HUP0200650A3 - Microbial process for preparing pravastatin - Google Patents
Microbial process for preparing pravastatinInfo
- Publication number
- HUP0200650A3 HUP0200650A3 HU0200650A HUP0200650A HUP0200650A3 HU P0200650 A3 HUP0200650 A3 HU P0200650A3 HU 0200650 A HU0200650 A HU 0200650A HU P0200650 A HUP0200650 A HU P0200650A HU P0200650 A3 HUP0200650 A3 HU P0200650A3
- Authority
- HU
- Hungary
- Prior art keywords
- microbial process
- preparing pravastatin
- pravastatin
- preparing
- microbial
- Prior art date
Links
- TUZYXOIXSAXUGO-UHFFFAOYSA-N Pravastatin Natural products C1=CC(C)C(CCC(O)CC(O)CC(O)=O)C2C(OC(=O)C(C)CC)CC(O)C=C21 TUZYXOIXSAXUGO-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000007483 microbial process Effects 0.000 title 1
- TUZYXOIXSAXUGO-PZAWKZKUSA-N pravastatin Chemical compound C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 TUZYXOIXSAXUGO-PZAWKZKUSA-N 0.000 title 1
- 229960002965 pravastatin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11845899P | 1999-02-03 | 1999-02-03 | |
| US13475999P | 1999-05-18 | 1999-05-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0200650A2 HUP0200650A2 (en) | 2002-08-28 |
| HUP0200650A3 true HUP0200650A3 (en) | 2008-03-28 |
Family
ID=26816384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0200650A HUP0200650A3 (en) | 1999-02-03 | 2000-02-03 | Microbial process for preparing pravastatin |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1154979B1 (cs) |
| JP (2) | JP3645491B2 (cs) |
| KR (2) | KR20060061406A (cs) |
| CN (3) | CN1590363A (cs) |
| AR (2) | AR023368A1 (cs) |
| AT (1) | ATE294771T1 (cs) |
| AU (2) | AU774438B2 (cs) |
| BG (1) | BG105778A (cs) |
| BR (1) | BR0009180A (cs) |
| CA (1) | CA2361701C (cs) |
| CZ (1) | CZ20012761A3 (cs) |
| DE (1) | DE60019898T2 (cs) |
| ES (1) | ES2240072T3 (cs) |
| HK (1) | HK1042686B (cs) |
| HR (1) | HRP20010577B1 (cs) |
| HU (1) | HUP0200650A3 (cs) |
| IL (1) | IL144697A0 (cs) |
| IS (1) | IS6036A (cs) |
| MX (1) | MXPA01007807A (cs) |
| NO (1) | NO20013818L (cs) |
| PL (1) | PL350317A1 (cs) |
| PT (1) | PT1154979E (cs) |
| RU (1) | RU2004127981A (cs) |
| SK (1) | SK10932001A3 (cs) |
| TR (2) | TR200600009T2 (cs) |
| WO (1) | WO2000046175A1 (cs) |
| YU (1) | YU55701A (cs) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI20305A (sl) * | 1999-08-06 | 2001-02-28 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Kristali natrijeve soli pravastatina |
| EP1798214A3 (en) * | 1999-11-30 | 2007-08-01 | Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság | Process for recovering statin compounds from a fermentation broth |
| AU1804601A (en) * | 1999-11-30 | 2001-06-12 | Biogal Gyogyszergyar Rt | Process for recovering statin compounds from a fermentation broth |
| SK8312002A3 (en) | 1999-12-14 | 2003-05-02 | Biogal Gyogyszergyar | Novel forms of pravastatin sodium |
| WO2002030415A1 (en) * | 2000-10-05 | 2002-04-18 | Biogal Gyogyszergyar Rt | Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same |
| JP2003026634A (ja) * | 2001-07-17 | 2003-01-29 | Mercian Corp | プラバスタチンナトリウム塩の製造方法 |
| KR100540761B1 (ko) * | 2002-08-09 | 2006-01-16 | 코바이오텍 (주) | 프라바스타틴 나트륨의 제조방법 |
| EP1452519A1 (en) * | 2003-02-25 | 2004-09-01 | Balkanpharma-Razgrad AD | Method for the isolation and purification of pravastatin sodium |
| CA2523233C (en) * | 2003-04-25 | 2012-03-20 | Nippon Chemiphar Co., Ltd. | Salt of (2s,3s)-3-[[(1s)-1-isobutoxymethyl-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid |
| CN1244688C (zh) | 2003-07-09 | 2006-03-08 | 上海天伟生物制药有限公司 | 生产普伐他汀钠的微生物和方法 |
| ATE412409T1 (de) | 2003-11-24 | 2008-11-15 | Teva Gyogyszergyar Zartkoeruee | Verfahren zur reinigung von pravastatin |
| TWI307360B (en) | 2004-12-03 | 2009-03-11 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Process for constructing strain having compactin hydroxylation ability |
| ES2378614T3 (es) * | 2008-04-02 | 2012-04-16 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Extracción de pravastatina |
| EP3714959A1 (en) * | 2019-03-29 | 2020-09-30 | Basf Se | Isolation of small molecules from the fermentation broth of a eukaryotic microorganism |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1369474A1 (en) * | 1996-03-28 | 2003-12-10 | DSM IP Assets B.V. | Process for the preparation of a granular microbial biomass and isolation of valuable compounds therefrom |
-
2000
- 2000-02-03 EP EP00911709A patent/EP1154979B1/en not_active Expired - Lifetime
- 2000-02-03 JP JP2000597248A patent/JP3645491B2/ja not_active Expired - Fee Related
- 2000-02-03 PT PT00911709T patent/PT1154979E/pt unknown
- 2000-02-03 CN CNA2004100456608A patent/CN1590363A/zh active Pending
- 2000-02-03 KR KR1020067009407A patent/KR20060061406A/ko not_active Application Discontinuation
- 2000-02-03 IL IL14469700A patent/IL144697A0/xx not_active IP Right Cessation
- 2000-02-03 HU HU0200650A patent/HUP0200650A3/hu unknown
- 2000-02-03 SK SK1093-2001A patent/SK10932001A3/sk unknown
- 2000-02-03 CN CNB008058792A patent/CN1177793C/zh not_active Expired - Fee Related
- 2000-02-03 CN CNB2003101233833A patent/CN1260344C/zh not_active Expired - Fee Related
- 2000-02-03 AU AU33567/00A patent/AU774438B2/en not_active Ceased
- 2000-02-03 CA CA002361701A patent/CA2361701C/en not_active Expired - Fee Related
- 2000-02-03 BR BR0009180-4A patent/BR0009180A/pt not_active Application Discontinuation
- 2000-02-03 ES ES00911709T patent/ES2240072T3/es not_active Expired - Lifetime
- 2000-02-03 YU YU55701A patent/YU55701A/sh unknown
- 2000-02-03 DE DE60019898T patent/DE60019898T2/de not_active Expired - Fee Related
- 2000-02-03 AT AT00911709T patent/ATE294771T1/de not_active IP Right Cessation
- 2000-02-03 TR TR2006/00009T patent/TR200600009T2/xx unknown
- 2000-02-03 PL PL00350317A patent/PL350317A1/xx unknown
- 2000-02-03 TR TR2001/03127T patent/TR200103127T2/xx unknown
- 2000-02-03 MX MXPA01007807A patent/MXPA01007807A/es unknown
- 2000-02-03 CZ CZ20012761A patent/CZ20012761A3/cs unknown
- 2000-02-03 WO PCT/US2000/002993 patent/WO2000046175A1/en active IP Right Grant
- 2000-02-03 KR KR1020017009821A patent/KR100648541B1/ko not_active IP Right Cessation
- 2000-02-04 AR ARP000100484A patent/AR023368A1/es unknown
-
2001
- 2001-07-31 HR HR20010577A patent/HRP20010577B1/xx not_active IP Right Cessation
- 2001-08-02 IS IS6036A patent/IS6036A/is unknown
- 2001-08-03 BG BG105778A patent/BG105778A/bg unknown
- 2001-08-03 NO NO20013818A patent/NO20013818L/no not_active Application Discontinuation
-
2002
- 2002-05-07 HK HK02103449.9A patent/HK1042686B/zh not_active IP Right Cessation
-
2004
- 2004-09-01 JP JP2004254575A patent/JP4197312B2/ja not_active Expired - Fee Related
- 2004-09-22 RU RU2004127981/04A patent/RU2004127981A/ru not_active Application Discontinuation
- 2004-09-24 AU AU2004214559A patent/AU2004214559A1/en not_active Abandoned
-
2007
- 2007-06-29 AR ARP070102941A patent/AR061765A2/es not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0203206A3 (en) | Process for preparing 4-trifluoromethylsulphinylpyrazole derivative | |
| IL147588A0 (en) | Microbial process for preparing pravastatin | |
| HRP20010577B1 (en) | Microbial process for preparing pravastatin | |
| GB9905512D0 (en) | Process | |
| GB9908814D0 (en) | Process | |
| GB2351668B (en) | Autoclaves | |
| IL139178A0 (en) | Process for preparing esterefied chroman compounds | |
| GB9904162D0 (en) | Process | |
| HUP0103002A3 (en) | New process for obtaining 17betha-(n-terc-butylcarbamoyl)-3-one-4-aza-steroids | |
| HUP0000559A3 (en) | Process for preparing cyanoaceticacidesters | |
| GB2349325B (en) | Plant supports | |
| SI1154979T1 (en) | Microbial process for preparing pravastatin | |
| GB9905418D0 (en) | Process | |
| GB9906206D0 (en) | Fermentation apparatus | |
| GB9903087D0 (en) | Process | |
| AU1725400A (en) | Process for preparing acylaromatic compounds | |
| GB2360770B (en) | Process for preparing pentinoic esters | |
| GB9907836D0 (en) | Carbonylation process | |
| PL109156U1 (en) | Fermentation apparatus | |
| HU9900106V0 (en) | Support for litterbag | |
| GB9920708D0 (en) | Support for plants | |
| GB9913672D0 (en) | Culture method | |
| TW387241U (en) | Air-whistle for kettle | |
| TW385657U (en) | Robbery-prevention apparatus for drawer | |
| GB9900074D0 (en) | Process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |