HUP0202781A3 - Betha-carboline particulate form, pharmaceutical compositions containing it, their preparations and their use - Google Patents

Betha-carboline particulate form, pharmaceutical compositions containing it, their preparations and their use

Info

Publication number
HUP0202781A3
HUP0202781A3 HU0202781A HUP0202781A HUP0202781A3 HU P0202781 A3 HUP0202781 A3 HU P0202781A3 HU 0202781 A HU0202781 A HU 0202781A HU P0202781 A HUP0202781 A HU P0202781A HU P0202781 A3 HUP0202781 A3 HU P0202781A3
Authority
HU
Hungary
Prior art keywords
betha
carboline
preparations
pharmaceutical compositions
compositions containing
Prior art date
Application number
HU0202781A
Other languages
English (en)
Original Assignee
Lilly Icos Llc Wilmington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22520112&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0202781(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Icos Llc Wilmington filed Critical Lilly Icos Llc Wilmington
Publication of HUP0202781A2 publication Critical patent/HUP0202781A2/hu
Publication of HUP0202781A3 publication Critical patent/HUP0202781A3/hu
Publication of HU229443B1 publication Critical patent/HU229443B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0202781A 1999-08-03 2000-08-01 Betha-carboline particulate form, pharmaceutical compositions containing it, their preparations and their use HU229443B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14704899P 1999-08-03 1999-08-03
PCT/US2000/020981 WO2001008688A2 (en) 1999-08-03 2000-08-01 Beta-carboline drug products

Publications (3)

Publication Number Publication Date
HUP0202781A2 HUP0202781A2 (hu) 2002-12-28
HUP0202781A3 true HUP0202781A3 (en) 2003-10-28
HU229443B1 HU229443B1 (en) 2013-12-30

Family

ID=22520112

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202781A HU229443B1 (en) 1999-08-03 2000-08-01 Betha-carboline particulate form, pharmaceutical compositions containing it, their preparations and their use

Country Status (33)

Country Link
EP (1) EP1200092B1 (hu)
JP (1) JP4456788B2 (hu)
KR (1) KR20020063842A (hu)
CN (2) CN1377270A (hu)
AR (1) AR033953A1 (hu)
AT (1) ATE264680T1 (hu)
AU (1) AU773666B2 (hu)
BR (1) BR0012901A (hu)
CA (1) CA2380087C (hu)
CO (1) CO5200849A1 (hu)
CZ (1) CZ300151B6 (hu)
DE (1) DE60010089T2 (hu)
DK (1) DK1200092T3 (hu)
DZ (1) DZ3180A1 (hu)
EA (1) EA004302B9 (hu)
ES (1) ES2220506T3 (hu)
HK (1) HK1044278B (hu)
HR (1) HRP20020091B1 (hu)
HU (1) HU229443B1 (hu)
IL (1) IL147642A0 (hu)
MX (1) MXPA02001197A (hu)
MY (1) MY125428A (hu)
NO (1) NO321602B1 (hu)
NZ (1) NZ516613A (hu)
PE (1) PE20010480A1 (hu)
PL (1) PL199469B1 (hu)
PT (1) PT1200092E (hu)
SK (1) SK286365B6 (hu)
SV (1) SV2002000137A (hu)
TW (1) TWI235658B (hu)
UA (1) UA71629C2 (hu)
WO (1) WO2001008688A2 (hu)
ZA (1) ZA200200825B (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0012863A (pt) * 1999-08-03 2002-04-16 Lilly Icos Llc Composições farmacêuticas de "beta"-carbolina
EP1804582A4 (en) * 2004-10-28 2009-12-09 Reddys Lab Ltd Dr POLYMORPH SHAPES OF TADALAFIL
ATE419837T1 (de) 2006-01-05 2009-01-15 Teva Pharma Feuchtgranulierungsmethode zur herstellung pharmazeutischer aripiprazolzusammensetzungen
DE102007028869A1 (de) * 2007-06-22 2008-12-24 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil
MD4009C2 (ro) * 2008-07-15 2010-08-31 Институт Химии Академии Наук Молдовы Utilizarea 1-metil-4-(N-metilaminobutil-4)-β-carbolinei în calitate de remediu antituberculos
DE102009033396A1 (de) 2009-07-16 2011-01-20 Ratiopharm Gmbh Wässrige Lösung und gelatinierte Zusammensetzung umfassend einen Phosphodiesterase-5-Inhibitor sowie diesbezügliche Verfahren und Verwendung
DE102009035211A1 (de) 2009-07-29 2011-02-17 Ratiopharm Gmbh Copräzipitate umfassend einen Phosphodiesterase-5-Inhibitor (PDE-5-Inhibitor) und einen pharmazeutisch verträglichen Trägerstoff, ihre Herstellung und Verwendung
WO2012085927A2 (en) * 2010-12-02 2012-06-28 Mylan Laboratories, Limited Tadalafil compositions
WO2012095151A1 (en) 2010-12-23 2012-07-19 Zaklady Farmaceutyczne Polpharma Sa Solid pharmaceutical dosage forms comprising tadalafil and methods of preparation thereof
RU2013141446A (ru) 2011-02-10 2015-03-20 Синтон Бв Фармацевтическая композиция, содержащая тадалафил и циклодекстрин
WO2012107092A1 (en) 2011-02-10 2012-08-16 Synthon Bv Pharmaceutical composition comprising tadalafil and a cyclodextrin
EP2672959A1 (en) 2011-02-10 2013-12-18 Synthon BV Granulated composition comprising tadalafil and a disintegrant
JP5930686B2 (ja) * 2011-12-07 2016-06-08 株式会社トクヤマ 溶解性および安定性の向上した難溶性医薬品原体及びその製造方法
JP6254107B2 (ja) 2012-03-15 2017-12-27 メルク パテント ゲーエムベーハー 電子素子
WO2014003677A1 (en) * 2012-06-28 2014-01-03 Xspray Microparticles Ab Pharmaceutical compositions comprising solid dispersion particles containing tadalafil
WO2014003678A1 (en) * 2012-06-28 2014-01-03 Xspray Microparticles Ab Pharmaceutical compositions comprising ambrisentan and solid dispersion particles containing tadalafil
CN105310984A (zh) * 2014-06-10 2016-02-10 合肥贝霓医药科技有限公司 一种pde5抑制剂的超微粉体及其制备方法
PL3111929T3 (pl) * 2014-06-24 2019-01-31 Wooshin Labottach Co., Ltd. Ulegający rozpadowi w jamie ustnej preparat w postaci błony zawierający tadalafil i sposób jego wytwarzania
SI3466951T1 (sl) 2014-07-23 2022-05-31 Krka, D.D., Novo Mesto Proces za pripravo zaviralca CGMP-fosfodiesteraze in oralne farmacevtske formulacije, ki obsega koprecipitate tadalafila
JP2016106139A (ja) * 2016-03-07 2016-06-16 株式会社トクヤマ 溶解性および安定性の向上した難溶性医薬品原体及びその製造方法
SG11202006080SA (en) * 2017-12-26 2020-07-29 Ftf Pharma Private Ltd Liquid oral formulations for pde v inhibitors
RS60973B1 (sr) 2018-01-10 2020-11-30 Gap S A Meke želatinske kapsule koje sadrže suspenziju tadalafila
CN110638770B (zh) * 2019-10-25 2022-04-05 株洲千金药业股份有限公司 他达拉非片剂的制备方法及以该方法制得的片剂
WO2023227185A1 (en) * 2022-05-27 2023-11-30 Rontis Hellas S.A. Improved pharmaceutical composition containing tadalafil and nanomilling process for the preparation thereof
CN119112817A (zh) * 2024-08-20 2024-12-13 武汉九珑人福药业有限责任公司 一种他达拉非片及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618845A (en) * 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
GB9511220D0 (en) * 1995-06-02 1995-07-26 Glaxo Group Ltd Solid dispersions

Also Published As

Publication number Publication date
DK1200092T3 (da) 2004-08-16
EP1200092B1 (en) 2004-04-21
NO20020531D0 (no) 2002-02-01
CO5200849A1 (es) 2002-09-27
AR033953A1 (es) 2004-01-21
MXPA02001197A (es) 2003-02-12
HK1044278A1 (en) 2002-10-18
HK1044278B (en) 2004-10-08
UA71629C2 (en) 2004-12-15
SV2002000137A (es) 2002-06-07
JP4456788B2 (ja) 2010-04-28
HUP0202781A2 (hu) 2002-12-28
TWI235658B (en) 2005-07-11
BR0012901A (pt) 2002-04-16
NZ516613A (en) 2003-08-29
CA2380087A1 (en) 2001-02-08
IL147642A0 (en) 2002-08-14
CA2380087C (en) 2007-05-01
NO20020531L (no) 2002-04-03
ES2220506T3 (es) 2004-12-16
DE60010089T2 (de) 2004-10-14
DE60010089D1 (de) 2004-05-27
HRP20020091B1 (en) 2006-02-28
JP2003505510A (ja) 2003-02-12
SK286365B6 (sk) 2008-08-05
HU229443B1 (en) 2013-12-30
EA004302B9 (ru) 2019-01-31
WO2001008688A2 (en) 2001-02-08
AU6508400A (en) 2001-02-19
CZ2002387A3 (cs) 2002-10-16
CZ300151B6 (cs) 2009-02-25
ZA200200825B (en) 2003-04-30
PL199469B1 (pl) 2008-09-30
ATE264680T1 (de) 2004-05-15
EA200200119A1 (ru) 2002-06-27
SK1722002A3 (en) 2002-05-09
PL353268A1 (en) 2003-11-03
PT1200092E (pt) 2004-07-30
KR20020063842A (ko) 2002-08-05
AU773666B2 (en) 2004-06-03
EA004302B1 (ru) 2004-02-26
PE20010480A1 (es) 2001-05-26
HRP20020091A2 (en) 2004-02-29
NO321602B1 (no) 2006-06-12
DZ3180A1 (fr) 2001-02-08
WO2001008688A3 (en) 2001-08-16
EP1200092A2 (en) 2002-05-02
CN101134019A (zh) 2008-03-05
MY125428A (en) 2006-07-31
CN1377270A (zh) 2002-10-30

Similar Documents

Publication Publication Date Title
HUP0202781A3 (en) Betha-carboline particulate form, pharmaceutical compositions containing it, their preparations and their use
HUP0200714A3 (en) Pharmaceutical compounds, pharmaceutical compositions containing them and their use
HUP0204081A3 (en) 4-pyrimidinyl-n-acyl-l-phenylalanines, pharmaceutical compositions containing them and their use
ZA200110022B (en) Thiazoloderivatives and pharmaceutical compositions containing them.
HUP0204514A3 (en) Pyridinylimidazoles, pharmaceutical compositions containing them and their use
HUP0400837A3 (en) 2-phenyl-thiazole derivatives, their use and pharmaceutical compositions containing them
HUP0204474A3 (en) 1h-imidazopyridine derivatives, pharmaceutical compositions containing them and their use
HUP0302969A3 (en) Npyy5 antagonists, pharmaceutical compositions containing them and their use
HUP0203939A3 (en) Pharmaceutical compounds and compositions containing them and their use
IL150224A0 (en) Lipopeptides and pharmaceutical compositions containing the same
HUP0204413A3 (en) Quinazoline compounds, their preparation, their use and pharmaceutical compositions containing them
IL152451A0 (en) 2-chloro-2-nitrophenylcarboxamide derivatives and pharmaceutical compositions containing the same
HUP0301178A3 (en) Glucopyranosyloxybenzylbenzene derivatives and pharmaceutical compositions containing the same
IL153123A0 (en) N-ureidoheterocycloalkyl-piperidine derivatives and pharmaceutical compositions containing the same
IL150223A0 (en) Lipopeptides and pharmaceutical compositions containing the same
IL151952A0 (en) Aminopyridine derivatives and pharmaceutical compositions containing the same
HUP0105003A2 (en) 2-oxy-4h-3,1-benzoxazin-4-one derivatives, their use and pharmaceutical compositions containing them
HUP0200155A3 (en) Thioamide derivatives, pharmaceutical compositions containing them and their use
HUP0103884A3 (en) Arylsulfonanilide urea-derivatives, pharmaceutical compositions containing them and their use
HUP0301573A3 (en) Substituted arylpyrazines, pharmaceutical compositions containing them and their use
HUP0203194A3 (en) Phenylpiperazines, pharmaceutical compositions containing them and their use
HUP0002272A3 (en) Aroyl-piperazine derivatives, their preparation pharmaceutical compositions containing them and their use
HUP0203735A3 (en) 4-pyridinyl-n-acyl-l-phenylalanines, pharmaceutical compositions containing them and their use
HUP0400967A3 (en) Substituted 2-anilino-benzimidazoles, their use and pharmaceutical compositions containing them
IL147214A0 (en) 1-methylcarbapenem derivatives and pharmaceutical compositions containing the same

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: ICOS CORPORATION, US

Free format text: FORMER OWNER(S): LILLY ICOS LLC, US