HUT64480A - An improved vaccine of meningococcus-polysaccharide conjugate - Google Patents

An improved vaccine of meningococcus-polysaccharide conjugate

Info

Publication number
HUT64480A
HUT64480A HU9201966A HU196692A HUT64480A HU T64480 A HUT64480 A HU T64480A HU 9201966 A HU9201966 A HU 9201966A HU 196692 A HU196692 A HU 196692A HU T64480 A HUT64480 A HU T64480A
Authority
HU
Hungary
Prior art keywords
meningococcus
polysaccharide conjugate
improved vaccine
vaccine
improved
Prior art date
Application number
HU9201966A
Other languages
English (en)
Other versions
HU218146B (hu
Inventor
Harold J Jennings
Francis Michon
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of HUT64480A publication Critical patent/HUT64480A/hu
Publication of HU218146B publication Critical patent/HU218146B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1228—Enterobacterales (O), e.g. Citrobacter (G), Serratia (G), Proteus (G), Providencia (G), Morganella (G) or Yersinia (G)
    • C07K16/1232—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1217—Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HU9201966A 1989-12-14 1990-12-13 Továbbfejlesztett meningokokkusz-poliszacharid-konjugátum vakcina HU218146B (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44819589A 1989-12-14 1989-12-14
PCT/CA1990/000437 WO1991008772A1 (en) 1989-12-14 1990-12-13 Improved meningococcal polysaccharide conjugate vaccine

Publications (2)

Publication Number Publication Date
HUT64480A true HUT64480A (en) 1994-01-28
HU218146B HU218146B (hu) 2000-06-28

Family

ID=23779371

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9201966A HU218146B (hu) 1989-12-14 1990-12-13 Továbbfejlesztett meningokokkusz-poliszacharid-konjugátum vakcina
HU9201966A HU9201966D0 (en) 1989-12-14 1990-12-13 An improved vaccine of meningococcus-polysaccharide conjunction

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU9201966A HU9201966D0 (en) 1989-12-14 1990-12-13 An improved vaccine of meningococcus-polysaccharide conjunction

Country Status (30)

Country Link
US (3) US5576002A (hu)
EP (1) EP0504202B1 (hu)
JP (1) JP2637845B2 (hu)
KR (1) KR0158436B1 (hu)
CN (4) CN1049223C (hu)
AR (1) AR243934A1 (hu)
AT (1) ATE121947T1 (hu)
AU (1) AU641715B2 (hu)
BR (1) BR9007917A (hu)
CA (1) CA2071811C (hu)
CZ (1) CZ283530B6 (hu)
DE (1) DE69019164T2 (hu)
DK (1) DK0504202T3 (hu)
ES (1) ES2071288T3 (hu)
FI (2) FI104539B (hu)
HR (1) HRP920872A2 (hu)
HU (2) HU218146B (hu)
IE (1) IE68414B1 (hu)
IL (1) IL96676A (hu)
IN (1) IN171747B (hu)
NO (2) NO305275B1 (hu)
NZ (1) NZ236471A (hu)
PH (1) PH30305A (hu)
PL (2) PL166659B1 (hu)
RO (1) RO111416B1 (hu)
RU (1) RU2105568C1 (hu)
SI (1) SI20008B (hu)
WO (1) WO1991008772A1 (hu)
YU (1) YU24391A (hu)
ZA (1) ZA9010065B (hu)

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ATE121947T1 (de) * 1989-12-14 1995-05-15 Ca Nat Research Council Verbessertes meningokokkale polysaccharidkonjugatvakzin.
IL107103A (en) * 1992-09-24 2001-03-19 Brigham & Womens Hospital Multivalent vaccine based on conjugated molecule comprising a capsular polysaccharide linked to a protein and a method for the preparation thereof
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US6153406A (en) * 1993-07-23 2000-11-28 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type B
US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
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US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US6284884B1 (en) 1995-06-07 2001-09-04 North American Vaccine, Inc. Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
US5811102A (en) * 1995-06-07 1998-09-22 National Research Council Of Canada Modified meningococcal polysaccharide conjugate vaccines
NZ311000A (en) * 1995-06-07 1999-04-29 Smithkline Beecham Biolog Vaccine comprising a polysaccharide antigen-carrier protein conjugate and a free carrier protein
ZA97248B (en) * 1996-01-18 1997-07-18 Rohm & Haas Method for identifying and quantifying polymers utilizing immunoassay techniques
PT939647E (pt) 1996-08-27 2002-04-29 Chiron Corp Glicpconjugados do serogrupo b de neisseria meningitidis e metodos de utilizacao dos mesmos
US6048527A (en) * 1996-08-27 2000-04-11 Chiron Corporation Antibodies that define unique Meningococcal B epitopes and vaccine compositions
US6426074B1 (en) * 1997-03-19 2002-07-30 The Brigham And Women's Hospital Inc. Group B Streptococcus vaccine
JP2002506448A (ja) 1997-06-24 2002-02-26 カイロン コーポレイション 抗髄膜炎菌ワクチン組成物を使用して成体を免疫する方法
DK1007546T3 (da) 1997-08-27 2009-03-16 Novartis Vaccines & Diagnostic Molekylære mimetika af meningokok-B-epitoper
CA2316975C (en) 1997-12-23 2009-03-24 North American Vaccine, Inc. Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugate vaccines
CN1263510C (zh) * 1998-08-19 2006-07-12 巴克斯特健康护理股份有限公司 多糖－蛋白质缀合物或寡糖－蛋白质缀合物、其制备方法及其应用
PL346645A1 (en) * 1998-08-19 2002-02-25 North American Vaccine IMMUNOGENIC β-PROPIONAMIDO-LINKED POLYSACCHARIDE PROTEIN CONJUGATE USEFUL AS A VACCINE PRODUCED USING AN N-ACRYLOYLATED POLYSACCHARIDE
US6436653B1 (en) 1998-12-15 2002-08-20 Exiqon A/S Method for introduction of reporter groups into bacterial lipopolysaccharide-derived carbohydrates and the subsequent coupling of such derivatives onto solid surfaces
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
US6518037B2 (en) * 1999-11-12 2003-02-11 University Of Iowa Research Foundation Two-component system that controls bacterial membrane synthesis
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
GB0011108D0 (en) * 2000-05-08 2000-06-28 Microscience Ltd Virulence gene and protein and their use
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
CN1306956C (zh) * 2001-04-17 2007-03-28 希龙公司 诱导功能活性抗体的脑膜炎球菌b抗原表位的分子模拟物
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
GB0121591D0 (en) * 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
DK1777236T3 (en) * 2002-03-26 2017-02-27 Glaxosmithkline Biologicals Sa MODIFIED SUCCARIDES WHICH IMPROVED WATER STABILITY FOR USE AS A MEDICINE
CN1816350B (zh) * 2002-05-14 2010-11-10 莱顿大学 带有几丁聚糖佐剂和/或脑膜炎抗原的粘膜疫苗
RU2494758C2 (ru) * 2002-08-02 2013-10-10 ГлаксоСмитКлайн Байолоджикалз с.а. Нейссериальные вакцинные композиции, содержащие комбинацию антигенов
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US20040219160A1 (en) * 2003-03-31 2004-11-04 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
RU2333223C2 (ru) 2003-08-12 2008-09-10 Лайпоксен Текнолоджиз Лимитед Альдегидные производные сиаловой кислоты, способы их получения, конъюгаты альдегидных производных сиаловой кислоты и фармацевтическая композиция на их основе
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
BRPI0512413A (pt) * 2004-06-23 2008-03-04 Childrens Hosp & Res Ct Oak derivados de polissacarìdeo e usos na indução de uma resposta imune
GB0428394D0 (en) * 2004-12-24 2005-02-02 Chiron Srl Saccharide conjugate vaccines
LT2351578T (lt) 2005-06-27 2017-04-10 Glaxosmithkline Biologicals S.A. Vakcinų gavimo būdas
US8206726B2 (en) 2006-02-06 2012-06-26 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
GB0611914D0 (en) 2006-06-15 2006-07-26 Teti Giuseppe Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide
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Also Published As

Publication number Publication date
SI20008A (sl) 2000-02-29
ZA9010065B (en) 1992-02-26
DE69019164D1 (de) 1995-06-08
CN1100428A (zh) 1995-03-22
HRP920872A2 (en) 1997-06-30
AR243934A1 (es) 1993-09-30
CZ628490A3 (en) 1997-12-17
PL166659B1 (pl) 1995-06-30
NO973311D0 (no) 1997-07-17
SI20008B (en) 2001-02-28
US5683699A (en) 1997-11-04
NO922316D0 (no) 1992-06-12
US5902586A (en) 1999-05-11
WO1991008772A1 (en) 1991-06-27
JPH05505392A (ja) 1993-08-12
CN1100656A (zh) 1995-03-29
AU641715B2 (en) 1993-09-30
HU9201966D0 (en) 1992-10-28
NO305275B1 (no) 1999-05-03
BR9007917A (pt) 1992-10-20
CA2071811C (en) 2003-11-04
RO111416B1 (ro) 1996-10-31
PH30305A (en) 1997-02-20
CN1036504C (zh) 1997-11-26
ES2071288T3 (es) 1995-06-16
IL96676A0 (en) 1991-09-16
CA2071811A1 (en) 1991-06-15
NO973311L (no) 1992-08-14
ATE121947T1 (de) 1995-05-15
NZ236471A (en) 1992-10-28
CN1096516A (zh) 1994-12-21
IN171747B (hu) 1992-12-26
KR0158436B1 (ko) 1998-12-01
IL96676A (en) 1996-09-12
CZ283530B6 (cs) 1998-04-15
AU6898791A (en) 1991-07-18
PL166035B1 (pl) 1995-03-31
NO307835B1 (no) 2000-06-05
RU2105568C1 (ru) 1998-02-27
IE904513A1 (en) 1991-06-19
FI104539B (fi) 2000-02-29
EP0504202A1 (en) 1992-09-23
IE68414B1 (en) 1996-06-12
FI19991917A7 (fi) 1999-09-09
NO922316L (no) 1992-08-14
FI19991917L (fi) 1999-09-09
EP0504202B1 (en) 1995-05-03
DK0504202T3 (da) 1995-10-02
DE69019164T2 (de) 1995-09-07
CN1036522C (zh) 1997-11-26
HU218146B (hu) 2000-06-28
PL288271A1 (en) 1991-12-16
CN1049223C (zh) 2000-02-09
US5576002A (en) 1996-11-19
YU24391A (sh) 1995-12-04
CN1072506C (zh) 2001-10-10
FI922737A0 (fi) 1992-06-12
CN1055541A (zh) 1991-10-23
JP2637845B2 (ja) 1997-08-06

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