IT1256111B - Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica - Google Patents
Sali dell'acido traumatico ad attivita' cicatrizzante ed antibattericaInfo
- Publication number
- IT1256111B IT1256111B ITMI922674A ITMI922674A IT1256111B IT 1256111 B IT1256111 B IT 1256111B IT MI922674 A ITMI922674 A IT MI922674A IT MI922674 A ITMI922674 A IT MI922674A IT 1256111 B IT1256111 B IT 1256111B
- Authority
- IT
- Italy
- Prior art keywords
- cicatrizing
- salts
- traumatic acid
- antibacterial activity
- bacteriostatic
- Prior art date
Links
- MAZWDMBCPDUFDJ-UHFFFAOYSA-N trans-Traumatinsaeure Natural products OC(=O)CCCCCCCCC=CC(O)=O MAZWDMBCPDUFDJ-UHFFFAOYSA-N 0.000 title abstract 2
- MAZWDMBCPDUFDJ-VQHVLOKHSA-N traumatic acid Chemical class OC(=O)CCCCCCCC\C=C\C(O)=O MAZWDMBCPDUFDJ-VQHVLOKHSA-N 0.000 title abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 230000003385 bacteriostatic effect Effects 0.000 abstract 2
- 239000000645 desinfectant Substances 0.000 abstract 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 1
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000004332 silver Substances 0.000 abstract 1
- 229940054334 silver cation Drugs 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229940006486 zinc cation Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Abstract
Sali dell'acido traumatico di formula generale (I), in cui B è un catione farmaceuticamente attivo scelto tra:a) un ammonio quaternario b) una ammina primaria, secondaria e terziaria c) il catione di argento o zinco aventi attività cicatrizzante, disinfettante e batteriostatica e relative composizioni farmaceutiche somministrabili topicamente e per via parenterale per il trattamento terapeutico delle patologie cutanee nelle quali accanto all'effetto cicatrizzante è importante associare un effetto disinfettante, antisettico e battereostatico.
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI922674A IT1256111B (it) | 1992-11-23 | 1992-11-23 | Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica |
AT93118531T ATE156354T1 (de) | 1992-11-23 | 1993-11-18 | Salze der cis und trans-traumatinsäure mit wundheilender sowie bacteriostatischer, antiviraler, antibiotischer oder fungizider wirkung |
EP93118531A EP0599188B1 (en) | 1992-11-23 | 1993-11-18 | Trans and CIS traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity |
ES93118531T ES2106942T3 (es) | 1992-11-23 | 1993-11-18 | Sales de acidos trans y cis traumaticos que tienen actividad cicatrizante asociada a actividad bacterioestatica, antivirica, antibiotica o antifungica. |
DE69312870T DE69312870T2 (de) | 1992-11-23 | 1993-11-18 | Salze der CIS und Trans-Traumatinsäure mit wundheilender sowie bacteriostatischer, antiviraler, antibiotischer oder fungizider Wirkung |
DK93118531.8T DK0599188T3 (da) | 1992-11-23 | 1993-11-18 | Trans- og cis-traumatinsyresalte med sårhelende virkning associeret med bakteriostatiske, antivirale, antibiotiske eller antifungale virkninger |
US08/155,153 US5567716A (en) | 1992-11-23 | 1993-11-19 | Trans and cis traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity |
CA002109537A CA2109537A1 (en) | 1992-11-23 | 1993-11-19 | Trans and cis traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity |
JP5317322A JPH072725A (ja) | 1992-11-23 | 1993-11-24 | 静菌活性、抗ウィルス活性、抗生物質活性及び抗真菌活性に関連した瘢痕形成活性を有するトランス及びシス型のトラウマチン酸塩 |
GR970402713T GR3025074T3 (en) | 1992-11-23 | 1997-10-16 | Trans and CIS traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI922674A IT1256111B (it) | 1992-11-23 | 1992-11-23 | Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI922674A0 ITMI922674A0 (it) | 1992-11-23 |
ITMI922674A1 ITMI922674A1 (it) | 1994-05-23 |
IT1256111B true IT1256111B (it) | 1995-11-28 |
Family
ID=11364331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI922674A IT1256111B (it) | 1992-11-23 | 1992-11-23 | Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica |
Country Status (10)
Country | Link |
---|---|
US (1) | US5567716A (it) |
EP (1) | EP0599188B1 (it) |
JP (1) | JPH072725A (it) |
AT (1) | ATE156354T1 (it) |
CA (1) | CA2109537A1 (it) |
DE (1) | DE69312870T2 (it) |
DK (1) | DK0599188T3 (it) |
ES (1) | ES2106942T3 (it) |
GR (1) | GR3025074T3 (it) |
IT (1) | IT1256111B (it) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6576224B1 (en) * | 1999-07-06 | 2003-06-10 | Sinuspharma, Inc. | Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis |
US20020061281A1 (en) * | 1999-07-06 | 2002-05-23 | Osbakken Robert S. | Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis |
US6719987B2 (en) | 2000-04-17 | 2004-04-13 | Nucryst Pharmaceuticals Corp. | Antimicrobial bioabsorbable materials |
FR2809310B1 (fr) * | 2000-05-26 | 2004-02-13 | Centre Nat Rech Scient | Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant |
JP2004505057A (ja) | 2000-07-27 | 2004-02-19 | ニュクリスト ファーマシューティカルズ コーポレーション | 過剰増殖性の皮膚障害および皮膚疾患の処置 |
EP1383520B1 (en) | 2001-04-23 | 2013-09-18 | Smith & Nephew (Overseas) Limited | Medicament containing a metal such as silver, gold, platinum or palladium as an antimicrobial agent and their use in the treatment of inflammation of the mucosa |
KR100447825B1 (ko) * | 2001-11-23 | 2004-09-08 | 주식회사 코리아나화장품 | 트라마트산을 포함하는 콜라겐 생합성 촉진용 화장료 조성물 |
US20030133893A1 (en) * | 2002-01-15 | 2003-07-17 | Degania Silicone Ltd. | Compositions and methods for treating skin ailments |
US7201925B2 (en) | 2002-04-23 | 2007-04-10 | Nueryst Pharmaceuticals Corp. | Treatment of ungual and subungual diseases |
US7258875B2 (en) * | 2003-12-04 | 2007-08-21 | Chiou Consulting, Inc. | Compositions and methods for topical treatment of skin infection |
EP1714644B1 (en) | 2005-04-19 | 2012-08-08 | Innovet Italia S.r.l. | Pharmaceutical compositions for the treatment of chronic ulcerations |
US8865227B2 (en) | 2007-12-20 | 2014-10-21 | Smith & Nephew (Overseas) Limited | Metal carbonate particles and methods of making thereof |
CA2747716A1 (en) * | 2008-12-19 | 2010-06-24 | Pinnacle Pharmaceuticals, Inc. | Phenazopyridine compounds |
ITPI20090027A1 (it) * | 2009-03-12 | 2010-09-13 | Filippo Lulli | Sali fisiologicamente e biologicamente attivi dell'acido cis-e trans-traumatico per il trattamento di piante monocotiledoni e dicotiledoni |
GB201313423D0 (en) | 2013-07-26 | 2013-09-11 | Innospec Ltd | Compositions and methods |
CN113163810A (zh) * | 2018-12-06 | 2021-07-23 | 国际香料和香精公司 | 用于调节味道的愈伤酸组合物和方法 |
WO2020118002A1 (en) * | 2018-12-06 | 2020-06-11 | International Flavors & Fragrances Inc. | Boehmeria nivea compositions and methods for taste modulation |
CN113712950A (zh) * | 2021-08-31 | 2021-11-30 | 上海市同仁医院 | 创伤酸在制备抗肥胖药物或抗肥胖保健品中的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3532636A (en) * | 1968-02-14 | 1970-10-06 | Purex Corp Ltd | Detergent composition |
US3542826A (en) * | 1968-03-22 | 1970-11-24 | Purex Corp Ltd | Cobalt dodecenedioate and use thereof |
US3720773A (en) * | 1970-01-22 | 1973-03-13 | Purex Corp Ltd | Method and composition for the topical treatment of herpetic keratitis |
US3808314A (en) * | 1970-01-22 | 1974-04-30 | Purex Corp Ltd | Cobalt dodecenedioate for treating canine pyometritis |
-
1992
- 1992-11-23 IT ITMI922674A patent/IT1256111B/it active IP Right Grant
-
1993
- 1993-11-18 AT AT93118531T patent/ATE156354T1/de not_active IP Right Cessation
- 1993-11-18 DE DE69312870T patent/DE69312870T2/de not_active Expired - Fee Related
- 1993-11-18 ES ES93118531T patent/ES2106942T3/es not_active Expired - Lifetime
- 1993-11-18 EP EP93118531A patent/EP0599188B1/en not_active Expired - Lifetime
- 1993-11-18 DK DK93118531.8T patent/DK0599188T3/da active
- 1993-11-19 US US08/155,153 patent/US5567716A/en not_active Expired - Lifetime
- 1993-11-19 CA CA002109537A patent/CA2109537A1/en not_active Abandoned
- 1993-11-24 JP JP5317322A patent/JPH072725A/ja active Pending
-
1997
- 1997-10-16 GR GR970402713T patent/GR3025074T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5567716A (en) | 1996-10-22 |
DE69312870T2 (de) | 1998-01-15 |
ITMI922674A1 (it) | 1994-05-23 |
DE69312870D1 (de) | 1997-09-11 |
ATE156354T1 (de) | 1997-08-15 |
EP0599188B1 (en) | 1997-08-06 |
DK0599188T3 (da) | 1998-02-02 |
ITMI922674A0 (it) | 1992-11-23 |
GR3025074T3 (en) | 1998-01-30 |
ES2106942T3 (es) | 1997-11-16 |
CA2109537A1 (en) | 1994-05-24 |
EP0599188A1 (en) | 1994-06-01 |
JPH072725A (ja) | 1995-01-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971128 |