HUP0002982A2 - Lamivudint tartalmazó folyékony gyógyszerkészítmény - Google Patents

Lamivudint tartalmazó folyékony gyógyszerkészítmény

Info

Publication number
HUP0002982A2
HUP0002982A2 HU0002982A HUP0002982A HUP0002982A2 HU P0002982 A2 HUP0002982 A2 HU P0002982A2 HU 0002982 A HU0002982 A HU 0002982A HU P0002982 A HUP0002982 A HU P0002982A HU P0002982 A2 HUP0002982 A2 HU P0002982A2
Authority
HU
Hungary
Prior art keywords
lamivudine
liquid compositions
thiacytidine
oxathiolan
epivir
Prior art date
Application number
HU0002982A
Other languages
English (en)
Inventor
Warren M. Casey
Ngoc-Anh Thi Nguyen
Original Assignee
Glaxo Group Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9706295.4A external-priority patent/GB9706295D0/en
Application filed by Glaxo Group Ltd. filed Critical Glaxo Group Ltd.
Publication of HUP0002982A2 publication Critical patent/HUP0002982A2/hu
Publication of HUP0002982A3 publication Critical patent/HUP0002982A3/hu
Publication of HU225600B1 publication Critical patent/HU225600B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Atalálmány tárgyát új gyógyászati készítmények képezik, amelyek(2R,cisz)-4-amino-1-(2-hidroxi-metil-1,3-oxatiolán-5-il)-(1H)-pirimidin-2-ont[(-)-2',3'-didezoxi-3'-tiacitidin, Epivir<, lamivudin]tartalmaznak, valamint ezek alkalmazása a gyógyászatban. Ó
HU0002982A 1997-03-24 1998-03-20 Liquid compositions comprising lamivudine HU225600B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4235397P 1997-03-24 1997-03-24
GBGB9706295.4A GB9706295D0 (en) 1997-03-26 1997-03-26 Lamivudine formulation
PCT/EP1998/001626 WO1998042321A2 (en) 1997-03-24 1998-03-20 Liquid compositions comprising lamivudine

Publications (3)

Publication Number Publication Date
HUP0002982A2 true HUP0002982A2 (hu) 2001-01-29
HUP0002982A3 HUP0002982A3 (en) 2001-12-28
HU225600B1 HU225600B1 (en) 2007-05-02

Family

ID=26311267

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002982A HU225600B1 (en) 1997-03-24 1998-03-20 Liquid compositions comprising lamivudine

Country Status (40)

Country Link
US (1) US6004968A (hu)
EP (1) EP0969815B1 (hu)
JP (1) JP3264937B2 (hu)
KR (1) KR100484695B1 (hu)
CN (1) CN1191061C (hu)
AP (1) AP1141A (hu)
AR (1) AR011697A1 (hu)
AT (1) ATE295150T1 (hu)
AU (1) AU728461B2 (hu)
BG (1) BG64690B1 (hu)
BR (1) BR9808060B1 (hu)
CA (1) CA2286126C (hu)
CO (1) CO4980849A1 (hu)
CY (1) CY2569B1 (hu)
CZ (1) CZ298008B6 (hu)
DE (1) DE69830154T2 (hu)
EA (1) EA001990B1 (hu)
EE (1) EE03996B1 (hu)
ES (1) ES2239802T3 (hu)
HK (1) HK1022853A1 (hu)
HN (1) HN1998000045A (hu)
HR (1) HRP980154B1 (hu)
HU (1) HU225600B1 (hu)
ID (1) ID29294A (hu)
IL (1) IL131917A0 (hu)
IS (1) IS2515B (hu)
MY (1) MY116242A (hu)
NO (1) NO326719B1 (hu)
NZ (1) NZ337798A (hu)
PA (1) PA8449301A1 (hu)
PE (1) PE61699A1 (hu)
PL (1) PL190505B1 (hu)
PT (1) PT969815E (hu)
RS (1) RS49772B (hu)
SI (1) SI0969815T1 (hu)
SK (1) SK283417B6 (hu)
SV (1) SV1998000040A (hu)
TW (1) TW536403B (hu)
UY (1) UY24930A1 (hu)
WO (1) WO1998042321A2 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ333099A (en) 1996-06-25 2000-06-23 Glaxo Group Ltd synergistic combinations comprising 141W94, zidovudine and 3TC for use in the treatment of HIV
US6018044A (en) * 1998-01-02 2000-01-25 Roche Vitamins Inc. Light screening compositions
US6432966B2 (en) * 1999-10-29 2002-08-13 Smithkline Beecham Corporation Antiviral combinations
JP2003039582A (ja) * 2001-07-19 2003-02-13 Three M Innovative Properties Co 湿潤防滑性シート及び湿潤防滑構造体
US6855346B2 (en) * 2001-10-05 2005-02-15 Tzu-Sheng Wu Pharmaceutical composition having prophylactic effects on lamivudine-related disease relapse and drug resistance and methods of using the same
TWI275392B (en) * 2002-04-08 2007-03-11 Bristol Myers Squibb Co Low dose liquid entecavir formulations and use
WO2004075913A1 (ja) 2003-02-28 2004-09-10 Chugai Seiyaku Kabushiki Kaisha タンパク質含有安定化製剤
US20040228804A1 (en) * 2003-05-16 2004-11-18 Jones Alonzo H. Nasal administration of xylitol to a non-human mammal
PE20060484A1 (es) * 2004-07-14 2006-07-06 Ucb Farchim Sa Preparaciones farmaceuticas liquidas que comprenden un compuesto de benzhidril piperizina
CN100427082C (zh) * 2005-08-02 2008-10-22 盛华（广州）医药科技有限公司 羟基苯甲酸酯及其类似物在制备预防和治疗病毒性感染药物中的应用
WO2009092002A1 (en) * 2008-01-17 2009-07-23 Duquesne University Of The Holy Spirit Antiretroviral drug formulations for treatment of children exposed to hiv/aids
RU2587782C1 (ru) * 2015-01-19 2016-06-20 Общество с ограниченной ответственностью "Трейдсервис" Стабильная фармацевтическая композиция ламивудина

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047407A (en) * 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
DK0513917T4 (da) * 1991-05-16 2001-06-25 Glaxo Group Ltd Antivirale kombinationer indeholdende nukleosidanaloger
GB9111902D0 (en) * 1991-06-03 1991-07-24 Glaxo Group Ltd Chemical compounds
GB9503850D0 (en) * 1995-02-25 1995-04-19 Glaxo Group Ltd Medicaments
MY115461A (en) * 1995-03-30 2003-06-30 Wellcome Found Synergistic combinations of zidovudine, 1592u89 and 3tc
GB9605293D0 (en) * 1996-03-13 1996-05-15 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
AP1141A (en) 2003-01-29
EE03996B1 (et) 2003-04-15
EP0969815B1 (en) 2005-05-11
HUP0002982A3 (en) 2001-12-28
CZ340399A3 (cs) 2000-04-12
IS2515B (is) 2009-06-15
HN1998000045A (es) 1999-03-19
NZ337798A (en) 2001-03-30
HRP980154B1 (en) 2002-06-30
EP0969815A2 (en) 2000-01-12
IL131917A (en) 2001-01-11
HK1022853A1 (en) 2000-08-25
HU225600B1 (en) 2007-05-02
UY24930A1 (es) 2000-10-31
KR100484695B1 (ko) 2005-04-22
JP2001501974A (ja) 2001-02-13
SI0969815T1 (hu) 2005-08-31
WO1998042321A2 (en) 1998-10-01
TW536403B (en) 2003-06-11
CN1191061C (zh) 2005-03-02
CO4980849A1 (es) 2000-11-27
BR9808060B1 (pt) 2009-05-05
NO994619D0 (no) 1999-09-23
PL190505B1 (pl) 2005-12-30
CA2286126C (en) 2003-08-12
JP3264937B2 (ja) 2002-03-11
BR9808060A (pt) 2000-03-08
ATE295150T1 (de) 2005-05-15
BG64690B1 (bg) 2005-12-30
US6004968A (en) 1999-12-21
AU7208498A (en) 1998-10-20
RS49772B (sr) 2008-06-05
MY116242A (en) 2003-12-31
CY2569B1 (en) 2008-07-02
HRP980154A2 (en) 1998-12-31
NO994619L (no) 1999-11-23
EA199900757A1 (ru) 2000-08-28
WO1998042321A3 (en) 1999-01-07
CN1255849A (zh) 2000-06-07
IS5184A (is) 1999-09-17
EA001990B1 (ru) 2001-10-22
DE69830154D1 (de) 2005-06-16
BG103818A (en) 2000-06-30
DE69830154T2 (de) 2005-10-13
ES2239802T3 (es) 2005-10-01
PA8449301A1 (es) 2000-05-24
CA2286126A1 (en) 1998-10-01
AR011697A1 (es) 2000-08-30
IL131917A0 (en) 2001-03-19
PL336038A1 (en) 2000-06-05
SV1998000040A (es) 1999-03-16
PE61699A1 (es) 1999-07-08
YU47799A (sh) 2002-06-19
CZ298008B6 (cs) 2007-05-23
EE9900440A (et) 2000-04-17
ID29294A (id) 2001-08-16
KR20010005624A (ko) 2001-01-15
AU728461B2 (en) 2001-01-11
AP9901657A0 (en) 1999-09-30
SK129999A3 (en) 2000-07-11
SK283417B6 (sk) 2003-07-01
PT969815E (pt) 2005-07-29
NO326719B1 (no) 2009-02-02

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