotinic compounds and related methods
TR201908715T4 (tr) 2011-01-26 2019-07-22 Glaxosmithkline Biologicals Sa Rsv immünizasyon rejimi.
PL2707385T3 (pl) 2011-05-13 2018-03-30 Glaxosmithkline Biologicals Sa Prefuzyjne antygeny RSV F
US8728486B2 (en) 2011-05-18 2014-05-20 University Of Kansas Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds
WO2013009564A1 (en) 2011-07-08 2013-01-17 Novartis Ag Tyrosine ligation process
CA2854934A1 (en) 2011-11-07 2013-05-16 Novartis Ag Carrier molecule comprising a spr0096 and a spr2021 antigen
WO2013108272A2 (en) 2012-01-20 2013-07-25 International Centre For Genetic Engineering And Biotechnology Blood stage malaria vaccine
EA201590427A1 (ru) 2012-10-02 2015-09-30 Глаксосмитклайн Байолоджикалс С.А. Нелинейные сахаридные конъюгаты
US9987344B2 (en) 2012-11-30 2018-06-05 Glaxosmithkline Biologicals Sa Pseudomonas antigens and antigen combinations
CN104968200B (zh) * 2013-02-01 2018-03-06 维尔斯达医疗公司 具有抗炎、抗真菌、抗寄生物和抗癌活性的胺化合物
EP2870974A1 (en) 2013-11-08 2015-05-13 Novartis AG Salmonella conjugate vaccines
EA037818B1 (ru) 2014-03-26 2021-05-25 Глаксосмитклайн Байолоджикалс С.А. Мутантные стафилококковые антигены
PT3134402T (pt) 2014-04-22 2020-07-02 Hoffmann La Roche Compostos de 4-amino-imidazoquinolina
MY191185A (en) 2015-03-06 2022-06-04 Hoffmann La Roche Benzazepine dicarboxamide compounds
CN108137586B (zh) * 2015-09-14 2021-04-13 辉瑞大药厂 作为LRRK2抑制剂的新颖咪唑并[4,5-c]喹啉和咪唑并[4,5-c][1,5]萘啶衍生物
CN108055842B (zh) 2015-09-17 2021-06-29 豪夫迈·罗氏有限公司 亚磺酰基苯基或磺亚胺酰基苯基苯并氮杂䓬
JP7022702B2 (ja) 2016-05-23 2022-02-18 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト 第二級アミド基を有するベンズアゼピンジカルボキサミド化合物
JP6918838B2 (ja) 2016-05-23 2021-08-11 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 第三級アミド基を有するベンズアゼピンジカルボキサミド化合物
WO2017216054A1 (en) 2016-06-12 2017-12-21 F. Hoffmann-La Roche Ag Dihydropyrimidinyl benzazepine carboxamide compounds
TWI674261B (zh) * 2017-02-17 2019-10-11 美商英能腫瘤免疫股份有限公司 Nlrp3 調節劑
BR112019024177A2 (pt) * 2017-05-19 2020-06-02 Superb Wisdom Limited Derivados de resiquimode
JP7080501B2 (ja) * 2017-06-23 2022-06-06 バーディー バイオファーマシューティカルズ インコーポレイテッド 医薬品組成物
WO2020255038A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and pyridopyrimidine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL73534A (en) * 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
CA1271477A (en) * 1983-11-18 1990-07-10 John F. Gerster 1h-imidazo[4,5-c]quinolin-4-amines
EP0385630B1 (en) * 1989-02-27 1996-11-27 Riker Laboratories, Inc. 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals

Also Published As

Publication number Publication date
AU1566992A (en) 1992-10-06
SG70625A1 (en) 2000-02-22
CA2104782C (en) 2001-08-07
CZ285050B6 (cs) 1999-05-12
IE920605A1 (en) 1992-09-09
HU222111B1 (hu) 2003-04-28
CA2104782A1 (en) 1992-09-02
HU222250B1 (hu) 2003-05-28
DK0872478T3 (da) 2003-03-31
DK0582581T3 (da) 1999-11-08
CZ178893A3 (en) 1995-10-18
CA2289219C (en) 2003-05-20
ES2186034T3 (es) 2003-05-01
NO933069D0 (no) 1993-08-27
NO303729B1 (no) 1998-08-24
DE69229114D1 (de) 1999-06-10
AU658621B2 (en) 1995-04-27
ATE229943T1 (de) 2003-01-15
DE69232878D1 (de) 2003-01-30
HU211242A9 (en) 1995-11-28
EP0872478A3 (en) 1998-11-04
NZ241784A (en) 1995-06-27
ATE179711T1 (de) 1999-05-15
EP0872478B1 (en) 2002-12-18
IL101110A (en) 1995-12-08
IL114570A0 (en) 1995-11-27
SG46492A1 (en) 1998-02-20
ES2131070T3 (es) 1999-07-16
EP0582581B1 (en) 1999-05-06
NO933069L (no) 1993-11-01
IL114570A (en) 1996-10-31
IL101110A0 (en) 1992-11-15
IE990988A1 (en) 2000-12-13
EP0582581A1 (en) 1994-02-16
HU222247B1 (hu) 2003-05-28
JP2955019B2 (ja) 1999-10-04
HU9701084D0 (en) 1997-08-28
DE69232878T2 (de) 2003-11-20
WO1992015582A1 (en) 1992-09-17
JPH06504789A (ja) 1994-06-02
HU222251B1 (hu) 2003-05-28
CA2289219A1 (en) 1992-09-02
AU2715795A (en) 1995-09-21
AU673309B2 (en) 1996-10-31
EP0872478A2 (en) 1998-10-21
PH31614A (en) 1999-01-12
UA32546C2 (uk) 2001-02-15
HU9701083D0 (en) 1997-08-28
DE69229114T2 (de) 1999-11-04
HU9701089D0 (en) 1997-08-28
HU9302457D0 (en) 1993-11-29

Similar Documents

Publication Publication Date Title
HUT67026A (en) 1h-imidazo [4,5-c] quinolin-4-amines pharmaceutical compositions containing the same and process for preparing thereof
CA2107014A1 (en) Therapeutic Agent for Parkinson's Disease
AU4118697A (en) Purine derivatives and their use as anti-coagulants
HU905970D0 (en) Process for producing pyrazol derivatives
HK1004483A1 (en) Heterobicyclic derivatives
NZ242243A (en) 2-substituted adenine triphosphate derivatives and pharmaceutical compositions
AU6947401A (en) Phenylpyridazine derivatives and drugs containing the same
MY141488A (en) Hydroximic acid derivatives, processes for their preparation, and compositions comprising them
HU9301875D0 (en) 4-imino-quinolines, pharmaceutical preparatives containing them and methods for producing said compounds and preparatives
DE69630799D1 (en) Pyrimidinderivate
IE890293L (en) Quinolone derivatives
NZ330832A (en) 5-heterocyclyl-alkyl-3-oxo-N-(heteroaryl or aryl)-pyrido[1,2-a]benzimidazole-4-carboxamide derivatives and medicaments
PL300276A1 (en) Novel derivatives of 3-oxadiazolyl-5,6,7,8-tetrahydro-1,6-naphtyridine, novel derivatives of 5,6,7,8-tetrahydro-1,6-naphtyridine and method of obtaining 1,6-naphtyridine derivatives
CA2239053A1 (en) Diphenyl pyridyl ethane derivatives as pde iv inhibitors
DE69218718D1 (de) Pharmazeutische Zusammensetzungen die Triazole Derivate enthalten zur rektalen Verabbrechung

Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20030203

MM4A Lapse of definitive patent protection due to non-payment of fees