ES2174345T3 - Procedimiento para la preparacion de esteres del acido 2,6 piridindicarboxilicos. - Google Patents

Procedimiento para la preparacion de esteres del acido 2,6 piridindicarboxilicos.

Info

Publication number
ES2174345T3
ES2174345T3 ES98104312T ES98104312T ES2174345T3 ES 2174345 T3 ES2174345 T3 ES 2174345T3 ES 98104312 T ES98104312 T ES 98104312T ES 98104312 T ES98104312 T ES 98104312T ES 2174345 T3 ES2174345 T3 ES 2174345T3
Authority
ES
Spain
Prior art keywords
acid
group
esters
preparation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98104312T
Other languages
English (en)
Inventor
Jean-Paul Dr Roduit
Yves Dr Bessard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Application granted granted Critical
Publication of ES2174345T3 publication Critical patent/ES2174345T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2523/00—Constitutive chemical elements of heterogeneous catalysts
    • B01J2523/80—Constitutive chemical elements of heterogeneous catalysts of Group VIII of the Periodic Table
    • B01J2523/82—Metals of the platinum group
    • B01J2523/824—Palladium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO PARA LA PREPARACION DE ESTERES DEL ACIDO 2,6 - PIRIDINDICARBOXILICO DE FORMULA GENERAL EN LA QUE R 1 ES UN GRUPO ALQUILO C 1 - C 6 , UN GRUPO CICLOALQUILO C 3 - C 6 , UN GRUPO ARILO O UN GRUPO ARILALQUILO Y R 2 Y R 3 SON INDEPENDIENTEMENTE HIDROGENO O CLORO Y R 4 ES HIDROGENO, UN GRUPO ALQUILO C 1 - C 6 , UN GRUPO ALCOXI C 1 - C 6 O FLUOR. LOS ESTERES DEL ACIDO 2,6 - PIRIDINDICARBOXILICO SE OBTIENEN MEDIANTE REACCION DE LAS CORRESPONDIENTES HALOPIRIDINAS, CON MONOXIDO DE CARBONO Y UN ALCOHOL DE FORMULA GENERAL EN LA QUE R SUP,1 TIENE EL SIGNIFICADO CITADO ANTERIORMENTE, EN PRESENCIA DE UNA BASE Y UN COMPLEJO DE PALADIO CON UNA BIS DIFENILFOSFINA. LOS ESTERES DEL ACIDO 2,6 - PIRIDINDICARBOXILICO SON PRODUCTOS INTERMEDIOS PARA LA PREPARACION DE COMPUESTOS CON ACCION ANTIINFLAMATORIA.
ES98104312T 1997-03-12 1998-03-10 Procedimiento para la preparacion de esteres del acido 2,6 piridindicarboxilicos. Expired - Lifetime ES2174345T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH59597 1997-03-12

Publications (1)

Publication Number Publication Date
ES2174345T3 true ES2174345T3 (es) 2002-11-01

Family

ID=4190634

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98104312T Expired - Lifetime ES2174345T3 (es) 1997-03-12 1998-03-10 Procedimiento para la preparacion de esteres del acido 2,6 piridindicarboxilicos.

Country Status (18)

Country Link
US (1) US6103906A (es)
EP (1) EP0864565B1 (es)
JP (1) JPH10251232A (es)
KR (1) KR100600465B1 (es)
CN (1) CN1158262C (es)
AT (1) ATE218550T1 (es)
CA (1) CA2231800C (es)
CZ (1) CZ291059B6 (es)
DE (1) DE59804277D1 (es)
DK (1) DK0864565T3 (es)
ES (1) ES2174345T3 (es)
HU (1) HU225239B1 (es)
NO (1) NO308531B1 (es)
PL (1) PL191438B1 (es)
PT (1) PT864565E (es)
SI (1) SI0864565T1 (es)
SK (1) SK283433B6 (es)
TW (1) TW400326B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007415A1 (de) * 1999-07-28 2001-02-01 Lonza Ag Verfahren zur herstellung von pyridazin-3,6-dicarbonsäureestern
WO2001007416A1 (de) * 1999-07-28 2001-02-01 Lonza Ag Verfahren zur herstellung von pyridazincarbonsäurederivaten
PL205561B1 (pl) * 2000-10-27 2010-05-31 Hoffmann La Roche Zmutowane białko zależnej od pirolochinolinochinonu rozpuszczalnej dehydrogenazy glukozowej, wyizolowany polinukleotyd kodujący to białko, wektor ekspresyjny, komórka gospodarza, sposób wytwarzania wariantów s-GDH, sposób wykrywania, oznaczania lub pomiaru glukozy i urządzenie do wykrywania lub pomiaru glukozy
US7547536B1 (en) 2002-05-31 2009-06-16 Jeol Usa, Inc. Method for detecting bacterial spores
EP1692108A1 (en) * 2003-12-12 2006-08-23 Syngenta Participations AG Novel herbicides
JP4523834B2 (ja) * 2004-11-26 2010-08-11 ニチコン株式会社 電解コンデンサの駆動用電解液
CN103664767A (zh) * 2013-12-06 2014-03-26 常熟市联创化学有限公司 一种2,6-吡啶二甲酸的制备方法
CN115838448B (zh) * 2021-09-18 2024-01-09 中国科学技术大学 负载型催化剂及其制备方法和应用
CN113912533B (zh) * 2021-11-23 2023-06-20 西安凯立新材料股份有限公司 一种制备3,6-二氯吡啶甲酸的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1620174B1 (de) * 1965-11-19 1972-04-27 Ruetgerswerke Ag Verfahren zur oxidativen Herstellung von Pyridin-2,6-dicarbonsäure
SU568462A1 (ru) * 1974-12-03 1977-08-15 Государственный Проектный Институт Строительного Машиностроения Устройство дл нанесени лакокрасочного материала
IT1089429B (it) * 1977-12-01 1985-06-18 Stoppani Luigi Spa Procedimento in due stadi per preparare acido 2-6-piridin-bicarbossilico
JPH0819009B2 (ja) * 1987-03-12 1996-02-28 日本農薬株式会社 カルボン酸アミド類の製造法
IL91083A (en) * 1988-07-25 1993-04-04 Ciba Geigy Cyclohexanedione derivatives, their preparation and their use as herbicides
TW371658B (en) * 1992-03-06 1999-10-11 Reilly Ind Inc Process for producing 2-halo-nicotinic acid derivatives and precursor thereto
JPH07126176A (ja) * 1993-06-15 1995-05-16 Hiroshi Sakurai 活性酸素抑制剤
CA2209392C (en) * 1996-07-23 2007-02-20 Yves Bessard Process for preparing pyridinecarboxylic esters

Also Published As

Publication number Publication date
SK283433B6 (sk) 2003-07-01
EP0864565A1 (de) 1998-09-16
NO981062D0 (no) 1998-03-11
CA2231800C (en) 2007-05-22
HU9800540D0 (en) 1998-05-28
NO308531B1 (no) 2000-09-25
ATE218550T1 (de) 2002-06-15
HU225239B1 (en) 2006-08-28
NO981062L (no) 1998-09-14
CZ291059B6 (cs) 2002-12-11
PL191438B1 (pl) 2006-05-31
PL325304A1 (en) 1998-09-14
TW400326B (en) 2000-08-01
CN1158262C (zh) 2004-07-21
KR100600465B1 (ko) 2007-03-02
JPH10251232A (ja) 1998-09-22
CN1193015A (zh) 1998-09-16
SK31398A3 (en) 1998-10-07
KR19980080185A (ko) 1998-11-25
EP0864565B1 (de) 2002-06-05
CZ54598A3 (cs) 1998-09-16
DK0864565T3 (da) 2002-09-16
CA2231800A1 (en) 1998-09-12
DE59804277D1 (de) 2002-07-11
HUP9800540A2 (hu) 1998-12-28
HUP9800540A3 (en) 1999-03-01
SI0864565T1 (en) 2002-08-31
PT864565E (pt) 2002-10-31
US6103906A (en) 2000-08-15

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