HUP0302038A2 - Biguanidszármazékok alkalmazása hegesedést elżsegítż gyógyszerek elżállítására - Google Patents
Biguanidszármazékok alkalmazása hegesedést elżsegítż gyógyszerek elżállításáraInfo
- Publication number
- HUP0302038A2 HUP0302038A2 HU0302038A HUP0302038A HUP0302038A2 HU P0302038 A2 HUP0302038 A2 HU P0302038A2 HU 0302038 A HU0302038 A HU 0302038A HU P0302038 A HUP0302038 A HU P0302038A HU P0302038 A2 HUP0302038 A2 HU P0302038A2
- Authority
- HU
- Hungary
- Prior art keywords
- group
- making
- biguanide derivatives
- wound healing
- medicine
- Prior art date
Links
- 150000004283 biguanides Chemical class 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 230000029663 wound healing Effects 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005160 aryl oxy alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
A találmány tárgya (I) általános képletű biguanidszármazékokalkalmazása, a képletben R1 és R2 jelentése egymástól függetlenülhidrogénatom, 1-7 szénatomos alkil-, 3-7 szénatomos cikloalkil-csoport, heterociklusos csoport, 2-7 szénatomos alkenilcsoport,arilcsoport, aralkilcsoport, ahol az alkilrész 1-7 szénatomos,ariloxialkil-csoport, ahol az alkilrész 1-7 szénatomos, vagyheteroaril-csoport, vagy R1 és R2 együtt 2-7 szénatomosalkiléncsoportot alkot, amely egy vagy több heteroatomot istartalmazhat, és R3 jelentése primer vagy tercier vagy egy (a) képletűaminocsoport, vagy gyógyszerészetileg elfogadható sóik alkalmazásahegképző hatású gyógyszer előállítására, amely gyógyszer helyilegalkalmazandó gyógyszerészeti formában van. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0006798A FR2809310B1 (fr) | 2000-05-26 | 2000-05-26 | Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant |
PCT/FR2001/001598 WO2001091696A2 (fr) | 2000-05-26 | 2001-05-23 | Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0302038A2 true HUP0302038A2 (hu) | 2003-09-29 |
HUP0302038A3 HUP0302038A3 (en) | 2009-08-28 |
HU229205B1 HU229205B1 (en) | 2013-09-30 |
Family
ID=8850685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0302038A HU229205B1 (en) | 2000-05-26 | 2001-05-23 | Use of biguanide derivatives for preparation of medicament having a wound healing effect |
Country Status (25)
Country | Link |
---|---|
US (1) | US7199159B2 (hu) |
EP (1) | EP1283708B1 (hu) |
JP (1) | JP4987209B2 (hu) |
KR (1) | KR20030029050A (hu) |
CN (1) | CN100420439C (hu) |
AR (1) | AR032617A1 (hu) |
AT (1) | ATE300942T1 (hu) |
AU (2) | AU6401101A (hu) |
BG (1) | BG65847B1 (hu) |
BR (1) | BRPI0111142C1 (hu) |
CA (1) | CA2410025C (hu) |
DE (1) | DE60112431T2 (hu) |
DK (1) | DK1283708T3 (hu) |
EC (1) | ECSP024359A (hu) |
EE (1) | EE05393B1 (hu) |
ES (1) | ES2244625T3 (hu) |
FR (1) | FR2809310B1 (hu) |
HU (1) | HU229205B1 (hu) |
MX (1) | MXPA02011622A (hu) |
MY (1) | MY137468A (hu) |
NO (1) | NO20025635L (hu) |
PT (1) | PT1283708E (hu) |
SK (1) | SK287249B6 (hu) |
UA (1) | UA76415C2 (hu) |
WO (1) | WO2001091696A2 (hu) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2858232B1 (fr) * | 2003-07-29 | 2006-03-03 | Pierre Potier | Utilisation d'un derive de biguanide pour proteger la peau des radiations uvb |
DE102004022645A1 (de) * | 2004-05-07 | 2005-12-15 | Resorba Wundversorgung Gmbh & Co. Kg | Bioresorbierbares Material auf Kollagen-Basis |
JP4877456B2 (ja) * | 2005-04-14 | 2012-02-15 | 株式会社 メドレックス | ビグアナイド系薬剤を含有するゼリー製剤 |
CN105152983A (zh) * | 2007-01-29 | 2015-12-16 | 韩诺生物制药株式会社 | N,n-二甲基亚氨基二碳亚氨酸二酰胺乙酸盐、其制备方法和包含其的药物组合物 |
EP2321425A1 (en) * | 2008-08-28 | 2011-05-18 | Tyco Healthcare Group LP | Carrier neutralization/modification in antimicrobial compositions, articles and methods |
WO2011083998A2 (ko) | 2010-01-06 | 2011-07-14 | 한올바이오파마주식회사 | 바이구아나이드 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물 |
US10279007B2 (en) | 2010-11-15 | 2019-05-07 | Oxygenetix Institute, Inc. | Topical treatment method for healing wounds, disinfecting, covering and concealing the wound until healing occurs |
DE212011100215U1 (de) | 2011-07-22 | 2014-03-05 | Karel Paul Bouter | Ernährungsprodukt, umfassend ein Biguanid |
KR101425061B1 (ko) * | 2011-08-08 | 2014-08-06 | 한올바이오파마주식회사 | Ν1-고리아민-ν5-치환된 페닐 바이구아나이드 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물 |
WO2013022280A2 (en) * | 2011-08-08 | 2013-02-14 | Hanall Biopharma Co., Ltd. | N1-cyclic amine-n2-substituted biguanide derivatives, methods of preparing the same and pharmaceutical composition comprising the same |
KR101486865B1 (ko) | 2011-08-08 | 2015-01-30 | 한올바이오파마주식회사 | N1-고리아민-n5-치환된 바이구아나이드 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물 |
CN106458868A (zh) | 2014-04-17 | 2017-02-22 | 伊谬诺米特医疗有限公司 | 胍化合物及其用途 |
CN104262205B (zh) * | 2014-09-02 | 2017-04-12 | 浙江工业大学 | N‑芳基双胍氢碘酸盐类化合物及其制备方法和应用 |
KR102216701B1 (ko) | 2014-11-20 | 2021-02-18 | 이뮤노메트테라퓨틱스 인코포레이티드 | 바이구아나이드 화합물 및 이의 용도 |
FR3035787B1 (fr) | 2015-05-07 | 2018-08-24 | L'oreal | Procede de traitement des matieres keratiniques a partir de derives de c-glycosides amides, acides ou ester, et la composition cosmetique les contenant |
FR3053892A1 (fr) | 2016-07-12 | 2018-01-19 | Urgo Recherche Innovation Et Developpement | Pansement permettant la liberation controlee et prolongee de la metformine |
CN106822075A (zh) * | 2017-03-31 | 2017-06-13 | 浙江萧山医院 | 二甲双胍在促进伤口愈合中的应用 |
FR3068974B1 (fr) | 2017-07-12 | 2019-08-02 | Urgo Recherche Innovation Et Developpement | Pansement permettant la liberation controlee et prolongee d'actif |
FR3088542B1 (fr) | 2018-11-21 | 2021-03-19 | Waterdiam France Sas | Composition cicatrisante comprenant une eau électrolysée |
CN110179776B (zh) * | 2019-05-31 | 2022-09-06 | 宁夏医科大学 | 二甲双胍的新用途与二甲双胍组合物及组合物的制备方法和应用 |
CN112494469A (zh) * | 2020-07-30 | 2021-03-16 | 吴学雷 | 二甲双胍在制备预防和/或治疗瘢痕的药物中的应用 |
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US2961377A (en) | 1957-08-05 | 1960-11-22 | Us Vitamin Pharm Corp | Oral anti-diabetic compositions and methods |
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CN1197643A (zh) * | 1997-04-30 | 1998-11-04 | 谢瑞钢 | 一种创伤油膏 |
ATE261935T1 (de) * | 1997-12-08 | 2004-04-15 | Bristol Myers Squibb Co | Neue metformin salze und verfahren |
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BR9912395A (pt) * | 1998-07-24 | 2001-10-16 | Seo Hong Yoo | Preparação de formas de dosagem de solução clara aquosa com ácidos biliares |
WO2000033829A1 (de) | 1998-12-05 | 2000-06-15 | Fresenius Kabi Deutschland Gmbh | Verwendung von poly (hexamethylen) biguanid zur herstellung eines mittels zur förderung der heilung von infektionsfreien wunden |
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ATE266409T1 (de) * | 2000-04-13 | 2004-05-15 | Pfizer Prod Inc | Synergistische wirkung von glyburide und milrinone |
-
2000
- 2000-05-26 FR FR0006798A patent/FR2809310B1/fr not_active Expired - Lifetime
-
2001
- 2001-05-23 AU AU6401101A patent/AU6401101A/xx active Pending
- 2001-05-23 CN CNB018114032A patent/CN100420439C/zh not_active Expired - Lifetime
- 2001-05-23 US US10/297,003 patent/US7199159B2/en not_active Expired - Lifetime
- 2001-05-23 DK DK01938318T patent/DK1283708T3/da active
- 2001-05-23 CA CA2410025A patent/CA2410025C/fr not_active Expired - Lifetime
- 2001-05-23 EE EEP200200657A patent/EE05393B1/xx not_active IP Right Cessation
- 2001-05-23 HU HU0302038A patent/HU229205B1/hu not_active IP Right Cessation
- 2001-05-23 JP JP2001587712A patent/JP4987209B2/ja not_active Expired - Lifetime
- 2001-05-23 KR KR1020027016052A patent/KR20030029050A/ko not_active Application Discontinuation
- 2001-05-23 WO PCT/FR2001/001598 patent/WO2001091696A2/fr active IP Right Grant
- 2001-05-23 SK SK1658-2002A patent/SK287249B6/sk not_active IP Right Cessation
- 2001-05-23 ES ES01938318T patent/ES2244625T3/es not_active Expired - Lifetime
- 2001-05-23 EP EP01938318A patent/EP1283708B1/fr not_active Expired - Lifetime
- 2001-05-23 PT PT01938318T patent/PT1283708E/pt unknown
- 2001-05-23 DE DE60112431T patent/DE60112431T2/de not_active Expired - Lifetime
- 2001-05-23 AU AU2001264011A patent/AU2001264011B2/en not_active Expired
- 2001-05-23 AT AT01938318T patent/ATE300942T1/de active
- 2001-05-23 UA UA2002097477A patent/UA76415C2/uk unknown
- 2001-05-23 BR BRPI0111142A patent/BRPI0111142C1/pt not_active IP Right Cessation
- 2001-05-23 MX MXPA02011622A patent/MXPA02011622A/es active IP Right Grant
- 2001-05-24 AR ARP010102484A patent/AR032617A1/es unknown
- 2001-05-24 MY MYPI20012487A patent/MY137468A/en unknown
-
2002
- 2002-11-21 BG BG107304A patent/BG65847B1/bg unknown
- 2002-11-22 NO NO20025635A patent/NO20025635L/no not_active Application Discontinuation
- 2002-11-22 EC EC2002004359A patent/ECSP024359A/es unknown
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