HUP9800540A2 - Eljárás 2,6-piridin-dikarbonsavészter-származékok előállítására - Google Patents
Eljárás 2,6-piridin-dikarbonsavészter-származékok előállításáraInfo
- Publication number
- HUP9800540A2 HUP9800540A2 HU9800540A HUP9800540A HUP9800540A2 HU P9800540 A2 HUP9800540 A2 HU P9800540A2 HU 9800540 A HU9800540 A HU 9800540A HU P9800540 A HUP9800540 A HU P9800540A HU P9800540 A2 HUP9800540 A2 HU P9800540A2
- Authority
- HU
- Hungary
- Prior art keywords
- general formula
- powder
- alkyl
- pipe
- group
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title 1
- 239000000843 powder Substances 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- -1 2,6-pyridine-dicarboxylic acid ester Chemical class 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 abstract 2
- WJJMNDUMQPNECX-UHFFFAOYSA-N Dipicolinic acid Natural products OC(=O)C1=CC=CC(C(O)=O)=N1 WJJMNDUMQPNECX-UHFFFAOYSA-N 0.000 abstract 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 125000004216 fluoromethyl group Chemical group [H]C([H])(F)* 0.000 abstract 2
- 239000004575 stone Substances 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- SXDBWCPKPHAZSM-UHFFFAOYSA-M bromate Inorganic materials [O-]Br(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-M 0.000 abstract 1
- SXDBWCPKPHAZSM-UHFFFAOYSA-N bromic acid Chemical compound OBr(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-N 0.000 abstract 1
- 229910002091 carbon monoxide Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000005265 dialkylamine group Chemical group 0.000 abstract 1
- 239000000428 dust Substances 0.000 abstract 1
- 239000003546 flue gas Substances 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2523/00—Constitutive chemical elements of heterogeneous catalysts
- B01J2523/80—Constitutive chemical elements of heterogeneous catalysts of Group VIII of the Periodic Table
- B01J2523/82—Metals of the platinum group
- B01J2523/824—Palladium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
A találmány tárgya új eljárás (I) általánős képletű 2,6-piridin-dikarbőnsavészter-származékők előállítására - az (I) általánősképletben R1 jelentése alkilcsőpőrt, ciklőalkilcsőpőrt, arilcsőpőrtvagy aralkilcsőpőrt, és R2 és R3 jelentése egymástól függetlenülhidrőgénatőm vagy klóratőm és R4 jelentése hidrőgénatőm, alkilcsőpőrt,alkőxicsőpőrt vagy flűőratőm. A találmány szerinti (II) általánősképletű halőgén-piridin-származékőt - a (II) általánős képletű X klór-vagy brómatőmőt jelent - szén-mőnőxiddal és egy (III) általánősképletű alkőhőllal bázis jelenlétében és (IV) általánős képletű bisz-difenilfőszfin palládiűmmal alkőtőtt kőmplexe - a (IV) általánősképletben Q jelentése alkándilcsőpőrt vagy 1,1'ferrőcéndiilcsőpőrt,amelynek ciklőpentadienilcsőpőrtjai adőtt esetben alkilcsőpőrttal vagyarilcsőpőrttal szűbsztitűáltak, míg R5, R6, R7 és R8 jelentéseegymástól függetlenül hidrőgénatőm, alkilcsőpőrt, alkőxicsőpőrt,mőnőflűőrmetil-, diflűőrmetil-, triflűőrmetilcsőpőrt, flűőratőm,arilcsőpőrt, arilőxicsőpőrt, cianő- vagy dialkilaminőcsőpőrt -jelenlétében reagáltatnak. A 2,6-piridin-dikarbőnsavak főntős közbensőtermékek példáűl gyűlladásgátló hatású vegyületek előállítására. ŕ
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH59597 | 1997-03-12 |
Publications (4)
Publication Number | Publication Date |
---|---|
HU9800540D0 HU9800540D0 (en) | 1998-05-28 |
HUP9800540A2 true HUP9800540A2 (hu) | 1998-12-28 |
HUP9800540A3 HUP9800540A3 (en) | 1999-03-01 |
HU225239B1 HU225239B1 (en) | 2006-08-28 |
Family
ID=4190634
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9800540A HU225239B1 (en) | 1997-03-12 | 1998-03-12 | Process for producing 2,6-pyridin-dicarbonacid ester derivatives |
Country Status (18)
Country | Link |
---|---|
US (1) | US6103906A (hu) |
EP (1) | EP0864565B1 (hu) |
JP (1) | JPH10251232A (hu) |
KR (1) | KR100600465B1 (hu) |
CN (1) | CN1158262C (hu) |
AT (1) | ATE218550T1 (hu) |
CA (1) | CA2231800C (hu) |
CZ (1) | CZ291059B6 (hu) |
DE (1) | DE59804277D1 (hu) |
DK (1) | DK0864565T3 (hu) |
ES (1) | ES2174345T3 (hu) |
HU (1) | HU225239B1 (hu) |
NO (1) | NO308531B1 (hu) |
PL (1) | PL191438B1 (hu) |
PT (1) | PT864565E (hu) |
SI (1) | SI0864565T1 (hu) |
SK (1) | SK283433B6 (hu) |
TW (1) | TW400326B (hu) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001007415A1 (de) * | 1999-07-28 | 2001-02-01 | Lonza Ag | Verfahren zur herstellung von pyridazin-3,6-dicarbonsäureestern |
WO2001007416A1 (de) * | 1999-07-28 | 2001-02-01 | Lonza Ag | Verfahren zur herstellung von pyridazincarbonsäurederivaten |
WO2002034919A1 (en) * | 2000-10-27 | 2002-05-02 | Roche Diagnostics Gmbh | Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase |
US7547536B1 (en) | 2002-05-31 | 2009-06-16 | Jeol Usa, Inc. | Method for detecting bacterial spores |
CA2547600A1 (en) * | 2003-12-12 | 2005-06-30 | Syngenta Participations Ag | Novel herbicides |
JP4523834B2 (ja) * | 2004-11-26 | 2010-08-11 | ニチコン株式会社 | 電解コンデンサの駆動用電解液 |
CN103664767A (zh) * | 2013-12-06 | 2014-03-26 | 常熟市联创化学有限公司 | 一种2,6-吡啶二甲酸的制备方法 |
CN115838448B (zh) * | 2021-09-18 | 2024-01-09 | 中国科学技术大学 | 负载型催化剂及其制备方法和应用 |
CN113912533B (zh) * | 2021-11-23 | 2023-06-20 | 西安凯立新材料股份有限公司 | 一种制备3,6-二氯吡啶甲酸的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1620174B1 (de) * | 1965-11-19 | 1972-04-27 | Ruetgerswerke Ag | Verfahren zur oxidativen Herstellung von Pyridin-2,6-dicarbonsäure |
SU568462A1 (ru) * | 1974-12-03 | 1977-08-15 | Государственный Проектный Институт Строительного Машиностроения | Устройство дл нанесени лакокрасочного материала |
IT1089429B (it) * | 1977-12-01 | 1985-06-18 | Stoppani Luigi Spa | Procedimento in due stadi per preparare acido 2-6-piridin-bicarbossilico |
JPH0819009B2 (ja) * | 1987-03-12 | 1996-02-28 | 日本農薬株式会社 | カルボン酸アミド類の製造法 |
IL91083A (en) * | 1988-07-25 | 1993-04-04 | Ciba Geigy | Cyclohexanedione derivatives, their preparation and their use as herbicides |
TW371658B (en) * | 1992-03-06 | 1999-10-11 | Reilly Ind Inc | Process for producing 2-halo-nicotinic acid derivatives and precursor thereto |
JPH07126176A (ja) * | 1993-06-15 | 1995-05-16 | Hiroshi Sakurai | 活性酸素抑制剤 |
CA2209392C (en) * | 1996-07-23 | 2007-02-20 | Yves Bessard | Process for preparing pyridinecarboxylic esters |
-
1998
- 1998-02-25 CZ CZ1998545A patent/CZ291059B6/cs not_active IP Right Cessation
- 1998-03-09 SK SK313-98A patent/SK283433B6/sk not_active IP Right Cessation
- 1998-03-09 JP JP10057271A patent/JPH10251232A/ja active Pending
- 1998-03-10 ES ES98104312T patent/ES2174345T3/es not_active Expired - Lifetime
- 1998-03-10 PT PT98104312T patent/PT864565E/pt unknown
- 1998-03-10 DK DK98104312T patent/DK0864565T3/da active
- 1998-03-10 AT AT98104312T patent/ATE218550T1/de not_active IP Right Cessation
- 1998-03-10 EP EP98104312A patent/EP0864565B1/de not_active Expired - Lifetime
- 1998-03-10 DE DE59804277T patent/DE59804277D1/de not_active Expired - Fee Related
- 1998-03-10 SI SI9830102T patent/SI0864565T1/xx unknown
- 1998-03-10 TW TW087103452A patent/TW400326B/zh not_active IP Right Cessation
- 1998-03-11 NO NO981062A patent/NO308531B1/no not_active IP Right Cessation
- 1998-03-11 CA CA002231800A patent/CA2231800C/en not_active Expired - Fee Related
- 1998-03-12 CN CNB981055915A patent/CN1158262C/zh not_active Expired - Fee Related
- 1998-03-12 US US09/038,977 patent/US6103906A/en not_active Expired - Fee Related
- 1998-03-12 HU HU9800540A patent/HU225239B1/hu not_active IP Right Cessation
- 1998-03-12 PL PL325304A patent/PL191438B1/pl not_active IP Right Cessation
- 1998-03-12 KR KR1019980008296A patent/KR100600465B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE59804277D1 (de) | 2002-07-11 |
HU225239B1 (en) | 2006-08-28 |
CA2231800A1 (en) | 1998-09-12 |
JPH10251232A (ja) | 1998-09-22 |
HUP9800540A3 (en) | 1999-03-01 |
CA2231800C (en) | 2007-05-22 |
PL191438B1 (pl) | 2006-05-31 |
KR19980080185A (ko) | 1998-11-25 |
PL325304A1 (en) | 1998-09-14 |
SI0864565T1 (en) | 2002-08-31 |
CZ54598A3 (cs) | 1998-09-16 |
US6103906A (en) | 2000-08-15 |
ES2174345T3 (es) | 2002-11-01 |
NO308531B1 (no) | 2000-09-25 |
NO981062D0 (no) | 1998-03-11 |
DK0864565T3 (da) | 2002-09-16 |
ATE218550T1 (de) | 2002-06-15 |
TW400326B (en) | 2000-08-01 |
SK283433B6 (sk) | 2003-07-01 |
CN1193015A (zh) | 1998-09-16 |
PT864565E (pt) | 2002-10-31 |
CZ291059B6 (cs) | 2002-12-11 |
CN1158262C (zh) | 2004-07-21 |
HU9800540D0 (en) | 1998-05-28 |
SK31398A3 (en) | 1998-10-07 |
KR100600465B1 (ko) | 2007-03-02 |
NO981062L (no) | 1998-09-14 |
EP0864565A1 (de) | 1998-09-16 |
EP0864565B1 (de) | 2002-06-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |