HUP0500459A2 - Streptococcus suis vakcinák és diagnosztikai tesztek - Google Patents

Streptococcus suis vakcinák és diagnosztikai tesztek

Info

Publication number
HUP0500459A2
HUP0500459A2 HU0500459A HUP0500459A HUP0500459A2 HU P0500459 A2 HUP0500459 A2 HU P0500459A2 HU 0500459 A HU0500459 A HU 0500459A HU P0500459 A HUP0500459 A HU P0500459A HU P0500459 A2 HUP0500459 A2 HU P0500459A2
Authority
HU
Hungary
Prior art keywords
streptococcus
vaccines
streptococcus suis
nucleic acid
diagnostic tests
Prior art date
Application number
HU0500459A
Other languages
English (en)
Inventor
Hilda Elizabeth Smith
Original Assignee
ID-Lelystad, Instituut voor Dierhouderij en Diergendheid B.V. Á
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ID-Lelystad, Instituut voor Dierhouderij en Diergendheid B.V. Á filed Critical ID-Lelystad, Instituut voor Dierhouderij en Diergendheid B.V. Á
Publication of HUP0500459A2 publication Critical patent/HUP0500459A2/hu
Publication of HUP0500459A3 publication Critical patent/HUP0500459A3/hu
Publication of HU228700B1 publication Critical patent/HU228700B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A találmány tárgyát általánosságban sertések Streptococcus-fertőzéseivel szembeni vakcinák képezik, közelebbről pedig aStreptococcus suis baktériumtok-génklaszter és az abból származó génekés génfragmensek izolált rekombináns nukleinsav-szekvenciája. Atalálmány tárgyát képezik továbbá a találmány szerinti nukleinsavakbólszármazó nukleinsavpróbák és -láncindítók; a nukleinsav-próbákat és -láncindítókat tartalmazó diagnosztikai tesztek; valamint a találmányszerinti nukleinsavak által kódolt proteinek és fragmenseik. Atalálmány tárgyát képezik továbbá eljárások streptococcus suistokantigénjének előállítására; az antigént tartalmazó vakcinák;valamint rekombináns Streptococcus suis-mutánsok. A találmány szerintimegoldás alkalmas Streptococcus suis gyors detektálására és/vagyszerotipizálására, valamint szerotípus-specifikus Streptococcus-betegségek ellen védettséget nyújtó vakcinák és Streptococcus-fertőzések elleni multivalans vakcinák kifejlesztésére.
HU0500459A 1998-07-22 1999-07-19 Streptococcus suis vaccines and diagnostic tests HU228700B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98202465 1998-07-22
EP98202467 1998-07-22
PCT/NL1999/000460 WO2000005378A2 (en) 1998-07-22 1999-07-19 Streptococcus suis vaccines and diagnostic tests

Publications (3)

Publication Number Publication Date
HUP0500459A2 true HUP0500459A2 (hu) 2005-08-29
HUP0500459A3 HUP0500459A3 (en) 2010-08-30
HU228700B1 HU228700B1 (en) 2013-05-28

Family

ID=26150559

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0500459A HU228700B1 (en) 1998-07-22 1999-07-19 Streptococcus suis vaccines and diagnostic tests

Country Status (9)

Country Link
US (4) US7125548B2 (hu)
EP (1) EP1098980B1 (hu)
AU (1) AU5070999A (hu)
CA (1) CA2341268C (hu)
DK (1) DK1098980T3 (hu)
ES (1) ES2512496T3 (hu)
HU (1) HU228700B1 (hu)
PL (1) PL204863B1 (hu)
WO (1) WO2000005378A2 (hu)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL204863B1 (pl) 1998-07-22 2010-02-26 Stichting Dienst Landbouwkundi Zastosowanie mutanta Streptococcus, szczepionka i sposoby kontrolowania lub eliminowania choroby paciorkowcowej w populacji
US6949372B2 (en) 1999-03-02 2005-09-27 The Johns Hopkins University Engineering intracellular sialylation pathways
WO2000052136A2 (en) 1999-03-02 2000-09-08 Human Genome Sciences, Inc. Human glycosylation enzymes
NZ593617A (en) * 2000-10-27 2012-04-27 Novartis Vaccines & Diagnostic Nucleic acids and proteins from streptococcus groups A & B
EP1205552A1 (en) 2000-11-09 2002-05-15 ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. Virulence of streptococci, involving ORFs from Streptococcus suis
WO2002061070A2 (en) 2001-02-02 2002-08-08 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Environmentally regulated genes, involved in the virulence of streptococcus suis
AU2002342485A1 (en) * 2001-11-23 2003-06-10 Universite De Montreal Streptococcus suis avirulent vaccine and uses in antibiotic design
JP4261855B2 (ja) 2002-09-19 2009-04-30 キヤノン株式会社 フェナントロリン化合物及びそれを用いた有機発光素子
WO2007126885A2 (en) * 2006-03-28 2007-11-08 The Trustees Of The University Of Pennsylvania Live, attenuated pneumococcal vaccine
CN101020894B (zh) * 2007-01-17 2010-10-27 中国人民解放军南京军区军事医学研究所 一株无毒2型猪链球菌及其制备方法、应用
CA2683748C (en) 2007-04-13 2016-02-16 The Board Of Regents Of The University Of Oklahoma Mutants of cholesterol-dependent cytolysins and uses thereof
EP2023143A1 (en) * 2007-08-06 2009-02-11 Boehringer Ingelheim Vetmedica Gmbh Immunogenic streptococcus proteins
TW201043242A (en) 2009-03-26 2010-12-16 Intervet Int Bv Vaccine for protection against Streptococcus suis bacteria of various serotypes
GB201209014D0 (en) * 2012-05-22 2012-07-04 Moredun Res Inst Vaccine
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
WO2016081839A1 (en) 2014-11-21 2016-05-26 The Board Of Regents Of The University Of Oklahoma Pneumolysin mutants and methods of use thereof
US11155585B2 (en) 2015-07-09 2021-10-26 Intervacc Ab Vaccine against S. suis infection
CA3000201A1 (en) * 2015-10-07 2017-04-13 Boehringer Ingelheim Vetmedica, Inc. Streptococcus suis polysacchari de-protein conjugate composition
CN105274102A (zh) * 2015-11-12 2016-01-27 广东海大畜牧兽医研究院有限公司 辅助鉴定猪链球菌2型、猪链球菌7型和猪链球菌9型的引物组及其应用
AU2017357813A1 (en) * 2016-11-11 2019-06-27 Boehringer Ingelheim Vetmedica Gmbh Attenuating bacterial virulence by attenuating bacterial folate transport
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11103569B2 (en) 2017-12-15 2021-08-31 Intervet Inc. Vaccine for protection against Streptococcus suis
RU2020131305A (ru) * 2018-03-23 2022-04-26 Коранекс Кэпитал Прецизионные гликоконъюгаты в качестве терапевтических инструментов
EP3876980A1 (en) 2018-11-08 2021-09-15 Intervet International B.V. A vaccine for protection against streptococcus suis
CN112280880A (zh) * 2020-11-20 2021-01-29 中国疾病预防控制中心传染病预防控制所 用于液相芯片多重PCR鉴别猪链球菌17种新cps型的引物组合及其检测试剂盒
CN112694988B (zh) * 2020-12-15 2022-12-06 武汉市农业科学院 一种鸡源猪链球菌弱毒株及其应用
CN113832068B (zh) * 2021-10-14 2023-07-25 河南兴华生物技术有限公司 链球菌菌株及防治猪链球菌病的疫苗
AU2022395498A1 (en) * 2021-11-25 2024-05-23 Chr. Hansen A/S Polysaccharides resulting in improved water holding capacity of dairy products
WO2023203238A1 (en) 2022-04-22 2023-10-26 Intervacc Ab Streptococcus suis vaccine composition comprising immunogenic fusion polypeptides

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9100510A (nl) 1991-03-21 1992-10-16 Centraal Diergeneeskundig Inst Dna-sequenties die coderen voor kenmerken van virulentie van streptococcus suis en delen daarvan, daarvan afgeleide polypeptiden en antilichamen, alsmede toepassing daarvan bij de diagnose van en de bescherming tegen infectie met s. suis bij zoogdieren, waaronder de mens.
SE468630B (sv) 1991-05-31 1993-02-22 Sts Komeetstaal Holding Bv Spaar- och avstickningsskaer med fyra symmetriska skaerhoern
FR2688515B1 (fr) 1992-03-13 1995-03-31 Institut Rech Agronomique Plasmide thermosensible.
US5928900A (en) 1993-09-01 1999-07-27 The Rockefeller University Bacterial exported proteins and acellular vaccines based thereon
EP0804582A1 (en) 1994-05-16 1997-11-05 The Uab Research Foundation $i(STREPTOCOCCUS PNEUMONIAE) CAPSULAR POLYSACCHARIDE GENES AND FLANKING REGIONS
US5681570A (en) * 1995-01-12 1997-10-28 Connaught Laboratories Limited Immunogenic conjugate molecules
ATE256749T1 (de) 1995-01-23 2004-01-15 Novozymes As Dna-integration durch transposition
EP0750042A1 (fr) * 1995-06-20 1996-12-27 Societe Des Produits Nestle S.A. Bactéries lactiques produisant des exopolysaccharides
EP0750043B1 (fr) * 1995-06-20 2001-05-23 Societe Des Produits Nestle S.A. Bactéries lactiques produisant des exopolysaccharides
JP2001510989A (ja) 1996-11-01 2001-08-07 スミスクライン・ビーチャム・コーポレイション 新規コーディング配列
US6800744B1 (en) 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
PL204863B1 (pl) * 1998-07-22 2010-02-26 Stichting Dienst Landbouwkundi Zastosowanie mutanta Streptococcus, szczepionka i sposoby kontrolowania lub eliminowania choroby paciorkowcowej w populacji
WO2000006738A2 (en) 1998-07-27 2000-02-10 Microbial Technics Limited NUCLEIC ACIDS AND PROTEINS FROM $i(STREPTOCOCCUS PNEUMONIAE)
EP1140157B1 (en) 1998-12-21 2009-02-18 MedImmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
EP1205552A1 (en) * 2000-11-09 2002-05-15 ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. Virulence of streptococci, involving ORFs from Streptococcus suis
WO2002061070A2 (en) 2001-02-02 2002-08-08 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Environmentally regulated genes, involved in the virulence of streptococcus suis
EP2023143A1 (en) 2007-08-06 2009-02-11 Boehringer Ingelheim Vetmedica Gmbh Immunogenic streptococcus proteins

Also Published As

Publication number Publication date
EP1098980B1 (en) 2014-09-03
US20110171252A1 (en) 2011-07-14
USRE45170E1 (en) 2014-09-30
PL204863B1 (pl) 2010-02-26
HUP0500459A3 (en) 2010-08-30
HU228700B1 (en) 2013-05-28
US20070111236A1 (en) 2007-05-17
WO2000005378A2 (en) 2000-02-03
US7776323B2 (en) 2010-08-17
DK1098980T3 (da) 2014-09-29
CA2341268C (en) 2010-10-12
EP1098980A2 (en) 2001-05-16
US8728490B2 (en) 2014-05-20
US7125548B2 (en) 2006-10-24
US20020055168A1 (en) 2002-05-09
WO2000005378A3 (en) 2000-06-15
AU5070999A (en) 2000-02-14
PL346369A1 (en) 2002-02-11
ES2512496T3 (es) 2014-10-24
CA2341268A1 (en) 2000-02-03

Similar Documents

Publication Publication Date Title
HUP0500459A2 (hu) Streptococcus suis vakcinák és diagnosztikai tesztek
Davies et al. Characterisation of bovine strains of Pasteurella multocida and comparison with isolates of avian, ovine and porcine origin
HUP0105379A2 (hu) Lawsonia intracellularis elleni oltóanyag
BR0208944A (pt) quadros de leitura aberta de streptococus pneumoniae codificando os antìgenos de polipeptìdeos e seus usos
HUP0102304A1 (hu) B Csoportba tartozó Streptococcus antigének
CY1107702T1 (el) Πολυπεπτιδια, νουκλεϊκα οξεα στρεπτοκοκκου ομαδας β και θεραπευτικες συνθεσεις και εμβολια αυτων
NZ540544A (en) Nucleic acids and proteins from streptococcus groups A & B
BR0208874A (pt) Proteìnas superficiais de streptococcus pyogenes
Collins et al. Diagnosis and epidemiology of bovine tuberculosis using molecular biological approaches
DK524289A (da) Fremgangsmaade til diagnosticering for og vaccine mod mycobakterier
De et al. Purification and characterization of Streptococcus pneumoniae palmitoylated pneumococcal surface adhesin A expressed in Escherichia coli
Sałamaszyńska-Guz et al. Biofilm formation and motility are promoted by Cj0588-directed methylation of rRNA in Campylobacter jejuni
GB2233977A (en) Cysteine-free streptolysin O
Kowalczewska et al. Identification of candidate antigen in Whipple's disease using a serological proteomic approach
Mon et al. Evaluation of cocktails with recombinant proteins of Mycobacterium bovis for a specific diagnosis of bovine tuberculosis
HUP0100130A2 (hu) Rekombináns Mycoplasma hyopneumoniae vakcina
CA2428278A1 (en) Virulence of streptococci
ES2377569T3 (es) Polinucleótidos de Haemophilus parasuis y su uso
Anderson et al. Cloning, expression and sequence analysis of the Bartonella henselae gene encoding the HtrA stress-response protein
KR101343352B1 (ko) ｔｈｉＤ 유전자 발현 산물의 형광 영상화를 통한 바실러스 서브틸리스 검출 방법
Du et al. Diadenylate cyclase evaluation of ssDacA (SSU98_1483) in Streptococcus suis serotype 2
Smith et al. Gene encoding the group B streptococcal protein R4, its presence in clinical reference laboratory isolates & R4 protein pepsin sensitivity
AU2667600A (en) Identification of specific differentially expressed antigens
Chen et al. Application of proteomics in identifying crucial virulence factors shared by different Streptococcus iniae isolates for developing an effective subunit vaccine against S. iniae in tilapia
WO2003046183A3 (en) Streptococcus suis avirulent vaccine and uses in antibiotic design

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK, NL

Free format text: FORMER OWNER(S): ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V., NL

HC9A Change of name, address

Owner name: STICHTING WAGENINGEN RESEARCH, NL

Free format text: FORMER OWNER(S): ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V., NL; STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK, NL

MM4A Lapse of definitive patent protection due to non-payment of fees